sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4p6w | MOF | Glucocorticoid receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4p6w | MOF | Glucocorticoid receptor | / | 1.000 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.581 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.579 | |
| 4udc | DEX | Glucocorticoid receptor | / | 0.558 | |
| 2w8y | 486 | Progesterone receptor | / | 0.555 | |
| 3zrb | ORC | Progesterone receptor | / | 0.553 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.544 | |
| 2w8y | NDR | Progesterone receptor | / | 0.537 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.534 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.534 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.530 | |
| 1m2z | DEX | Glucocorticoid receptor | / | 0.529 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.526 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.524 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.523 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.521 | |
| 1sqn | NDR | Progesterone receptor | / | 0.518 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.512 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.511 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.511 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.510 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.508 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.508 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.507 | |
| 3d90 | NOG | Progesterone receptor | / | 0.507 | |
| 3mne | DEX | Glucocorticoid receptor | / | 0.506 | |
| 2p15 | EZT | Estrogen receptor | / | 0.504 | |
| 2pix | DHT | Androgen receptor | / | 0.503 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.502 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.497 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.496 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.495 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.495 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.493 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.493 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.490 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.490 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.490 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.490 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.489 | |
| 2pio | DHT | Androgen receptor | / | 0.489 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.489 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.489 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.488 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.488 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.487 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.487 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.486 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.486 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.486 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.485 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.485 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.484 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.484 | |
| 1xny | BTN | Propionyl-CoA carboxylase complex B subunit | / | 0.483 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.482 | |
| 2ab2 | SNL | Mineralocorticoid receptor | / | 0.482 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.482 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.481 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.481 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.480 | |
| 2pkl | DHT | Androgen receptor | / | 0.480 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.480 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.480 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.480 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.480 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.480 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.479 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.479 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.479 | |
| 2aa6 | STR | Mineralocorticoid receptor | / | 0.478 | |
| 2aa7 | 1CA | Mineralocorticoid receptor | / | 0.478 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.478 | |
| 3mno | DEX | Glucocorticoid receptor | / | 0.478 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.478 | |
| 4apu | OR8 | Progesterone receptor | / | 0.478 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.477 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.476 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.476 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.475 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.475 | |
| 2ou5 | FMN | Pyridoxamine 5'-phosphate oxidase-related FMN-binding protein | / | 0.475 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.475 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.475 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.474 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.474 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.474 | |
| 1osv | CHC | Bile acid receptor | / | 0.473 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.473 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.473 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.473 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.473 | |
| 1e3k | R18 | Progesterone receptor | / | 0.472 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.472 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.472 | |
| 3gob | HXX | DdmC | / | 0.472 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.472 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.471 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.471 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.471 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.470 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.470 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.470 | |
| 3cse | N22 | Uncharacterized protein | / | 0.470 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.470 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.469 | |
| 2g44 | T3O | Estrogen receptor | / | 0.469 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.469 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.469 | |
| 3iqe | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.469 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.469 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.469 | |
| 3zra | ORB | Progesterone receptor | / | 0.469 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.469 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.468 | |
| 1qzz | SAM | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.468 | |
| 2y3r | TRK | TamL | / | 0.468 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.468 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.468 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.467 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.467 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.467 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.467 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.466 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.466 | |
| 3p9t | TCL | Repressor | / | 0.466 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.466 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.466 | |
| 4iah | 1DX | Alr2278 protein | / | 0.466 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 3mje | NDP | AmphB | / | 0.465 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.464 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.464 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.464 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.464 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.464 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.464 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.464 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.464 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.463 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.463 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.463 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4egn | TWO | Cytochrome P450 | / | 0.463 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.462 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.462 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.462 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.462 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.462 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.462 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.461 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.461 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.461 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.461 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.461 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.460 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.460 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 3zux | TCH | Transporter | / | 0.460 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.460 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.459 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.459 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.459 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.459 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.459 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.459 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.458 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.458 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.458 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.458 | |
| 2uzh | IPE | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.458 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.458 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.458 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.458 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.458 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.458 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.458 | |
| 5a3b | APR | SIR2 family protein | / | 0.458 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.458 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.457 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.457 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.457 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.457 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.457 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.457 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.457 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.457 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.457 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.456 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.456 | |
| 1fml | RTL | Retinol dehydratase | / | 0.456 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.456 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.456 | |
| 3qly | 55V | Uncharacterized protein | / | 0.456 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.456 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.456 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.456 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.456 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.456 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.456 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.456 | |
| 4kwh | NAP | Reductase homolog | / | 0.456 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.455 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2wpx | ACO | Orf14 | / | 0.455 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.455 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.455 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.455 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 4qmu | SKE | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.455 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.455 | |
| 5bmv | VLB | Tubulin alpha-1B chain | / | 0.455 | |
| 5bmv | VLB | Tubulin beta chain | / | 0.455 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.454 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.454 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.454 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.454 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.454 | |
| 4l8u | 9AZ | Serum albumin | / | 0.454 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.454 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.454 | |
| 5c8y | ACP | Tubulin tyrosine ligase | / | 0.454 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1err | RAL | Estrogen receptor | / | 0.453 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.453 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.453 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2fai | 459 | Estrogen receptor | / | 0.453 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.453 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.453 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.453 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.453 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.453 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.452 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.452 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.452 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.452 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.452 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.452 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.452 | |
| 2xvq | 9DS | Serum albumin | / | 0.452 | |
| 3bpt | QUE | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | 3.1.2.4 | 0.452 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3eem | 53V | Uncharacterized protein | / | 0.452 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.452 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.452 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.452 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.452 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.452 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.452 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.451 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.451 | |
| 2q7l | TES | Androgen receptor | / | 0.451 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.451 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.451 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.451 | |
| 4apu | A2K | Progesterone receptor | / | 0.451 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.451 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4jaq | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.451 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.451 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.451 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.451 | |
| 1eio | GCH | Gastrotropin | / | 0.450 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.450 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.450 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1xny | 191 | Propionyl-CoA carboxylase complex B subunit | / | 0.450 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.450 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2qpy | DHT | Androgen receptor | / | 0.450 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.450 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.450 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.450 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.450 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.450 | |
| 4hxy | NDP | Plm1 | / | 0.450 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.450 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.449 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2j7p | GNP | Signal recognition particle protein | / | 0.449 | |
| 2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.449 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.449 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.449 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.449 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.449 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3zuy | TCH | Transporter | / | 0.449 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.449 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.449 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.448 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 2piv | DHT | Androgen receptor | / | 0.448 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2ylq | TES | Androgen receptor | / | 0.448 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.448 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.448 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.448 | |
| 4l3j | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.448 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4q5h | ANP | Protein kinase OspG | 2.7 | 0.448 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.447 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.447 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2bxq | IMN | Serum albumin | / | 0.447 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.447 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.447 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.447 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.447 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.447 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.447 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4czt | CPS | CBL-interacting serine/threonine-protein kinase 23 | 2.7.11.1 | 0.447 | |
| 4f63 | 0S7 | Fibroblast growth factor receptor 1 | / | 0.447 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.447 | |
| 4l4x | NDP | AmphI | / | 0.447 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.447 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.447 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.447 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.446 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.446 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2wpw | ACO | Orf14 | / | 0.446 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.446 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.446 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.446 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.446 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.446 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.446 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1r6w | 164 | o-succinylbenzoate synthase | / | 0.445 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.445 | |
| 1t65 | DHT | Androgen receptor | / | 0.445 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.445 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.445 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.445 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.445 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.445 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 4iae | 1DX | Alr2278 protein | / | 0.445 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.445 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.445 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.445 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.445 | |
| 4okx | 198 | Androgen receptor | / | 0.445 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.444 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.444 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.444 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.444 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.444 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.444 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.444 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.444 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 4asj | N6A | Glucose-1-phosphate thymidylyltransferase | / | 0.444 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.444 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1oec | AA2 | Fibroblast growth factor receptor 2 | / | 0.443 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 1t09 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2fum | MIX | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.443 | |
| 2iog | IOG | Estrogen receptor | / | 0.443 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.443 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.443 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.443 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.443 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.443 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.443 | |
| 4l98 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.443 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.442 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.442 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 1y6b | AAX | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2p55 | MRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.442 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.442 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.442 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.442 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.442 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3tw6 | ADP | Pyruvate carboxylase | / | 0.442 | |
| 3zqt | TES | Androgen receptor | / | 0.442 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.442 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1e7a | PFL | Serum albumin | / | 0.441 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1mqb | ANP | Ephrin type-A receptor 2 | 2.7.10.1 | 0.441 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.441 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.441 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.441 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.441 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 2pir | DHT | Androgen receptor | / | 0.441 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.441 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.441 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.441 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.441 | |
| 3h1j | SMA | Cytochrome b | / | 0.441 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3p5k | P5K | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3r1y | X76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.441 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.441 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.441 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.441 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.441 | |
| 4bmp | FMN | Protein NrdI | / | 0.441 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4flp | JQ1 | Bromodomain testis-specific protein | / | 0.441 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 4j1r | I5R | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.441 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.441 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.441 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.440 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.440 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.440 | |
| 1zky | 689 | Estrogen receptor | / | 0.440 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.440 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2eau | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.440 | |
| 2lf1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2vgo | AD5 | Aurora kinase B-A | 2.7.11.1 | 0.440 | |
| 2x6d | X6D | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 3ckt | YDP | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3k9v | CPS | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | / | 0.440 | |
| 3p79 | P79 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.440 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.440 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.440 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4ie0 | PD2 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.440 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.440 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.440 | |
| 4l9q | 9TP | Serum albumin | / | 0.440 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.440 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.440 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.440 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.440 |