Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 1.000 | |
| 3iis | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.617 | |
| 2x21 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.614 | |
| 2x1z | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.555 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.520 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.514 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.510 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.509 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.504 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.503 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.502 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.501 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.499 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.498 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.498 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.497 | |
| 3reo | EUG | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.495 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.495 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.494 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.494 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.493 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.492 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.492 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.489 | |
| 5aaj | HSC | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.488 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.487 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.487 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.487 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.486 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.486 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.486 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.485 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.485 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.484 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.484 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.483 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.483 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.482 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.482 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.482 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.481 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.481 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.481 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.481 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.480 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.480 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.480 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.479 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.478 | |
| 3qly | 55V | Uncharacterized protein | / | 0.478 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.477 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.477 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.477 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.477 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.476 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.475 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.475 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.475 | |
| 3fu8 | 3DM | Laccase-1 | 1.10.3.2 | 0.475 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.475 | |
| 3x0a | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.475 | |
| 1ezv | SMA | Cytochrome b | / | 0.474 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.474 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 2xvw | 9NR | Serum albumin | / | 0.474 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.474 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.474 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.474 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.474 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.473 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.473 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 2gh6 | CF3 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.473 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.473 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.473 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.473 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.473 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.472 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.472 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.472 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.471 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.471 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.471 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.471 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.471 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.470 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.470 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.470 | |
| 1ohk | COP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.469 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.469 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.468 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3h18 | PMS | Esterase/lipase | / | 0.468 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.468 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.468 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.467 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.467 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.467 | |
| 4zas | TYD | CalS13 | / | 0.467 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1fcx | 184 | Retinoic acid receptor gamma | / | 0.466 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.466 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.466 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.465 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.465 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.465 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.465 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.465 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.464 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.464 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.464 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.463 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.463 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.463 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.463 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.462 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.462 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.462 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.462 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.461 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2y37 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.461 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.461 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.461 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.461 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.461 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.461 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.460 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.460 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.460 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.460 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.460 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.459 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.459 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.459 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.459 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.459 | |
| 4u95 | MIY | Multidrug efflux pump subunit AcrB | / | 0.459 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.458 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.458 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.458 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.458 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.458 | |
| 3cse | N22 | Uncharacterized protein | / | 0.458 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.457 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 2iog | IOG | Estrogen receptor | / | 0.457 | |
| 2lbd | REA | Retinoic acid receptor gamma | / | 0.457 | |
| 2puj | HPZ | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.457 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.457 | |
| 3cxh | SMA | Cytochrome b | / | 0.457 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3htj | ET | EbrA repressor | / | 0.457 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.457 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.457 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.457 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.456 | |
| 2xvv | 9DN | Serum albumin | / | 0.456 | |
| 3jrx | S1A | Acetyl-CoA carboxylase 2 | / | 0.456 | |
| 3nhw | ZXZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.456 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.456 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.456 | |
| 4l8u | 9AZ | Serum albumin | / | 0.456 | |
| 4n1g | CEI | Obelin | / | 0.456 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.456 | |
| 1dub | CAA | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.455 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.455 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.455 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.455 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.455 | |
| 3eej | 53R | Uncharacterized protein | / | 0.455 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.455 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 4ux6 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.455 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1m8h | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.454 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1syn | F89 | Thymidylate synthase | / | 0.454 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.454 | |
| 2g5o | DRQ | Estrogen receptor | / | 0.454 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.454 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.454 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.454 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.454 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.454 | |
| 3saz | 043 | Malate synthase G | / | 0.454 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.454 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.454 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.454 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 4o4e | ATP | Kinase | / | 0.454 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.453 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.453 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.453 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2ibz | SMA | Cytochrome b | / | 0.453 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.453 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 5cto | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.453 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.453 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.452 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.452 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.452 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.452 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.452 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.452 | |
| 3up0 | D7S | aceDAF-12 | / | 0.452 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.452 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.452 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.452 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4ifv | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.452 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.452 | |
| 5ahk | FAD | Acetolactate synthase II, large subunit | / | 0.452 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.451 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.451 | |
| 3dlg | GWE | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3q0g | COA | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.451 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.451 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.451 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.451 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.450 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.450 | |
| 1kb9 | SMA | Cytochrome b | / | 0.450 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.450 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.450 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.450 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.450 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.450 | |
| 3p9t | TCL | Repressor | / | 0.450 | |
| 3r43 | ID8 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4ax8 | ADP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.450 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 4fj0 | HHF | 17beta-hydroxysteroid dehydrogenase | / | 0.450 | |
| 4g1n | NZT | Pyruvate kinase PKM | 2.7.1.40 | 0.450 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.449 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 1vrq | FON | Subunit alpha of sarocosine oxidase | / | 0.449 | |
| 2jj1 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 2jj1 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.449 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.449 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.449 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.449 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.449 | |
| 3t9i | 3T9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.449 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.449 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.449 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.448 | |
| 1exa | 394 | Retinoic acid receptor gamma | / | 0.448 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1sqq | OST | Cytochrome b | / | 0.448 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2apg | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.448 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2p15 | EZT | Estrogen receptor | / | 0.448 | |
| 2rab | NAD | Glutathione amide reductase | / | 0.448 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.448 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.448 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3up3 | XCA | aceDAF-12 | / | 0.448 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.448 | |
| 4a99 | MIY | TetX family tetracycline inactivation enzyme | / | 0.448 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.448 | |
| 4y0k | NAP | AntE | / | 0.448 | |
| 5bsr | COA | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.448 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.447 | |
| 1kyo | SMA | Cytochrome b | / | 0.447 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.447 | |
| 2bxm | IMN | Serum albumin | / | 0.447 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.447 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 3eel | 53T | Uncharacterized protein | / | 0.447 | |
| 3nhk | VAP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.447 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.447 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.446 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.446 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.446 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 2rht | C1E | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.446 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.446 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.446 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.446 | |
| 4fvx | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.446 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.445 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.445 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1z1f | STL | Resveratrol synthase | / | 0.445 | |
| 2b5j | 3AC | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.445 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.445 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.445 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.445 | |
| 3nwe | 662 | Catechol O-methyltransferase | 2.1.1.6 | 0.445 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.445 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.445 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.444 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.444 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3bjh | NBB | Odorant binding protein ASP1 | / | 0.444 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.444 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.444 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.444 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.444 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.444 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3nod | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.444 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.444 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.444 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.444 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.444 | |
| 4xwt | U5P | Ribonuclease J | / | 0.444 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1klm | SPP | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.443 | |
| 1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.443 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.443 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 2jkc | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.443 | |
| 2yat | EEU | Estrogen receptor | / | 0.443 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3ipt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.443 | |
| 3jt8 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.443 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3svp | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.443 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.443 | |
| 4k5d | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4mr4 | 1K0 | Bromodomain-containing protein 4 | / | 0.443 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.443 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.443 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.442 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1m8i | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.442 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.442 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3acy | 702 | Dehydrosqualene synthase | / | 0.442 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.442 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.442 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.442 | |
| 4b0j | 3MQ | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.442 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.442 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.442 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1m8d | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.441 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.441 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.441 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.441 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2mm3 | CHO | Gastrotropin | / | 0.441 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.441 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3nhf | VVV | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3rql | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.441 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.441 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.441 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.441 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1k2s | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.440 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 2bzs | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.440 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.440 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.440 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.440 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.440 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 4aql | TXC | Guanine deaminase | 3.5.4.3 | 0.440 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.440 | |
| 4fj2 | QSO | 17beta-hydroxysteroid dehydrogenase | / | 0.440 | |
| 5bp7 | SAH | SAM-dependent methyltransferase | / | 0.440 |