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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1th8ADPAnti-sigma F factor

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1th8ADPAnti-sigma F factor/1.000
1thnADPAnti-sigma F factor/0.631
1i59ANPChemotaxis protein CheA2.7.13.30.582
1tilATPAnti-sigma F factor/0.547
1i58ADPChemotaxis protein CheA2.7.13.30.546
1i59ADPChemotaxis protein CheA2.7.13.30.545
1i5aACPChemotaxis protein CheA2.7.13.30.531
1i58ACPChemotaxis protein CheA2.7.13.30.515
2zkjADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.512
4xivACPChemotaxis protein CheA2.7.13.30.508
4r3aANPBlue-light-activated histidine kinase 22.7.13.30.506
4r39ANPBlue-light-activated histidine kinase 22.7.13.30.502
4xivADPChemotaxis protein CheA2.7.13.30.500
1nhhANPDNA mismatch repair protein MutL/0.495
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.495
1mx0ANPType 2 DNA topoisomerase 6 subunit B/0.494
4h1e10JBeta-secretase 13.4.23.460.494
2iorADPChaperone protein HtpG/0.491
3thrC2FGlycine N-methyltransferase2.1.1.200.488
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.487
3tkyN7I(Iso)eugenol O-methyltransferase2.1.1.1460.486
4h3g10QBeta-secretase 13.4.23.460.485
4h3j10WBeta-secretase 13.4.23.460.485
4asf62UATP-dependent molecular chaperone HSP82/0.483
1t4v14AProthrombin3.4.21.50.481
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.479
1lb9DNQGlutamate receptor 2/0.478
2ban357Gag-Pol polyprotein2.7.7.490.478
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.478
2uz1TPPBenzaldehyde lyase/0.477
1lkdBP6Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.476
1z59ADPType 2 DNA topoisomerase 6 subunit B/0.476
2pauD5M5'-deoxynucleotidase YfbR/0.476
4gk3L87Ephrin type-A receptor 32.7.10.10.476
4z1fH71Heat shock protein 75 kDa, mitochondrial/0.476
1m78NDPDihydrofolate reductase1.5.1.30.475
2bu8ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.475
1am1ADPATP-dependent molecular chaperone HSP82/0.474
1dr3TAPDihydrofolate reductase1.5.1.30.472
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.472
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.472
4ivd15TTyrosine-protein kinase JAK1/0.472
1d6w00RProthrombin3.4.21.50.471
3rlr3RRHeat shock protein HSP 90-alpha/0.471
3zewSTUEphrin type-B receptor 42.7.10.10.471
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.471
1kceCB3Thymidylate synthase/0.470
2ejzSAHDiphthine synthase/0.470
3s7a684Dihydrofolate reductase1.5.1.30.470
4dju0KKBeta-secretase 13.4.23.460.470
4g8cC6LAlpha/beta hydrolase fold protein/0.470
4gk2L66Ephrin type-A receptor 32.7.10.10.470
1kzjCB3Thymidylate synthase/0.469
1mvsDTMDihydrofolate reductase1.5.1.30.469
2fypRDEEndoplasmin/0.469
4ixgIXGDihydrofolate reductase1.5.1.30.469
3wv7ADPHmd co-occurring protein HcgE/0.468
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.468
5cc9DDFDihydrofolate reductase1.5.1.30.468
2bu2ATP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.467
2ykcYKCHeat shock protein HSP 90-alpha/0.467
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.467
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4c717RD3-oxoacyl-ACP synthase/0.466
3qakUKAAdenosine receptor A2a/0.466
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.465
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.465
1db1VDXVitamin D3 receptor/0.464
3nga3NGCasein kinase II subunit alpha2.7.11.10.464
5k2dZMAAdenosine receptor A2a/0.464
1byqADPHeat shock protein HSP 90-alpha/0.463
1dr3HBIDihydrofolate reductase1.5.1.30.463
1s3uTQDDihydrofolate reductase1.5.1.30.463
2bbqPFGThymidylate synthase/0.463
2v1aFMNNPH1-1/0.463
3r4pFU7Heat shock protein HSP 90-alpha/0.463
3d2rADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.462
3hz142CHeat shock protein HSP 90-alpha/0.462
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.462
3mauPLRPutative sphingosine-1-phosphate lyase/0.462
1ay0TPPTransketolase 12.2.1.10.461
2bu9HFVIsopenicillin N synthase1.21.3.10.461
3c11GDMATP-dependent molecular chaperone HSP82/0.461
3wv9FEGHmd co-occurring protein HcgE/0.461
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4jqlVJ6Heat shock protein HSP 90-alpha/0.461
4xclAGSHeat shock cognate 90 kDa protein/0.461
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.460
1xzqFONtRNA modification GTPase MnmE3.6.50.460
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.460
2xx213CATP-dependent molecular chaperone HSP82/0.460
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.460
3v49PK0Androgen receptor/0.460
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
5e92ANPTGF-beta receptor type-22.7.11.300.460
1dliUDXUDP-glucose 6-dehydrogenase/0.459
1klkPMDDihydrofolate reductase1.5.1.30.459
3hk1B64Fatty acid-binding protein, adipocyte/0.459
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.459
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.459
5iu86DZAdenosine receptor A2a/0.459
1pd9CO4Dihydrofolate reductase1.5.1.30.458
4bqjXKLHeat shock protein HSP 90-alpha/0.458
4iteTEYVitamin D3 receptor/0.458
1ao8MTXDihydrofolate reductase1.5.1.30.457
1jpaANPEphrin type-B receptor 22.7.10.10.457
1yetGDMHeat shock protein HSP 90-alpha/0.457
1yplRA8Prothrombin3.4.21.50.457
3bw4FMNPutative 2-nitropropane dioxygenase/0.457
3nmpPYVAbscisic acid receptor PYL2/0.457
4fcr0TMHeat shock protein HSP 90-alpha/0.457
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.457
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.457
1itzTPPTransketolase, chloroplastic2.2.1.10.456
1swtBTNStreptavidin/0.456
1zgv501Prothrombin3.4.21.50.456
3d74NBBPheromone-binding protein ASP1/0.456
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.456
3qgi33FGenome polyprotein2.7.7.480.456
4eh5IRGMitogen-activated protein kinase 14/0.456
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.456
1ftlDNQGlutamate receptor 2/0.455
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
3biy01KHistone acetyltransferase p300/0.455
3hz137DHeat shock protein HSP 90-alpha/0.455
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.455
3w0hW12Vitamin D3 receptor/0.455
4b8uIBK3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase4.2.1.590.455
4h3i10VBeta-secretase 13.4.23.460.455
1lbbKAIGlutamate receptor 2/0.454
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.454
2ea1GPGRibonuclease I3.1.27.60.454
2w9hTOPDihydrofolate reductase1.5.1.30.454
3aw9GDUNAD-dependent epimerase/dehydratase/0.454
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.454
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.454
3vv8B02Beta-secretase 13.4.23.460.454
4b63NAPL-ornithine N(5)-monooxygenase/0.454
4egnTWOCytochrome P450/0.454
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.454
1d3dBZTProthrombin3.4.21.50.453
1synF89Thymidylate synthase/0.453
1t4u81AProthrombin3.4.21.50.453
1xm1GAHProthrombin3.4.21.50.453
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.453
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.453
2xhrC0PHeat shock protein HSP 90-alpha/0.453
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.452
1dajMOTDihydrofolate reductase1.5.1.30.452
2ekaSAHDiphthine synthase/0.452
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.452
2jh6894Prothrombin3.4.21.50.452
2xyuQ9GEphrin type-A receptor 42.7.10.10.452
3ft8MOJHeat shock protein HSP 90-alpha/0.452
3qzyFADFAD-linked sulfhydryl oxidase/0.452
4djy0KRBeta-secretase 13.4.23.460.452
4fhd0TTSpore photoproduct lyase/0.452
4friDWABeta-secretase 13.4.23.460.452
4m6jNDPDihydrofolate reductase1.5.1.30.452
5fliQUEQuercetinase QueD/0.452
1opbRETRetinol-binding protein 2/0.451
2wo7ASVIsopenicillin N synthase1.21.3.10.451
2yegXQGHeat shock protein HSP 90-alpha/0.451
3c36KAIGlutamate receptor ionotropic, kainate 1/0.451
3dogNNNCyclin-dependent kinase 22.7.11.220.451
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.451
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.451
4jpe1M7Beta-secretase 13.4.23.460.451
1oc1ASVIsopenicillin N synthase1.21.3.10.450
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.450
1tdrMTXDihydrofolate reductase1.5.1.30.450
1tl3H20Gag-Pol polyprotein2.7.7.490.450
2iviACWIsopenicillin N synthase1.21.3.10.450
2xw7NDPDihydrofolate reductase/0.450
3a1l2CCCytochrome P450/0.450
4a16H34Acetylcholinesterase3.1.1.70.450
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.450
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4fod0UVALK tyrosine kinase receptor2.7.10.10.450
4jlm1NNDeoxycytidine kinase2.7.1.740.450
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
4mv4ACPBiotin carboxylase6.3.4.140.450
4tyj0LIFibroblast growth factor receptor 42.7.10.10.450
5k7wSAHN6-adenosine-methyltransferase 70 kDa subunit/0.450
5uviZMAAdenosine receptor A2a/0.450
5jtbZMAAdenosine receptor A2a/0.450
3uzcT4EAdenosine receptor A2a/0.450
1blzACVIsopenicillin N synthase1.21.3.10.449
1jomFFODihydrofolate reductase1.5.1.30.449
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.449
1u1d181Uridine phosphorylase2.4.2.30.449
2in6839Wee1-like protein kinase2.7.10.20.449
2wm3NFLNmrA-like family domain-containing protein 1/0.449
2ykeYKEHeat shock protein HSP 90-alpha/0.449
2zhf49UProthrombin3.4.21.50.449
3co93MSGenome polyprotein2.7.7.480.449
3djfBC3Purine nucleoside phosphorylase/0.449
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3oiaA31Camphor 5-monooxygenase1.14.15.10.449
3zw9T1GPeroxisomal bifunctional enzyme1.1.1.350.449
4ce2BO5ATP-dependent molecular chaperone HSP82/0.449
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4j6dTESCytochrome P450 monooxygenase/0.449
5iubCLRAdenosine receptor A2a/0.449
1a8rGTPGTP cyclohydrolase 13.5.4.160.448
1mvtDTMDihydrofolate reductase1.5.1.30.448
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.448
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2q8iRDC[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial2.7.11.20.448
2wi5ZZ5Heat shock protein HSP 90-alpha/0.448
2wipP49Cyclin-dependent kinase 22.7.11.220.448
2y6fM9FIsopenicillin N synthase1.21.3.10.448
2z4y252Geranylgeranyl pyrophosphate synthase/0.448
4eiyZMAAdenosine receptor A2a/0.448
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.448
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
1dr5NAPDihydrofolate reductase1.5.1.30.447
1ie9VDXVitamin D3 receptor/0.447
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.447
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
2aclREARetinoic acid receptor RXR-alpha/0.447
2bunFADAppA protein/0.447
2gjlFMNNitronate monooxygenase1.13.12.160.447
2gqpPA7Endoplasmin/0.447
2nnlERDDihydroflavonol 4-reductase1.1.1.2190.447
3cgdCOACoenzyme A disulfide reductase/0.447
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.447
3qj0QI3Botulinum neurotoxin type A3.4.24.690.447
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.447
3r8gIZPAldo-keto reductase family 1 member C3/0.447
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.447
4a9e3PFBromodomain-containing protein 2/0.447
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.447
4o74R78Bromodomain-containing protein 4/0.447
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.447
5dp2NAPCurF/0.447
1e79ATPATP synthase subunit alpha, mitochondrial/0.446
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.446
1ia1NDPDihydrofolate reductase1.5.1.30.446
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
1vruAAPGag-Pol polyprotein2.7.7.490.446
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.446
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.446
2dhfDZFDihydrofolate reductase1.5.1.30.446
2gjnFMNNitronate monooxygenase1.13.12.160.446
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
2puiADPMethylthioribose kinase2.7.1.1000.446
2vcmM11Isopenicillin N synthase1.21.3.10.446
3c34KAIGlutamate receptor ionotropic, kainate 1/0.446
4a7b3W4Collagenase 33.4.240.446
4twnB96Ephrin type-A receptor 32.7.10.10.446
4udcDEXGlucocorticoid receptor/0.446
1ei1ANPDNA gyrase subunit B/0.445
1fxfMJIPhospholipase A2, major isoenzyme3.1.1.40.445
1hb1OCVIsopenicillin N synthase1.21.3.10.445
1tkzH16Gag-Pol polyprotein2.7.7.490.445
1u71MXADihydrofolate reductase1.5.1.30.445
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.445
2xk2ADPHeat shock protein HSP 90-alpha/0.445
2xpuTDCTetracycline repressor protein class D/0.445
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.445
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3ko8NADNAD-dependent epimerase/dehydratase/0.445
3rtnRTNBeta-secretase 13.4.23.460.445
3ssoSAHMycinamicin VI 2''-O-methyltransferase/0.445
3wznBTNStreptavidin/0.445
4a86H35Major pollen allergen Bet v 1-A/0.445
4frjDWBBeta-secretase 13.4.23.460.445
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4kwhNAPReductase homolog/0.445
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.445
1axwMTXThymidylate synthase/0.444
1booSAHModification methylase PvuII2.1.1.1130.444
1dhrNADDihydropteridine reductase1.5.1.340.444
1kl2FONSerine hydroxymethyltransferase/0.444
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.444
1s1wUC1Gag-Pol polyprotein2.7.7.490.444
1tduDURThymidylate synthase/0.444
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.444
2bjsACVIsopenicillin N synthase1.21.3.10.444
2byi2DDHeat shock protein HSP 90-alpha/0.444
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
2ek3SAHDiphthine synthase/0.444
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.444
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.444
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.444
2pg0FADAcyl-CoA dehydrogenase/0.444
2vnkFADNADPH:ferredoxin reductase/0.444
2zfq45UProthrombin3.4.21.50.444
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.444
3akzGSUGlutamate--tRNA ligase 2/0.444
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
3phiNDPShikimate dehydrogenase (NADP(+))/0.444
4b0qGMFBeta-secretase 13.4.23.460.444
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.444
4ewhT77Activated CDC42 kinase 1/0.444
4ia7BIVVitamin D3 receptor A/0.444
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.444
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
5iu4ZMAAdenosine receptor A2a/0.444
1i5cADPChemotaxis protein CheA2.7.13.30.443
1trgCB3Thymidylate synthase/0.443
1uy9PU6Heat shock protein HSP 90-alpha/0.443
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2b7aIZATyrosine-protein kinase JAK2/0.443
2egsSAHDiphthine synthase/0.443
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.443
2opqHBQGag-Pol polyprotein2.7.7.490.443
2v3wTPPBenzoylformate decarboxylase4.1.1.70.443
2wepADPATP-dependent molecular chaperone HSP82/0.443
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3ekrPY9Heat shock protein HSP 90-alpha/0.443
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.443
3gieACPSensor histidine kinase DesK2.7.13.30.443
3hz6ADPXylulokinase/0.443
3pxkPXKFocal adhesion kinase 12.7.10.20.443
4b0532DBeta-secretase 13.4.23.460.443
4b78KGGBeta-secretase 13.4.23.460.443
4dh60KNBeta-secretase 13.4.23.460.443
4ead0NPThymidine phosphorylase2.4.2.40.443
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4iaq2GM5-hydroxytryptamine receptor 1B/0.443
4iyg1HUStrictosidine synthase4.3.3.20.443
4ng4ADPPhosphoglycerate kinase/0.443
4xnw2IDP2Y purinoceptor 1/0.443
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.442
1fw0KAIGlutamate receptor 2/0.442
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.442
1lgtBP3Biphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.442
1mu6CDAProthrombin3.4.21.50.442
1pzhNADLactate dehydrogenase/0.442
1uyiPUZHeat shock protein HSP 90-alpha/0.442
2fzhDH1Dihydrofolate reductase1.5.1.30.442
2xabVHDHeat shock protein HSP 90-alpha/0.442
2zlcVDXVitamin D3 receptor/0.442
3elySAHMethyltransferase/0.442
3g0fB49Mast/stem cell growth factor receptor Kit2.7.10.10.442
3iedAN2HSP90/0.442
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.442
3t10ACPHeat shock protein HSP 90-alpha/0.442
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.442
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
4m6l21VDihydrofolate reductase1.5.1.30.442
4p6wMOFGlucocorticoid receptor/0.442
4uyf73BBromodomain-containing protein 2/0.442
4x5fFOLDihydrofolate reductase1.5.1.30.442
4xbfFADLysine-specific histone demethylase 1A10.442
5iua6DXAdenosine receptor A2a/0.442
3emlZMAAdenosine receptor A2a/0.442
1gky5GPGuanylate kinase2.7.4.80.441
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.441
1rdtL79Retinoic acid receptor RXR-alpha/0.441
1rfqLARActin, alpha skeletal muscle/0.441
1u2rSO1Elongation factor 2/0.441
1yqzCOACoenzyme A disulfide reductase/0.441
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.441
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.441
2hamC33Vitamin D3 receptor/0.441
2r6jNDPEugenol synthase 11.1.1.3180.441
2w6qOA5Biotin carboxylase6.3.4.140.441
2xx413IATP-dependent molecular chaperone HSP82/0.441
3ed1GA3Gibberellin receptor GID1/0.441
3maaFKPAdenylate cyclase type 2/0.441
3maaFKPAdenylate cyclase type 5/0.441
3owj1ELCasein kinase II subunit alpha2.7.11.10.441
3pqbVGPPutative oxidoreductase/0.441
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
3zknWZVBeta-secretase 23.4.23.450.441
4c66H4CBromodomain-containing protein 4/0.441
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4kjjFOLDihydrofolate reductase1.5.1.30.441
4li81XQTankyrase-12.4.2.300.441
4lsjLSJGlucocorticoid receptor/0.441
4xc0ACPHeat shock cognate 90 kDa protein/0.441
5k2aZMAAdenosine receptor A2a/0.441
1h74ADPHomoserine kinase2.7.1.390.440
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
1nm6L86Prothrombin3.4.21.50.440
1x8b824Wee1-like protein kinase2.7.10.20.440
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2h55DZ8Heat shock protein HSP 90-alpha/0.440
2qvy34Z4-chlorobenzoyl CoA ligase/0.440
2rhrEMOPutative ketoacyl reductase1.3.10.440
2w02ATPAcsD/0.440
2xcmADPCytosolic heat shock protein 90/0.440
2y5s78HDihydropteroate synthase/0.440
3eblGA4Gibberellin receptor GID1/0.440
3havATPAminoglycoside phosphotransferase/0.440
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.440
3k47D09Dihydrofolate reductase1.5.1.30.440
3q5kD1UHeat shock protein 83-1/0.440
3qwc98PProthrombin3.4.21.50.440
3uptTPPTransketolase/0.440
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
4b1fKRHGlutamate racemase/0.440
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4h6rFDAProline dehydrogenase/0.440
5k2cZMAAdenosine receptor A2a/0.440