sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 1.000 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.509 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.499 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.489 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.486 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.486 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.485 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.485 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.484 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.484 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.484 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.484 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.483 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 5dp2 | NAP | CurF | / | 0.482 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 4ubu | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.481 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.478 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.478 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.477 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.477 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.475 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.475 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.475 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.475 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.472 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.472 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.470 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.470 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.469 | |
| 4irn | FAD | AnaB | / | 0.468 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.468 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.467 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.467 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.467 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3v2u | ATP | Protein GAL3 | / | 0.467 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.467 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.466 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.465 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.465 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.465 | |
| 5f12 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.465 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.464 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.464 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.464 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.464 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.463 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.463 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.463 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.462 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.462 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.461 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.461 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.461 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.461 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.461 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.460 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.460 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.460 | |
| 3up0 | D7S | aceDAF-12 | / | 0.460 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.460 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.459 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.459 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 3eku | CY9 | Actin-5C | / | 0.459 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.459 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.459 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.458 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.458 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.458 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.458 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.458 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.457 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.457 | |
| 4l4x | NDP | AmphI | / | 0.457 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.456 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.456 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.456 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.455 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.455 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.455 | |
| 3gwd | NAP | Cyclohexanone monooxygenase | / | 0.455 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.455 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.454 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.454 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.454 | |
| 1ndi | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.453 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1tys | DHF | Thymidylate synthase | / | 0.453 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.453 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.453 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.453 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.453 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.452 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.452 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.452 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.452 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4fxf | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.452 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.452 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.452 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.452 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.451 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.451 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.451 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 1gqt | ACP | Ribokinase | / | 0.450 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.450 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.450 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.450 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.450 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.450 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.450 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.449 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.449 | |
| 2quj | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.449 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.449 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.449 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.448 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.448 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.448 | |
| 3suf | SUE | Polyprotein | / | 0.448 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.447 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.447 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.447 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.447 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.447 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3kry | 3KR | Collagenase 3 | 3.4.24 | 0.447 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.447 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.447 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.447 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.447 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.447 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.447 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.447 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.446 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.446 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.446 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.446 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.446 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.446 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.446 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.446 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.445 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.445 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.445 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.445 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.445 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.445 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.445 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.445 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.445 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.444 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.444 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.444 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.444 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.444 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.444 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.444 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.444 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.443 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.443 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.443 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.443 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.443 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.443 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.443 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.443 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 4frs | 0V6 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4rx6 | ATP | Nitrogen regulatory PII-like protein | / | 0.443 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.443 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.443 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.442 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.442 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2y3r | TRK | TamL | / | 0.442 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.442 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3l5e | BDW | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.442 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.442 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.442 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.442 | |
| 4xr9 | NAD | CalS8 | / | 0.442 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.441 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 2y4g | TIR | TamL | / | 0.441 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.441 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.441 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 5ej4 | TD6 | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.440 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.440 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.440 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.440 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.440 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.440 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.440 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.440 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.440 |