Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4cj5 | 4VW | Integrase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4cj5 | 4VW | Integrase | / | 1.000 | |
| 4cje | Q31 | Integrase | / | 0.670 | |
| 4cj3 | E4F | Integrase | / | 0.660 | |
| 3zsw | ZSW | Integrase | / | 0.651 | |
| 4cjq | VXO | Integrase | / | 0.647 | |
| 4cgh | LOZ | Integrase | / | 0.628 | |
| 4cf2 | 3GM | Integrase | / | 0.627 | |
| 4cfa | WOP | Integrase | / | 0.627 | |
| 4cgd | 8P3 | Integrase | / | 0.619 | |
| 4cgg | K5Q | Integrase | / | 0.618 | |
| 4cf0 | O5U | Integrase | / | 0.616 | |
| 4cea | ZSW | Integrase | / | 0.615 | |
| 4cef | D0T | Integrase | / | 0.614 | |
| 4cgj | NZL | Integrase | / | 0.609 | |
| 4cer | VL4 | Integrase | / | 0.607 | |
| 4ces | NFW | Integrase | / | 0.607 | |
| 4cjp | 4D2 | Integrase | / | 0.606 | |
| 3zsy | OM3 | Integrase | / | 0.604 | |
| 4cfb | OM3 | Integrase | / | 0.602 | |
| 4cfc | 7NV | Integrase | / | 0.600 | |
| 4cgi | NZL | Integrase | / | 0.599 | |
| 4cfd | S8Y | Integrase | / | 0.595 | |
| 4ceq | QCH | Integrase | / | 0.594 | |
| 4cif | JDX | Integrase | / | 0.593 | |
| 4cjk | H39 | Integrase | / | 0.592 | |
| 4cjr | FYM | Integrase | / | 0.589 | |
| 4cig | X0P | Integrase | / | 0.588 | |
| 4ck3 | K1T | Integrase | / | 0.586 | |
| 4cjf | RVN | Integrase | / | 0.585 | |
| 4cjs | L0Y | Integrase | / | 0.585 | |
| 3zsr | O3N | Integrase | / | 0.584 | |
| 4cez | O3N | Integrase | / | 0.584 | |
| 4ck2 | NVU | Integrase | / | 0.579 | |
| 3zsv | ZSV | Integrase | / | 0.574 | |
| 4ceb | ZSV | Integrase | / | 0.574 | |
| 4ced | 9NS | Integrase | / | 0.573 | |
| 3zt0 | ZT0 | Integrase | / | 0.572 | |
| 4cf8 | V7H | Integrase | / | 0.570 | |
| 4ce9 | O3N | Integrase | / | 0.569 | |
| 3zcm | PX3 | Integrase | / | 0.568 | |
| 4ck1 | OM1 | Integrase | / | 0.568 | |
| 3zsq | O4N | Integrase | / | 0.563 | |
| 3zt3 | ZT4 | Integrase | / | 0.559 | |
| 4ceo | G0T | Integrase | / | 0.556 | |
| 4chy | C5Q | Integrase | / | 0.554 | |
| 4cju | JNS | Integrase | / | 0.554 | |
| 4cec | 2SS | Integrase | / | 0.550 | |
| 4cj4 | S3G | Integrase | / | 0.550 | |
| 3zsz | OM2 | Integrase | / | 0.549 | |
| 4cie | Y7N | Integrase | / | 0.547 | |
| 4chq | CWU | Integrase | / | 0.546 | |
| 4cee | B0T | Integrase | / | 0.545 | |
| 4cf1 | IY7 | Integrase | / | 0.541 | |
| 3zt2 | ZT2 | Integrase | / | 0.538 | |
| 3zt1 | OM1 | Integrase | / | 0.517 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.516 | |
| 3zsx | N44 | Integrase | / | 0.504 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.500 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.496 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.491 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.491 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.489 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.488 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.485 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.485 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.483 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.483 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.481 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.480 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.479 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.479 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.479 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.478 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.478 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.477 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.476 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.475 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.474 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.474 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.473 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.473 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.473 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 2ele | SAH | Diphthine synthase | / | 0.471 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.471 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.471 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.471 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.471 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.470 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.469 | |
| 2pvj | P44 | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.469 | |
| 1ywn | LIF | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.468 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.468 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.468 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.467 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.467 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.467 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.467 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3up0 | D7S | aceDAF-12 | / | 0.466 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.466 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.465 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.465 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.464 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.464 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.463 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.463 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.463 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.463 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.463 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.463 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.462 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.462 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.462 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.462 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3c16 | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 3c16 | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.461 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.461 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.461 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.461 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.461 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.461 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.461 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.461 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 2e9p | 77A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2j4k | U5P | Uridylate kinase | 2.7.4.22 | 0.460 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4aw0 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.460 | |
| 4ftq | 4HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.460 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.459 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.459 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.458 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.458 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.458 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.458 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3u9e | COA | Lmo1369 protein | / | 0.458 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.458 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.458 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.457 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.457 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.457 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.457 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2w6n | OA2 | Biotin carboxylase | 6.3.4.14 | 0.456 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.456 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.456 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.455 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.455 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1z1f | STL | Resveratrol synthase | / | 0.455 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.455 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.455 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.455 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.455 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.455 | |
| 1mrx | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.454 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.454 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.454 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.454 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3sa8 | K83 | Protease | / | 0.454 | |
| 3tti | KBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.454 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.454 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.454 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.454 | |
| 4ozn | ATP | Ammonium transporter | / | 0.454 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 5dmz | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.454 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.454 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.453 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2e8r | SAH | Diphthine synthase | / | 0.453 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.453 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.453 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.453 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.453 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.453 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.453 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.453 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.453 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.452 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.452 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.452 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.452 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.452 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3sac | AF8 | Protease | / | 0.452 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.452 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.452 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.452 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.451 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.451 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2j9m | PY8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.451 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.451 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3ag9 | A02 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 3fr8 | NDP | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.451 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.451 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.451 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.451 | |
| 3zuy | TCH | Transporter | / | 0.451 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.451 | |
| 4cgf | UJ6 | Integrase | / | 0.451 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.451 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.451 | |
| 1dcy | I3N | Phospholipase A2, membrane associated | / | 0.450 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.450 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.450 | |
| 3b9l | AZZ | Serum albumin | / | 0.450 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.450 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.450 | |
| 3em4 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.450 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.450 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.450 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.450 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.449 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.449 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.449 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 2i0a | MUI | Protease | / | 0.449 | |
| 2qln | F59 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.449 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3lfs | A07 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4b1f | KRH | Glutamate racemase | / | 0.449 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.449 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.448 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.448 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.448 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2qnp | QN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.448 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.448 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.448 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3vqu | O22 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.448 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 4l4x | NDP | AmphI | / | 0.448 | |
| 4m6p | 20R | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.448 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 4rqk | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 1eio | GCH | Gastrotropin | / | 0.447 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.447 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.447 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.447 | |
| 3dei | RXB | Caspase-3 | 3.4.22.56 | 0.447 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.447 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.447 | |
| 5ifi | PRX | Acetyl-coenzyme A synthetase | / | 0.447 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.446 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.446 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.446 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.446 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.446 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.446 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.446 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3so9 | 017 | Pol protein | / | 0.446 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.446 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.446 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.445 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 1vce | SAH | Diphthine synthase | / | 0.445 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.445 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 2r1r | TTP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.445 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2ym7 | YM7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.445 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3fly | FLY | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.445 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.445 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3qcq | 3Q0 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3qfv | NM7 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.445 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.445 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.445 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.445 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.445 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.445 | |
| 5ax3 | 5ID | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 5hyn | SAH | Histone-lysine N-methyltransferase EZH2 | 2.1.1.43 | 0.445 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.444 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.444 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1q3e | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.444 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.444 | |
| 1snu | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.444 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.444 | |
| 2biy | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2p2j | PRX | Acetyl-coenzyme A synthetase | / | 0.444 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.444 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2xvu | 9DN | Serum albumin | / | 0.444 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2ydj | YDJ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.444 | |
| 3nbv | ANP | Ketohexokinase | / | 0.444 | |
| 3orm | AGS | Serine/threonine protein kinase | / | 0.444 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3qrs | NK8 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3qwk | X62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.444 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.444 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.444 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.444 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bqr | IBH | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.444 | |
| 4trj | 665 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.444 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.444 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.444 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.443 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1msn | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.443 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.443 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2xvw | 9NR | Serum albumin | / | 0.443 | |
| 2y3s | TIR | TamL | / | 0.443 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.443 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4erk | OLO | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1agw | SU2 | Fibroblast growth factor receptor 1 | / | 0.442 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.442 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.442 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.442 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.442 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.442 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.442 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.442 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.442 | |
| 2xhx | T5M | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.442 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 3lcd | BDY | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.442 | |
| 3qcs | 3Q1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.442 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 4fta | H5K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.442 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.442 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1bv7 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.441 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1gqt | ACP | Ribokinase | / | 0.441 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.441 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1osv | CHC | Bile acid receptor | / | 0.441 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.441 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 1rw8 | 580 | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 1ung | ALH | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.441 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.441 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.441 | |
| 2i4x | KGQ | Protease | / | 0.441 | |
| 2pcg | SAH | Diphthine synthase | / | 0.441 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
| 2yi7 | BZ8 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.441 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.441 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3nxe | 2NC | Protease | / | 0.441 | |
| 3q5d | GDP | Atlastin-1 | 3.6.5 | 0.441 | |
| 3ql8 | X01 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3qn8 | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.441 | |
| 4ajn | 88V | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 4iak | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.441 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.441 | |
| 4jnm | 1LJ | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 4kin | 1M8 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.441 | |
| 4oey | DHT | Androgen receptor | / | 0.441 | |
| 4oty | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.441 | |
| 5d4v | SAH | Uncharacterized protein MJ0489 | / | 0.441 | |
| 5dr2 | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.440 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.440 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1r2j | FAD | FkbI | / | 0.440 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.440 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.440 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 2fna | ADP | Uncharacterized protein | / | 0.440 | |
| 2j5s | KTA | Alr4455 protein | / | 0.440 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.440 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3d57 | 4HY | Thyroid hormone receptor beta | / | 0.440 | |
| 3d76 | NBB | Pheromone-binding protein ASP1 | / | 0.440 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.440 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.440 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.440 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.440 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3nu3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.440 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4apu | OR8 | Progesterone receptor | / | 0.440 | |
| 4awi | AQ2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.440 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4fyn | 0VE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4iay | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.440 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.440 | |
| 4kbk | 1QG | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.440 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.440 |