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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4cj54VWIntegrase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4cj54VWIntegrase/1.000
4cjeQ31Integrase/0.670
4cj3E4FIntegrase/0.660
3zswZSWIntegrase/0.651
4cjqVXOIntegrase/0.647
4cghLOZIntegrase/0.628
4cf23GMIntegrase/0.627
4cfaWOPIntegrase/0.627
4cgd8P3Integrase/0.619
4cggK5QIntegrase/0.618
4cf0O5UIntegrase/0.616
4ceaZSWIntegrase/0.615
4cefD0TIntegrase/0.614
4cgjNZLIntegrase/0.609
4cerVL4Integrase/0.607
4cesNFWIntegrase/0.607
4cjp4D2Integrase/0.606
3zsyOM3Integrase/0.604
4cfbOM3Integrase/0.602
4cfc7NVIntegrase/0.600
4cgiNZLIntegrase/0.599
4cfdS8YIntegrase/0.595
4ceqQCHIntegrase/0.594
4cifJDXIntegrase/0.593
4cjkH39Integrase/0.592
4cjrFYMIntegrase/0.589
4cigX0PIntegrase/0.588
4ck3K1TIntegrase/0.586
4cjfRVNIntegrase/0.585
4cjsL0YIntegrase/0.585
3zsrO3NIntegrase/0.584
4cezO3NIntegrase/0.584
4ck2NVUIntegrase/0.579
3zsvZSVIntegrase/0.574
4cebZSVIntegrase/0.574
4ced9NSIntegrase/0.573
3zt0ZT0Integrase/0.572
4cf8V7HIntegrase/0.570
4ce9O3NIntegrase/0.569
3zcmPX3Integrase/0.568
4ck1OM1Integrase/0.568
3zsqO4NIntegrase/0.563
3zt3ZT4Integrase/0.559
4ceoG0TIntegrase/0.556
4chyC5QIntegrase/0.554
4cjuJNSIntegrase/0.554
4cec2SSIntegrase/0.550
4cj4S3GIntegrase/0.550
3zszOM2Integrase/0.549
4cieY7NIntegrase/0.547
4chqCWUIntegrase/0.546
4ceeB0TIntegrase/0.545
4cf1IY7Integrase/0.541
3zt2ZT2Integrase/0.538
3zt1OM1Integrase/0.517
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.516
3zsxN44Integrase/0.504
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.500
1poxFADPyruvate oxidase1.2.3.30.496
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.491
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.491
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.489
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.488
2wxvWXVCyclin-dependent kinase 22.7.11.220.485
4f650S9Fibroblast growth factor receptor 1/0.485
1ef92CPMethylmalonyl-CoA decarboxylase4.1.1.410.483
3ijdC2FMethylenetetrahydrofolate reductase/0.483
2bfyH1NAurora kinase B-A2.7.11.10.481
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.480
3h4vDVPPteridine reductase 11.5.1.330.479
3iok1P6Tyrosine-protein kinase JAK2/0.479
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.479
1pg3PRXAcetyl-coenzyme A synthetase/0.478
3dt1P40Mitogen-activated protein kinase 14/0.478
5e8ySTUTGF-beta receptor type-22.7.11.300.477
2c29NAPDihydroflavonol 4-reductase/0.476
2wihP48Cyclin-dependent kinase 22.7.11.220.475
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.474
4aotGW8Serine/threonine-protein kinase 102.7.11.10.474
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.473
3bhtMFRCyclin-dependent kinase 22.7.11.220.473
3drcMTXDihydrofolate reductase1.5.1.30.473
3pqbVGPPutative oxidoreductase/0.473
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.473
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2eleSAHDiphthine synthase/0.471
2p2qPRXAcetyl-coenzyme A synthetase/0.471
2pvnP63Casein kinase II subunit alpha2.7.11.10.471
4fod0UVALK tyrosine kinase receptor2.7.10.10.471
4jx1CAHCamphor 5-monooxygenase1.14.15.10.471
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.471
1eh4IC1Casein kinase I homolog 12.7.11.10.470
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.470
3fwjCAMCamphor 5-monooxygenase1.14.15.10.470
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.469
2pvjP44Casein kinase II subunit alpha2.7.11.10.469
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.469
4bgg844Activin receptor type-12.7.11.300.469
1ywnLIFVascular endothelial growth factor receptor 22.7.10.10.468
1zys199Serine/threonine-protein kinase Chk12.7.11.10.468
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.468
3mdmFJZCholesterol 24-hydroxylase/0.468
4a81DXCMajor pollen allergen Bet v 1-A/0.468
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.468
4l4cCAMCamphor 5-monooxygenase1.14.15.10.468
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.468
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.467
1zrzBI1Protein kinase C iota type2.7.11.130.467
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.467
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
3lqfNADGalactitol dehydrogenase/0.467
4a83DXCMajor pollen allergen Bet v 1-A/0.467
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
1rfuADPPyridoxal kinase2.7.1.350.466
3qlrNDPDihydrofolate reductase1.5.1.30.466
3up0D7SaceDAF-12/0.466
4enhFVXCholesterol 24-hydroxylase/0.466
1bygSTUTyrosine-protein kinase CSK/0.465
1t88CAMCamphor 5-monooxygenase1.14.15.10.465
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.465
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.464
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.464
2qblCAMCamphor 5-monooxygenase1.14.15.10.464
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.464
1hbvGANGag-Pol polyprotein/0.463
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.463
2ociTYCValacyclovir hydrolase3.10.463
4cd0AWJALK tyrosine kinase receptor2.7.10.10.463
4ure1PSCyclohexanol dehydrogenase/0.463
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.463
1gd1NADGlyceraldehyde-3-phosphate dehydrogenase/0.462
1t86CAMCamphor 5-monooxygenase1.14.15.10.462
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.462
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.462
2xa4AZ5Tyrosine-protein kinase JAK2/0.462
2z97CAMCamphor 5-monooxygenase1.14.15.10.462
3c16FOKAdenylate cyclase type 2/0.462
3c16FOKAdenylate cyclase type 5/0.462
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.461
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.461
1t85CAMCamphor 5-monooxygenase1.14.15.10.461
2np8CC3Aurora kinase A2.7.11.10.461
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.461
2wipP49Cyclin-dependent kinase 22.7.11.220.461
2zbaZBATrichothecene 3-O-acetyltransferase/0.461
3hmm855TGF-beta receptor type-12.7.11.300.461
3iaeD7KBenzaldehyde lyase/0.461
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.461
3vf80JETyrosine-protein kinase SYK2.7.10.20.461
4gmy0X5Tyrosine-protein kinase JAK2/0.461
4oztP1AEcdysone receptor, putative/0.461
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.461
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.460
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.460
2j4kU5PUridylate kinase2.7.4.220.460
3wrhCAMCamphor 5-monooxygenase1.14.15.10.460
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.460
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.460
4tuvCPZCytochrome P450 1191.140.460
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.459
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.459
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
2vttLZDCyclin-dependent kinase 22.7.11.220.459
2w2lNADD-mandelate dehydrogenase/0.459
3hl7I47Mitogen-activated protein kinase 14/0.459
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.459
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.459
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.459
4ek1CAMCamphor 5-monooxygenase1.14.15.10.459
4kip1R9Mitogen-activated protein kinase 14/0.459
1ia3TQ5Dihydrofolate reductase1.5.1.30.458
1jpaANPEphrin type-B receptor 22.7.10.10.458
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
3cgfJNFMitogen-activated protein kinase 102.7.11.240.458
3d84NDPDihydrofolate reductase1.5.1.30.458
3d8bADPFidgetin-like protein 13.6.40.458
3ggfGVDSerine/threonine-protein kinase 26/0.458
3qu0X40Cyclin-dependent kinase 22.7.11.220.458
3u9eCOALmo1369 protein/0.458
4aqc88ATyrosine-protein kinase JAK2/0.458
4i6gFADCryptochrome-2/0.458
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.458
1s3vTQDDihydrofolate reductase1.5.1.30.457
2btsU32Cyclin-dependent kinase 22.7.11.220.457
2opsHBQGag-Pol polyprotein2.7.7.490.457
2wpa889Cyclin-dependent kinase 22.7.11.220.457
3be9P04Casein kinase II subunit alpha2.7.11.10.457
3dxmN24Actin-related protein 3/0.457
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.457
3mqe416Prostaglandin G/H synthase 21.14.99.10.457
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.457
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.457
4bfzZVZPantothenate kinase2.7.1.330.457
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.457
1fvt106Cyclin-dependent kinase 22.7.11.220.456
1yrcCAMCamphor 5-monooxygenase1.14.15.10.456
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
2w6nOA2Biotin carboxylase6.3.4.140.456
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.456
3wrlCAMCamphor 5-monooxygenase1.14.15.10.456
4b7xNAPProbable oxidoreductase/0.456
4dc0NDPPutative ketoacyl reductase1.3.10.456
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.455
1e7qNAPGDP-L-fucose synthase/0.455
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1z1fSTLResveratrol synthase/0.455
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2bkzSBCCyclin-dependent kinase 22.7.11.220.455
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.455
4bb3KKAIsopenicillin N synthase1.21.3.10.455
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.455
4cukNAID-lactate dehydrogenase/0.455
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.455
4hge15VTyrosine-protein kinase JAK2/0.455
4nbwNADShort-chain dehydrogenase/reductase SDR/0.455
1mrxK57Gag-Pol polyprotein3.4.23.160.454
1nq14HYThyroid hormone receptor beta/0.454
1o76CAMCamphor 5-monooxygenase1.14.15.10.454
1v9aSAHUncharacterized protein/0.454
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
2j5xGSPADP-ribosylation factor 6/0.454
3hx4ANPCalmodulin-domain protein kinase 1/0.454
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.454
3l63CAMCamphor 5-monooxygenase1.14.15.10.454
3sa8K83Protease/0.454
3ttiKBIMitogen-activated protein kinase 102.7.11.240.454
3vjoANPEpidermal growth factor receptor2.7.10.10.454
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.454
4dymIYZActivin receptor type-12.7.11.300.454
4m9aFDAAcyl-CoA dehydrogenase/0.454
4oznATPAmmonium transporter/0.454
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.454
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.454
1mczRMNBenzoylformate decarboxylase4.1.1.70.453
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.453
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2e8rSAHDiphthine synthase/0.453
2feuCAMCamphor 5-monooxygenase1.14.15.10.453
2xs0ANPMitogen-activated protein kinase 82.7.11.240.453
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3cpsNADGlyceraldehyde-3-phosphate dehydrogenase/0.453
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3oibFDAPutative acyl-CoA dehydrogenase/0.453
3oom507Activin receptor type-12.7.11.300.453
3ufnROCGag-Pol polyprotein/0.453
3vtbTKAVitamin D3 receptor/0.453
4xg1LLPDiaminopimelate decarboxylase/0.453
4y8wSTRSteroid 21-hydroxylase/0.453
1powFADPyruvate oxidase1.2.3.30.452
1rx1NAPDihydrofolate reductase1.5.1.30.452
2o7pNAPRiboflavin biosynthesis protein RibD/0.452
2p33J07Mitogen-activated protein kinase 102.7.11.240.452
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.452
3fwgCAMCamphor 5-monooxygenase1.14.15.10.452
3hekBD0Heat shock protein HSP 90-alpha/0.452
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.452
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3sacAF8Protease/0.452
3t3r9PLCytochrome P450 2A61.14.130.452
4c62XWWTyrosine-protein kinase JAK2/0.452
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.452
4i22IREEpidermal growth factor receptor2.7.10.10.452
4pkl1GHUncharacterized protein/0.452
5e8wSTUTGF-beta receptor type-12.7.11.300.452
1bwsNDPGDP-L-fucose synthase/0.451
1di8DTQCyclin-dependent kinase 22.7.11.220.451
1e3eNAIAlcohol dehydrogenase 41.1.1.10.451
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
2i40BLZCyclin-dependent kinase 22.7.11.220.451
2j9mPY8Cyclin-dependent kinase 22.7.11.220.451
2qoqANPEphrin type-A receptor 32.7.10.10.451
2rkvZBATrichothecene 3-O-acetyltransferase/0.451
2xikJ60Serine/threonine-protein kinase 252.7.11.10.451
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.451
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.451
3maaFKPAdenylate cyclase type 2/0.451
3maaFKPAdenylate cyclase type 5/0.451
3mg3ECHOrange carotenoid-binding protein/0.451
3zuyTCHTransporter/0.451
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.451
4cgfUJ6Integrase/0.451
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.451
4l4dCAMCamphor 5-monooxygenase1.14.15.10.451
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.451
5cb3APRO-acetyl-ADP-ribose deacetylase/0.451
5eccNAPDehydrofolate reductase type I/0.451
1dcyI3NPhospholipase A2, membrane associated/0.450
1dz8CAMCamphor 5-monooxygenase1.14.15.10.450
1f8fNADBenzyl alcohol dehydrogenase/0.450
2hk51BMTyrosine-protein kinase HCK2.7.10.20.450
2qbmCAMCamphor 5-monooxygenase1.14.15.10.450
3a60STURibosomal protein S6 kinase beta-12.7.11.10.450
3b9lAZZSerum albumin/0.450
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.450
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.450
3eljGS7Mitogen-activated protein kinase 82.7.11.240.450
3em4DR7Gag-Pol polyprotein3.4.23.160.450
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.450
3lfqA28Cyclin-dependent kinase 22.7.11.220.450
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.450
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.450
3zdu38RCyclin-dependent kinase-like 32.7.11.220.450
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4erwSTUCyclin-dependent kinase 22.7.11.220.450
4fkw62KCyclin-dependent kinase 22.7.11.220.450
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.450
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.450
1ahiCHO7-alpha-hydroxysteroid dehydrogenase1.1.1.1590.449
1fxsNAPGDP-L-fucose synthase/0.449
1uyuCAMCamphor 5-monooxygenase1.14.15.10.449
1x2hLPALipoate-protein ligase A6.3.1.200.449
2balPQAMitogen-activated protein kinase 14/0.449
2hk9NAPShikimate dehydrogenase (NADP(+))/0.449
2i0aMUIProtease/0.449
2qlnF59Glycogen phosphorylase, muscle form2.4.1.10.449
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3lfsA07Cyclin-dependent kinase 22.7.11.220.449
3s2pPMUCyclin-dependent kinase 22.7.11.220.449
4b1fKRHGlutamate racemase/0.449
4nieNBHNuclear receptor ROR-gamma/0.449
1oiyN41Cyclin-dependent kinase 22.7.11.220.448
1pkdUCNCyclin-dependent kinase 22.7.11.220.448
1sozVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.448
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.448
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.448
2cchATPCyclin-dependent kinase 22.7.11.220.448
2qnpQN2Gag-Pol polyprotein3.4.23.160.448
2r0pK2CPutative FAD-monooxygenase/0.448
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.448
2wo7ASVIsopenicillin N synthase1.21.3.10.448
2zaxCAMCamphor 5-monooxygenase1.14.15.10.448
3a25SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase/0.448
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.448
3raiX85Cyclin-dependent kinase 22.7.11.220.448
3vquO22Dual specificity protein kinase TTK2.7.12.10.448
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.448
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.448
4gk2L66Ephrin type-A receptor 32.7.10.10.448
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4jbqVX6Aurora kinase A2.7.11.10.448
4l4xNDPAmphI/0.448
4m6p20RNicotinamide phosphoribosyltransferase2.4.2.120.448
4nmbFADBifunctional protein PutA/0.448
4qmpDKISerine/threonine-protein kinase 242.7.11.10.448
4qo9627Serine/threonine-protein kinase 242.7.11.10.448
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
1eioGCHGastrotropin/0.447
1h51FMNPentaerythritol tetranitrate reductase/0.447
1phhFADp-hydroxybenzoate hydroxylase/0.447
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.447
1yrdCAMCamphor 5-monooxygenase1.14.15.10.447
2m56CAMCamphor 5-monooxygenase1.14.15.10.447
2w9hTOPDihydrofolate reductase1.5.1.30.447
2zjwREFCasein kinase II subunit alpha2.7.11.10.447
2znq401Peroxisome proliferator-activated receptor delta/0.447
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.447
3deiRXBCaspase-33.4.22.560.447
3ttjJBIMitogen-activated protein kinase 102.7.11.240.447
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.447
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.447
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.447
5ifiPRXAcetyl-coenzyme A synthetase/0.447
1cqp803Integrin alpha-L/0.446
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.446
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.446
2ghlLIBMitogen-activated protein kinase 14/0.446
2gvdFKPAdenylate cyclase type 2/0.446
2gvdFKPAdenylate cyclase type 5/0.446
2hog710Serine/threonine-protein kinase Chk12.7.11.10.446
2p2bPRXAcetyl-coenzyme A synthetase/0.446
3iphG11Mitogen-activated protein kinase 14/0.446
3p3zP3ZPutative cytochrome P450/0.446
3r7kFDAProbable acyl CoA dehydrogenase/0.446
3rm618ZCyclin-dependent kinase 22.7.11.220.446
3so9017Pol protein/0.446
4a8v2ANMajor pollen allergen Bet v 1-J/0.446
4btjADPTau-tubulin kinase 12.7.11.10.446
4fv6E57Mitogen-activated protein kinase 12.7.11.240.446
4g2fC07Ephrin type-A receptor 32.7.10.10.446
4mv8ACPBiotin carboxylase6.3.4.140.446
4rrxLURProstaglandin G/H synthase 21.14.99.10.446
5cp4CAMCamphor 5-monooxygenase1.14.15.10.446
1guyNADMalate dehydrogenase/0.445
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1iwiCAMCamphor 5-monooxygenase1.14.15.10.445
1m78NDPDihydrofolate reductase1.5.1.30.445
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.445
1vceSAHDiphthine synthase/0.445
1zemNADXylitol dehydrogenase/0.445
2b35TCLEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2bfmTOPPteridine reductase 11.5.1.330.445
2excJNKMitogen-activated protein kinase 102.7.11.240.445
2pvhP19Casein kinase II subunit alpha2.7.11.10.445
2qo9ANPEphrin type-A receptor 32.7.10.10.445
2r1rTTPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.445
2v5aLZLBiotin carboxylase6.3.4.140.445
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.445
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.445
3ai3NDPNADPH-sorbose reductase/0.445
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.445
3flyFLYMitogen-activated protein kinase 14/0.445
3igoANPCalmodulin-domain protein kinase 1, putative/0.445
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.445
3mpt1GKMitogen-activated protein kinase 14/0.445
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.445
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.445
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.445
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.445
3zep1NXTyrosine-protein kinase JAK32.7.10.20.445
4ead0NPThymidine phosphorylase2.4.2.40.445
4ly91YYGlucokinase regulatory protein/0.445
4ocvANPAminoglycoside phosphotransferase/0.445
4rquNADAlcohol dehydrogenase class-P/0.445
5ax35IDMitogen-activated protein kinase 12.7.11.240.445
5hynSAHHistone-lysine N-methyltransferase EZH22.1.1.430.445
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1ia1NDPDihydrofolate reductase1.5.1.30.444
1jq5NADGlycerol dehydrogenase1.1.1.60.444
1lriCLRBeta-elicitin cryptogein/0.444
1nooCAHCamphor 5-monooxygenase1.14.15.10.444
1q3ePCGPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.444
1r6g442Thyroid hormone receptor beta/0.444
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.444
1svlADPLarge T antigen3.6.40.444
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
2iviACWIsopenicillin N synthase1.21.3.10.444
2iw94SPCyclin-dependent kinase 22.7.11.220.444
2p2jPRXAcetyl-coenzyme A synthetase/0.444
2pauD5M5'-deoxynucleotidase YfbR/0.444
2v59LZKBiotin carboxylase6.3.4.140.444
2xvu9DNSerum albumin/0.444
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.444
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.444
3hllI45Mitogen-activated protein kinase 14/0.444
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.444
3nbvANPKetohexokinase/0.444
3ormAGSSerine/threonine protein kinase/0.444
3q44D50M1 family aminopeptidase3.4.110.444
3qrsNK8Gag-Pol polyprotein3.4.23.160.444
3qwkX62Cyclin-dependent kinase 22.7.11.220.444
3r4b74TGag-Pol polyprotein/0.444
3sheI85MAP kinase-activated protein kinase 32.7.11.10.444
3tucFPWTyrosine-protein kinase SYK2.7.10.20.444
3v1yNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.444
4a87NARMajor pollen allergen Bet v 1-A/0.444
4bqrIBHEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4plpNADHomospermidine synthase2.5.1.440.444
4trj665Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4y93746Tyrosine-protein kinase/0.444
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.444
5ez7FADProbable FAD-dependent oxidoreductase PA4991/0.444
1dz6CAMCamphor 5-monooxygenase1.14.15.10.443
1fmjRTLRetinol dehydratase/0.443
1iwjCAMCamphor 5-monooxygenase1.14.15.10.443
1ke9LS5Cyclin-dependent kinase 22.7.11.220.443
1ma0NADAlcohol dehydrogenase class-31.1.1.10.443
1mp0NADAlcohol dehydrogenase class-31.1.1.10.443
1msnJE2Gag-Pol polyprotein3.4.23.160.443
1xlsREARetinoic acid receptor RXR-alpha/0.443
1ykdCMPAdenylate cyclase/0.443
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2chlDKICasein kinase I isoform gamma-32.7.11.10.443
2j4z626Aurora kinase A2.7.11.10.443
2uzeC95Cyclin-dependent kinase 22.7.11.220.443
2xvw9NRSerum albumin/0.443
2y3sTIRTamL/0.443
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.443
3q7dNPXProstaglandin G/H synthase 21.14.99.10.443
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.443
4erkOLOMitogen-activated protein kinase 12.7.11.240.443
4jx1CAMCamphor 5-monooxygenase1.14.15.10.443
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.443
4qnaX11Serine/threonine-protein kinase 242.7.11.10.443
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.443
1agwSU2Fibroblast growth factor receptor 1/0.442
1aiqCB3Thymidylate synthase/0.442
1u54ACPActivated CDC42 kinase 1/0.442
1yb5NAPQuinone oxidoreductase1.6.5.50.442
2abi1CAMineralocorticoid receptor/0.442
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.442
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.442
2g8yNADHydroxycarboxylate dehydrogenase B/0.442
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.442
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.442
2p7zOHTEstrogen-related receptor gamma/0.442
2q70DC8Estrogen receptor/0.442
2xhxT5MHeat shock protein HSP 90-alpha/0.442
3akm11DFatty acid-binding protein, intestinal/0.442
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.442
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.442
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.442
3zrbOR8Progesterone receptor/0.442
4a84DXCMajor pollen allergen Bet v 1-A/0.442
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.442
4bcpT3CCyclin-dependent kinase 22.7.11.220.442
4ek816KCyclin-dependent kinase 22.7.11.220.442
4eqwCOACoenzyme A disulfide reductase/0.442
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.442
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.442
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
4jln18VDeoxycytidine kinase2.7.1.740.442
4k9dNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1bk0ACVIsopenicillin N synthase1.21.3.10.441
1bv7XV6Gag-Pol polyprotein3.4.23.160.441
1c1dNAIPhenylalanine dehydrogenase/0.441
1cjkFOKAdenylate cyclase type 2/0.441
1cjkFOKAdenylate cyclase type 5/0.441
1gqtACPRibokinase/0.441
1hb1OCVIsopenicillin N synthase1.21.3.10.441
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.441
1oirHDYCyclin-dependent kinase 22.7.11.220.441
1osvCHCBile acid receptor/0.441
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.441
1qoqIGPTryptophan synthase alpha chain/0.441
1rw8580TGF-beta receptor type-12.7.11.300.441
1rx8FOLDihydrofolate reductase1.5.1.30.441
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1ungALHCyclin-dependent-like kinase 52.7.11.10.441
2a1nCAMCamphor 5-monooxygenase1.14.15.10.441
2acxANPG protein-coupled receptor kinase 62.7.11.160.441
2bhhRYUCyclin-dependent kinase 22.7.11.220.441
2c5nCK8Cyclin-dependent kinase 22.7.11.220.441
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.441
2i4xKGQProtease/0.441
2pcgSAHDiphthine synthase/0.441
2xrwANPMitogen-activated protein kinase 82.7.11.240.441
2yi7BZ8Heat shock protein HSP 90-alpha/0.441
3akn11DFatty acid-binding protein, intestinal/0.441
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.441
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
3f63GTXGlutathione transferase GST1-4/0.441
3nga3NGCasein kinase II subunit alpha2.7.11.10.441
3nmpPYVAbscisic acid receptor PYL2/0.441
3nxe2NCProtease/0.441
3q5dGDPAtlastin-13.6.50.441
3ql8X01Cyclin-dependent kinase 22.7.11.220.441
3qn8NI7Gag-Pol polyprotein3.4.23.160.441
3t2yFADSulfide-quinone reductase/0.441
3zh8C58Protein kinase C iota type2.7.11.130.441
4ajn88VL-lactate dehydrogenase A chain1.1.1.270.441
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4gk3L87Ephrin type-A receptor 32.7.10.10.441
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4idgNADPutative UDP-glucose 4-epimerase/0.441
4ix6ADPUncharacterized protein/0.441
4jnm1LJNicotinamide phosphoribosyltransferase2.4.2.120.441
4kin1M8Mitogen-activated protein kinase 14/0.441
4l4bCAMCamphor 5-monooxygenase1.14.15.10.441
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.441
4oeyDHTAndrogen receptor/0.441
4otyLURProstaglandin G/H synthase 21.14.99.10.441
5d3qGDPDynamin-13.6.5.50.441
5d4vSAHUncharacterized protein MJ0489/0.441
5dr2ATPAurora kinase A2.7.11.10.441
1a7kNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.440
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.440
1nqoNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
1r2jFADFkbI/0.440
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.440
1ya3STRMineralocorticoid receptor/0.440
2bglNAJSecoisolariciresinol dehydrogenase1.1.1.3310.440
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2fnaADPUncharacterized protein/0.440
2j5sKTAAlr4455 protein/0.440
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.440
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.440
2z54AB1Gag-Pol polyprotein3.4.23.160.440
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3d574HYThyroid hormone receptor beta/0.440
3d76NBBPheromone-binding protein ASP1/0.440
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.440
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.440
3l0lHC3Nuclear receptor ROR-gamma/0.440
3lltANPProtein serine/threonine kinase-1/0.440
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.440
3nu3478Gag-Pol polyprotein3.4.23.160.440
3p7nFMNLight-activated DNA-binding protein EL222/0.440
3r83Z14Cyclin-dependent kinase 22.7.11.220.440
3wrmCAMCamphor 5-monooxygenase1.14.15.10.440
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4apuOR8Progesterone receptor/0.440
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.440
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
4dfrMTXDihydrofolate reductase1.5.1.30.440
4fyn0VETyrosine-protein kinase SYK2.7.10.20.440
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4jvlESTEstrogen sulfotransferase2.8.2.40.440
4k6fNAPPutative Acetoacetyl-CoA reductase/0.440
4kbk1QGCasein kinase I isoform delta2.7.11.10.440
4olfHFGProline--tRNA ligase6.1.1.150.440
4u2lSFDCholesterol oxidase1.1.3.60.440