sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 1.000 | |
| 2wcg | MT5 | Glucosylceramidase | 3.2.1.45 | 0.565 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.559 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.520 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.516 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.506 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.505 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.504 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.501 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.499 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.498 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.498 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.497 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.496 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.494 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.493 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.489 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.487 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.487 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.487 | |
| 4kl1 | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.487 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.486 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.485 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.485 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.485 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.484 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.483 | |
| 4lut | DCS | Alanine racemase | / | 0.483 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.483 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.482 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.481 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.481 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.480 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.480 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.480 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.480 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.479 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.478 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.477 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.477 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.476 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.476 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.476 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.476 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.475 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.474 | |
| 1c9h | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1B | 5.2.1.8 | 0.474 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.474 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.474 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.474 | |
| 4ca8 | 3ES | Angiotensin-converting enzyme | 3.4.15.1 | 0.474 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.474 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.474 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.473 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.473 | |
| 2gg3 | U13 | Methionine aminopeptidase | / | 0.473 | |
| 1i75 | NOJ | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.472 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.472 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.472 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.472 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.471 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.471 | |
| 2x94 | X94 | Angiotensin-converting enzyme | 3.4.15.1 | 0.471 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.471 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.470 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.470 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.470 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.470 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.470 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.470 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.470 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.469 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.469 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.469 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.469 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.468 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.468 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.468 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.467 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.467 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.467 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.467 | |
| 4lxl | PD2 | Lysine-specific demethylase 4B | 1.14.11 | 0.467 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.466 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.466 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.466 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.466 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.465 | |
| 2xtk | AZM | Class III chitinase ChiA1 | / | 0.465 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.465 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.465 | |
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.464 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.464 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.464 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.464 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.464 | |
| 4fli | Y16 | Methionine aminopeptidase 1 | / | 0.464 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.463 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.463 | |
| 1n5i | TMP | Thymidylate kinase | 2.7.4.9 | 0.463 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.463 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.463 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.463 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 3i0o | SMI | Spectinomycin phosphotransferase | / | 0.463 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.463 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.463 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.463 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.463 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.462 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.462 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.462 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.462 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.462 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.461 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.461 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.461 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.461 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.461 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.460 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.460 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.460 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.460 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.460 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.460 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.459 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.459 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.458 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.458 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.458 | |
| 4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.458 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.458 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.458 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 4azw | SAM | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.457 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.457 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.457 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.457 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.457 | |
| 1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.456 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.456 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.456 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.455 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.455 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.455 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.455 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.455 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.455 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.455 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.455 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.455 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.455 | |
| 5i2f | BS5 | Histidine triad nucleotide-binding protein 1 | 3 | 0.455 | |
| 1vft | DCS | Alanine racemase | / | 0.454 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.454 | |
| 1xnz | FCD | Methionine aminopeptidase | / | 0.454 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.454 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.454 | |
| 2x95 | X95 | Angiotensin-converting enzyme | 3.4.15.1 | 0.454 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.454 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.454 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.454 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.454 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.454 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.454 | |
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.453 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.453 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.453 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.453 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.453 | |
| 1n75 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.452 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.452 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.451 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.451 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.451 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2rgu | 356 | Dipeptidyl peptidase 4 | / | 0.451 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.451 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.451 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.451 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.451 | |
| 4j7h | TRH | PCZA361.3 | / | 0.451 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.451 | |
| 4xwt | U5P | Ribonuclease J | / | 0.451 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.451 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.450 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.450 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.450 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.450 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.450 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.450 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.450 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.450 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.450 | |
| 4zwe | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.450 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.449 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2wca | NP6 | O-GlcNAcase BT_4395 | / | 0.449 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.449 | |
| 3irh | DTP | HD domain protein | / | 0.449 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.449 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.449 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4jkv | 1KS | Smoothened homolog | / | 0.449 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.449 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.449 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.449 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.448 | |
| 4hn1 | TYD | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.448 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.448 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.448 | |
| 4rxs | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.448 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.447 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.447 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.447 | |
| 3e6e | DCS | Alanine racemase | / | 0.447 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.447 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.447 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.447 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.446 | |
| 1j36 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.446 | |
| 2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.446 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.446 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.446 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.446 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.446 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.446 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.446 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.446 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.446 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.445 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.445 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3jsz | UPG | Uncharacterized protein | / | 0.445 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.445 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.444 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.444 | |
| 2q93 | B21 | Methionine aminopeptidase | / | 0.444 | |
| 3arp | DEQ | Chitinase A | / | 0.444 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.444 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.444 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.444 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.444 | |
| 4uoc | NCN | CinA-like protein | / | 0.444 | |
| 4wrk | DUP | DUTPase | / | 0.444 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.443 | |
| 1jil | 485 | Tyrosine--tRNA ligase | / | 0.443 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2e91 | ZOL | Geranylgeranyl pyrophosphate synthase | / | 0.443 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.443 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.443 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.443 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3ei8 | PL5 | LL-diaminopimelate aminotransferase, chloroplastic | / | 0.443 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.443 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.443 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.443 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 4zwm | PLP | Ornithine aminotransferase, mitochondrial, putative | / | 0.443 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.442 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.442 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.442 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.442 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.442 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.442 | |
| 4drp | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.442 | |
| 4f6r | GDP | Tubulin beta chain | / | 0.442 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.442 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.442 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2wzg | UPG | Uncharacterized protein | / | 0.441 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.441 | |
| 2zh6 | ATP | CCA-adding enzyme | 2.7.7.72 | 0.441 | |
| 3lzx | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.441 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3x2e | NAI | Adenosylhomocysteinase | / | 0.441 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.440 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.440 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.440 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.440 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.440 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.440 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.440 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.440 | |
| 2pja | 33Z | Carboxypeptidase B | / | 0.440 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.440 | |
| 3f28 | S7B | Thermolysin | 3.4.24.27 | 0.440 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.440 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ovs | CTP | CCA-adding enzyme | 2.7.7.72 | 0.440 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3zxi | TYA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.440 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.440 | |
| 4e31 | JHZ | Methyltransferase | / | 0.440 | |
| 4e32 | DWN | Methyltransferase | / | 0.440 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.440 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.440 |