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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2acxANPG protein-coupled receptor kinase 62.7.11.16

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2acxANPG protein-coupled receptor kinase 62.7.11.161.000
3c4wATPRhodopsin kinase/0.584
2qo9ANPEphrin type-A receptor 32.7.10.10.583
3c50ADPRhodopsin kinase/0.567
3qc9ADPRhodopsin kinase/0.565
2hog710Serine/threonine-protein kinase Chk12.7.11.10.560
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.558
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.551
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.551
3c4xATPRhodopsin kinase/0.550
3t8oATPRhodopsin kinase/0.546
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.545
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.542
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.541
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.540
3c4zADPRhodopsin kinase/0.540
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.536
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.535
4qo9627Serine/threonine-protein kinase 242.7.11.10.534
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.529
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.529
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.525
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.522
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.521
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.521
2qoqANPEphrin type-A receptor 32.7.10.10.521
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.520
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.518
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.518
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.517
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.517
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.517
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.516
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.516
4wboANWRhodopsin kinase/0.516
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.515
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.515
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.515
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.514
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.513
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.513
3a7jADPSerine/threonine-protein kinase 242.7.11.10.513
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.513
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.512
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.512
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.511
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.510
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.510
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.510
2henADPEphrin type-B receptor 22.7.10.10.509
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.509
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.509
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.509
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.508
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.508
4qnaX11Serine/threonine-protein kinase 242.7.11.10.508
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.505
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.505
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.504
4jrnANPRhoptry kinase family protein/0.504
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.503
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.503
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.503
4g2fC07Ephrin type-A receptor 32.7.10.10.503
1zrzBI1Protein kinase C iota type2.7.11.130.501
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.500
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.500
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.499
4b99R4LMitogen-activated protein kinase 72.7.11.240.498
4qms1N1Serine/threonine-protein kinase 242.7.11.10.498
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.497
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.497
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.496
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.496
1u54ACPActivated CDC42 kinase 1/0.495
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.495
2py3ACPFibroblast growth factor receptor 2/0.495
3a7hATPSerine/threonine-protein kinase 242.7.11.10.495
3lctADPALK tyrosine kinase receptor2.7.10.10.495
4qmzB49Serine/threonine-protein kinase 242.7.11.10.495
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.494
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.494
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.493
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.492
4gu94GUFocal adhesion kinase 12.7.10.20.492
4xj3GTPCyclic GMP-AMP synthase/0.492
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.491
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.491
2qo7ANPEphrin type-A receptor 32.7.10.10.491
2qocANPEphrin type-A receptor 32.7.10.10.491
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.491
2xvdAS6Ephrin type-B receptor 42.7.10.10.491
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.490
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.490
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.490
4gk3L87Ephrin type-A receptor 32.7.10.10.490
4xlvACPInsulin receptor2.7.10.10.490
5dt3ATPAurora kinase A2.7.11.10.490
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.488
4k33ACPFibroblast growth factor receptor 32.7.10.10.488
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.488
5dn3ATPAurora kinase A2.7.11.10.488
1csnATPCasein kinase I homolog 12.7.11.10.487
1ir3ANPInsulin receptor2.7.10.10.487
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.487
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.487
2ckeIQUDeath-associated protein kinase 2/0.487
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.487
4fob0USALK tyrosine kinase receptor2.7.10.10.487
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.487
4l9i8PRRhodopsin kinase/0.487
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.486
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.486
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.486
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.486
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.486
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.486
3my5RFZCyclin-dependent kinase 22.7.11.220.485
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.485
4qmlANPSerine/threonine-protein kinase 242.7.11.10.485
2etm7PYFocal adhesion kinase 12.7.10.20.484
3q5iANPProtein kinase, putative/0.484
3zh8C58Protein kinase C iota type2.7.11.130.484
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.484
4eomATPCyclin-dependent kinase 22.7.11.220.484
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.484
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.483
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.483
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.483
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.483
4fuxE75Mitogen-activated protein kinase 12.7.11.240.483
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.483
4qnyANPMitogen activated protein kinase, putative/0.483
1gy3ATPCyclin-dependent kinase 22.7.11.220.482
1ol5ADPAurora kinase A2.7.11.10.482
2j0lANPFocal adhesion kinase 12.7.10.20.482
3bu5ATPInsulin receptor2.7.10.10.482
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.482
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.482
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.482
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.482
1ol7ADPAurora kinase A2.7.11.10.481
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.481
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.481
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.481
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.481
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.481
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.481
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.481
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.480
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.480
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.480
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.480
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.480
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.480
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.480
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.480
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.480
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.479
1ol6ATPAurora kinase A2.7.11.10.478
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.478
5dt4ATPAurora kinase A2.7.11.10.478
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.477
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.477
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.477
2ittAEEEpidermal growth factor receptor2.7.10.10.477
2izt23DCasein kinase I isoform gamma-32.7.11.10.477
2w4kADPDeath-associated protein kinase 12.7.11.10.477
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.477
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.477
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.477
4g3pUD1Bifunctional protein GlmU/0.477
2itnANPEpidermal growth factor receptor2.7.10.10.476
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.476
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.476
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.476
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.476
4utdACPAurora kinase A2.7.11.10.476
1bygSTUTyrosine-protein kinase CSK/0.475
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.475
2pzpACPFibroblast growth factor receptor 2/0.475
2vd5BI8Myotonin-protein kinase2.7.11.10.475
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.475
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.475
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.475
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.475
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.475
4jia1K3Tyrosine-protein kinase JAK2/0.475
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.475
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.474
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.474
2j0k4STFocal adhesion kinase 12.7.10.20.474
2x1nX1NCyclin-dependent kinase 22.7.11.220.474
3a62STURibosomal protein S6 kinase beta-12.7.11.10.474
3gu5ANPDeath-associated protein kinase 12.7.11.10.474
3igoANPCalmodulin-domain protein kinase 1, putative/0.474
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.473
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.473
3vjoANPEpidermal growth factor receptor2.7.10.10.473
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.473
4lopSB4Mitogen-activated protein kinase 14/0.473
1jpaANPEphrin type-B receptor 22.7.10.10.472
3zxtACPDeath-associated protein kinase 12.7.11.10.472
4bb432WEphrin type-B receptor 42.7.10.10.472
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.472
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.471
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.471
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.471
4eooATPCyclin-dependent kinase 22.7.11.220.471
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.471
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.471
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.471
5aacVGHALK tyrosine kinase receptor2.7.10.10.471
2x9fX9FEphrin type-B receptor 42.7.10.10.470
4k8aK8AFocal adhesion kinase 12.7.10.20.470
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.470
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.470
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.469
2z7lS91Mitogen-activated protein kinase 12.7.11.240.469
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.469
5auwQUEDeath-associated protein kinase 12.7.11.10.469
5cvhADPCasein kinase II subunit alpha2.7.11.10.469
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.468
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.468
2izuP01Casein kinase I isoform gamma-32.7.11.10.468
3bqr4RBDeath-associated protein kinase 3/0.468
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.468
4gk2L66Ephrin type-A receptor 32.7.10.10.468
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.467
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.467
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.467
3ormAGSSerine/threonine protein kinase/0.466
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.466
3sheI85MAP kinase-activated protein kinase 32.7.11.10.466
4aguD15Cyclin-dependent kinase-like 1/0.466
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.466
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.466
1oiyN41Cyclin-dependent kinase 22.7.11.220.465
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.465
2bkzSBCCyclin-dependent kinase 22.7.11.220.465
2wxvWXVCyclin-dependent kinase 22.7.11.220.465
3gu6ADPDeath-associated protein kinase 12.7.11.10.465
4erkOLOMitogen-activated protein kinase 12.7.11.240.465
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.465
4fyn0VETyrosine-protein kinase SYK2.7.10.20.465
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.465
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.465
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.464
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.464
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.464
2ituITQEpidermal growth factor receptor2.7.10.10.464
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.464
2uzdC85Cyclin-dependent kinase 22.7.11.220.464
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.464
3i60E86Mitogen-activated protein kinase 12.7.11.240.464
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.464
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.464
4j97ACPFibroblast growth factor receptor 2/0.464
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.464
2pz5ACPFibroblast growth factor receptor 2/0.463
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.463
4bbe3O4Tyrosine-protein kinase JAK2/0.463
4bbfO19Tyrosine-protein kinase JAK2/0.463
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.463
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.463
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.462
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.462
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.462
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.462
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.462
2z4sADPChromosomal replication initiator protein DnaA/0.462
3frqERYErythromycin resistance repressor protein/0.462
3hx4ANPCalmodulin-domain protein kinase 1/0.462
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.462
4bcqTJFCyclin-dependent kinase 22.7.11.220.462
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.462
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.462
4n57ADPAPH(2'')-Id/0.462
4oavACP2-5A-dependent ribonuclease3.1.260.462
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.461
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.461
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.461
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.461
4b8zNAPGDP-L-fucose synthase1.1.1.2710.461
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.461
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.461
5dnrATPAurora kinase A2.7.11.10.461
5drdATPAurora kinase A2.7.11.10.461
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.460
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.460
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.460
3erkSB4Mitogen-activated protein kinase 12.7.11.240.460
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.460
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.460
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.460
4fod0UVALK tyrosine kinase receptor2.7.10.10.460
4gt3ATPMitogen-activated protein kinase 12.7.11.240.460
4j95ACPFibroblast growth factor receptor 2/0.460
4nm5ADPGlycogen synthase kinase-3 beta2.7.11.260.460
1cm8ANPMitogen-activated protein kinase 12/0.459
1jnkANPMitogen-activated protein kinase 102.7.11.240.459
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.459
2ft9CHDFatty acid-binding protein 2, liver/0.459
2ghlLIBMitogen-activated protein kinase 14/0.459
2itvANPEpidermal growth factor receptor2.7.10.10.459
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.459
2uzlC94Cyclin-dependent kinase 22.7.11.220.459
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.459
2y6o1N1Ephrin type-A receptor 42.7.10.10.459
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.459
3a8wATPProtein kinase C iota type2.7.11.130.459
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.459
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.459
3iw4LW4Protein kinase C alpha type2.7.11.130.459
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.459
3u9eCOALmo1369 protein/0.459
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.459
5dosATPAurora kinase A2.7.11.10.459
5l8lADPAurora kinase A2.7.11.10.459
1g4tFTPThiamine-phosphate synthase/0.458
2balPQAMitogen-activated protein kinase 14/0.458
3dt1P40Mitogen-activated protein kinase 14/0.458
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.458
4ix4ADPUncharacterized protein/0.458
4ix5ANPUncharacterized protein/0.458
4jboWPHAurora kinase A2.7.11.10.458
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.458
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.458
4yuqKS1Calmodulin-like domain protein kinase/0.458
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.457
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.457
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.457
2yaaATPDeath-associated protein kinase 2/0.457
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.457
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.457
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.457
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.457
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.457
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.457
4riyADPEpidermal growth factor receptor2.7.10.10.457
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.456
2wqeADPAurora kinase A2.7.11.10.456
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.456
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.456
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.456
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.456
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.455
2xikJ60Serine/threonine-protein kinase 252.7.11.10.455
2xneASHAurora kinase A2.7.11.10.455
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.455
4pl3ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.455
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.455
1h1s4SPCyclin-dependent kinase 22.7.11.220.454
1lp4ANPCasein kinase II subunit alpha2.7.11.10.454
1unlRRCCyclin-dependent-like kinase 52.7.11.10.454
2ghmLICMitogen-activated protein kinase 14/0.454
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.454
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.454
2xuuADPDeath-associated protein kinase 12.7.11.10.454
3fklFKLMitogen-activated protein kinase 14/0.454
3gubGUBDeath-associated protein kinase 12.7.11.10.454
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.454
4cd0AWJALK tyrosine kinase receptor2.7.10.10.454
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.454
4gmy0X5Tyrosine-protein kinase JAK2/0.454
4u03GTPCyclic GMP-AMP synthase/0.454
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.454
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.453
2cjmATPCyclin-dependent kinase 22.7.11.220.453
2eb3ANPEpidermal growth factor receptor2.7.10.10.453
2itpAEEEpidermal growth factor receptor2.7.10.10.453
2j7t274Serine/threonine-protein kinase 102.7.11.10.453
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.453
2xp2VGHALK tyrosine kinase receptor2.7.10.10.453
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.453
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.453
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.453
4foc0UUALK tyrosine kinase receptor2.7.10.10.453
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.453
4i22IREEpidermal growth factor receptor2.7.10.10.453
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.453
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.453
4nks2M2Fibroblast growth factor receptor 1/0.453
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.453
1mp8ADPFocal adhesion kinase 12.7.10.20.452
1wlvCOAPhenylacetic acid degradation protein PaaI/0.452
2cchATPCyclin-dependent kinase 22.7.11.220.452
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.452
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.452
3f8kCOAUncharacterized protein/0.452
3mpaSB2Mitogen-activated protein kinase 14/0.452
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.452
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.452
1aq1STUCyclin-dependent kinase 22.7.11.220.451
1finATPCyclin-dependent kinase 22.7.11.220.451
1jstATPCyclin-dependent kinase 22.7.11.220.451
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.451
2i40BLZCyclin-dependent kinase 22.7.11.220.451
2itwITQEpidermal growth factor receptor2.7.10.10.451
2j0j4STFocal adhesion kinase 12.7.10.20.451
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.451
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.451
3k5uPFQAurora kinase A2.7.11.10.451
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.451
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.451
4id71G0Activated CDC42 kinase 1/0.451
4jqeANPCasein kinase II subunit alpha2.7.11.10.451
4jr7GNPCasein kinase II subunit alpha2.7.11.10.451
5l8jADPAurora kinase A2.7.11.10.451
1bwsNDPGDP-L-fucose synthase/0.450
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.450
2c6tDT5Cyclin-dependent kinase 22.7.11.220.450
2p33J07Mitogen-activated protein kinase 102.7.11.240.450
2yyuC5POrotidine 5'-phosphate decarboxylase/0.450
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3mdvCL6Cholesterol 24-hydroxylase/0.450
3nszANPCasein kinase II subunit alpha2.7.11.10.450
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.450
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.450
4fv6E57Mitogen-activated protein kinase 12.7.11.240.450
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.450
4jbqVX6Aurora kinase A2.7.11.10.450
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.450
5av4GENDeath-associated protein kinase 12.7.11.10.450
1pkdUCNCyclin-dependent kinase 22.7.11.220.449
1tqf32PBeta-secretase 13.4.23.460.449
2ijmATPFocal adhesion kinase 12.7.10.20.449
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.449
2yn8STUEphrin type-B receptor 42.7.10.10.449
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.449
3bheBZNGag-Pol polyprotein3.4.23.160.449
3wowANPCasein kinase II subunit alpha2.7.11.10.449
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.449
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.449
4bcnT9NCyclin-dependent kinase 22.7.11.220.449
4e4m0NHTyrosine-protein kinase JAK2/0.449
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.449
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.449
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.449
4g170VNCasein kinase I isoform gamma-32.7.11.10.449
4jq7KJQEpidermal growth factor receptor2.7.10.10.449
4loqSB4Mitogen-activated protein kinase 14/0.449
2y9qANPMitogen-activated protein kinase 12.7.11.240.448
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.448
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.448
3miaANPCyclin-dependent kinase 92.7.11.220.448
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.448
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.448
4deeADPAurora kinase A2.7.11.10.448
4e5yNDPGDP-L-fucose synthase1.1.1.2710.448
4gxs0YSGlutamate receptor 2/0.448
4jrvKJVEpidermal growth factor receptor2.7.10.10.448
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.448
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.447
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.447
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.447
1fvv107Cyclin-dependent kinase 22.7.11.220.446
1m17AQ4Epidermal growth factor receptor2.7.10.10.446
2c4g514Cyclin-dependent kinase 22.7.11.220.446
2dwbANPAurora kinase A2.7.11.10.446
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.446
2vrx447Aurora kinase B-A2.7.11.10.446
2vwy7X5Ephrin type-B receptor 42.7.10.10.446
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.446
3ddpRC8Cyclin-dependent kinase 22.7.11.220.446
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/0.446
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.446
4eh60ONMitogen-activated protein kinase 14/0.446
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.446
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.446
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.446
4qmySTUSerine/threonine-protein kinase 242.7.11.10.446
4ysjADPCalmodulin-like domain protein kinase/0.446
5aaaVGHALK tyrosine kinase receptor2.7.10.10.446
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1pmv537Mitogen-activated protein kinase 102.7.11.240.445
2of4979Tyrosine-protein kinase Lck2.7.10.20.445
2pwlACPFibroblast growth factor receptor 2/0.445
2vx07X7Ephrin type-B receptor 42.7.10.10.445
2w1fL0FAurora kinase A2.7.11.10.445
3bhtMFRCyclin-dependent kinase 22.7.11.220.445
3blqATPCyclin-dependent kinase 92.7.11.220.445
3cgfJNFMitogen-activated protein kinase 102.7.11.240.445
3cukFADD-amino-acid oxidase1.4.3.30.445
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.445
3oibFDAPutative acyl-CoA dehydrogenase/0.445
3orlAGSSerine/threonine protein kinase/0.445
4anqVGHALK tyrosine kinase receptor2.7.10.10.445
4i4e1BQFocal adhesion kinase 12.7.10.20.445
4kin1M8Mitogen-activated protein kinase 14/0.445
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.445
4ohxADPProtein clpf-1/0.445
4s32ANPMitogen-activated protein kinase 12.7.11.240.445
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2aa3AP0L-lactate dehydrogenase/0.444
2ad5ADPCTP synthase/0.444
2eklNADD-3-phosphoglycerate dehydrogenase/0.444
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2pmlANPUncharacterized protein/0.444
3lqfNADGalactitol dehydrogenase/0.444
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.444
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4enhFVXCholesterol 24-hydroxylase/0.444
4joa3DKALK tyrosine kinase receptor2.7.10.10.444
5auvAGIDeath-associated protein kinase 12.7.11.10.444
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.443
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.443
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.443
1ykdCMPAdenylate cyclase/0.443
2bxnIDBSerum albumin/0.443
2c5nCK8Cyclin-dependent kinase 22.7.11.220.443
2d8aNADL-threonine 3-dehydrogenase/0.443
2gs7ANPEpidermal growth factor receptor2.7.10.10.443
2vgoAD5Aurora kinase B-A2.7.11.10.443
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.443
3d8vUD1Bifunctional protein GlmU/0.443
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.443
3flzFLZMitogen-activated protein kinase 14/0.443
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.443
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.443
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.443
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.443
4fv8E63Mitogen-activated protein kinase 12.7.11.240.443
4hgt15GCasein kinase I isoform delta2.7.11.10.443
4oauADP2-5A-dependent ribonuclease3.1.260.443
4s33ANPMitogen-activated protein kinase 12.7.11.240.443
5av2KMPDeath-associated protein kinase 12.7.11.10.443
1di8DTQCyclin-dependent kinase 22.7.11.220.442
1lj8NADMannitol dehydrogenase/0.442
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
2ok7FADFerredoxin--NADP reductase, apicoplast/0.442
2vx17X8Ephrin type-B receptor 42.7.10.10.442
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.442
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.442
3lltANPProtein serine/threonine kinase-1/0.442
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3oriAGSSerine/threonine protein kinase/0.442
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.442
4c3pACPAurora kinase A2.7.11.10.442
4yswFADXanthine dehydrogenase/oxidase/0.442
5ap57RODual specificity protein kinase TTK2.7.12.10.442
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.441
1tvoFRZMitogen-activated protein kinase 12.7.11.240.441
1u4dDBQActivated CDC42 kinase 1/0.441
3t2kFADSulfide-quinone reductase/0.441
3tdl11DSerum albumin/0.441
3tnwF18Cyclin-dependent kinase 22.7.11.220.441
3w33W19Epidermal growth factor receptor2.7.10.10.441
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.441
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.441
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.441
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4l9kEHFSerum albumin/0.441
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.441
1i59ANPChemotaxis protein CheA2.7.13.30.440
1oi9N20Cyclin-dependent kinase 22.7.11.220.440
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1v0pPVBCell division control protein 2 homolog2.7.11.220.440
1wvxBD4Death-associated protein kinase 12.7.11.10.440
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.440
2izrBRKCasein kinase I isoform gamma-32.7.11.10.440
2izsBRQCasein kinase I isoform gamma-32.7.11.10.440
2tpsTPSThiamine-phosphate synthase/0.440
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.440
2vwu7X1Ephrin type-B receptor 42.7.10.10.440
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.440
3bhy7CPDeath-associated protein kinase 3/0.440
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3pxkPXKFocal adhesion kinase 12.7.10.20.440
3sdkP3NProteasome subunit beta type-53.4.25.10.440
3sdkP3NProteasome subunit beta type-63.4.25.10.440
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.440
3u8w09JMitogen-activated protein kinase 14/0.440
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.440
4guvFADTetX family tetracycline inactivation enzyme/0.440
4m55NADUDP-glucuronic acid decarboxylase 14.1.1.350.440
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4nxvGDPMitochondrial dynamics protein MID51/0.440
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.440
4zseANPEpidermal growth factor receptor2.7.10.10.440
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.440