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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.11.000
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.761
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.751
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.708
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.669
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.642
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.636
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.633
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.611
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.606
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.601
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.599
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.595
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.593
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.591
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.583
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.581
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.580
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.579
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.579
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.579
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.578
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.577
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.574
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.572
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.572
2hog710Serine/threonine-protein kinase Chk12.7.11.10.571
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.571
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.570
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.569
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.569
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.568
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.568
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.566
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.564
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.564
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.564
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.563
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.563
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.561
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.558
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.558
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.558
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.556
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.554
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.554
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.553
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.552
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.552
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.552
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.551
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.550
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.549
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.547
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.545
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.544
3a62STURibosomal protein S6 kinase beta-12.7.11.10.544
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.543
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.542
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.542
1zys199Serine/threonine-protein kinase Chk12.7.11.10.540
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.540
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.540
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.538
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.535
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.535
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.534
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.534
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.534
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.532
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.532
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.532
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.531
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.530
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.529
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.528
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.528
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.527
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.525
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.525
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.524
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.523
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.522
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.522
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.520
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.519
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.518
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.518
3gu6ADPDeath-associated protein kinase 12.7.11.10.517
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.517
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.516
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.515
3gubGUBDeath-associated protein kinase 12.7.11.10.515
3zh8C58Protein kinase C iota type2.7.11.130.515
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.513
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.513
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.512
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.510
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.510
5auwQUEDeath-associated protein kinase 12.7.11.10.510
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.509
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.509
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.509
3sheI85MAP kinase-activated protein kinase 32.7.11.10.509
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.508
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.507
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.507
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.507
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.507
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.507
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.506
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.506
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.506
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.506
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.505
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.504
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.503
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.503
3gu83GUDeath-associated protein kinase 12.7.11.10.503
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.502
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.502
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.502
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.502
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.502
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.501
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.501
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.501
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.501
3i60E86Mitogen-activated protein kinase 12.7.11.240.500
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.498
2j0lANPFocal adhesion kinase 12.7.10.20.498
3c4xATPRhodopsin kinase/0.498
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.498
4gu610NFocal adhesion kinase 12.7.10.20.498
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.497
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.497
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.496
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.496
3t8oATPRhodopsin kinase/0.495
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.495
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.495
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.494
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.494
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.494
4ysjADPCalmodulin-like domain protein kinase/0.494
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.493
3eyhIZATyrosine-protein kinase JAK1/0.493
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.493
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.492
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.492
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
1u4dDBQActivated CDC42 kinase 1/0.491
1xjdSTUProtein kinase C theta type2.7.11.130.490
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.490
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.490
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.490
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.489
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.489
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.488
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.488
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.488
5auvAGIDeath-associated protein kinase 12.7.11.10.488
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.487
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.487
4i22IREEpidermal growth factor receptor2.7.10.10.487
2cn8DBQSerine/threonine-protein kinase Chk22.7.11.10.486
2j0m4STFocal adhesion kinase 12.7.10.20.486
4jia1K3Tyrosine-protein kinase JAK2/0.486
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.485
2xneASHAurora kinase A2.7.11.10.485
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.485
5e92ANPTGF-beta receptor type-22.7.11.300.485
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.484
5e8wSTUTGF-beta receptor type-12.7.11.300.484
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.483
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.483
2uzbC75Cyclin-dependent kinase 22.7.11.220.483
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.483
5av2KMPDeath-associated protein kinase 12.7.11.10.482
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
4f650S9Fibroblast growth factor receptor 1/0.481
4fod0UVALK tyrosine kinase receptor2.7.10.10.481
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.481
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.480
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.480
4yuqKS1Calmodulin-like domain protein kinase/0.480
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.479
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.479
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.478
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.478
3ggfGVDSerine/threonine-protein kinase 26/0.478
3zewSTUEphrin type-B receptor 42.7.10.10.478
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.478
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.478
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.478
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.477
2x1nX1NCyclin-dependent kinase 22.7.11.220.477
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.477
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.477
5auuLU2Death-associated protein kinase 12.7.11.10.477
1zrzBI1Protein kinase C iota type2.7.11.130.476
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.476
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.476
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.476
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.476
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
4iwd1JCHepatocyte growth factor receptor2.7.10.10.476
1ppm0P1Penicillopepsin-13.4.23.200.475
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.475
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.475
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.475
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.474
5av4GENDeath-associated protein kinase 12.7.11.10.474
1aq1STUCyclin-dependent kinase 22.7.11.220.473
1bxoPP7Penicillopepsin-13.4.23.200.473
3dfcANPDeath-associated protein kinase 12.7.11.10.473
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.473
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.473
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.472
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.472
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.472
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.472
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.472
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.472
2bfyH1NAurora kinase B-A2.7.11.10.471
2cchATPCyclin-dependent kinase 22.7.11.220.471
2dwbANPAurora kinase A2.7.11.10.471
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.471
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.471
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.470
3vf9477Tyrosine-protein kinase SYK2.7.10.20.470
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.470
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.469
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.469
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.469
1e9hINRCyclin-dependent kinase 22.7.11.220.468
2iw84SPCyclin-dependent kinase 22.7.11.220.468
2yn8STUEphrin type-B receptor 42.7.10.10.468
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.468
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.468
2j0k4STFocal adhesion kinase 12.7.10.20.467
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.467
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3w551FMMitogen-activated protein kinase 12.7.11.240.467
4eor4SPCyclin-dependent kinase 22.7.11.220.467
4wboANWRhodopsin kinase/0.467
5auxKMPDeath-associated protein kinase 12.7.11.10.467
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.466
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.466
4hvh19RTyrosine-protein kinase JAK32.7.10.20.466
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.466
1me6IVSPlasmepsin-23.4.23.390.465
1qmzATPCyclin-dependent kinase 22.7.11.220.465
2ejkSAHDiphthine synthase/0.465
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.465
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.465
4fmqANPMitogen-activated protein kinase 12.7.11.240.465
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.465
5e8xSTUTGF-beta receptor type-12.7.11.300.465
1jklANPDeath-associated protein kinase 12.7.11.10.464
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.464
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.464
1unlRRCCyclin-dependent-like kinase 52.7.11.10.463
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.463
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.463
1ol6ATPAurora kinase A2.7.11.10.462
1wvxBD4Death-associated protein kinase 12.7.11.10.462
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.462
2vd5BI8Myotonin-protein kinase2.7.11.10.462
2wihP48Cyclin-dependent kinase 22.7.11.220.462
2xikJ60Serine/threonine-protein kinase 252.7.11.10.462
3bhtMFRCyclin-dependent kinase 22.7.11.220.462
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.462
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.462
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.462
4brxKGWFocal adhesion kinase 12.7.10.20.462
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.462
4gk2L66Ephrin type-A receptor 32.7.10.10.462
4qmpDKISerine/threonine-protein kinase 242.7.11.10.462
4qmzB49Serine/threonine-protein kinase 242.7.11.10.462
1xelUPGUDP-glucose 4-epimerase5.1.3.20.461
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.461
3bqr4RBDeath-associated protein kinase 3/0.461
4hvi19STyrosine-protein kinase JAK32.7.10.20.461
1u54ACPActivated CDC42 kinase 1/0.460
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.460
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.460
2x9fX9FEphrin type-B receptor 42.7.10.10.460
3c4wATPRhodopsin kinase/0.460
3tucFPWTyrosine-protein kinase SYK2.7.10.20.460
3vs3VSETyrosine-protein kinase HCK2.7.10.20.460
4h3qANPMitogen-activated protein kinase 12.7.11.240.460
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
4y93746Tyrosine-protein kinase/0.460
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.460
1nzfUPGDNA beta-glucosyltransferase/0.459
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.459
2b7aIZATyrosine-protein kinase JAK2/0.459
2eufLQQCyclin-dependent kinase 62.7.11.220.459
2ijmADPFocal adhesion kinase 12.7.10.20.459
2p5fSAHDiphthine synthase/0.459
2vgoAD5Aurora kinase B-A2.7.11.10.459
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.459
4c02TAKActivin receptor type-12.7.11.300.459
4erkOLOMitogen-activated protein kinase 12.7.11.240.459
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.459
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.459
1nzdUPGDNA beta-glucosyltransferase/0.458
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.458
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.458
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.458
4c57FEFCyclin-G-associated kinase2.7.11.10.458
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.458
4fv6E57Mitogen-activated protein kinase 12.7.11.240.458
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.458
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.458
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.458
5e8ySTUTGF-beta receptor type-22.7.11.300.458
1p4fDRGDeath-associated protein kinase 12.7.11.10.457
2wedPP6Penicillopepsin-13.4.23.200.457
2y6o1N1Ephrin type-A receptor 42.7.10.10.457
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.457
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.457
4ix5ANPUncharacterized protein/0.457
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.457
5dr6SKEAurora kinase A2.7.11.10.457
1bwsNDPGDP-L-fucose synthase/0.456
2jkqVG8Focal adhesion kinase 12.7.10.20.456
2qo9ANPEphrin type-A receptor 32.7.10.10.456
2uzlC94Cyclin-dependent kinase 22.7.11.220.456
3c50ADPRhodopsin kinase/0.456
3s1dZIRCytokinin dehydrogenase 11.5.99.120.456
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.455
1lf3EH5Plasmepsin-23.4.23.390.455
1vjy460TGF-beta receptor type-12.7.11.300.455
2uzeC95Cyclin-dependent kinase 22.7.11.220.455
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.455
3pxkPXKFocal adhesion kinase 12.7.10.20.455
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.455
4ix6ADPUncharacterized protein/0.455
1oguST8Cyclin-dependent kinase 22.7.11.220.454
2hutSAHDiphthine synthase/0.454
2wxvWXVCyclin-dependent kinase 22.7.11.220.454
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.454
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.454
3tnwF18Cyclin-dependent kinase 22.7.11.220.454
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4fob0USALK tyrosine kinase receptor2.7.10.10.454
1h1r6CPCyclin-dependent kinase 22.7.11.220.453
2jkkBI9Focal adhesion kinase 12.7.10.20.453
2oji33AMitogen-activated protein kinase 12.7.11.240.453
3gu5ANPDeath-associated protein kinase 12.7.11.10.453
3hllI45Mitogen-activated protein kinase 14/0.453
3oom507Activin receptor type-12.7.11.300.453
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.453
4fx360KCyclin-dependent kinase 22.7.11.220.453
4xgxADPFAD:protein FMN transferase/0.453
4xlvACPInsulin receptor2.7.10.10.453
5dt3ATPAurora kinase A2.7.11.10.453
1c1dNAIPhenylalanine dehydrogenase/0.452
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.452
2ijmATPFocal adhesion kinase 12.7.10.20.452
2owkSAHDiphthine synthase/0.452
2vagV25Dual specificity protein kinase CLK12.7.12.10.452
3ctyFADProbable thioredoxin reductase/0.452
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.452
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.452
3nynSGVG protein-coupled receptor kinase 62.7.11.160.452
4btjATPTau-tubulin kinase 12.7.11.10.452
4fkv61KCyclin-dependent kinase 22.7.11.220.452
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.452
1h1s4SPCyclin-dependent kinase 22.7.11.220.451
1ir3ANPInsulin receptor2.7.10.10.451
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.451
2emuSAHDiphthine synthase/0.451
2owuSAHDiphthine synthase/0.451
2xlrFADPutative flavin-containing monooxygenase/0.451
2xvdAS6Ephrin type-B receptor 42.7.10.10.451
3lxiCAMCytochrome P450/0.451
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.451
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.451
4aacAAVMitogen-activated protein kinase 14/0.451
4fv9E71Mitogen-activated protein kinase 12.7.11.240.451
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.451
4j97ACPFibroblast growth factor receptor 2/0.451
5auzGENDeath-associated protein kinase 12.7.11.10.451
1fvv107Cyclin-dependent kinase 22.7.11.220.450
1iwiCAMCamphor 5-monooxygenase1.14.15.10.450
1pyePM1Cyclin-dependent kinase 22.7.11.220.450
1qy5NECEndoplasmin/0.450
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1t85CAMCamphor 5-monooxygenase1.14.15.10.450
2bkzSBCCyclin-dependent kinase 22.7.11.220.450
2ckeIQUDeath-associated protein kinase 2/0.450
2e15SAHDiphthine synthase/0.450
2in6839Wee1-like protein kinase2.7.10.20.450
2pwlACPFibroblast growth factor receptor 2/0.450
2wotZZGTGF-beta receptor type-12.7.11.300.450
3bi6396Wee1-like protein kinase2.7.10.20.450
3d84NDPDihydrofolate reductase1.5.1.30.450
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.450
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.450
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.450
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.450
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.449
2c5nCK8Cyclin-dependent kinase 22.7.11.220.449
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.449
4foc0UUALK tyrosine kinase receptor2.7.10.10.449
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.449
4lopSB4Mitogen-activated protein kinase 14/0.449
4loqSB4Mitogen-activated protein kinase 14/0.449
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.449
1oiyN41Cyclin-dependent kinase 22.7.11.220.448
2bhhRYUCyclin-dependent kinase 22.7.11.220.448
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.448
2vwy7X5Ephrin type-B receptor 42.7.10.10.448
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.448
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.448
3p67FMNPentaerythritol tetranitrate reductase/0.448
3pldF90Endothiapepsin3.4.23.220.448
3w32W32Epidermal growth factor receptor2.7.10.10.448
4fv8E63Mitogen-activated protein kinase 12.7.11.240.448
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.448
1gheACOAcetyltransferase2.3.10.447
1xe55FEPlasmepsin-23.4.23.390.447
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.447
2izrBRKCasein kinase I isoform gamma-32.7.11.10.447
2po7CHDFerrochelatase, mitochondrial4.99.1.10.447
2wecPP5Penicillopepsin-13.4.23.200.447
2y9qANPMitogen-activated protein kinase 12.7.11.240.447
3b895GP16S rRNA methylase/0.447
3raiX85Cyclin-dependent kinase 22.7.11.220.447
4c58824Cyclin-G-associated kinase2.7.11.10.447
4wsqKSAAP2-associated protein kinase 12.7.11.10.447
4y95746Tyrosine-protein kinase/0.447
5dr9SKEAurora kinase A2.7.11.10.447
1oirHDYCyclin-dependent kinase 22.7.11.220.446
1u3dFADCryptochrome-1/0.446
1yvj4STTyrosine-protein kinase JAK32.7.10.20.446
2acxANPG protein-coupled receptor kinase 62.7.11.160.446
2qblCAMCamphor 5-monooxygenase1.14.15.10.446
3bhy7CPDeath-associated protein kinase 3/0.446
3dxmN24Actin-related protein 3/0.446
3iok1P6Tyrosine-protein kinase JAK2/0.446
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.446
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.446
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.446
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1c6yMK1Protease/0.445
1gih1PUCyclin-dependent kinase 22.7.11.220.445
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.445
1vyw292Cyclin-dependent kinase 22.7.11.220.445
2xnbY8LCyclin-dependent kinase 22.7.11.220.445
3oibFDAPutative acyl-CoA dehydrogenase/0.445
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.445
4dpuAGSMevalonate diphosphate decarboxylase/0.445
4du82P0Mevalonate diphosphate decarboxylase/0.445
4ek610KCyclin-dependent kinase 22.7.11.220.445
4fkg4CKCyclin-dependent kinase 22.7.11.220.445
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.445
4nj32KDCyclin-dependent kinase 22.7.11.220.445
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.444
2dsgSAHDiphthine synthase/0.444
2v7a627Tyrosine-protein kinase ABL12.7.10.20.444
3uyt0CKCasein kinase I isoform delta2.7.11.10.444
3vf80JETyrosine-protein kinase SYK2.7.10.20.444
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.444
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.444
4o0wADNAurora kinase A2.7.11.10.444
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.444
1e7qNAPGDP-L-fucose synthase/0.443
1g5sI17Cyclin-dependent kinase 22.7.11.220.443
1oiuN76Cyclin-dependent kinase 22.7.11.220.443
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.443
2ccu2D9Heat shock protein HSP 90-alpha/0.443
2e7rSAHDiphthine synthase/0.443
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.443
2hcdBIVVitamin D3 receptor A/0.443
2qbmCAMCamphor 5-monooxygenase1.14.15.10.443
3emg685Tyrosine-protein kinase SYK2.7.10.20.443
3hx4ANPCalmodulin-domain protein kinase 1/0.443
3lpkZ76Beta-secretase 13.4.23.460.443
3wmxNADNAD dependent epimerase/dehydratase/0.443
3zdu38RCyclin-dependent kinase-like 32.7.11.220.443
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4f081RSTyrosine-protein kinase JAK2/0.443
4hge15VTyrosine-protein kinase JAK2/0.443
4ia3BIVVitamin D3 receptor A/0.443
4utdACPAurora kinase A2.7.11.10.443
5av3KMPDeath-associated protein kinase 12.7.11.10.443
1ke9LS5Cyclin-dependent kinase 22.7.11.220.442
2e17SAHDiphthine synthase/0.442
2egsSAHDiphthine synthase/0.442
2huxSAHDiphthine synthase/0.442
2vwz7X6Ephrin type-B receptor 42.7.10.10.442
2xmyCDKCyclin-dependent kinase 22.7.11.220.442
3dogNNNCyclin-dependent kinase 22.7.11.220.442
3hmm855TGF-beta receptor type-12.7.11.300.442
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.442
3pj8404Cyclin-dependent kinase 22.7.11.220.442
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.442
4btjADPTau-tubulin kinase 12.7.11.10.442
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.442
4fyn0VETyrosine-protein kinase SYK2.7.10.20.442
4gmy0X5Tyrosine-protein kinase JAK2/0.442
4hvg19QTyrosine-protein kinase JAK32.7.10.20.442
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.442
4nk92K5Fibroblast growth factor receptor 1/0.442
1o76CAMCamphor 5-monooxygenase1.14.15.10.441
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.441
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.441
2ed5SAHDiphthine synthase/0.441
2qboCAMCamphor 5-monooxygenase1.14.15.10.441
3fwfCAMCamphor 5-monooxygenase1.14.15.10.441
3wrmCAMCamphor 5-monooxygenase1.14.15.10.441
4d58BI9Focal adhesion kinase 12.7.10.20.441
4gk3L87Ephrin type-A receptor 32.7.10.10.441
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.441
1eh4IC1Casein kinase I homolog 12.7.11.10.440
1iwjCAMCamphor 5-monooxygenase1.14.15.10.440
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.440
2byi2DDHeat shock protein HSP 90-alpha/0.440
2dv3SAHDiphthine synthase/0.440
2dv5SAHDiphthine synthase/0.440
2dv7SAHDiphthine synthase/0.440
2ejjSAHDiphthine synthase/0.440
2itpAEEEpidermal growth factor receptor2.7.10.10.440
2pmlANPUncharacterized protein/0.440
3b9lAZZSerum albumin/0.440
3cisATPUniversal stress protein Rv2623/0.440
3eljGS7Mitogen-activated protein kinase 82.7.11.240.440
3kb1ADPIron-sulfur cluster carrier protein/0.440
3qc9ADPRhodopsin kinase/0.440
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3s2pPMUCyclin-dependent kinase 22.7.11.220.440
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.440
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4jr7GNPCasein kinase II subunit alpha2.7.11.10.440
4klaCHDFerrochelatase, mitochondrial4.99.1.10.440
5a3cNADSIR2 family protein/0.440
5dn3ATPAurora kinase A2.7.11.10.440