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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1zosMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1zosMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/1.000
1y6qTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.634
3eeiMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.634
3dp9BIG5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.612
1y6rMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.610
4x24TDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.596
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.576
4wkbTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.569
4bmzMTAAminodeoxyfutalosine nucleosidase/0.529
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.515
7catNDPCatalase1.11.1.60.502
3tkyN7I(Iso)eugenol O-methyltransferase2.1.1.1460.500
1xf0ASDAldo-keto reductase family 1 member C3/0.499
3ns2PYVAbscisic acid receptor PYL2/0.499
4ixc1JDGlucokinase2.7.1.20.496
1pqc444Oxysterols receptor LXR-beta/0.492
2pg0FADAcyl-CoA dehydrogenase/0.491
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.491
4ixd1HVIntegrin alpha-L/0.490
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.490
2vbpVB1Isopenicillin N synthase1.21.3.10.489
3s41S41Glucokinase2.7.1.20.489
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.487
3njoPYVAbscisic acid receptor PYR1/0.486
2hzqSTRApolipoprotein D/0.485
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.485
3vf60H6Glucokinase2.7.1.20.485
4dbs0HVAldo-keto reductase family 1 member C3/0.484
1ej3CZHAequorin-2/0.483
1ygjRMCPyridoxal kinase2.7.1.350.483
3ghvGHCDihydrofolate reductase1.5.1.30.483
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.483
2cbqTH2Neocarzinostatin/0.482
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.481
2ibwCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.480
8catNDPCatalase1.11.1.60.480
1qiqACCIsopenicillin N synthase1.21.3.10.479
3imxB84Glucokinase2.7.1.20.479
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.479
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.479
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.478
3d7zGK5Mitogen-activated protein kinase 14/0.477
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.476
3zoiM2WIsopenicillin N synthase1.21.3.10.476
4ap1NAPSteroid monooxygenase/0.476
4dvi2IWTankyrase-12.4.2.300.475
1ndzFR5Adenosine deaminase3.5.4.40.474
2xtbKRMAdenosine kinase, putative/0.474
3e5aVX6Aurora kinase A2.7.11.10.474
1blzACVIsopenicillin N synthase1.21.3.10.473
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.473
1ihiIU5Aldo-keto reductase family 1 member C2/0.473
1ry0PG2Aldo-keto reductase family 1 member C3/0.473
1trkTPPTransketolase 12.2.1.10.473
2dhfDZFDihydrofolate reductase1.5.1.30.473
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.473
4dhyS41Glucokinase2.7.1.20.473
2yee2ECHeat shock protein HSP 90-alpha/0.472
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.472
4pnmNU1Tankyrase-22.4.2.300.472
1hb1OCVIsopenicillin N synthase1.21.3.10.471
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
3bi6396Wee1-like protein kinase2.7.10.20.471
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.471
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
1synF89Thymidylate synthase/0.470
1w29TS16,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.470
2vcmM11Isopenicillin N synthase1.21.3.10.470
3itzP66Mitogen-activated protein kinase 14/0.470
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.470
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.470
4kd79DRDihydrofolate reductase1.5.1.30.470
4kxjP34Nucleoprotein/0.470
4qzuRTLRetinol-binding protein 2/0.470
1disBDMDihydrofolate reductase1.5.1.30.469
3w5uFADFerredoxin/0.469
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.468
2gvcFADThiol-specific monooxygenase1.14.130.468
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.468
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
4jtrIBPAldo-keto reductase family 1 member C2/0.468
1umlFR4Adenosine deaminase3.5.4.40.467
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
2z3uCRRCytochrome P450/0.467
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
2bxoOPBSerum albumin/0.466
3eon341Glutaryl-CoA dehydrogenase/0.466
3wv9FEGHmd co-occurring protein HcgE/0.466
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.465
1ohjCOPDihydrofolate reductase1.5.1.30.465
1u1cBAUUridine phosphorylase2.4.2.30.465
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.465
3up3XCAaceDAF-12/0.465
1gaeNADGlyceraldehyde-3-phosphate dehydrogenase A/0.464
1jf2CZHObelin/0.464
1wxyFRKAdenosine deaminase3.5.4.40.464
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.464
3zkyWT4Isopenicillin N synthase1.21.3.10.464
1fkwPURAdenosine deaminase3.5.4.40.463
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.463
1o6qR17Squalene--hopene cyclase4.2.1.1290.463
1toiHCIAspartate aminotransferase2.6.1.10.463
2d2gDZZPhosphotriesterase/0.463
2y6fM9FIsopenicillin N synthase1.21.3.10.463
4zj8SUVOrexin receptor type 1/0.463
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.462
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1h36R88Squalene--hopene cyclase4.2.1.1290.462
1mvtDTMDihydrofolate reductase1.5.1.30.462
3ojgHL4Phosphotriesterase/0.462
3p2oNADBifunctional protein FolD/0.462
3up0D7SaceDAF-12/0.462
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.462
4j3lAJ5Tankyrase-22.4.2.300.462
4pnrG18Tankyrase-22.4.2.300.462
4psbGA3Cytokinin-specific binding protein/0.462
1njjORXOrnithine decarboxylase/0.461
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.461
3p9tTCLRepressor/0.461
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.461
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.461
5cmx0G6Prothrombin3.4.21.50.461
5iua6DXAdenosine receptor A2a/0.461
1nm6L86Prothrombin3.4.21.50.460
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.460
1oc1ASVIsopenicillin N synthase1.21.3.10.460
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.460
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.460
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
2wi72KLHeat shock protein HSP 90-alpha/0.460
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.460
4aoaIK2Beta-phenylalanine transaminase2.6.10.460
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.460
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.460
4twnB96Ephrin type-A receptor 32.7.10.10.460
5iu4ZMAAdenosine receptor A2a/0.460
5uviZMAAdenosine receptor A2a/0.460
1d3dBZTProthrombin3.4.21.50.459
1dr4HBIDihydrofolate reductase1.5.1.30.459
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.459
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.459
3qpg3QPAspartate aminotransferase2.6.1.10.459
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.459
1s3uTQDDihydrofolate reductase1.5.1.30.458
1txtCAAHMG-CoA synthase/0.458
1uy8PU5Heat shock protein HSP 90-alpha/0.458
2bfmTOPPteridine reductase 11.5.1.330.458
2c3p1TPPyruvate synthase/0.458
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.458
3eanFADThioredoxin reductase 1, cytoplasmic1.8.1.90.458
3elePLPAminotransferase/0.458
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.458
3zkuHCVIsopenicillin N synthase1.21.3.10.458
4hqvQEIQueuine tRNA-ribosyltransferase2.4.2.290.458
4jxxATPGlutamine--tRNA ligase6.1.1.180.458
4phlPILPhosphodiesterase/0.458
5agyGTBTau class glutathione S-transferase/0.458
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.457
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.457
1xkqNDPUncharacterized protein/0.457
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.457
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
3htjETEbrA repressor/0.457
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.457
3vo2FADFerredoxin--NADP reductase/0.457
3zc3FADFerredoxin--NADP reductase1.18.1.20.457
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.457
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.457
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.290.457
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.457
4pl9ADPEthylene receptor 1/0.457
5k2aZMAAdenosine receptor A2a/0.457
1hb3SCVIsopenicillin N synthase1.21.3.10.456
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
2bu9HFVIsopenicillin N synthase1.21.3.10.456
2pksG44Prothrombin3.4.21.50.456
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.456
3l3rOAGDihydrofolate reductase1.5.1.30.456
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.456
3qri919Tyrosine-protein kinase ABL12.7.10.20.456
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
4bqyFNTEgl nine homolog 1/0.456
1fkxPRHAdenosine deaminase3.5.4.40.455
1h35R01Squalene--hopene cyclase4.2.1.1290.455
1opbRETRetinol-binding protein 2/0.455
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.455
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.455
2vbdV10Isopenicillin N synthase1.21.3.10.455
2w3aTOPDihydrofolate reductase1.5.1.30.455
2yatEEUEstrogen receptor/0.455
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.455
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.455
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.455
3lfcZ86Mitogen-activated protein kinase 14/0.455
3nxvD2FDihydrofolate reductase1.5.1.30.455
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.455
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4iwv1J9Glucokinase2.7.1.20.455
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.455
1d6w00RProthrombin3.4.21.50.454
1dr3TAPDihydrofolate reductase1.5.1.30.454
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.454
1xm1GAHProthrombin3.4.21.50.454
1zq5E04Aldo-keto reductase family 1 member C3/0.454
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.454
3emlZMAAdenosine receptor A2a/0.454
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.453
1jwtBLIProthrombin3.4.21.50.453
1kzuRG1Light-harvesting protein B-800/850 alpha chain/0.453
1kzuRG1Light-harvesting protein B-800/850 beta chain/0.453
1nbuPH2Dihydroneopterin aldolase/0.453
1t4v14AProthrombin3.4.21.50.453
1yhjR6CPyridoxal kinase2.7.1.350.453
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.453
3nglNAPBifunctional protein FolD/0.453
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.453
4kfjFOLDihydrofolate reductase1.5.1.30.453
5a4wQCTGlutathione S-transferase F22.5.1.180.453
3qakUKAAdenosine receptor A2a/0.453
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.452
1drfFOLDihydrofolate reductase1.5.1.30.452
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.452
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.452
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.452
2npxNADNADH peroxidase1.11.1.10.452
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.452
2x20PIDPeridinin-chlorophyll a-binding protein 1, chloroplastic/0.452
3elm24FCollagenase 33.4.240.452
3gieACPSensor histidine kinase DesK2.7.13.30.452
3qh23NMThiazole tautomerase/0.452
3u3o3QVSulfotransferase 1A12.8.2.10.452
3uweVJJAldo-keto reductase family 1 member C3/0.452
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.452
4o701QKBromodomain-containing protein 4/0.452
5kf2ACOPredicted acetyltransferase/0.452
5k2cZMAAdenosine receptor A2a/0.452
1zprCB3Thymidylate synthase/0.451
2adaHPRAdenosine deaminase3.5.4.40.451
2fzdTOLAldose reductase1.1.1.210.451
3a1l2CCCytochrome P450/0.451
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3gkjHC3Niemann-Pick C1 protein/0.451
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.451
3pg3DG7Mitogen-activated protein kinase 14/0.451
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.451
4b4w9L9Bifunctional protein FolD/0.451
4l091URTankyrase-22.4.2.300.451
4qij1HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.451
4uugPXGBranched-chain amino acid aminotransferase, putative/0.451
4zasTYDCalS13/0.451
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.451
1fmjRTLRetinol dehydratase/0.450
1kdmDHTSex hormone-binding globulin/0.450
1p8dCO1Oxysterols receptor LXR-beta/0.450
2a9y26AAdenosine kinase2.7.1.200.450
2wmdZZ0NmrA-like family domain-containing protein 1/0.450
3e92G6AMitogen-activated protein kinase 14/0.450
3nxtD2EDihydrofolate reductase1.5.1.30.450
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.450
3zeiAWHO-acetylserine sulfhydrylase/0.450
4l33F70Tankyrase-22.4.2.300.450
1euyQSIGlutamine--tRNA ligase6.1.1.180.449
1qjfACSIsopenicillin N synthase1.21.3.10.449
1ro98BRcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.449
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.449
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2r5nTPPTransketolase 1/0.449
2rc6NAPFerredoxin--NADP reductase/0.449
2w3mFOLDihydrofolate reductase1.5.1.30.449
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2x2rADPKinesin-like protein KIF11/0.449
2zc922UProthrombin3.4.21.50.449
3b1dPLSBetaC-S lyase/0.449
3nu03TUDihydrofolate reductase1.5.1.30.449
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.449
3ug8IMNAldo-keto reductase family 1 member C3/0.449
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.449
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.449
4hyf1AKTankyrase-22.4.2.300.449
4jq3ZOMAldo-keto reductase family 1 member C2/0.449
4jtqFLPAldo-keto reductase family 1 member C2/0.449
4kebFOLDihydrofolate reductase1.5.1.30.449
4y6nUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.449
5cc9DDFDihydrofolate reductase1.5.1.30.449
1ae8AZLProthrombin3.4.21.50.448
1ah3TOLAldose reductase1.1.1.210.448
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1uydPU8Heat shock protein HSP 90-alpha/0.448
1wl4COAAcetyl-CoA acetyltransferase, cytosolic2.3.1.90.448
2flhZEACytokinin-specific binding protein/0.448
2h7jH7JCathepsin S3.4.22.270.448
2ykiYKIHeat shock protein HSP 90-alpha/0.448
2zseACPPantothenate kinase2.7.1.330.448
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.448
3lt1FT2Enoyl-ACP reductase/0.448
4xba5GPAprataxin-like protein30.448
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.448
5kf9ACOPredicted acetyltransferase/0.448
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.447
2bbf344Queuine tRNA-ribosyltransferase2.4.2.290.447
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.447
2v59LZKBiotin carboxylase6.3.4.140.447
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.447
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3qdd94MHeat shock protein HSP 90-alpha/0.447
4n1gCEIObelin/0.447
4stdBFSScytalone dehydratase4.2.1.940.447
4zqcF6FTryptophan synthase alpha chain/0.447
1e2nRCAThymidine kinase/0.446
1jtuLYBThymidylate synthase/0.446
1o6rR19Squalene--hopene cyclase4.2.1.1290.446
1qrsATPGlutamine--tRNA ligase6.1.1.180.446
1wuuANPGalactokinase2.7.1.60.446
1y5wNEZQueuine tRNA-ribosyltransferase2.4.2.290.446
1ybgTAVUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
1ypgUIRProthrombin3.4.21.50.446
1z5uCMPClass B acid phosphatase/0.446
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.446
2bt4CA23-dehydroquinate dehydratase4.2.1.100.446
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.446
2qg2A91Heat shock protein HSP 90-alpha/0.446
2qzrS79Queuine tRNA-ribosyltransferase2.4.2.290.446
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.446
2zb1GK4Mitogen-activated protein kinase 14/0.446
3ds6A17Mitogen-activated protein kinase 14/0.446
3fnhJPJEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4bj9UHBTankyrase-22.4.2.300.446
4ddrMMVDihydrofolate reductase1.5.1.30.446
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.446
1p33MTXPteridine reductase 11.5.1.330.445
1w06W05Isopenicillin N synthase1.21.3.10.445
2ydoADNAdenosine receptor A2a/0.445
3fhxPLPPyridoxal kinase2.7.1.350.445
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.445
3pm9FADPutative oxidoreductase/0.445
3q3cNADNAD-dependent L-serine dehydrogenase/0.445
4jtrIZPAldo-keto reductase family 1 member C2/0.445
4kbn25UDihydrofolate reductase1.5.1.30.445
4m6l21VDihydrofolate reductase1.5.1.30.445
4m8hR4MRetinoic acid receptor RXR-alpha/0.445
5iu86DZAdenosine receptor A2a/0.445
3sn6P0GBeta-2 adrenergic receptor/0.445
1axwMTXThymidylate synthase/0.444
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.444
1j8uH4BPhenylalanine-4-hydroxylase1.14.16.10.444
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.444
1pq944BOxysterols receptor LXR-beta/0.444
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.444
1trgCB3Thymidylate synthase/0.444
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.444
2c42TPPPyruvate synthase/0.444
2jk6FADTrypanothione reductase/0.444
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2wzySQXSoluble acetylcholine receptor/0.444
2xlsFADPutative flavin-containing monooxygenase/0.444
2xvhFADPutative flavin-containing monooxygenase/0.444
2yk2YJWHeat shock protein HSP 90-alpha/0.444
3ghh2NFCD38 molecule/0.444
3ghwGHWDihydrofolate reductase1.5.1.30.444
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.444
3q7fED2Uncharacterized protein/0.444
4ag7COAGlucosamine 6-phosphate N-acetyltransferase/0.444
4b4vL34Bifunctional protein FolD/0.444
4buwF33Tankyrase-22.4.2.300.444
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.444
4fhd0TTSpore photoproduct lyase/0.444
4iw8KN3Estrogen receptor/0.444
4kzl20DTankyrase-22.4.2.300.444
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.443
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.443
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.443
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.443
1rdtL79Retinoic acid receptor RXR-alpha/0.443
1srfMTBStreptavidin/0.443
1w78PD8Dihydrofolate synthase/folylpolyglutamate synthase6.3.2.120.443
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.443
2bjsACVIsopenicillin N synthase1.21.3.10.443
2clfF6FTryptophan synthase alpha chain/0.443
2g78REACellular retinoic acid-binding protein 2/0.443
2v58LZJBiotin carboxylase6.3.4.140.443
2wu4HBPAcetylcholinesterase3.1.1.70.443
2zdv37UProthrombin3.4.21.50.443
3c3xNAPEugenol synthase 11.1.1.3180.443
3dzl3OCPhenazine biosynthesis protein A/B/0.443
3exnACOProbable acetyltransferase/0.443
3nwb659Catechol O-methyltransferase2.1.1.60.443
3ozsOZSCatechol O-methyltransferase2.1.1.60.443
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.443
3qwc98PProthrombin3.4.21.50.443
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.443
3w0hW12Vitamin D3 receptor/0.443
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.443
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4eh8IRGMitogen-activated protein kinase 14/0.443
4ez8DHFThymidylate synthase2.1.1.450.443
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.443
4kak06UDihydrofolate reductase1.5.1.30.443
4l4xNDPAmphI/0.443
4tjy3GNTankyrase-22.4.2.300.443
5c4iTPPOxalate oxidoreductase subunit alpha/0.443
5c4iTPPOxalate oxidoreductase subunit beta/0.443
5kgjACOPredicted acetyltransferase/0.443
5g53NECAdenosine receptor A2a/0.443
1ia3TQ5Dihydrofolate reductase1.5.1.30.442
1ia4TQ6Dihydrofolate reductase1.5.1.30.442
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.442
1uy9PU6Heat shock protein HSP 90-alpha/0.442
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.442
1w87FADFerredoxin--NADP reductase1.18.1.20.442
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2c97JCL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2iyaZIOOleandomycin glycosyltransferase/0.442
2r0pK2CPutative FAD-monooxygenase/0.442
2vz0D64Pteridine reductase/0.442
2wo7ASVIsopenicillin N synthase1.21.3.10.442
2zda32UProthrombin3.4.21.50.442
3aezGDPPantothenate kinase2.7.1.330.442
3d84NDPDihydrofolate reductase1.5.1.30.442
3e8xNAPBH1520 protein/0.442
3gkiCLRNiemann-Pick C1 protein/0.442
3hub469Mitogen-activated protein kinase 14/0.442
3k4551PDihydrofolate reductase1.5.1.30.442
3lfzADPUncharacterized protein MJ1225/0.442
3nxoD2BDihydrofolate reductase1.5.1.30.442
3nxrD2DDihydrofolate reductase1.5.1.30.442
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.442
4az3S35Lysosomal protective protein3.4.16.50.442
4cdmFO1Deoxyribodipyrimidine photolyase/0.442
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.442
4jq1NPSAldo-keto reductase family 1 member C2/0.442
4ku5DCC3-oxoacyl-[ACP] synthase III/0.442
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.442
5a4vQUEGlutathione S-transferase F22.5.1.180.442
5c1gGDUHisto-blood group ABO system transferase/0.442
5d7oAR6NAD-dependent protein deacetylase sirtuin-23.5.10.442
5iubCLRAdenosine receptor A2a/0.442
1hfqMOTDihydrofolate reductase1.5.1.30.441
1jtqLY3Thymidylate synthase/0.441
1kzjCB3Thymidylate synthase/0.441
1o5rFR9Adenosine deaminase3.5.4.40.441
1r8qAFBCytohesin-2/0.441
1r8qAFBADP-ribosylation factor 1/0.441
1uycPU7Heat shock protein HSP 90-alpha/0.441
2b58COADiamine acetyltransferase 1/0.441
2c3oTPPPyruvate synthase/0.441
2fzjDH3Dihydrofolate reductase1.5.1.30.441
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
3hv3R49Mitogen-activated protein kinase 14/0.441
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.441
3iej599Cathepsin S3.4.22.270.441
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.441
4b6s2HN3-dehydroquinate dehydratase4.2.1.100.441
4bb3KKAIsopenicillin N synthase1.21.3.10.441
4fa30SLAldo-keto reductase family 1 member C3/0.441
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4kfj1R0Dihydrofolate reductase1.5.1.30.441
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
4l8vNAPInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.441
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1a8t061Metallo-beta-lactamase type 2/0.440
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.440
1hfrMOTDihydrofolate reductase1.5.1.30.440
1lhuESTSex hormone-binding globulin/0.440
1ndyFR3Adenosine deaminase3.5.4.40.440
1oytFSNProthrombin3.4.21.50.440
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1z8962PAldose reductase1.1.1.210.440
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2bdyUNBProthrombin3.4.21.50.440
2ociTYCValacyclovir hydrolase3.10.440
2zzaFOLDihydrofolate reductase/0.440
3ed1GA3Gibberellin receptor GID1/0.440
3fpkFADFerredoxin-NADP reductase/0.440
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
3gncQQQGlutaryl-CoA dehydrogenase/0.440
3h1vTK1Glucokinase2.7.1.20.440
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.440
4blwSAHRibosomal RNA large subunit methyltransferase J/0.440
4c3yFAD3-ketosteroid dehydrogenase/0.440
4g95OAGDihydrofolate reductase1.5.1.30.440
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.440
4hx519VCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
4jln18VDeoxycytidine kinase2.7.1.740.440
4zvlFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
4zwpM44Xaa-Pro dipeptidase3.4.13.90.440
5k2bZMAAdenosine receptor A2a/0.440