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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ungALHCyclin-dependent-like kinase 52.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1ungALHCyclin-dependent-like kinase 52.7.11.11.000
4bcpT3CCyclin-dependent kinase 22.7.11.220.535
3rmf20ZCyclin-dependent kinase 22.7.11.220.526
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.525
1e9hINRCyclin-dependent kinase 22.7.11.220.524
1oi9N20Cyclin-dependent kinase 22.7.11.220.524
3r7iX9ICyclin-dependent kinase 22.7.11.220.522
2f2cAP9Cyclin-dependent kinase 62.7.11.220.519
3rm618ZCyclin-dependent kinase 22.7.11.220.517
3tnwF18Cyclin-dependent kinase 22.7.11.220.517
3qxoX65Cyclin-dependent kinase 22.7.11.220.516
2i40BLZCyclin-dependent kinase 22.7.11.220.515
3ezrEZRCyclin-dependent kinase 22.7.11.220.515
4qmzB49Serine/threonine-protein kinase 242.7.11.10.511
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.509
3rni21ZCyclin-dependent kinase 22.7.11.220.509
2iw84SPCyclin-dependent kinase 22.7.11.220.507
1oiyN41Cyclin-dependent kinase 22.7.11.220.505
3s2pPMUCyclin-dependent kinase 22.7.11.220.505
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.505
2bhhRYUCyclin-dependent kinase 22.7.11.220.504
3pj8404Cyclin-dependent kinase 22.7.11.220.504
3sqq99ZCyclin-dependent kinase 22.7.11.220.504
5cvhADPCasein kinase II subunit alpha2.7.11.10.504
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.503
3r7eX88Cyclin-dependent kinase 22.7.11.220.503
4eomATPCyclin-dependent kinase 22.7.11.220.503
1ke9LS5Cyclin-dependent kinase 22.7.11.220.502
1unlRRCCyclin-dependent-like kinase 52.7.11.10.502
4bcnT9NCyclin-dependent kinase 22.7.11.220.501
4eok4SPCyclin-dependent kinase 22.7.11.220.501
2wxvWXVCyclin-dependent kinase 22.7.11.220.500
3ddqRRCCyclin-dependent kinase 22.7.11.220.500
3qu0X40Cyclin-dependent kinase 22.7.11.220.499
3r1sX73Cyclin-dependent kinase 22.7.11.220.499
1fvt106Cyclin-dependent kinase 22.7.11.220.498
3bhtMFRCyclin-dependent kinase 22.7.11.220.498
3qziX72Cyclin-dependent kinase 22.7.11.220.497
3rm719ZCyclin-dependent kinase 22.7.11.220.496
1v1k3FPCyclin-dependent kinase 22.7.11.220.495
2cchATPCyclin-dependent kinase 22.7.11.220.495
2iw94SPCyclin-dependent kinase 22.7.11.220.495
3dogNNNCyclin-dependent kinase 22.7.11.220.495
4fkr45KCyclin-dependent kinase 22.7.11.220.495
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.495
1gih1PUCyclin-dependent kinase 22.7.11.220.494
3r8zZ63Cyclin-dependent kinase 22.7.11.220.494
3ral04ZCyclin-dependent kinase 22.7.11.220.494
1h1r6CPCyclin-dependent kinase 22.7.11.220.493
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.493
2w06FRVCyclin-dependent kinase 22.7.11.220.493
2wihP48Cyclin-dependent kinase 22.7.11.220.493
3rjc06ZCyclin-dependent kinase 22.7.11.220.493
1oguST8Cyclin-dependent kinase 22.7.11.220.492
3ql8X01Cyclin-dependent kinase 22.7.11.220.492
3qtqX35Cyclin-dependent kinase 22.7.11.220.491
3qzhX69Cyclin-dependent kinase 22.7.11.220.491
4cfnJYMCyclin-dependent kinase 22.7.11.220.490
4bcoT6QCyclin-dependent kinase 22.7.11.220.489
4f700STCyclin-dependent kinase 82.7.11.220.488
4jqeANPCasein kinase II subunit alpha2.7.11.10.488
4nj32KDCyclin-dependent kinase 22.7.11.220.488
1aq1STUCyclin-dependent kinase 22.7.11.220.487
2b55D31Cyclin-dependent kinase 22.7.11.220.487
3s1h56ZCyclin-dependent kinase 22.7.11.220.487
3unj0BXCyclin-dependent kinase 22.7.11.220.487
3ddpRC8Cyclin-dependent kinase 22.7.11.220.486
1pkdUCNCyclin-dependent kinase 22.7.11.220.485
3r8pZ46Cyclin-dependent kinase 22.7.11.220.485
4acm7YGCyclin-dependent kinase 22.7.11.220.485
1ke6LS2Cyclin-dependent kinase 22.7.11.220.484
2wpa889Cyclin-dependent kinase 22.7.11.220.484
3rk708ZCyclin-dependent kinase 22.7.11.220.484
1unhIXMCyclin-dependent-like kinase 52.7.11.10.483
2izt23DCasein kinase I isoform gamma-32.7.11.10.482
2r3p3SCCyclin-dependent kinase 22.7.11.220.482
3rak03ZCyclin-dependent kinase 22.7.11.220.482
3roy22ZCyclin-dependent kinase 22.7.11.220.482
1di8DTQCyclin-dependent kinase 22.7.11.220.481
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.481
3rk507ZCyclin-dependent kinase 22.7.11.220.481
4eor4SPCyclin-dependent kinase 22.7.11.220.481
4erwSTUCyclin-dependent kinase 22.7.11.220.481
1r78FMDCyclin-dependent kinase 22.7.11.220.480
1vyw292Cyclin-dependent kinase 22.7.11.220.480
2b52D42Cyclin-dependent kinase 22.7.11.220.480
3be9P04Casein kinase II subunit alpha2.7.11.10.480
3nga3NGCasein kinase II subunit alpha2.7.11.10.480
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.480
3r7yZ04Cyclin-dependent kinase 22.7.11.220.480
4ez30S0Cyclin-dependent kinase 22.7.11.220.480
1oirHDYCyclin-dependent kinase 22.7.11.220.479
2btrU73Cyclin-dependent kinase 22.7.11.220.479
2duv371Cyclin-dependent kinase 22.7.11.220.479
2pvnP63Casein kinase II subunit alpha2.7.11.10.479
2x1nX1NCyclin-dependent kinase 22.7.11.220.479
3r6xX84Cyclin-dependent kinase 22.7.11.220.479
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.478
1h1s4SPCyclin-dependent kinase 22.7.11.220.478
3qtzX42Cyclin-dependent kinase 22.7.11.220.478
3qwkX62Cyclin-dependent kinase 22.7.11.220.478
4qmySTUSerine/threonine-protein kinase 242.7.11.10.478
2c6tDT5Cyclin-dependent kinase 22.7.11.220.477
3lfnA27Cyclin-dependent kinase 22.7.11.220.477
3q9yTXQCasein kinase II subunit alpha2.7.11.10.477
3rk909ZCyclin-dependent kinase 22.7.11.220.477
3q9xEMOCasein kinase II subunit alpha2.7.11.10.476
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.476
4fkw62KCyclin-dependent kinase 22.7.11.220.476
4j97ACPFibroblast growth factor receptor 2/0.476
2fvdLIACyclin-dependent kinase 22.7.11.220.475
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.475
3mb601ICasein kinase II subunit alpha2.7.11.10.475
3wblPDYCyclin-dependent kinase 22.7.11.220.475
4ia3BIVVitamin D3 receptor A/0.475
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.475
3r9dX6BCyclin-dependent kinase 22.7.11.220.474
4grb0XGCasein kinase II subunit alpha2.7.11.10.474
4gub0Y4Casein kinase II subunit alpha2.7.11.10.474
1h1q2A6Cyclin-dependent kinase 22.7.11.220.473
2a4lRRCCyclin-dependent kinase 22.7.11.220.473
3r1yX76Cyclin-dependent kinase 22.7.11.220.473
4dgo0JWCasein kinase II subunit alpha2.7.11.10.473
4fkv61KCyclin-dependent kinase 22.7.11.220.473
1bwsNDPGDP-L-fucose synthase/0.472
2uzeC95Cyclin-dependent kinase 22.7.11.220.472
3c4xATPRhodopsin kinase/0.472
3fz1B98Cyclin-dependent kinase 22.7.11.220.472
3qrtX14Cyclin-dependent kinase 22.7.11.220.472
1p2a5BNCyclin-dependent kinase 22.7.11.220.471
1w0xOLOCyclin-dependent kinase 22.7.11.220.471
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.471
3a4vNADNDP-sugar epimerase/0.471
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.471
3lfsA07Cyclin-dependent kinase 22.7.11.220.471
3uli1N3Cyclin-dependent kinase 22.7.11.220.471
5e8wSTUTGF-beta receptor type-12.7.11.300.471
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.470
2x7gPVBSRSF protein kinase 22.7.11.10.470
3qtrX36Cyclin-dependent kinase 22.7.11.220.470
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4bcqTJFCyclin-dependent kinase 22.7.11.220.470
4eooATPCyclin-dependent kinase 22.7.11.220.470
4fx360KCyclin-dependent kinase 22.7.11.220.470
4gk2L66Ephrin type-A receptor 32.7.10.10.470
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.470
1pyePM1Cyclin-dependent kinase 22.7.11.220.469
3qqkX02Cyclin-dependent kinase 22.7.11.220.469
3r7vZ02Cyclin-dependent kinase 22.7.11.220.469
3s0o50ZCyclin-dependent kinase 22.7.11.220.469
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.469
4qnaX11Serine/threonine-protein kinase 242.7.11.10.469
5a9sNAPPutative dehydrogenase/0.469
2c5nCK8Cyclin-dependent kinase 22.7.11.220.468
2vttLZDCyclin-dependent kinase 22.7.11.220.468
3lfqA28Cyclin-dependent kinase 22.7.11.220.468
3my5RFZCyclin-dependent kinase 22.7.11.220.468
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.468
3zmmF9JTyrosine-protein kinase JAK2/0.468
4eoi1ROCyclin-dependent kinase 22.7.11.220.468
1d2sDHTSex hormone-binding globulin/0.467
2c4g514Cyclin-dependent kinase 22.7.11.220.467
2uznC96Cyclin-dependent kinase 22.7.11.220.467
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.467
3r28XA0Cyclin-dependent kinase 22.7.11.220.467
3vt5YI2Vitamin D3 receptor/0.467
1oiuN76Cyclin-dependent kinase 22.7.11.220.466
2hcdBIVVitamin D3 receptor A/0.466
2vwz7X6Ephrin type-B receptor 42.7.10.10.466
2wipP49Cyclin-dependent kinase 22.7.11.220.466
3qzgX67Cyclin-dependent kinase 22.7.11.220.466
3r7uX96Cyclin-dependent kinase 22.7.11.220.466
3r8lZ30Cyclin-dependent kinase 22.7.11.220.466
1jpaANPEphrin type-B receptor 22.7.10.10.465
2a0cCK9Cyclin-dependent kinase 22.7.11.220.465
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.465
3p8zSAHGenome polyprotein2.1.1.560.465
4bchT7ZCyclin-dependent kinase 92.7.11.220.465
5fwnNAPPutative dehydrogenase/0.465
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.464
2r3lSCWCyclin-dependent kinase 22.7.11.220.464
2rhrEMOPutative ketoacyl reductase1.3.10.464
2uzlC94Cyclin-dependent kinase 22.7.11.220.464
3qqfX07Cyclin-dependent kinase 22.7.11.220.464
4mwhATPCasein kinase II subunit alpha2.7.11.10.464
5cu6ATPCasein kinase II subunit alpha2.7.11.10.464
1iyzNDPProbable quinone oxidoreductase/0.463
1m2qMNXCasein kinase II subunit alpha2.7.11.10.463
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.463
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.463
2qo9ANPEphrin type-A receptor 32.7.10.10.463
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.463
4dfrMTXDihydrofolate reductase1.5.1.30.463
4ek816KCyclin-dependent kinase 22.7.11.220.463
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.463
1gy3ATPCyclin-dependent kinase 22.7.11.220.462
1pxmCK5Cyclin-dependent kinase 22.7.11.220.462
2bfyH1NAurora kinase B-A2.7.11.10.462
2henADPEphrin type-B receptor 22.7.10.10.462
2jn3JN3Fatty acid-binding protein, liver/0.462
2vthLZ2Cyclin-dependent kinase 22.7.11.220.462
3hmm855TGF-beta receptor type-12.7.11.300.462
3r1qX75Cyclin-dependent kinase 22.7.11.220.462
3rkb12ZCyclin-dependent kinase 22.7.11.220.462
1gii1PUCyclin-dependent kinase 22.7.11.220.461
1gqtACPRibokinase/0.461
1ykr628Cyclin-dependent kinase 22.7.11.220.461
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.461
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.461
2w71L23Biotin carboxylase6.3.4.140.461
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.461
4jr7GNPCasein kinase II subunit alpha2.7.11.10.461
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.461
4q71FADBifunctional protein PutA/0.461
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.460
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2wotZZGTGF-beta receptor type-12.7.11.300.460
3iggEFQCyclin-dependent kinase 22.7.11.220.460
3umw596Serine/threonine-protein kinase pim-12.7.11.10.460
1dm2HMDCyclin-dependent kinase 22.7.11.220.459
2qoqANPEphrin type-A receptor 32.7.10.10.459
2r3mSCXCyclin-dependent kinase 22.7.11.220.459
2uzdC85Cyclin-dependent kinase 22.7.11.220.459
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
3ezvEZVCyclin-dependent kinase 22.7.11.220.459
3r73X87Cyclin-dependent kinase 22.7.11.220.459
3r9hZ67Cyclin-dependent kinase 22.7.11.220.459
4anmWULCasein kinase II subunit alpha2.7.11.10.459
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4dgnLU2Casein kinase II subunit alpha2.7.11.10.459
4eop1ROCyclin-dependent kinase 22.7.11.220.459
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.459
1qvnFRIInterleukin-2/0.458
2w1hL0FCyclin-dependent kinase 22.7.11.220.458
3qtxX43Cyclin-dependent kinase 22.7.11.220.458
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.458
4fki09KCyclin-dependent kinase 22.7.11.220.458
1fvv107Cyclin-dependent kinase 22.7.11.220.457
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.457
2w1fL0FAurora kinase A2.7.11.10.457
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4l4dCAMCamphor 5-monooxygenase1.14.15.10.457
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.457
4ure1PSCyclohexanol dehydrogenase/0.457
1t85CAMCamphor 5-monooxygenase1.14.15.10.456
1urwI1PCyclin-dependent kinase 22.7.11.220.456
1v0oINRCell division control protein 2 homolog2.7.11.220.456
2p5uNADUDP-glucose 4-epimerase/0.456
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.456
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.456
2vx17X8Ephrin type-B receptor 42.7.10.10.456
2z97CAMCamphor 5-monooxygenase1.14.15.10.456
2zdt46CMitogen-activated protein kinase 102.7.11.240.456
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.456
3vt7VDXVitamin D3 receptor/0.456
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4eos1ROCyclin-dependent kinase 22.7.11.220.456
4fkg4CKCyclin-dependent kinase 22.7.11.220.456
1gij2PUCyclin-dependent kinase 22.7.11.220.455
1h1pCMGCyclin-dependent kinase 22.7.11.220.455
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.455
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
2xnbY8LCyclin-dependent kinase 22.7.11.220.455
2zbaZBATrichothecene 3-O-acetyltransferase/0.455
3ac1KZITyrosine-protein kinase Lck2.7.10.20.455
3hl7I47Mitogen-activated protein kinase 14/0.455
3q9zTXQCasein kinase II subunit alpha2.7.11.10.455
4btjADPTau-tubulin kinase 12.7.11.10.455
4ead0NPThymidine phosphorylase2.4.2.40.455
4fkj11KCyclin-dependent kinase 22.7.11.220.455
4mv8ACPBiotin carboxylase6.3.4.140.455
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
1h63FMNPentaerythritol tetranitrate reductase/0.454
1zx1CB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.454
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.454
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.454
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.454
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.454
2pvyACPFibroblast growth factor receptor 2/0.454
2v59LZKBiotin carboxylase6.3.4.140.454
2vcmM11Isopenicillin N synthase1.21.3.10.454
3blrCPBCyclin-dependent kinase 92.7.11.220.454
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.454
3cgoJNOMitogen-activated protein kinase 102.7.11.240.454
3koo24DBifunctional epoxide hydrolase 23.3.2.100.454
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.454
1ke7LS3Cyclin-dependent kinase 22.7.11.220.453
1vyzN5BCyclin-dependent kinase 22.7.11.220.453
1ykdCMPAdenylate cyclase/0.453
2j0k4STFocal adhesion kinase 12.7.10.20.453
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.453
3p62FMNPentaerythritol tetranitrate reductase/0.453
4eol1ROCyclin-dependent kinase 22.7.11.220.453
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.453
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1db1VDXVitamin D3 receptor/0.452
1dyhDZFDihydrofolate reductase1.5.1.30.452
1nvtNAPShikimate dehydrogenase (NADP(+))/0.452
1phgMYTCamphor 5-monooxygenase1.14.15.10.452
1pxoCK7Cyclin-dependent kinase 22.7.11.220.452
1wbpADPSRSF protein kinase 12.7.11.10.452
2vx07X7Ephrin type-B receptor 42.7.10.10.452
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.452
3atzFMNProstaglandin F2a synthase/0.452
3r9oZ71Cyclin-dependent kinase 22.7.11.220.452
3vrwYS5Vitamin D3 receptor/0.452
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.452
4cdmFO1Deoxyribodipyrimidine photolyase/0.452
4e4m0NHTyrosine-protein kinase JAK2/0.452
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.452
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1f28UMPThymidylate synthase2.1.1.450.451
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1pjcNADAlanine dehydrogenase/0.451
1py5PY1TGF-beta receptor type-12.7.11.300.451
2bkzSBCCyclin-dependent kinase 22.7.11.220.451
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
2excJNKMitogen-activated protein kinase 102.7.11.240.451
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.451
3csdEMOPutative ketoacyl reductase1.3.10.451
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.451
4lyn1YGCyclin-dependent kinase 22.7.11.220.451
4qmpDKISerine/threonine-protein kinase 242.7.11.10.451
5cshATPCasein kinase II subunit alpha2.7.11.10.451
1eh4IC1Casein kinase I homolog 12.7.11.10.450
1rfuADPPyridoxal kinase2.7.1.350.450
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.450
2izrBRKCasein kinase I isoform gamma-32.7.11.10.450
2of4979Tyrosine-protein kinase Lck2.7.10.20.450
2pvlP55Casein kinase II subunit alpha2.7.11.10.450
2w17I19Cyclin-dependent kinase 22.7.11.220.450
3c11GDMATP-dependent molecular chaperone HSP82/0.450
3ig7EFPCyclin-dependent kinase 22.7.11.220.450
3lqfNADGalactitol dehydrogenase/0.450
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.450
3qtwX3ACyclin-dependent kinase 22.7.11.220.450
4fkt48KCyclin-dependent kinase 22.7.11.220.450
4gk4L90Ephrin type-A receptor 32.7.10.10.450
4looSB4Mitogen-activated protein kinase 14/0.450
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.449
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.449
2pmnK51Protein kinase 7/0.449
2wouZZFTGF-beta receptor type-12.7.11.300.449
3blqATPCyclin-dependent kinase 92.7.11.220.449
3p74FMNPentaerythritol tetranitrate reductase/0.449
3s1dZIRCytokinin dehydrogenase 11.5.99.120.449
4bgh3I6Cyclin-dependent kinase 22.7.11.220.449
4lopSB4Mitogen-activated protein kinase 14/0.449
4ogrADNCyclin-dependent kinase 92.7.11.220.449
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
4xwtU5PRibonuclease J/0.449
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.449
1zrzBI1Protein kinase C iota type2.7.11.130.448
3inxJZCHeat shock protein HSP 90-alpha/0.448
3p8iFMNPentaerythritol tetranitrate reductase/0.448
3u8w09JMitogen-activated protein kinase 14/0.448
3vrvYSDVitamin D3 receptor/0.448
3zep1NXTyrosine-protein kinase JAK32.7.10.20.448
4c02TAKActivin receptor type-12.7.11.300.448
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.448
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.448
4mgiCMPRap guanine nucleotide exchange factor 4/0.448
4xivACPChemotaxis protein CheA2.7.13.30.448
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
5c8d5ADProbable transcriptional regulator/0.448
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
1ke8LS4Cyclin-dependent kinase 22.7.11.220.447
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.447
2c6iDT1Cyclin-dependent kinase 22.7.11.220.447
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.447
2pvrANPCasein kinase II subunit alpha2.7.11.10.447
2qo7ANPEphrin type-A receptor 32.7.10.10.447
2r3kSCQCyclin-dependent kinase 22.7.11.220.447
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.447
2vwy7X5Ephrin type-B receptor 42.7.10.10.447
3pe6ZYHMonoglyceride lipase/0.447
3qtuX44Cyclin-dependent kinase 22.7.11.220.447
3raiX85Cyclin-dependent kinase 22.7.11.220.447
3sw418KCyclin-dependent kinase 22.7.11.220.447
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.447
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4fi1ATPCasein kinase II subunit alpha2.7.11.10.447
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4qmlANPSerine/threonine-protein kinase 242.7.11.10.447
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.446
1yw2PGJMitogen-activated protein kinase 14/0.446
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.446
2ev9NAPShikimate dehydrogenase (NADP(+))/0.446
2ghlLIBMitogen-activated protein kinase 14/0.446
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.446
2xikJ60Serine/threonine-protein kinase 252.7.11.10.446
3bheBZNGag-Pol polyprotein3.4.23.160.446
3d84NDPDihydrofolate reductase1.5.1.30.446
3gwfNAPCyclohexanone monooxygenase/0.446
3l8sBFFMitogen-activated protein kinase 14/0.446
3qlsNDPDihydrofolate reductase1.5.1.30.446
3t2zFADSulfide-quinone reductase/0.446
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.446
4g1z0VPVitamin D3 receptor A/0.446
4i8vBHFCytochrome P450 1A11.14.14.10.446
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.446
4iteTEYVitamin D3 receptor/0.446
4nb6444Nuclear receptor ROR-gamma/0.446
4y8wSTRSteroid 21-hydroxylase/0.446
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
1cqp803Integrin alpha-L/0.445
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.445
1ra3MTXDihydrofolate reductase1.5.1.30.445
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2izsBRQCasein kinase I isoform gamma-32.7.11.10.445
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.445
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.445
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.445
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.445
3cgeCOACoenzyme A disulfide reductase/0.445
3kf7L9GMitogen-activated protein kinase 14/0.445
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.445
3nj0PYVAbscisic acid receptor PYL2/0.445
3vg9ZMAAdenosine receptor A2a/0.445
3vt8YI3Vitamin D3 receptor/0.445
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.445
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.445
4kd11QKCyclin-dependent kinase 22.7.11.220.445
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.445
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.445
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.445
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.445
5iu86DZAdenosine receptor A2a/0.445
1bygSTUTyrosine-protein kinase CSK/0.444
1dhiMTXDihydrofolate reductase1.5.1.30.444
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1lf3EH5Plasmepsin-23.4.23.390.444
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.444
2hw2RFPRifampin ADP-ribosyl transferase/0.444
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.444
2v58LZJBiotin carboxylase6.3.4.140.444
2vagV25Dual specificity protein kinase CLK12.7.12.10.444
2zaxCAMCamphor 5-monooxygenase1.14.15.10.444
3a7jADPSerine/threonine-protein kinase 242.7.11.10.444
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4ek610KCyclin-dependent kinase 22.7.11.220.444
4f7l0SOCyclin-dependent kinase 82.7.11.220.444
4fkq42KCyclin-dependent kinase 22.7.11.220.444
4fob0USALK tyrosine kinase receptor2.7.10.10.444
4kbk1QGCasein kinase I isoform delta2.7.11.10.444
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.444
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.444
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1rx8NAPDihydrofolate reductase1.5.1.30.443
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.443
1vyrFMNPentaerythritol tetranitrate reductase/0.443
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.443
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.443
3a7hATPSerine/threonine-protein kinase 242.7.11.10.443
3c50ADPRhodopsin kinase/0.443
3cgdCOACoenzyme A disulfide reductase/0.443
3f03FMNPentaerythritol tetranitrate reductase/0.443
3fwjCAMCamphor 5-monooxygenase1.14.15.10.443
3nszANPCasein kinase II subunit alpha2.7.11.10.443
3pe13NGCasein kinase II subunit alpha2.7.11.10.443
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
3t2kFADSulfide-quinone reductase/0.443
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.443
3unk0BYCyclin-dependent kinase 22.7.11.220.443
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.443
4er6AW2Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.443
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4g160VMCasein kinase I isoform gamma-32.7.11.10.443
1dhjMTXDihydrofolate reductase1.5.1.30.442
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1ie8KH1Vitamin D3 receptor/0.442
1ikvEFZGag-Pol polyprotein2.7.7.490.442
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
1om1IQACasein kinase II subunit alpha2.7.11.10.442
1qmzATPCyclin-dependent kinase 22.7.11.220.442
1rkhVD2Vitamin D3 receptor/0.442
2chlDKICasein kinase I isoform gamma-32.7.11.10.442
2dwbANPAurora kinase A2.7.11.10.442
3a783EVVitamin D3 receptor/0.442
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.442
3o8tBMUMitogen-activated protein kinase 14/0.442
3oafOAGDihydrofolate reductase1.5.1.30.442
3zdu38RCyclin-dependent kinase-like 32.7.11.220.442
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.442
4ix6ADPUncharacterized protein/0.442
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.442
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.442
4ruoBIVVitamin D3 receptor A/0.442
1dawANPCasein kinase II subunit alpha2.7.11.10.441
1dr3TAPDihydrofolate reductase1.5.1.30.441
1h51FMNPentaerythritol tetranitrate reductase/0.441
1iwjCAMCamphor 5-monooxygenase1.14.15.10.441
1oiqHDUCyclin-dependent kinase 22.7.11.220.441
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.441
2hc4VDXVitamin D3 receptor A/0.441
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
3cgcCOACoenzyme A disulfide reductase/0.441
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3nr4PYVAbscisic acid receptor PYL2/0.441
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3pxyJWSCyclin-dependent kinase 22.7.11.220.441
3rpo24ZCyclin-dependent kinase 22.7.11.220.441
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4a6rTA8Probable aminotransferase/0.441
4btmF8ETau-tubulin kinase 12.7.11.10.441
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.441
4g1y0VOVitamin D3 receptor A/0.441
4nka2K7Fibroblast growth factor receptor 1/0.441
4rrfA3SThreonine--tRNA ligase6.1.1.30.441
5e8xSTUTGF-beta receptor type-12.7.11.300.441
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1lp4ANPCasein kinase II subunit alpha2.7.11.10.440
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2b7aIZATyrosine-protein kinase JAK2/0.440
2c5yMTWCyclin-dependent kinase 22.7.11.220.440
2c6o4SPCyclin-dependent kinase 22.7.11.220.440
2hbhXE4Vitamin D3 receptor A/0.440
2qbmCAMCamphor 5-monooxygenase1.14.15.10.440
2uzbC75Cyclin-dependent kinase 22.7.11.220.440
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.440
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.440
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.440
3fhxPLPPyridoxal kinase2.7.1.350.440
3mtfA3FActivin receptor type-12.7.11.300.440
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.440
3ttjJBIMitogen-activated protein kinase 102.7.11.240.440
3w5rLOAVitamin D3 receptor/0.440
4cp4CAMCamphor 5-monooxygenase1.14.15.10.440
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.440
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.440
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.440
4lfiGNPCasein kinase II subunit alpha2.7.11.10.440
4q72FADBifunctional protein PutA/0.440
4q73FADBifunctional protein PutA/0.440
4wboANWRhodopsin kinase/0.440
5iua6DXAdenosine receptor A2a/0.440