sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4zdb | CAA | 3,2-trans-enoyl-CoA isomerase | 5.3.3.8 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4zdb | CAA | 3,2-trans-enoyl-CoA isomerase | 5.3.3.8 | 1.000 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.542 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.535 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.507 | |
| 4zdc | CO8 | 3,2-trans-enoyl-CoA isomerase | 5.3.3.8 | 0.507 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.502 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.502 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.494 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.494 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.490 | |
| 1zdw | FLV | Prenyltransferase | / | 0.490 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.490 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.489 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.488 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.488 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.488 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.487 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.485 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.485 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.485 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.484 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.484 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 1r2j | FAD | FkbI | / | 0.482 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.482 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.480 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.479 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.479 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.478 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.478 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.478 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.477 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.477 | |
| 3nhr | RZW | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.476 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.475 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.475 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.474 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.473 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.473 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.472 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.472 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.472 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.472 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.470 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.470 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.470 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.470 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.470 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.470 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.470 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.470 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.470 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.470 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 4dkb | DUN | Deoxyuridine triphosphatase, putative | / | 0.470 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.470 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.469 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.469 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.468 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.468 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.468 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.468 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.467 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.467 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.467 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.466 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.466 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.466 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.466 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.466 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.465 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.464 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.464 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.464 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.464 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.464 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1dub | CAA | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.463 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.463 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.463 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.463 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.463 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.463 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.463 | |
| 1aj8 | COA | Citrate synthase | / | 0.462 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.462 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.462 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 3zcb | ATP | Adenosine monophosphate-protein transferase VbhT | 2.7.7.n1 | 0.462 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.462 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 2h12 | CMX | Citrate synthase | / | 0.461 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 4egn | TWO | Cytochrome P450 | / | 0.461 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.461 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.461 | |
| 1eio | GCH | Gastrotropin | / | 0.460 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.460 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2ejk | SAH | Diphthine synthase | / | 0.460 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.460 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.460 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.460 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.460 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.460 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.460 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.460 | |
| 5fl3 | ADP | Pili retraction protein PilT | / | 0.460 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.459 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.459 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.459 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.459 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.459 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.458 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.458 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.458 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.458 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.458 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.458 | |
| 4o28 | 1QS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.458 | |
| 1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.457 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2o21 | 43B | Apoptosis regulator Bcl-2 | / | 0.457 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.457 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4d9f | DCS | D-cysteine desulfhydrase | / | 0.457 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.457 | |
| 4q8p | CKR | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.457 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.456 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.456 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.456 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.456 | |
| 4irn | FAD | AnaB | / | 0.456 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.456 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 4rrm | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.456 | |
| 12gs | 0HH | Glutathione S-transferase P | 2.5.1.18 | 0.455 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.455 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.455 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.455 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.455 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.455 | |
| 2ydf | IO3 | Serum albumin | / | 0.455 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.455 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.455 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.455 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.455 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.455 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.455 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.455 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.455 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.455 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.455 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.454 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.454 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.454 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.454 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 2zzc | NAP | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.454 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.454 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 4m8e | 29V | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.453 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.453 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.453 | |
| 1t0i | FMN | NAD(P)H-dependent FMN reductase LOT6 | / | 0.453 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.453 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.453 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.453 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.453 | |
| 3hzi | ATP | Serine/threonine-protein kinase toxin HipA | / | 0.453 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.453 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 4boe | CLR | Japanin | / | 0.453 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.453 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.453 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.453 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.453 | |
| 4y6g | F6F | Tryptophan synthase alpha chain | / | 0.453 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.452 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.452 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.452 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.452 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.452 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.452 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.452 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.451 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.451 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.451 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.451 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.451 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.451 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.451 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.451 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.450 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.450 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1ptj | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.450 | |
| 1xef | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.450 | |
| 2emr | SAH | Diphthine synthase | / | 0.450 | |
| 2nr4 | FMN | Conserved protein | / | 0.450 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.450 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.450 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.450 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.450 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.450 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.450 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.449 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.449 | |
| 1uhh | CZP | Aequorin-2 | / | 0.449 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.449 | |
| 2c9e | PID | Peridinin-chlorophyll a protein, high-salt form | / | 0.449 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.449 | |
| 2pcm | SAH | Diphthine synthase | / | 0.449 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.449 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.449 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3f6s | FMN | Flavodoxin | / | 0.449 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.449 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.449 | |
| 4l9q | 9TP | Serum albumin | / | 0.449 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.449 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.449 | |
| 4xr9 | TMP | CalS8 | / | 0.449 | |
| 4y9u | FAD | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1axw | MTX | Thymidylate synthase | / | 0.448 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.448 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.448 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2egl | SAH | Diphthine synthase | / | 0.448 | |
| 2qzr | S79 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.448 | |
| 2wpw | ACO | Orf14 | / | 0.448 | |
| 2zwv | SAH | Probable ribosomal RNA small subunit methyltransferase | / | 0.448 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.448 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3p9t | TCL | Repressor | / | 0.448 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.448 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.448 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.448 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.448 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.448 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.447 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.447 | |
| 1fml | RTL | Retinol dehydratase | / | 0.447 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.447 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.447 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.447 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.447 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.447 | |
| 2pnu | ENM | Androgen receptor | / | 0.447 | |
| 2r0g | 7CK | Putative FAD-monooxygenase | / | 0.447 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.447 | |
| 2yat | EEU | Estrogen receptor | / | 0.447 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.447 | |
| 3mde | CO8 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.447 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.447 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.447 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.447 | |
| 4hcy | 0YN | Transketolase | / | 0.447 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.447 | |
| 4m8h | R4M | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.446 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.446 | |
| 1j7l | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.446 | |
| 1jum | BER | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.446 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.446 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.446 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.446 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 3f90 | FMN | Flavodoxin | / | 0.446 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.446 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.446 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.446 | |
| 4kqq | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.446 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.446 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1dtp | APU | Diphtheria toxin | / | 0.445 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.445 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.445 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.445 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.445 | |
| 2gtk | 208 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.445 | |
| 3bnk | FMN | Flavoredoxin | / | 0.445 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.445 | |
| 3dge | ADP | Sensor histidine kinase | / | 0.445 | |
| 3fbu | COA | Acetyltransferase, GNAT family | / | 0.445 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.445 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.445 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 3tle | GSU | Microcin C7 self-immunity protein MccF | / | 0.445 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.445 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4gh1 | 0WX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.445 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.444 | |
| 2ejz | SAH | Diphthine synthase | / | 0.444 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.444 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.444 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.444 | |
| 2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.444 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.444 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.444 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.444 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.444 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.444 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.444 | |
| 4y0k | NAP | AntE | / | 0.444 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.444 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.444 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.444 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.443 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.443 | |
| 1zaf | 789 | Estrogen receptor beta | / | 0.443 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.443 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.443 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.443 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.443 | |
| 3dsr | ADP | V-type ATP synthase beta chain | / | 0.443 | |
| 3rpn | GTX | Glutathione S-transferase kappa 1 | 2.5.1.18 | 0.443 | |
| 3tgu | WF3 | Cytochrome b | / | 0.443 | |
| 3up3 | XCA | aceDAF-12 | / | 0.443 | |
| 3v1u | HXC | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.443 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.443 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.443 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.443 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 4rr8 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.443 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.443 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.443 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.442 | |
| 1vce | SAH | Diphthine synthase | / | 0.442 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.442 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.442 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 2tdm | UMP | Thymidylate synthase | / | 0.442 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.442 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.442 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.442 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3ojw | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.442 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.442 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 4qjq | OTR | Lactoperoxidase | / | 0.442 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.442 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.441 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
| 2ga9 | AGS | Poly(A) polymerase catalytic subunit | 2.7.7.19 | 0.441 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.441 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2wgg | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.441 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.441 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.441 | |
| 3syt | NAD | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.441 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.441 | |
| 4dyp | 0MS | Nucleoprotein | / | 0.441 | |
| 4flp | JQ1 | Bromodomain testis-specific protein | / | 0.441 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.440 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.440 | |
| 1p16 | GTP | mRNA-capping enzyme subunit alpha | 2.7.7.50 | 0.440 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.440 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.440 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2dsi | SAH | Diphthine synthase | / | 0.440 | |
| 2dxv | SAH | Diphthine synthase | / | 0.440 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2owg | SAH | Diphthine synthase | / | 0.440 | |
| 2p6k | SAH | Diphthine synthase | / | 0.440 | |
| 2p9d | SAH | Diphthine synthase | / | 0.440 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.440 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.440 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 2y05 | RAL | Prostaglandin reductase 1 | / | 0.440 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.440 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.440 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.440 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.440 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.440 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.440 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.440 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.440 | |
| 5bn3 | ADP | NEQ263 | / | 0.440 | |
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.440 |