Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
4uco | IWH | DNA ligase |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
4uco | IWH | DNA ligase | / | 1.000 | |
5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.521 | |
5bn3 | ADP | NEQ263 | / | 0.521 | |
1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.519 | |
3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.513 | |
4to2 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.502 | |
4qg0 | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.501 | |
4to1 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.499 | |
1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.498 | |
1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.495 | |
1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.495 | |
2jdc | CAO | Probable acetyltransferase | / | 0.492 | |
4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.488 | |
4boe | CLR | Japanin | / | 0.487 | |
4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.487 | |
2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.486 | |
2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.485 | |
3pn1 | IVH | DNA ligase | / | 0.485 | |
4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.485 | |
4hej | 14D | Thymidylate kinase | / | 0.485 | |
4fsa | 0V3 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.484 | |
4jq1 | NPS | Aldo-keto reductase family 1 member C2 | / | 0.484 | |
3ele | PLP | Aminotransferase | / | 0.482 | |
2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.481 | |
1lrm | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.480 | |
1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.480 | |
3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.480 | |
3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.480 | |
3s41 | S41 | Glucokinase | 2.7.1.2 | 0.480 | |
3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.480 | |
3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.480 | |
4lwx | MU2 | Ribosome inactivating protein | / | 0.480 | |
4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.479 | |
4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.479 | |
5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.479 | |
1z5u | CMP | Class B acid phosphatase | / | 0.478 | |
4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.478 | |
5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.478 | |
2avx | HTF | Regulatory protein SdiA | / | 0.477 | |
2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.477 | |
3l6j | Z90 | Alr2278 protein | / | 0.477 | |
4b2g | V1N | Uncharacterized protein | / | 0.477 | |
3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.476 | |
2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.475 | |
1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.474 | |
4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.474 | |
1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.473 | |
1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.473 | |
1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.473 | |
4rxs | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.473 | |
4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.473 | |
5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.473 | |
1dmw | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.472 | |
1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.472 | |
3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
5jr3 | 4MU | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.472 | |
1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.471 | |
1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.471 | |
4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.471 | |
4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.471 | |
4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.471 | |
7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.471 | |
3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.470 | |
3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.470 | |
4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
4rxp | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.470 | |
3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.469 | |
3n9j | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.469 | |
4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.469 | |
1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
4qg1 | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.468 | |
1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.467 | |
1ej3 | CZH | Aequorin-2 | / | 0.467 | |
2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
3rj0 | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.467 | |
3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.467 | |
4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.466 | |
3hfb | ML4 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.466 | |
3szf | DCQ | Sulfide-quinone reductase | / | 0.466 | |
4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.466 | |
5bn4 | ANP | V-type ATP synthase alpha chain | / | 0.466 | |
1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.465 | |
3cas | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
2r0p | K2C | Putative FAD-monooxygenase | / | 0.464 | |
3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.464 | |
3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.464 | |
1jf2 | CZH | Obelin | / | 0.463 | |
1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.463 | |
1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
3l2k | PXC | EhpF | / | 0.463 | |
3lzz | GDP | Uncharacterized protein | / | 0.463 | |
3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.462 | |
1i7l | ATP | Synapsin-2 | / | 0.462 | |
1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.462 | |
2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.462 | |
2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.462 | |
3e9s | TTT | Replicase polyprotein 1ab | 3.4.22 | 0.462 | |
3p9t | TCL | Repressor | / | 0.462 | |
4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.462 | |
4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.462 | |
4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.462 | |
4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.462 | |
4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.462 | |
2yg5 | FAD | Putrescine oxidase | / | 0.461 | |
3znr | NU9 | Histone deacetylase 7 | 3.5.1.98 | 0.461 | |
4gki | 0JN | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.461 | |
4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.461 | |
4lez | 1SY | Cyclic GMP-AMP synthase | / | 0.461 | |
4n1f | CZH | Obelin | / | 0.461 | |
4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.461 | |
1y5w | NEZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.460 | |
2bu5 | TF1 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.460 | |
2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.460 | |
4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.460 | |
4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.460 | |
4phl | PIL | Phosphodiesterase | / | 0.460 | |
1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.459 | |
1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.459 | |
1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.459 | |
2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.459 | |
2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.459 | |
2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.459 | |
2oaz | I96 | Methionine aminopeptidase 2 | / | 0.459 | |
3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.459 | |
3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.459 | |
4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.459 | |
4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.458 | |
1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.458 | |
2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.458 | |
2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.458 | |
3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.458 | |
3hf8 | ML0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.458 | |
3vhm | NPK | Avidin | / | 0.458 | |
4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.458 | |
4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.458 | |
4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.458 | |
1qv1 | CZH | Obelin | / | 0.457 | |
2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.457 | |
3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.457 | |
4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
4imf | SI3 | N-acetylneuraminate lyase | / | 0.457 | |
4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
1eko | I84 | Aldose reductase | 1.1.1.21 | 0.456 | |
1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.456 | |
1n0s | FLU | Bilin-binding protein | / | 0.456 | |
1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.456 | |
1y1r | ANU | Uridine phosphorylase | 2.4.2.3 | 0.456 | |
2zda | 32U | Prothrombin | 3.4.21.5 | 0.456 | |
3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.456 | |
3gki | CLR | Niemann-Pick C1 protein | / | 0.456 | |
3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.456 | |
3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
4iae | 1DX | Alr2278 protein | / | 0.456 | |
4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.456 | |
5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.456 | |
1odj | GMP | Purine nucleoside phosphorylase | / | 0.455 | |
2a4x | BLM | Mitomycin-binding protein | / | 0.455 | |
2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.455 | |
2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.455 | |
3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.455 | |
3n61 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.455 | |
4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.455 | |
4b6r | 3DQ | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.455 | |
4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.455 | |
1l8t | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.454 | |
1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.454 | |
1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.454 | |
1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.454 | |
2jj1 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.454 | |
2jj1 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
2nr4 | FMN | Conserved protein | / | 0.454 | |
3f6s | FMN | Flavodoxin | / | 0.454 | |
3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.454 | |
4d9f | DCS | D-cysteine desulfhydrase | / | 0.454 | |
4jqh | 1MF | Alr2278 protein | / | 0.454 | |
4nqg | CZH | Mitrocomin | / | 0.454 | |
4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.454 | |
1cjw | COT | Serotonin N-acetyltransferase | / | 0.453 | |
1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
1s2c | FLF | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
2ejz | SAH | Diphthine synthase | / | 0.453 | |
2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.453 | |
2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.453 | |
3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
3v0n | 4GW | Histo-blood group ABO system transferase | / | 0.453 | |
1jdz | FMB | Purine nucleoside phosphorylase | / | 0.452 | |
1qin | GIP | Lactoylglutathione lyase | 4.4.1.5 | 0.452 | |
1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.452 | |
1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.452 | |
1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
2z4w | 749 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.452 | |
3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.452 | |
3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.452 | |
3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.452 | |
4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.452 | |
4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
4jtp | ASC | Ribosome inactivating protein | / | 0.452 | |
4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.452 | |
5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.452 | |
1gt5 | BZQ | Odorant-binding protein | / | 0.451 | |
1i05 | LTL | Major urinary protein 6 | / | 0.451 | |
1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.451 | |
2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.451 | |
3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.451 | |
3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.451 | |
4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.451 | |
4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.451 | |
4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.451 | |
4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
4y1b | NAP | AntE | / | 0.451 | |
4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.451 | |
1je1 | GMP | Purine nucleoside phosphorylase | / | 0.450 | |
1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
2nm2 | NEU | Dihydroneopterin aldolase | / | 0.450 | |
2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.450 | |
3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
3i68 | J4Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.450 | |
3p2o | NAD | Bifunctional protein FolD | / | 0.450 | |
3sl2 | ATP | Sensor histidine kinase WalK | / | 0.450 | |
4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.450 | |
4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.450 | |
1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.449 | |
1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
1xp8 | AGS | Protein RecA | / | 0.449 | |
1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.449 | |
2c97 | JCL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
2uuk | 897 | Prothrombin | 3.4.21.5 | 0.449 | |
2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.449 | |
3q0v | LL4 | HTH-type transcriptional regulator EthR | / | 0.449 | |
4bqu | CLR | Japanin | / | 0.449 | |
4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.449 | |
4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.449 | |
4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.449 | |
5c1m | CLR | Mu-type opioid receptor | / | 0.449 | |
5e9e | ANP | Myosin heavy chain kinase A | 2.7.11.7 | 0.449 | |
1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.448 | |
1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.448 | |
1sl9 | CZH | Obelin | / | 0.448 | |
2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.448 | |
3bmq | AX5 | Pteridine reductase | / | 0.448 | |
3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.448 | |
3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.448 | |
5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.448 | |
6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.447 | |
1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.447 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.447 | |
3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.447 | |
3ocw | 3AM | Lipoprotein E | / | 0.447 | |
3ptz | UDX | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.447 | |
3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.447 | |
4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.447 | |
4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.447 | |
4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.446 | |
1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.446 | |
1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.446 | |
1k8z | IAG | Tryptophan synthase alpha chain | / | 0.446 | |
1kuy | COT | Serotonin N-acetyltransferase | / | 0.446 | |
1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
1swn | BTN | Streptavidin | / | 0.446 | |
1swp | BTN | Streptavidin | / | 0.446 | |
2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.446 | |
2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
2v57 | PRL | TetR family transcriptional regulator | / | 0.446 | |
2yg3 | FAD | Putrescine oxidase | / | 0.446 | |
2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.446 | |
3dsr | ADP | V-type ATP synthase beta chain | / | 0.446 | |
3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
3qwc | 98P | Prothrombin | 3.4.21.5 | 0.446 | |
4e37 | NDP | Catalase | 1.11.1.6 | 0.446 | |
4hh4 | SAH | CcbJ | / | 0.446 | |
4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.446 | |
4imu | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
4ise | 1FW | Glucokinase | 2.7.1.2 | 0.446 | |
4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.446 | |
4tny | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.446 | |
1cl2 | PPG | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.445 | |
1dp2 | LPB | Thiosulfate sulfurtransferase | / | 0.445 | |
1ppj | ANY | Cytochrome b | / | 0.445 | |
2bd0 | BIO | Sepiapterin reductase | / | 0.445 | |
2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.445 | |
2zym | ACX | Periplasmic binding protein | / | 0.445 | |
3axb | FAD | Putative oxidoreductase | / | 0.445 | |
3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.445 | |
3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.445 | |
3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
4ag9 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.445 | |
4bub | ADP | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase | / | 0.445 | |
4dyp | 0MS | Nucleoprotein | / | 0.445 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.445 | |
4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.445 | |
1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.444 | |
1lke | DOG | Bilin-binding protein | / | 0.444 | |
1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.444 | |
1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
1t48 | BB3 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.444 | |
1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.444 | |
1w7k | ADP | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.444 | |
1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.444 | |
2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.444 | |
2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.444 | |
2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.444 | |
2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.444 | |
2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
2zhq | 27U | Prothrombin | 3.4.21.5 | 0.444 | |
3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
3vhh | VHH | Avidin | / | 0.444 | |
3x02 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.444 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
4mry | CEI | Obelin | / | 0.444 | |
4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.444 | |
5bu2 | ADP | Uncharacterized protein | / | 0.444 | |
5d4v | YGP | Uncharacterized protein MJ0489 | / | 0.444 | |
7cat | NDP | Catalase | 1.11.1.6 | 0.444 | |
1ddt | APU | Diphtheria toxin | / | 0.443 | |
1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.443 | |
1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
1w19 | T2P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
1ype | UIP | Prothrombin | 3.4.21.5 | 0.443 | |
2c3p | 1TP | Pyruvate synthase | / | 0.443 | |
2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.443 | |
3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.443 | |
4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
4dhy | S41 | Glucokinase | 2.7.1.2 | 0.443 | |
4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
4s1i | PLP | Pyridoxal kinase, putative | / | 0.443 | |
4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.443 | |
1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
1ngs | TPP | Transketolase 1 | 2.2.1.1 | 0.442 | |
1rs6 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
1thn | ADP | Anti-sigma F factor | / | 0.442 | |
1ve7 | 4NP | Acylamino-acid-releasing enzyme | 3.4.19.1 | 0.442 | |
1vi0 | DCC | Fatty acid metabolism regulator protein | / | 0.442 | |
1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.442 | |
1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
2hwu | URI | Uridine phosphorylase | 2.4.2.3 | 0.442 | |
2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.442 | |
2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
3cv6 | HXS | Aldo-keto reductase family 1 member C21 | / | 0.442 | |
3dr7 | GPD | GDP-perosamine synthase | / | 0.442 | |
3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.442 | |
3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
3t0k | DCQ | Sulfide-quinone reductase | / | 0.442 | |
3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.442 | |
4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.442 | |
4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.441 | |
1s36 | CEI | Obelin | / | 0.441 | |
1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.441 | |
2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.441 | |
2zhf | 49U | Prothrombin | 3.4.21.5 | 0.441 | |
2zre | AGS | Protein RecA | / | 0.441 | |
3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.441 | |
4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.441 | |
4rtb | SAM | Putative thiazole biosynthesis protein ThiH | / | 0.441 | |
5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.441 | |
1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
1kyy | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
1lel | BH7 | Avidin | / | 0.440 | |
1nbh | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.440 | |
1uhj | CZB | Aequorin-2 | / | 0.440 | |
1upw | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.440 | |
2gqn | BLP | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.440 | |
2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.440 | |
2oat | PFM | Ornithine aminotransferase, mitochondrial | 2.6.1.13 | 0.440 | |
2ohj | FMN | Type A flavoprotein FprA | 1 | 0.440 | |
2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.440 | |
3c1o | NAP | Eugenol synthase | / | 0.440 | |
3fow | IMH | Purine nucleoside phosphorylase | / | 0.440 | |
3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.440 | |
4kyh | ZST | Lactoylglutathione lyase | 4.4.1.5 | 0.440 |