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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4eetFMNPhototropin-22.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4eetFMNPhototropin-22.7.11.11.000
2z6dFMNPhototropin-22.7.11.10.605
4hiaFMNLOV protein/0.582
4hj6FMNLOV protein/0.580
1n9nFMNPutative blue light receptor/0.576
4eesFMNPhototropin-22.7.11.10.575
4eepFMNPhototropin-22.7.11.10.569
5efwFMNNPH1-1/0.565
2z6cFMNPhototropin-12.7.11.10.563
3t50FMNBlue-light-activated histidine kinase2.7.13.30.563
4eeuFMNPhototropin-22.7.11.10.563
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.562
5djtFMNNPH1-2/0.559
2pd8FADVivid PAS protein VVD/0.558
5djuFMNNPH1-2/0.553
2pr5FMNBlue-light photoreceptor/0.551
2pdtFADVivid PAS protein VVD/0.540
1n9lFMNPutative blue light receptor/0.539
2pd7FADVivid PAS protein VVD/0.538
4hhdFMNPhototropin-12.7.11.10.534
5dkkFMNPredicted protein/0.533
2v1aFMNNPH1-1/0.531
3is2FADVivid PAS protein VVD/0.529
3p7nFMNLight-activated DNA-binding protein EL222/0.527
3d72FADVivid PAS protein VVD/0.523
4eerFMNPhototropin-22.7.11.10.520
3sw1FMNSensory box protein/0.519
4kukRBFPutative blue-light photoreceptor/0.519
1g28FMNPHY3/0.514
4r38RBFBlue-light-activated histidine kinase 22.7.13.30.514
2v0uFMNNPH1-1/0.511
3hjkFADVivid PAS protein VVD/0.509
4kuoRBFPutative blue-light photoreceptor/0.509
4m10ICDProstaglandin G/H synthase 21.14.99.10.507
5j4eFMNSensory box protein/0.502
3ue6FMNAureochrome1/0.501
3c212BADNA integrity scanning protein DisA/0.497
1sxjADPReplication factor C subunit 5/0.494
4hj4FMNLOV protein/0.494
2c27ACOMycothiol acetyltransferase2.3.1.1890.493
3b9lAZZSerum albumin/0.493
5j3wFMNSensory box protein/0.492
1mjbACOHistone acetyltransferase ESA1/0.490
5jlaNADPutative short-chain dehydrogenase/reductase/0.490
2q61SF1Peroxisome proliferator-activated receptor gamma/0.489
3fhyATPPyridoxal kinase2.7.1.350.489
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.488
1xddAAYIntegrin alpha-L/0.487
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.486
1p0hACOMycothiol acetyltransferase2.3.1.1890.484
1me6IVSPlasmepsin-23.4.23.390.482
3keuATPPyridoxal kinase2.7.1.350.482
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.482
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.481
1mjaCOAHistone acetyltransferase ESA1/0.480
1nytNAPShikimate dehydrogenase (NADP(+))/0.480
2d8aNADL-threonine 3-dehydrogenase/0.480
3gfbNADL-threonine 3-dehydrogenase/0.480
3pcrGTPADP-ribosylation factor 6/0.480
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.479
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.479
2xvv9DNSerum albumin/0.479
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.479
4ienCOAPutative acyl-CoA hydrolase/0.479
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.478
1kqbFMNOxygen-insensitive NAD(P)H nitroreductase/0.478
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.478
4hj3FMNLOV protein/0.478
5hwsNAP2-dehydropantoate 2-reductase/0.478
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.477
2g37FADProline dehydrogenase/0.477
3pxvFMNNitroreductase/0.477
4z54GDPNeuronal-specific septin-3/0.477
3f3sNADLambda-crystallin homolog/0.476
3hyoADPPyridoxal kinase/0.476
4en4ATPPyridoxal kinase2.7.1.350.476
4hnbFMNLOV protein/0.476
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.475
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.475
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.475
5eccNAPDehydrofolate reductase type I/0.475
1xe55FEPlasmepsin-23.4.23.390.474
2gjlFMNNitronate monooxygenase1.13.12.160.474
2xvw9NRSerum albumin/0.474
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.474
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
3zdfNADGlyceraldehyde-3-phosphate dehydrogenase/0.474
4jldADPAdenylate kinase/0.474
2x7hPFNProstaglandin reductase 310.473
3ge6FMNNitroreductase/0.473
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.473
1dr2TAPDihydrofolate reductase1.5.1.30.472
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.472
2yxuATPPyridoxal kinase2.7.1.350.472
2yy7NADL-threonine dehydrogenase/0.472
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
4djaFAD(6-4) photolyase/0.471
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.471
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.470
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.470
4du82P0Mevalonate diphosphate decarboxylase/0.470
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.470
5cnoANPEpidermal growth factor receptor2.7.10.10.470
1dr3TAPDihydrofolate reductase1.5.1.30.469
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.468
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
1gc5ADPADP-dependent glucokinase2.7.1.1470.467
1q4gBFLProstaglandin G/H synthase 11.14.99.10.467
1x2hLPALipoate-protein ligase A6.3.1.200.467
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4a862ANMajor pollen allergen Bet v 1-A/0.466
4g6gFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.466
4ki8ADP60 kDa chaperonin/0.466
5cnnANPEpidermal growth factor receptor2.7.10.10.466
1hncGDNGlutathione S-transferase Mu 22.5.1.180.465
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.465
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.465
2wtkANPSTE20-related kinase adapter protein alpha/0.465
3ijoB4DGlutamate receptor 2/0.465
3wv9FEGHmd co-occurring protein HcgE/0.465
1fy7COAHistone acetyltransferase ESA1/0.464
2freFMNNAD(P)H-flavin oxidoreductase/0.464
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.464
3nbvANPKetohexokinase/0.464
4gxs0YSGlutamate receptor 2/0.464
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.464
3av7KYAUncharacterized protein/0.463
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.463
3lsiFADPyranose 2-oxidase/0.463
4dpuAGSMevalonate diphosphate decarboxylase/0.463
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.463
1e94ANPATP-dependent protease ATPase subunit HslU/0.462
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.462
1jedADPSulfate adenylyltransferase/0.462
2oapANPType II secretion system protein (GspE-2)/0.462
3gegNADShort-chain dehydrogenase/reductase SDR/0.462
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.462
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.462
3to6LYS_CMCHistone acetyltransferase ESA1/0.462
4dxd9PCCell division protein FtsZ/0.462
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.462
4l0qNADAlcohol dehydrogenase class-3/0.462
1tsvUMPThymidylate synthase/0.461
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.461
2q5g1FAPeroxisome proliferator-activated receptor delta/0.461
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.461
4ej0NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.461
4kl9NDPDihydrofolate reductase1.5.1.30.461
4y93746Tyrosine-protein kinase/0.461
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.460
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3w33W19Epidermal growth factor receptor2.7.10.10.460
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.460
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.460
1lbcCYZGlutamate receptor 2/0.459
1snyNAPLD36273p/0.459
1tqf32PBeta-secretase 13.4.23.460.459
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.459
1udaUFGUDP-glucose 4-epimerase5.1.3.20.459
2dteNAIGlucose 1-dehydrogenase related protein/0.459
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3uylTYDProbable NDP-rhamnosyltransferase/0.459
3w32W32Epidermal growth factor receptor2.7.10.10.459
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.459
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.459
5f54TMPSingle-stranded-DNA-specific exonuclease/0.459
1g1aNADdTDP-glucose 4,6-dehydratase/0.458
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.458
2npaMMBPeroxisome proliferator-activated receptor alpha/0.458
2ou2ACOHistone acetyltransferase KAT5/0.458
2q29ACOOxalyl-CoA decarboxylase4.1.1.80.458
2znq401Peroxisome proliferator-activated receptor delta/0.458
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.458
3ibqATPPyridoxal kinase/0.458
3kb1ADPIron-sulfur cluster carrier protein/0.458
3mx5UTPNucleoprotein/0.458
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3tjzGNPADP-ribosylation factor 1/0.458
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.458
4bb3KKAIsopenicillin N synthase1.21.3.10.458
4cf7ADPAdenylate kinase/0.458
4enhFVXCholesterol 24-hydroxylase/0.458
4h0yLARActin, alpha skeletal muscle/0.458
4mokFADPyranose 2-oxidase/0.458
1ae1NAPTropinone reductase 1/0.457
1i59ANPChemotaxis protein CheA2.7.13.30.457
2ad5ADPCTP synthase/0.457
2eglSAHDiphthine synthase/0.457
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.457
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.457
2zbaZBATrichothecene 3-O-acetyltransferase/0.457
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.457
3glmCOOGlutaconyl-CoA decarboxylase alpha subunit/0.457
3idbANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.457
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.457
4qecNAPElxO/0.457
1ai9NDPDihydrofolate reductase1.5.1.30.456
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1qy5NECEndoplasmin/0.456
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.456
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.456
2ql6ADPNicotinamide riboside kinase 1/0.456
2wa2SAMGenome polyprotein/0.456
3c1y2BADNA integrity scanning protein DisA/0.456
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.456
3sp9IL2Peroxisome proliferator-activated receptor delta/0.456
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.456
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.456
4hwkNAPSepiapterin reductase1.1.1.1530.456
4u03GTPCyclic GMP-AMP synthase/0.456
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.456
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.456
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.455
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2dwbANPAurora kinase A2.7.11.10.455
3af0GDPPantothenate kinase2.7.1.330.455
3l6jZ90Alr2278 protein/0.455
3oqkS52Renin3.4.23.150.455
4a5lNDPThioredoxin reductase/0.455
4coxIMNProstaglandin G/H synthase 21.14.99.10.455
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.455
4fd2ADPChaperone protein ClpB/0.455
4fdpFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.455
4oaqNDPR-specific carbonyl reductase/0.455
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.454
1lf3EH5Plasmepsin-23.4.23.390.454
2b7aIZATyrosine-protein kinase JAK2/0.454
2p2qPRXAcetyl-coenzyme A synthetase/0.454
2pb4SAHDiphthine synthase/0.454
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.454
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.454
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.454
3d8bADPFidgetin-like protein 13.6.40.454
3m6iNADL-arabinitol 4-dehydrogenase1.1.1.120.454
3qrwNDPPutative ketoacyl reductase1.3.10.454
4hjoAQ4Epidermal growth factor receptor2.7.10.10.454
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.454
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.454
1e3eNAIAlcohol dehydrogenase 41.1.1.10.453
1f0xFADD-lactate dehydrogenase1.1.1.280.453
1h6dNDPGlucose--fructose oxidoreductase1.1.99.280.453
1um0FMNChorismate synthase/0.453
2i7pACOPantothenate kinase 32.7.1.330.453
2znpK55Peroxisome proliferator-activated receptor delta/0.453
3v9v21LPeroxisome proliferator-activated receptor gamma/0.453
4lcjNADC-terminal-binding protein 2/0.453
4rpgFADUDP-galactopyranose mutase5.4.99.90.453
4xyeNADFormate dehydrogenase/0.453
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.453
1eioGCHGastrotropin/0.452
1p9wANPType II secretion system protein E/0.452
2bz5AB4Heat shock protein HSP 90-alpha/0.452
2cbrA80Cellular retinoic acid-binding protein 1/0.452
2po7CHDFerrochelatase, mitochondrial4.99.1.10.452
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.452
2yutNAPPutative short-chain oxidoreductase/0.452
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.452
2zrfDTPProtein RecA/0.452
3junAJDPhenazine biosynthesis protein A/B/0.452
3jynNDPQuinone oxidoreductase/0.452
3jzdNADMaleylacetate reductase/0.452
3lqfNADGalactitol dehydrogenase/0.452
3ntgD72Prostaglandin G/H synthase 21.14.99.10.452
3s55NADPutative short-chain dehydrogenase/reductase/0.452
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.452
4esoNAPPutative oxidoreductase/0.452
4q73FADBifunctional protein PutA/0.452
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
1bcpATPPertussis toxin subunit 4/0.451
1bcpATPPertussis toxin subunit 5/0.451
1bk0ACVIsopenicillin N synthase1.21.3.10.451
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.451
1llzFMNFerredoxin-dependent glutamate synthase 21.4.7.10.451
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2hckQUETyrosine-protein kinase HCK2.7.10.20.451
2huxSAHDiphthine synthase/0.451
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.451
3aezGDPPantothenate kinase2.7.1.330.451
3oqfS51Renin3.4.23.150.451
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3sf6FDAGlutaryl-CoA dehydrogenase/0.451
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.451
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.451
5e92ANPTGF-beta receptor type-22.7.11.300.451
1c1dNAIPhenylalanine dehydrogenase/0.450
1d7lRFLp-hydroxybenzoate hydroxylase/0.450
1h74ADPHomoserine kinase2.7.1.390.450
1i2cUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.450
1y4lSVRBasic phospholipase A2 homolog 2/0.450
1zemNADXylitol dehydrogenase/0.450
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2ejzSAHDiphthine synthase/0.450
3mx2TTPNucleoprotein/0.450
4hge15VTyrosine-protein kinase JAK2/0.450
4ji91M3Tyrosine-protein kinase JAK2/0.450
4lj9ACPChaperone protein ClpB/0.450
4rphFADUDP-galactopyranose mutase5.4.99.90.450
1fm4DXCMajor pollen allergen Bet v 1-L/0.449
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.449
1ia1NDPDihydrofolate reductase1.5.1.30.449
1nzfUPGDNA beta-glucosyltransferase/0.449
1xvaSAMGlycine N-methyltransferase2.1.1.200.449
2b56UTPRNA editing complex protein MP57/0.449
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.449
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.449
2pwcG3GGag-Pol polyprotein3.4.23.160.449
2z4sADPChromosomal replication initiator protein DnaA/0.449
2zkjADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.449
3d84NDPDihydrofolate reductase1.5.1.30.449
3k2bNADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.449
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.449
3l77NJPShort-chain alcohol dehydrogenase/0.449
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.449
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.449
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.449
4g7gVFVLanosterol 14-alpha-demethylase/0.449
4nmdFDABifunctional protein PutA/0.449
4xj3GTPCyclic GMP-AMP synthase/0.449
4yswFADXanthine dehydrogenase/oxidase/0.449
4zseANPEpidermal growth factor receptor2.7.10.10.449
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.449
5idwNAPShort-chain dehydrogenase/reductase SDR/0.449
1lcbTMPThymidylate synthase/0.448
1pdhFASp-hydroxybenzoate hydroxylase/0.448
1rfuADPPyridoxal kinase2.7.1.350.448
1tj0FADBifunctional protein PutA1.5.5.20.448
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.448
2zsaADPPantothenate kinase2.7.1.330.448
2zsbADPPantothenate kinase2.7.1.330.448
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.448
3ad9NADSubunit alpha of sarocosine oxidase/0.448
3bbrBHYGlutamate receptor 2/0.448
3eljGS7Mitogen-activated protein kinase 82.7.11.240.448
3enkUPGUDP-glucose 4-epimerase/0.448
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.448
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.448
4gavFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.448
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.448
4prxADPDNA gyrase subunit B/0.448
4qedNAPElxO/0.448
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.448
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.448
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.447
1n3rGTPGTP cyclohydrolase 13.5.4.160.447
2y0mACOHistone acetyltransferase KAT8/0.447
2yj4ATPCopper-transporting ATPase/0.447
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.447
3nglNAPBifunctional protein FolD/0.447
3qlrNDPDihydrofolate reductase1.5.1.30.447
4m6jNDPDihydrofolate reductase1.5.1.30.447
4rrxLURProstaglandin G/H synthase 21.14.99.10.447
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.447
4zohFADPutative oxidoreductase FAD-binding subunit/0.447
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.447
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.446
2dknNAI3-alpha-hydroxysteroid dehydrogenase/0.446
2dv4SAHDiphthine synthase/0.446
2gjnFMNNitronate monooxygenase1.13.12.160.446
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.446
2rhgIGPTryptophan synthase alpha chain/0.446
2x7bCOAN-alpha-acetyltransferase2.3.10.446
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.446
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.446
5hsaFASAlcohol oxidase 11.1.3.130.446
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.445
1icvFMNOxygen-insensitive NAD(P)H nitroreductase/0.445
1n5dNDPCarbonyl reductase [NADPH] 1/0.445
1nptNADGlyceraldehyde-3-phosphate dehydrogenase/0.445
1sb9UPGWbpP/0.445
2abbFMNPentaerythritol tetranitrate reductase/0.445
2cmvNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.445
2ea2F77Methionine aminopeptidase 2/0.445
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.445
2ft9CHDFatty acid-binding protein 2, liver/0.445
2nuaCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.445
2o12FMNChorismate synthase/0.445
2pwrG4GGag-Pol polyprotein3.4.23.160.445
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.445
2x3nFADProbable FAD-dependent monooxygenase/0.445
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.445
3cgbCOACoenzyme A disulfide reductase/0.445
3m31FADEndoplasmic oxidoreductin-11.8.40.445
3mvm39PMitogen-activated protein kinase 14/0.445
3pe2E1BCasein kinase II subunit alpha2.7.11.10.445
3sdkP3NProteasome subunit beta type-53.4.25.10.445
3sdkP3NProteasome subunit beta type-63.4.25.10.445
3tdj3TJGlutamate receptor 2/0.445
3x22FMNOxygen-insensitive NAD(P)H nitroreductase/0.445
4a84DXCMajor pollen allergen Bet v 1-A/0.445
1bw9NADPhenylalanine dehydrogenase/0.444
1bwsNDPGDP-L-fucose synthase/0.444
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1eupASD6-deoxyerythronolide B hydroxylase/0.444
1f8fNADBenzyl alcohol dehydrogenase/0.444
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
1ht2ADPATP-dependent protease ATPase subunit HslU/0.444
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.444
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.444
2pmnK51Protein kinase 7/0.444
2vwhNAPGlucose 1-dehydrogenase/0.444
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.444
2yj5ATPCopper-transporting ATPase/0.444
3cukFADD-amino-acid oxidase1.4.3.30.444
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3nu3478Gag-Pol polyprotein3.4.23.160.444
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.444
3uf6CODLmo1369 protein/0.444
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.444
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4ehzJAKTyrosine-protein kinase JAK1/0.444
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.444
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
4hdhATPGenome polyprotein2.7.7.480.444
4i6gFADCryptochrome-2/0.444
4l4xNDPAmphI/0.444
4nxxGDPMitochondrial dynamics protein MID51/0.444
4pzrCOAHistone acetyltransferase p300/0.444
4umxNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
4wudANPDNA gyrase subunit B/0.444
1f0yCAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1juvNDPDihydrofolate reductase1.5.1.30.443
2dsgSAHDiphthine synthase/0.443
2mwgFMNBlue-light photoreceptor/0.443
2qenADPWalker-Type ATPase/0.443
2x0iNAIMalate dehydrogenase/0.443
2yvgNADFerredoxin reductase/0.443
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3d8vUD1Bifunctional protein GlmU/0.443
3h4lANPDNA mismatch repair protein PMS1/0.443
3qt62P0Mevalonate diphosphate decarboxylase/0.443
3sl2ATPSensor histidine kinase WalK/0.443
3tdvGDPGentamicin resistance protein/0.443
3v2uATPProtein GAL3/0.443
4az3S35Lysosomal protective protein3.4.16.50.443
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.443
4d5gFADCyclohexane-1,2-dione hydrolase3.7.1.110.443
4dieC5PCytidylate kinase/0.443
4emiNADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component1.18.1.30.443
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.443
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4ikeADPAdenylate kinase/0.443
4m83ERYOleandomycin glycosyltransferase2.4.10.443
4rf2NAPNADPH dependent R-specific alcohol dehydrogenase/0.443
1bil0IURenin3.4.23.150.442
1ie3NADMalate dehydrogenase/0.442
1ipeNDPTropinone reductase 21.1.1.2360.442
1x1cSAHC-20 methyltransferase/0.442
2ed5SAHDiphthine synthase/0.442
2fsvNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.442
2vbdV10Isopenicillin N synthase1.21.3.10.442
2vu3LZECyclin-dependent kinase 22.7.11.220.442
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.442
2y3rTIRTamL/0.442
3eyhIZATyrosine-protein kinase JAK1/0.442
3fx6BPXCarboxypeptidase A13.4.17.10.442
3h06VBPGlutamate receptor 2/0.442
3hx4ANPCalmodulin-domain protein kinase 1/0.442
3oibFDAPutative acyl-CoA dehydrogenase/0.442
3qaaG04Gag-Pol polyprotein3.4.23.160.442
3qtwX3ACyclin-dependent kinase 22.7.11.220.442
3wagTYDGlycosyltransferase/0.442
4a4zANPAntiviral helicase SKI23.6.4.130.442
4a83DXCMajor pollen allergen Bet v 1-A/0.442
4burNADApoptosis-inducing factor 1, mitochondrial1.1.10.442
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.442
4oztP1AEcdysone receptor, putative/0.442
4q72FADBifunctional protein PutA/0.442
5lc1NADL-threonine 3-dehydrogenase/0.442
1b16NAQAlcohol dehydrogenase1.1.1.10.441
1kqdFMNOxygen-insensitive NAD(P)H nitroreductase/0.441
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.441
1v9aSAHUncharacterized protein/0.441
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.441
1zgdNAPChalcone reductase/0.441
2owuSAHDiphthine synthase/0.441
2rc3NADCBS domain/0.441
2y9qANPMitogen-activated protein kinase 12.7.11.240.441
3af1GDPPantothenate kinase2.7.1.330.441
3clyACPFibroblast growth factor receptor 2/0.441
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3hk1B64Fatty acid-binding protein, adipocyte/0.441
3mb714ICasein kinase II subunit alpha2.7.11.10.441
3qdlFMNOxygen-insensitive NADPH nitroreductase/0.441
3qttANPPantothenate synthetase/0.441
3slkNDPPolyketide synthase extender module 2/0.441
3x21FMNOxygen-insensitive NAD(P)H nitroreductase/0.441
4ambDUDPutative glycosyl transferase/0.441
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4bfxZVXPantothenate kinase2.7.1.330.441
4d9eLCSD-cysteine desulfhydrase/0.441
4dymIYZActivin receptor type-12.7.11.300.441
4e03ADPPlasmid partitioning protein ParF/0.441
4h3qANPMitogen-activated protein kinase 12.7.11.240.441
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.441
4jl5ADPAdenylate kinase/0.441
4n9iPCGCatabolite expression activator/0.441
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.441
4rosAPRMalate dehydrogenase/0.441
5i4nATPTyrosine-protein kinase JAK2/0.441
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.441
1necFMNOxygen-insensitive NAD(P)H nitroreductase10.440
1nffNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.440
1powFADPyruvate oxidase1.2.3.30.440
1tj2FADBifunctional protein PutA1.5.5.20.440
1uxjNADMalate dehydrogenase/0.440
1zrzBI1Protein kinase C iota type2.7.11.130.440
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.440
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.440
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2p5cSAHDiphthine synthase/0.440
2qrdADP5'-AMP-activated protein kinase subunit gamma/0.440
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
2xx91NFGlutamate receptor 2/0.440
3a4vNADNDP-sugar epimerase/0.440
3b70NAPEnoyl reductase LovC10.440
3h86AP5Adenylate kinase/0.440
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.440
3nieANPMitogen-activated protein kinase/0.440
3p2oNADBifunctional protein FolD/0.440
4dptAGSMevalonate diphosphate decarboxylase/0.440
4ejmNAPPutative zinc-binding dehydrogenase/0.440
4g3jVNTLanosterol 14-alpha-demethylase/0.440
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.440
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.440
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.440
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.440