sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 1.000 | |
| 4b0i | KBP | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.682 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.510 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.500 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.500 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.492 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.491 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.486 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.486 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.485 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.484 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.484 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 3abx | RCB | Glucanase | / | 0.480 | |
| 3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.480 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.479 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.479 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.479 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.479 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.478 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.478 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.478 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.477 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.477 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.477 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.475 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.474 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.474 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 2r8p | T6F | Transketolase 1 | / | 0.473 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.473 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.473 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.472 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.472 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.472 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.471 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.470 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.470 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 5a3b | APR | SIR2 family protein | / | 0.470 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.470 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.469 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.469 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.468 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.468 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.468 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.468 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.467 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.466 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.466 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.466 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.466 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.466 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.465 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.465 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.465 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.465 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.464 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.464 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.464 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.463 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.463 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.463 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.463 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.463 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.463 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.463 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.462 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.462 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.462 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.461 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.461 | |
| 1xgj | HTC | Beta-lactamase | 3.5.2.6 | 0.461 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.461 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.461 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.461 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.460 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.460 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.460 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.459 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3f6s | FMN | Flavodoxin | / | 0.459 | |
| 3lt2 | FT3 | Enoyl-ACP reductase | / | 0.459 | |
| 3mje | NDP | AmphB | / | 0.459 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.459 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.458 | |
| 1zdw | FLV | Prenyltransferase | / | 0.458 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.458 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.458 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.458 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.458 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.458 | |
| 4boe | CLR | Japanin | / | 0.458 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.458 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.458 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.457 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.457 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.457 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.457 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.456 | |
| 1njj | ORX | Ornithine decarboxylase | / | 0.456 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.456 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.456 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.456 | |
| 3r6c | 17N | Anthranilate phosphoribosyltransferase | / | 0.456 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.456 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.456 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.455 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.455 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.455 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.455 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.455 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.455 | |
| 3am5 | TCL | Enoyl-ACP reductase | / | 0.455 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.455 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.455 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.455 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.455 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.454 | |
| 1iy8 | NAD | Levodione reductase | / | 0.454 | |
| 1n06 | ADP | Riboflavin kinase | 2.7.1.26 | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 2r8o | T5X | Transketolase 1 | / | 0.454 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.454 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.454 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.454 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.454 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.453 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.453 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.453 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.453 | |
| 1zxl | JP1 | Enoyl-ACP reductase | / | 0.453 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.453 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3gb4 | D3M | DdmC | / | 0.453 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.453 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.452 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.452 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.452 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.452 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.452 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.452 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.452 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.452 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.452 | |
| 4phl | PIL | Phosphodiesterase | / | 0.452 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.452 | |
| 1c7o | PPG | Hemolysin | / | 0.451 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.451 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.451 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.451 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.451 | |
| 4tld | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.451 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.451 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.450 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 1you | PFD | Collagenase 3 | 3.4.24 | 0.450 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.450 | |
| 2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.450 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.450 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.450 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.450 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.450 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.450 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.449 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 1nhg | TCL | Enoyl-ACP reductase | / | 0.449 | |
| 1ppj | ANY | Cytochrome b | / | 0.449 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 2j08 | IRF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.449 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.449 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.449 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.449 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.449 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.449 | |
| 5dp2 | NAP | CurF | / | 0.449 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.448 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.448 | |
| 1zw1 | TN5 | Enoyl-ACP reductase | / | 0.448 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.448 | |
| 2ejk | SAH | Diphthine synthase | / | 0.448 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.448 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.448 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.448 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.448 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.448 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.448 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.448 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.448 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.448 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.448 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.447 | |
| 1e2n | RCA | Thymidine kinase | / | 0.447 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.447 | |
| 1jf0 | CZH | Obelin | / | 0.447 | |
| 1s7n | COA | Acetyl transferase | / | 0.447 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.447 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.447 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.447 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.447 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.447 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.447 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.447 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.447 | |
| 3sig | AR6 | Uncharacterized protein | / | 0.447 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.447 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.447 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.447 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.446 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 2emu | SAH | Diphthine synthase | / | 0.446 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.446 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.446 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3coz | 54H | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.446 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.446 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.445 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.445 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.445 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.445 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.445 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3bhr | THG | Thymidylate synthase | / | 0.445 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.445 | |
| 4dl9 | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.445 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.445 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.445 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.445 | |
| 1knp | FAD | L-aspartate oxidase | 1.4.3.16 | 0.444 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.444 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.444 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.444 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.444 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.444 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.444 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.444 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.444 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.444 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.444 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.444 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.444 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.443 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.443 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.443 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.443 | |
| 2dsg | SAH | Diphthine synthase | / | 0.443 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 2owk | SAH | Diphthine synthase | / | 0.443 | |
| 2pca | SAH | Diphthine synthase | / | 0.443 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.443 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.443 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.443 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.443 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.443 | |
| 4f6r | GDP | Tubulin beta chain | / | 0.443 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.443 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.442 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.442 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.442 | |
| 2o2y | TCL | Enoyl-ACP reductase | / | 0.442 | |
| 2vhw | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.442 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.442 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
| 4e32 | DWN | Methyltransferase | / | 0.442 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.442 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.442 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.441 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.441 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.441 | |
| 2b4y | APR | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.441 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.441 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.441 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.441 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.441 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.441 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 4hdg | GTP | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.441 | |
| 5doz | NDP | JamJ | / | 0.441 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1ysl | COA | Hydroxymethylglutaryl-CoA synthase | 2.3.3.10 | 0.440 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.440 | |
| 2bel | CBO | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.440 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.440 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.440 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.440 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3kxo | KXO | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.440 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4jkt | 04A | Glutaminase kidney isoform, mitochondrial | 3.5.1.2 | 0.440 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.440 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.440 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.440 |