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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3chr4BSLeukotriene A-4 hydrolase3.3.2.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3chr4BSLeukotriene A-4 hydrolase3.3.2.61.000
3ful52DLeukotriene A-4 hydrolase3.3.2.60.612
3fui812Leukotriene A-4 hydrolase3.3.2.60.604
3fuj00GLeukotriene A-4 hydrolase3.3.2.60.581
4rsyB3NLeukotriene A-4 hydrolase3.3.2.60.570
3chs4BULeukotriene A-4 hydrolase3.3.2.60.569
1ygjRMCPyridoxal kinase2.7.1.350.524
3ftxRE2Leukotriene A-4 hydrolase3.3.2.60.524
3cho4BGLeukotriene A-4 hydrolase3.3.2.60.522
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.510
1exa394Retinoic acid receptor gamma/0.505
2ydoADNAdenosine receptor A2a/0.503
5d1bTSNHistone deacetylase 83.5.1.980.499
4lb2DM5Serum albumin/0.497
3qm4PN0Cytochrome P450 2D6/0.493
1dgfNDPCatalase1.11.1.60.488
1dlrMXADihydrofolate reductase1.5.1.30.488
4ug2NGIAdenosine receptor A2a/0.488
2gpvOHTEstrogen-related receptor gamma/0.486
2pnuENMAndrogen receptor/0.485
1s3uTQDDihydrofolate reductase1.5.1.30.483
2r6hFADNa(+)-translocating NADH-quinone reductase subunit F/0.481
4ea2RWZDehydrosqualene synthase/0.481
5bt42LOBromodomain-containing protein 4/0.481
3e5aVX6Aurora kinase A2.7.11.10.479
3ou6SAMSAM-dependent methyltransferase/0.478
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.477
4g1nNZTPyruvate kinase PKM2.7.1.400.477
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.476
4awq592Heat shock protein HSP 90-alpha/0.475
4kbn25UDihydrofolate reductase1.5.1.30.475
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.475
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.474
3hv3R49Mitogen-activated protein kinase 14/0.474
3p6nDSOCamphor 5-monooxygenase1.14.15.10.474
3sr4TT8Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.474
1fcx184Retinoic acid receptor gamma/0.473
3vf60H6Glucokinase2.7.1.20.473
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.473
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.473
1s9dAFBCytohesin-2/0.472
1s9dAFBADP-ribosylation factor 1/0.472
1w83L11Mitogen-activated protein kinase 14/0.472
2clhF19Tryptophan synthase alpha chain/0.472
2dhfDZFDihydrofolate reductase1.5.1.30.472
3hqdANPKinesin-like protein KIF11/0.471
3n0hTOPDihydrofolate reductase1.5.1.30.471
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.471
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.471
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.471
3zrrPXGSerine-pyruvate aminotransferase (AgxT)/0.470
5bsrCOA4-coumarate--CoA ligase 26.2.1.120.470
5kf2ACOPredicted acetyltransferase/0.470
3nyaJTZBeta-2 adrenergic receptor/0.470
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.469
2ydvNECAdenosine receptor A2a/0.469
3ozsOZSCatechol O-methyltransferase2.1.1.60.469
3pg3DG7Mitogen-activated protein kinase 14/0.469
1fd0254Retinoic acid receptor gamma/0.468
1oc1ASVIsopenicillin N synthase1.21.3.10.468
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2jc6QPPCalcium/calmodulin-dependent protein kinase type 1D2.7.11.170.468
2onyTMJPhenylethanolamine N-methyltransferase2.1.1.280.468
2vqqTFGHistone deacetylase 43.5.1.980.468
2vxkCOAGlucosamine 6-phosphate acetyltransferase, putative/0.468
3qp8HL0Transcriptional activator, LuxR/UhpA family of regulators/0.468
4kfj1R0Dihydrofolate reductase1.5.1.30.468
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.467
3lakKR1Gag-Pol polyprotein2.7.7.490.467
3p6oETGCamphor 5-monooxygenase1.14.15.10.467
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.467
4b4vL34Bifunctional protein FolD/0.467
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.467
4e2yJHZMethyltransferase/0.467
4kd79DRDihydrofolate reductase1.5.1.30.467
5g53NECAdenosine receptor A2a/0.467
1blzACVIsopenicillin N synthase1.21.3.10.466
1q1gMTIPurine nucleoside phosphorylase/0.466
2jdcCAOProbable acetyltransferase/0.466
2ycwCAUBeta-1 adrenergic receptor/0.466
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.466
3dp9BIG5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.466
4ixeIXEDihydrofolate reductase1.5.1.30.466
1kyzFERCaffeic acid 3-O-methyltransferase2.1.1.680.465
3up0D7SaceDAF-12/0.465
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.465
1qiqACCIsopenicillin N synthase1.21.3.10.464
1uwhBAXSerine/threonine-protein kinase B-raf2.7.11.10.464
2xkc4VQSerine/threonine-protein kinase Nek22.7.11.10.464
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.464
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.464
4rh10TTSpore photoproduct lyase/0.464
1synF89Thymidylate synthase/0.463
1u0wSTLChalcone synthase 22.3.1.740.463
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.463
3acy702Dehydrosqualene synthase/0.463
3f3y4OABile salt sulfotransferase2.8.2.140.463
3n87N873-dehydroquinate dehydratase4.2.1.100.463
4af3VX6Aurora kinase B2.7.11.10.463
4dm8REARetinoic acid receptor beta/0.463
3qakUKAAdenosine receptor A2a/0.463
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.462
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
1sqpMYXCytochrome b/0.461
3nj8NJ8Enoyl-acyl carrier reductase/0.461
3ou7SAMSAM-dependent methyltransferase/0.461
4dvi2IWTankyrase-12.4.2.300.461
5k2bZMAAdenosine receptor A2a/0.461
2xk730ESerine/threonine-protein kinase Nek22.7.11.10.460
3aosJH2Hemolymph juvenile hormone binding protein/0.460
3p9tTCLRepressor/0.460
3s41S41Glucokinase2.7.1.20.460
4eh7IRGMitogen-activated protein kinase 14/0.460
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4m6p20RNicotinamide phosphoribosyltransferase2.4.2.120.460
1dtpAPUDiphtheria toxin/0.459
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.459
2ejzSAHDiphthine synthase/0.459
2vqoTFGHistone deacetylase 43.5.1.980.459
3ghvGHCDihydrofolate reductase1.5.1.30.459
1ohkCOPDihydrofolate reductase1.5.1.30.458
1sqbAZOCytochrome b/0.458
2g8yNADHydroxycarboxylate dehydrogenase B/0.458
2onzTMJPhenylethanolamine N-methyltransferase2.1.1.280.458
3n1t5GPPurine nucleoside phosphoramidase/0.458
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.458
3p0fBAUUridine phosphorylase 22.4.2.30.458
4amjCVDBeta-1 adrenergic receptor/0.458
4tkg09LTankyrase-22.4.2.300.458
1kf6HQOFumarate reductase iron-sulfur subunit1.3.5.10.457
1kf6HQOFumarate reductase subunit C/0.457
1kf6HQOFumarate reductase subunit D/0.457
2pupADPMethylthioribose kinase2.7.1.1000.457
3d4bDZDNAD-dependent protein deacetylase/0.457
3dlgGWEGag-Pol polyprotein2.7.7.490.457
3eon341Glutaryl-CoA dehydrogenase/0.457
3gkjHC3Niemann-Pick C1 protein/0.457
3tdkUPGUDP-glucose 6-dehydrogenase1.1.1.220.457
4b4w9L9Bifunctional protein FolD/0.457
4e0u0MVCyclic dipeptide N-prenyltransferase/0.457
4hlf15ZTankyrase-22.4.2.300.457
4phlPILPhosphodiesterase/0.457
4xugF9FTryptophan synthase alpha chain/0.457
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.456
1m9hNAD2,5-diketo-D-gluconic acid reductase A1.1.1.3460.456
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
1xdkREARetinoic acid receptor beta/0.456
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.456
3hkyIX6Genome polyprotein2.7.7.480.456
3i6rJ5ZDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.456
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
3l3rOAGDihydrofolate reductase1.5.1.30.456
3p6pA6BCamphor 5-monooxygenase1.14.15.10.456
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.456
4dm6TTBRetinoic acid receptor beta/0.456
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.456
4n3r2GUTankyrase-12.4.2.300.456
5ahkFADAcetolactate synthase II, large subunit/0.456
5bn4ANPV-type ATP synthase alpha chain/0.456
5irnADPNucleotide binding oligomerization domain containing 2/0.456
3uzcT4EAdenosine receptor A2a/0.456
1icqOPD12-oxophytodienoate reductase 11.3.1.420.455
2cleF6FTryptophan synthase alpha chain/0.455
2mjiKTRFatty acid-binding protein, intestinal/0.455
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.455
3p6mDSOCamphor 5-monooxygenase1.14.15.10.455
3t8xT8XT-cell surface glycoprotein CD1b/0.455
3zkuHCVIsopenicillin N synthase1.21.3.10.455
4biwANPSensor histidine kinase CpxA/0.455
4bvhOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.455
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.455
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.455
5uviZMAAdenosine receptor A2a/0.455
3d4sTIMBeta-2 adrenergic receptor/0.455
1jjtBDSBeta-lactamase/0.454
1o6qR17Squalene--hopene cyclase4.2.1.1290.454
1olmVTQSEC14-like protein 2/0.454
1pd9CO4Dihydrofolate reductase1.5.1.30.454
1pkfEPDEpothilone C/D epoxidase1.140.454
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.454
2vbdV10Isopenicillin N synthase1.21.3.10.454
3h3t16HCollagen type IV alpha-3-binding protein/0.454
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.454
3sl2ATPSensor histidine kinase WalK/0.454
3vhmNPKAvidin/0.454
4a87NARMajor pollen allergen Bet v 1-A/0.454
4afeGGYSerine/threonine-protein kinase Nek22.7.11.10.454
4bfxZVXPantothenate kinase2.7.1.330.454
4but31FTankyrase-22.4.2.300.454
4buuF38Tankyrase-22.4.2.300.454
4dch4DCGlucokinase2.7.1.20.454
4hknLU2Tankyrase-22.4.2.300.454
4hlh20DTankyrase-22.4.2.300.454
4hlk431Tankyrase-22.4.2.300.454
1fcy564Retinoic acid receptor gamma/0.453
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.453
2obfF83Phenylethanolamine N-methyltransferase2.1.1.280.453
2pjl047Steroid hormone receptor ERR1/0.453
3irxUDRGag-Pol polyprotein2.7.7.490.453
3nwlNDPCatalase1.11.1.60.453
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.453
4isf1FXGlucokinase2.7.1.20.453
5bn3ADPV-type ATP synthase alpha chain/0.453
5bn3ADPNEQ263/0.453
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.453
5k2cZMAAdenosine receptor A2a/0.453
1diaL24C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.452
1qtqQSIGlutamine--tRNA ligase6.1.1.180.452
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
2ban357Gag-Pol polyprotein2.7.7.490.452
3fowIMHPurine nucleoside phosphorylase/0.452
3ou2SAHSAM-dependent methyltransferase/0.452
3qlzQLZUncharacterized protein/0.452
3vg9ZMAAdenosine receptor A2a/0.452
4jvlESTEstrogen sulfotransferase2.8.2.40.452
4mmd29ENa(+):neurotransmitter symporter (Snf family)/0.452
4xbjIN5Alanine racemase, biosynthetic/0.452
1cd2FOLDihydrofolate reductase1.5.1.30.451
1crbRTLRetinol-binding protein 1/0.451
1pz1NAPGeneral stress protein 69/0.451
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
1ygkRRCPyridoxal kinase2.7.1.350.451
2e95B75Geranylgeranyl pyrophosphate synthase/0.451
2fxuBIDActin, alpha skeletal muscle/0.451
2g8nF83Phenylethanolamine N-methyltransferase2.1.1.280.451
2gs9SAHUncharacterized protein/0.451
2j5sKTAAlr4455 protein/0.451
2rqfJH3Hemolymph juvenile hormone binding protein/0.451
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
3p2oNADBifunctional protein FolD/0.451
4dvq1CACytochrome P450 11B2, mitochondrial1.14.15.40.451
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
1b87ACOAac(6')-Ii protein/0.450
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1tfz8694-hydroxyphenylpyruvate dioxygenase1.13.11.270.450
1xp6AIUEstrogen receptor/0.450
1zosMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.450
2cbrA80Cellular retinoic acid-binding protein 1/0.450
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.450
3abiNADUncharacterized protein/0.450
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.450
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
4bueJQFTankyrase-22.4.2.300.450
4ead0NPThymidine phosphorylase2.4.2.40.450
4ixc1JDGlucokinase2.7.1.20.450
4klaCHDFerrochelatase, mitochondrial4.99.1.10.450
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.450
1fmlRTLRetinol dehydratase/0.449
1kmsLIHDihydrofolate reductase1.5.1.30.449
1nw4IMHPurine nucleoside phosphorylase/0.449
1rsgFADPolyamine oxidase FMS1/0.449
1zz1SHHHistone deacetylase-like amidohydrolase3.5.10.449
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.449
2bf7HBIPteridine reductase 11.5.1.330.449
2fzjDH3Dihydrofolate reductase1.5.1.30.449
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.449
2wpwACOOrf14/0.449
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.449
3b7dCNIGlutamate receptor 2/0.449
3b82NADExotoxin A2.4.2.360.449
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3h3r14HCollagen type IV alpha-3-binding protein/0.449
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.449
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.449
3tdaPN0Cytochrome P450 2D6/0.449
4bus32FTankyrase-22.4.2.300.449
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.449
4jlm1NNDeoxycytidine kinase2.7.1.740.449
4mt92D6Tankyrase-12.4.2.300.449
4qknJMSAlpha-ketoglutarate-dependent dioxygenase FTO/0.449
5iua6DXAdenosine receptor A2a/0.449
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.448
1ly3COGDihydrofolate reductase1.5.1.30.448
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.448
1sqqOSTCytochrome b/0.448
1wl4COAAcetyl-CoA acetyltransferase, cytosolic2.3.1.90.448
2nnlERDDihydroflavonol 4-reductase1.1.1.2190.448
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.448
2xlpNAPPutative flavin-containing monooxygenase/0.448
2zscBTNTamavidin2/0.448
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.448
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.448
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3mnrSD1Heat shock protein HSP 90-alpha/0.448
3nwe662Catechol O-methyltransferase2.1.1.60.448
3rl45GPMetallophosphoesterase MPPED23.10.448
4g48PZBMycocyclosin synthase1.14.21.90.448
4j6cSTRCytochrome P450 monooxygenase/0.448
4jpg1OXPyruvate kinase PKM2.7.1.400.448
4qa1B3NHistone deacetylase 83.5.1.980.448
5ab7MLCNonspecific lipid-transfer protein, putative/0.448
3emlZMAAdenosine receptor A2a/0.448
3uzaT4GAdenosine receptor A2a/0.448
1dibL34C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.447
1drfFOLDihydrofolate reductase1.5.1.30.447
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.447
1n71COAAac(6')-Ii protein/0.447
1pd8CO4Dihydrofolate reductase1.5.1.30.447
1yhjR6CPyridoxal kinase2.7.1.350.447
2obxINI6,7-dimethyl-8-ribityllumazine synthase 22.5.1.780.447
3a1l2CCCytochrome P450/0.447
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
3ipq965Oxysterols receptor LXR-alpha/0.447
3l70JZVCytochrome b/0.447
3tfn2CJDehydrosqualene synthase/0.447
4ddrMMVDihydrofolate reductase1.5.1.30.447
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.447
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.447
4jwr1MYE3 ubiquitin-protein ligase Mdm26.3.20.447
4li61XOTankyrase-12.4.2.300.447
5a4wQCTGlutathione S-transferase F22.5.1.180.447
5jtbZMAAdenosine receptor A2a/0.447
1bk0ACVIsopenicillin N synthase1.21.3.10.446
1el4CTZObelin/0.446
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.446
1pq944BOxysterols receptor LXR-beta/0.446
1pr5TBNPurine nucleoside phosphorylase DeoD-type/0.446
1uhlMEIRetinoic acid receptor RXR-beta/0.446
1uyhPU0Heat shock protein HSP 90-alpha/0.446
1wxyFRKAdenosine deaminase3.5.4.40.446
1yf3SAHDNA adenine methylase/0.446
1zdwFLVPrenyltransferase/0.446
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.446
2q3eUPGUDP-glucose 6-dehydrogenase1.1.1.220.446
2wksCB63-dehydroquinate dehydratase4.2.1.100.446
3dmjGWEPol protein/0.446
3fhxPXLPyridoxal kinase2.7.1.350.446
3fnhJPJEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.446
3wbwNDPPutative 2,5-diketo-D-gluconic acid reductase/0.446
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.446
4ixfIXFDihydrofolate reductase1.5.1.30.446
4kak06UDihydrofolate reductase1.5.1.30.446
4y1bNAPAntE/0.446
5aku29FTankyrase-22.4.2.300.446
1dggNDPCatalase1.11.1.60.445
1dghNDPCatalase1.11.1.60.445
1g49111Stromelysin-13.4.24.170.445
1lkeDOGBilin-binding protein/0.445
2v57PRLTetR family transcriptional regulator/0.445
2xlsFADPutative flavin-containing monooxygenase/0.445
3ba6AN2Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.445
3eufBAUUridine phosphorylase 1/0.445
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3igvB80Genome polyprotein2.7.7.480.445
3p0eBAUUridine phosphorylase 22.4.2.30.445
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.445
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.445
4bvnP32Beta-1 adrenergic receptor/0.445
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.445
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4dhyS41Glucokinase2.7.1.20.445
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.445
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.445
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4n4v2GYTankyrase-12.4.2.300.445
4xoiGTPTransforming protein RhoA/0.445
1e7wMTXPteridine reductase 11.5.1.330.444
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1fm69CRRetinoic acid receptor RXR-alpha/0.444
1hb1OCVIsopenicillin N synthase1.21.3.10.444
1mj3HXCEnoyl-CoA hydratase, mitochondrial4.2.1.170.444
1qjfACSIsopenicillin N synthase1.21.3.10.444
1rpwDIDHTH-type transcriptional regulator QacR/0.444
1w6jR71Lanosterol synthase5.4.99.70.444
1zaf789Estrogen receptor beta/0.444
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
2ol4JPNEnoyl-ACP reductase/0.444
3eel53TUncharacterized protein/0.444
3fl4FL4Mitogen-activated protein kinase 14/0.444
3owuEQUSteroid Delta-isomerase5.3.3.10.444
3pn1IVHDNA ligase/0.444
3q0gBCOProbable enoyl-CoA hydratase echA84.2.1.170.444
3q9oNADCholix toxin2.4.2.360.444
4bb2STRCorticosteroid-binding globulin/0.444
4bz7B3NHistone deacetylase/0.444
4h8i11WGlutamate receptor ionotropic, kainate 2/0.444
4jl5ADPAdenylate kinase/0.444
4la0198Serum albumin/0.444
4wevSUZAldo-keto reductase family 1 member B101.1.10.444
5h8tRTLRetinol-binding protein 1/0.444
1f4gTP4Thymidylate synthase/0.443
1fm1WAYCollagenase 33.4.240.443
1kzjCB3Thymidylate synthase/0.443
1mvtDTMDihydrofolate reductase1.5.1.30.443
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
1vkgCRIHistone deacetylase 83.5.1.980.443
1y6rMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.443
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.443
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.443
2opbF21Phenylethanolamine N-methyltransferase2.1.1.280.443
2p15EZTEstrogen receptor/0.443
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.443
3csoXNIGenome polyprotein2.7.7.480.443
3ekuCY9Actin-5C/0.443
3htjETEbrA repressor/0.443
3i68J4ZDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.443
3juqAKDPhenazine biosynthesis protein A/B/0.443
3k47D09Dihydrofolate reductase1.5.1.30.443
3tguWF3Cytochrome b/0.443
3thrC2FGlycine N-methyltransferase2.1.1.200.443
3up3XCAaceDAF-12/0.443
3v94WYQPhosphodiesterase/0.443
3wv9FEGHmd co-occurring protein HcgE/0.443
4bufF36Tankyrase-22.4.2.300.443
4jtqFLPAldo-keto reductase family 1 member C2/0.443
4kzl20DTankyrase-22.4.2.300.443
4n1fCZHObelin/0.443
4s1iPLPPyridoxal kinase, putative/0.443
1nueGDPNucleoside diphosphate kinase B2.7.4.60.442
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.442
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1yinCM3Estrogen receptor/0.442
2bjsACVIsopenicillin N synthase1.21.3.10.442
2c9bPUG6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2e0nSAHPrecorrin-2 C20-methyltransferase/0.442
2pl0STITyrosine-protein kinase Lck2.7.10.20.442
2trsIPLTryptophan synthase alpha chain/0.442
2vcxD26Hematopoietic prostaglandin D synthase/0.442
2ykjYKJHeat shock protein HSP 90-alpha/0.442
2zb8IMNProstaglandin reductase 21.3.1.480.442
3fu5492Leukotriene A-4 hydrolase3.3.2.60.442
3gncQQQGlutaryl-CoA dehydrogenase/0.442
3h3sH15Collagen type IV alpha-3-binding protein/0.442
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3lfeZ84Mitogen-activated protein kinase 14/0.442
3of1CMPcAMP-dependent protein kinase regulatory subunit/0.442
3ojxFMNNADPH--cytochrome P450 reductase/0.442
3qckNX5Receptor-type tyrosine-protein phosphatase gamma3.1.3.480.442
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.442
4blwSAHRibosomal RNA large subunit methyltransferase J/0.442
4e2zJHZMethyltransferase/0.442
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
4eiyZMAAdenosine receptor A2a/0.442
4g210VPVitamin D3 receptor A/0.442
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.442
4ib4ERM5-hydroxytryptamine receptor 2B/0.442
4iilRBFMembrane lipoprotein TpN38(b)/0.442
4iwv1J9Glucokinase2.7.1.20.442
4j6dTESCytochrome P450 monooxygenase/0.442
4l10A63Tankyrase-22.4.2.300.442
4p9dTMPDeoxycytidylate deaminase/0.442
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.442
5bp9SAHPutative methyltransferase protein/0.442
3ny8JRZBeta-2 adrenergic receptor/0.442
1a50FIPTryptophan synthase alpha chain/0.441
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.441
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.441
1x8lOXRRetinol dehydratase/0.441
1xkqNDPUncharacterized protein/0.441
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.441
2fpcSCGStrictosidine synthase4.3.3.20.441
2ga2A19Methionine aminopeptidase 2/0.441
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.441
2ok7A2PFerredoxin--NADP reductase, apicoplast/0.441
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.441
3eeiMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.441
3f0aACOSpermidine N(1)-acetyltransferase/0.441
3hywDCQSulfide-quinone reductase/0.441
3nx4NAPPutative oxidoreductase/0.441
3w0uHPWLactoylglutathione lyase4.4.1.50.441
4bfvZVVPantothenate kinase2.7.1.330.441
4e32DWNMethyltransferase/0.441
4iwc1GVEstrogen receptor/0.441
4j0p1H8Beta-secretase 13.4.23.460.441
4li81XQTankyrase-12.4.2.300.441
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.441
4pl9ADPEthylene receptor 1/0.441
4tyj0LIFibroblast growth factor receptor 42.7.10.10.441
5d6lCAUBeta-2 adrenergic receptor/0.441
3ny9JSZBeta-2 adrenergic receptor/0.441
1dfoFFOSerine hydroxymethyltransferase2.1.2.10.440
1dljUGAUDP-glucose 6-dehydrogenase/0.440
1dr4HBIDihydrofolate reductase1.5.1.30.440
1hfrMOTDihydrofolate reductase1.5.1.30.440
1pr0NOSPurine nucleoside phosphorylase DeoD-type/0.440
1u72MTXDihydrofolate reductase1.5.1.30.440
1uzwCDHIsopenicillin N synthase1.21.3.10.440
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.440
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.440
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2igyA2TPlasmepsin 2/0.440
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.440
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.440
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3lanKBTGag-Pol polyprotein2.7.7.490.440
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.440
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.440
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.440
4frjDWBBeta-secretase 13.4.23.460.440
4hmhF94Tankyrase-22.4.2.300.440
4ieiADPGene 2 protein/0.440
4isg1FYGlucokinase2.7.1.20.440
4msg2C6Tankyrase-12.4.2.300.440
4mxeACON-acetyltransferase ESCO12.3.10.440
4nv0MG77-methylguanosine phosphate-specific 5'-nucleotidase/0.440
4twnB96Ephrin type-A receptor 32.7.10.10.440
5ab6CAANonspecific lipid-transfer protein, putative/0.440
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.440