sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2v9x | DUT | dCTP deaminase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2v9x | DUT | dCTP deaminase | / | 1.000 | |
| 1xs4 | DCP | dCTP deaminase | / | 0.593 | |
| 4a6a | TTP | dCTP deaminase | 3.5.4.13 | 0.590 | |
| 4xjc | TTP | dCTP deaminase | / | 0.537 | |
| 3juq | AKD | Phenazine biosynthesis protein A/B | / | 0.507 | |
| 4gv8 | DUP | DUTPase | / | 0.504 | |
| 2qxx | TTP | dCTP deaminase | 3.5.4.13 | 0.500 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.499 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.497 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.495 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.492 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.491 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.490 | |
| 2hxd | DUP | dCTP deaminase, dUMP-forming | 3.5.4.30 | 0.489 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.487 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.484 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.483 | |
| 2bxq | IMN | Serum albumin | / | 0.481 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4pkw | GM6 | Lethal factor | 3.4.24.83 | 0.478 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.477 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.475 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.475 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.475 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.474 | |
| 3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 2bxm | IMN | Serum albumin | / | 0.473 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.473 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.472 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.472 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.470 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.470 | |
| 2hek | GDP | Uncharacterized protein | / | 0.470 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.469 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.469 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.469 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.469 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.469 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.468 | |
| 2j4q | TTP | dCTP deaminase | / | 0.468 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.468 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.468 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.467 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.467 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.466 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.466 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.466 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.466 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.466 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.466 | |
| 3rzp | PRF | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.466 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.466 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.466 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.465 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.465 | |
| 3gdv | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.465 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.464 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.464 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.464 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.464 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.463 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.463 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.463 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.463 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.463 | |
| 3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.463 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.463 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.462 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.462 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.462 | |
| 2vj7 | VG6 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.462 | |
| 3b9l | AZZ | Serum albumin | / | 0.462 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.462 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.462 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.461 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.461 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.461 | |
| 2vnm | CM8 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2we3 | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.461 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.461 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.460 | |
| 2p1p | IAC | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.460 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.460 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.460 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.460 | |
| 1mez | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.459 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.459 | |
| 3a6r | FMN | FMN-binding protein | / | 0.459 | |
| 3c4v | LIP | D-inositol 3-phosphate glycosyltransferase | 2.4.1.250 | 0.459 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.459 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.459 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.459 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.459 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.459 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.458 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.457 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2g1m | 4HG | Egl nine homolog 1 | / | 0.457 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.457 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.457 | |
| 2x3j | ATP | AcsD | / | 0.457 | |
| 2xvw | 9NR | Serum albumin | / | 0.457 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.457 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.456 | |
| 3c6n | 2S8 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.456 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.456 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.456 | |
| 4l0o | PLP | Cystathionine gamma-synthase | 2.5.1.48 | 0.456 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.455 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.455 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.455 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.455 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.455 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 3oxf | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.455 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.455 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.455 | |
| 5kbw | RBF | Riboflavin transporter RibU | / | 0.455 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.454 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.454 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.454 | |
| 2ol0 | DUD | DUTP pyrophosphatase | / | 0.454 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.454 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.454 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.454 | |
| 3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.454 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.454 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.454 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.453 | |
| 2xvv | 9DN | Serum albumin | / | 0.453 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.453 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.453 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.453 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.453 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.452 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.452 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.452 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1xr2 | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 2.1.1.14 | 0.452 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.452 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.452 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.452 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.452 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.452 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.452 | |
| 4wrk | DUP | DUTPase | / | 0.452 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.451 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.451 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.451 | |
| 3wqt | ANP | Cell division protein FtsA | / | 0.451 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.450 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 1vyq | DUX | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.450 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.450 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.450 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.450 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.450 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.450 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.450 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4cf2 | 3GM | Integrase | / | 0.450 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.450 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.449 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.449 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.449 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.449 | |
| 3l06 | SN0 | N-acetylornithine carbamoyltransferase | 2.1.3.9 | 0.449 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.449 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.448 | |
| 1oo5 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.448 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.448 | |
| 3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.448 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.448 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3ru0 | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.448 | |
| 4die | C5P | Cytidylate kinase | / | 0.448 | |
| 4idp | GNP | Atlastin-1 | 3.6.5 | 0.448 | |
| 4tkg | 09L | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.448 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.448 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.448 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 1hk2 | T44 | Serum albumin | / | 0.447 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.447 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.447 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.447 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1vgr | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.447 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.447 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.447 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.447 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.447 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.447 | |
| 4tla | ADP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.447 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.447 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.446 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.446 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1j78 | VDY | Vitamin D-binding protein | / | 0.446 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.446 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2vj9 | VG7 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
| 4ey2 | 0RM | Metallo-beta-lactamase type 2 | / | 0.446 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.446 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.446 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.446 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.445 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.445 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.445 | |
| 2pci | SAH | Diphthine synthase | / | 0.445 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.445 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.445 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.445 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.445 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4o1g | AGS | Adenosine kinase | 2.7.1.20 | 0.445 | |
| 4to3 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 1i2c | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.444 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.444 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.444 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.444 | |
| 2h2j | SFG | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.444 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.444 | |
| 2vnn | CM7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.444 | |
| 2zts | ADP | Uncharacterized protein | / | 0.444 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.444 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.444 | |
| 3nhy | A7B | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.444 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.444 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.444 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2aky | AP5 | Adenylate kinase | / | 0.443 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.443 | |
| 2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.443 | |
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.443 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.443 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.443 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3g11 | P9C | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.443 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.443 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.442 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.442 | |
| 1icv | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.442 | |
| 1o2e | ANN | Phospholipase A2 | 3.1.1.4 | 0.442 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.442 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.442 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.442 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.442 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.442 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.442 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.442 | |
| 3f10 | 8HG | 8-oxoguanine-DNA-glycosylase | / | 0.442 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.442 | |
| 3o8h | O8H | HTH-type transcriptional regulator EthR | / | 0.442 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4eyb | 0WO | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.442 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.442 | |
| 5hgc | HCY | Uncharacterized protein | / | 0.442 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.441 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.441 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.441 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 2pck | SAH | Diphthine synthase | / | 0.441 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3h3c | P1E | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.441 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.441 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 1ake | AP5 | Adenylate kinase | / | 0.440 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1c7o | PPG | Hemolysin | / | 0.440 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.440 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.440 | |
| 1gsf | EAA | Glutathione S-transferase A1 | 2.5.1.18 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.440 | |
| 1lwx | AZD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.440 | |
| 2e08 | SAH | Diphthine synthase | / | 0.440 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.440 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.440 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.440 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.440 | |
| 4boe | CLR | Japanin | / | 0.440 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.440 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.440 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.440 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.440 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.440 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 | |
| 5cvc | PLP | Serine racemase | / | 0.440 |