scPDB - Distribution of Binding site Similarity values of 2pdq entry / Site 1

PDB ID	HET	Uniprot Name	EC Number
2pdq	47D	Aldose reductase	1.1.1.21

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2pdq	47D	Aldose reductase	1.1.1.21	1.000
2pdf	ZST	Aldose reductase	1.1.1.21	0.749
2pdu	393	Aldose reductase	1.1.1.21	0.746
1iei	ZES	Aldose reductase	1.1.1.21	0.649
2dv0	ZST	Aldose reductase	1.1.1.21	0.639
3t42	3T4	Aldose reductase	1.1.1.21	0.634
1us0	LDT	Aldose reductase	1.1.1.21	0.631
2dux	ZST	Aldose reductase	1.1.1.21	0.623
1pwl	BFI	Aldose reductase	1.1.1.21	0.622
3ghr	LDT	Aldose reductase	1.1.1.21	0.622
3ghs	LDT	Aldose reductase	1.1.1.21	0.622
3lbo	LDT	Aldose reductase	1.1.1.21	0.621
3lz5	LDT	Aldose reductase	1.1.1.21	0.620
2pdn	47D	Aldose reductase	1.1.1.21	0.615
3ght	LDT	Aldose reductase	1.1.1.21	0.614
3lql	LDT	Aldose reductase	1.1.1.21	0.614
4gca	2X9	Aldose reductase	1.1.1.21	0.612
2i16	LDT	Aldose reductase	1.1.1.21	0.610
1t40	ID5	Aldose reductase	1.1.1.21	0.606
2fz9	ZST	Aldose reductase	1.1.1.21	0.604
2pdi	ZST	Aldose reductase	1.1.1.21	0.604
3ghu	LDT	Aldose reductase	1.1.1.21	0.604
2iki	388	Aldose reductase	1.1.1.21	0.603
2i17	LDT	Aldose reductase	1.1.1.21	0.602
1z89	62P	Aldose reductase	1.1.1.21	0.601
2hvo	ZST	Aldose reductase	1.1.1.21	0.601
1z3n	3NA	Aldose reductase	1.1.1.21	0.599
2qxw	LDT	Aldose reductase	1.1.1.21	0.595
3mb9	ZST	Aldose reductase	1.1.1.21	0.595
1zua	TOL	Aldo-keto reductase family 1 member B10	1.1.1	0.594
2ikj	393	Aldose reductase	1.1.1.21	0.593
3m4h	388	Aldose reductase	1.1.1.21	0.591
2pdc	393	Aldose reductase	1.1.1.21	0.589
2pzn	393	Aldose reductase	1.1.1.21	0.589
2hv5	ZST	Aldose reductase	1.1.1.21	0.588
2pdm	ZST	Aldose reductase	1.1.1.21	0.588
3ld5	LDT	Aldose reductase	1.1.1.21	0.588
3m64	393	Aldose reductase	1.1.1.21	0.588
3g5e	Q74	Aldose reductase	1.1.1.21	0.587
3m0i	ZST	Aldose reductase	1.1.1.21	0.587
2duz	ZST	Aldose reductase	1.1.1.21	0.584
2hvn	ZST	Aldose reductase	1.1.1.21	0.583
2pdh	47D	Aldose reductase	1.1.1.21	0.583
2pdx	ZST	Aldose reductase	1.1.1.21	0.582
2fz8	ZST	Aldose reductase	1.1.1.21	0.579
2pdg	47D	Aldose reductase	1.1.1.21	0.576
1frb	ZST	Aldose reductase-related protein 2	/	0.571
4yu1	53N	Aldose reductase	1.1.1.21	0.571
2pdl	TOL	Aldose reductase	1.1.1.21	0.570
3len	ZST	Aldose reductase	1.1.1.21	0.568
2fzb	TOL	Aldose reductase	1.1.1.21	0.565
2pdj	393	Aldose reductase	1.1.1.21	0.561
2pdb	ZST	Aldose reductase	1.1.1.21	0.558
1t41	ID5	Aldose reductase	1.1.1.21	0.557
2fzd	TOL	Aldose reductase	1.1.1.21	0.556
2pd5	ZST	Aldose reductase	1.1.1.21	0.542
1uho	VDN	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.540
3mc5	393	Aldose reductase	1.1.1.21	0.537
1ah3	TOL	Aldose reductase	1.1.1.21	0.535
5liu	388	Aldo-keto reductase family 1 member B10	1.1.1	0.529
2agt	FID	Aldose reductase	1.1.1.21	0.528
3v94	WYQ	Phosphodiesterase	/	0.528
1el3	I84	Aldose reductase	1.1.1.21	0.526
2pdp	393	Aldose reductase	1.1.1.21	0.523
1xor	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.521
2ikh	LIT	Aldose reductase	1.1.1.21	0.521
1oyn	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.516
4wev	SUZ	Aldo-keto reductase family 1 member B10	1.1.1	0.516
1rxj	BNI	Streptavidin	/	0.515
3g4k	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.513
2aot	2PM	Histamine N-methyltransferase	2.1.1.8	0.512
1xoq	ROF	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.510
2pdw	FID	Aldose reductase	1.1.1.21	0.506
4phl	PIL	Phosphodiesterase	/	0.504
4kp6	1S1	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.502
1xon	PIL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.501
2nvc	ITA	Aldose reductase	1.1.1.21	0.501
1zkn	IBM	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.500
1eko	I84	Aldose reductase	1.1.1.21	0.498
4lm4	JPZ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.498
3tvx	PNX	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	3.1.4.53	0.497
1pax	DHQ	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.495
1kyv	RBF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.494
3k4s	0MO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.494
4b13	X25	Glycylpeptide N-tetradecanoyltransferase	/	0.494
1h42	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.492
3vo2	FAD	Ferredoxin--NADP reductase	/	0.492
3wi2	P98	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.492
4fam	0SZ	Aldo-keto reductase family 1 member C3	/	0.492
3iak	EV1	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.491
3sl6	JN8	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.491
4i5x	FLF	Aldo-keto reductase family 1 member B10	1.1.1	0.491
1ah0	SBI	Aldose reductase	1.1.1.21	0.490
1y2e	5DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.490
2cbq	TH2	Neocarzinostatin	/	0.490
3aiv	HBO	4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic	3.2.1.182	0.490
3g58	988	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.490
4ajm	3A6	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.490
4dbw	511	Aldo-keto reductase family 1 member C3	/	0.490
4ddl	0JQ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.490
4kq6	DLZ	6,7-dimethyl-8-ribityllumazine synthase	/	0.490
4u16	3C0	Muscarinic acetylcholine receptor M3	/	0.490
1v08	NTZ	4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic	3.2.1.182	0.489
1y2b	DEE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.489
2c1z	KMP	Anthocyanidin 3-O-glucosyltransferase 2	2.4.1.115	0.489
4a7y	NHF	Aldos-2-ulose dehydratase	/	0.489
1tbb	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.488
3v35	NTI	Aldose reductase	1.1.1.21	0.488
4ia0	5BB	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.488
2xuf	TZ4	Acetylcholinesterase	3.1.1.7	0.487
3aiq	HBO	4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic	3.2.1.182	0.487
1e1f	PSG	4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic	3.2.1.182	0.486
1q9m	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.486
1ro6	ROL	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.486
1y2c	3DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.486
2f2k	TGG	Aldose reductase	1.1.1.21	0.486
3cas	ASD	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.486
3p2v	DOY	Aldose reductase	1.1.1.21	0.486
3w5e	NVW	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.486
4heu	15J	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.486
3g4i	D71	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.485
3sl8	JN7	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.485
3f3y	4OA	Bile salt sulfotransferase	2.8.2.14	0.484
2o8h	227	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.482
3u2c	SUZ	Aldose reductase	1.1.1.21	0.482
4ajd	F04	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.482
1que	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.481
2w6q	OA5	Biotin carboxylase	6.3.4.14	0.481
3jsx	CC2	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.481
3ocw	3AM	Lipoprotein E	/	0.481
2y04	68H	Beta-1 adrenergic receptor	/	0.481
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.480
1zkl	IBM	High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	3.1.4.53	0.480
2f38	15M	Aldo-keto reductase family 1 member C3	/	0.480
3bjc	WAN	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.480
3zj7	C1K	Strictosidine-O-beta-D-glucosidase	3.2.1.105	0.480
1ogj	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.479
1xom	CIO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.479
4c1i	EH9	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.479
4g2w	NI0	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.479
4llk	MEW	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.479
4myq	19T	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.479
1s36	CEI	Obelin	/	0.478
1sm4	FAD	Ferredoxin--NADP reductase	/	0.478
3nyt	ULP	UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase	2.6.1.98	0.478
4b12	C23	Glycylpeptide N-tetradecanoyltransferase	/	0.478
1gjr	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.477
2i65	NAD	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	3.2.2.6	0.477
2y1x	845	Histone-arginine methyltransferase CARM1	/	0.477
3g4g	D71	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.477
4f1l	0RY	Poly [ADP-ribose] polymerase 14	2.4.2.30	0.477
4jpg	1OX	Pyruvate kinase PKM	2.7.1.40	0.477
4oex	5EO	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.477
4std	BFS	Scytalone dehydratase	4.2.1.94	0.477
1esm	COA	Pantothenate kinase	2.7.1.33	0.476
1ry8	RUT	Aldo-keto reductase family 1 member C3	/	0.476
1y2k	7DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.476
2cek	N8T	Acetylcholinesterase	3.1.1.7	0.476
2xi4	AFT	Acetylcholinesterase	3.1.1.7	0.476
3zc3	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.476
4b65	NDP	L-ornithine N(5)-monooxygenase	/	0.476
1e62	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.475
3af2	ACP	Pantothenate kinase	2.7.1.33	0.475
1eve	E20	Acetylcholinesterase	3.1.1.7	0.474
1yw7	A41	Methionine aminopeptidase 2	/	0.474
2aov	C2M	Histamine N-methyltransferase	2.1.1.8	0.474
2f98	NGV	Aklanonic acid methyl ester cyclase AcmA	5.5.1.23	0.474
2fm5	M99	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.474
4hf4	15H	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.474
4j7h	TRH	PCZA361.3	/	0.474
4u14	0HK	Muscarinic acetylcholine receptor M3	/	0.474
1y2d	4DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.473
2xup	TZ5	Acetylcholinesterase	3.1.1.7	0.473
3d3p	20A	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.473
3dz7	O8M	S-adenosylmethionine decarboxylase proenzyme	4.1.1.50	0.473
2geu	COK	Pantothenate kinase	2.7.1.33	0.472
3uzz	TES	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.472
4b11	7I1	Glycylpeptide N-tetradecanoyltransferase	/	0.472
1bjk	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.471
2c2b	SAM	Threonine synthase 1, chloroplastic	4.2.3.1	0.471
3o56	ZG1	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.471
3sni	546	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.471
5dsg	0HK	Muscarinic acetylcholine receptor M4	/	0.471
1aqu	EST	Estrogen sulfotransferase, testis isoform	2.8.2.4	0.470
1pj6	FOL	Dimethylglycine oxidase	1.5.3.10	0.470
1y60	H4M	5,6,7,8-tetrahydromethanopterin hydro-lyase	4.2.1.147	0.470
2gg0	U11	Methionine aminopeptidase	/	0.470
2vt4	P32	Beta-1 adrenergic receptor	/	0.470
3b9g	IMH	IAG-nucleoside hydrolase	/	0.470
4af6	FAD	Ferredoxin--NADP reductase, leaf isozyme, chloroplastic	1.18.1.2	0.470
5cxv	0HK	Muscarinic acetylcholine receptor M1	/	0.470
1umc	TDP	2-oxoisovalerate dehydrogenase subunit alpha	1.2.4.4	0.469
1umc	TDP	2-oxoisovalerate dehydrogenase subunit beta	1.2.4.4	0.469
2hzq	STR	Apolipoprotein D	/	0.469
4n3r	2GU	Tankyrase-1	2.4.2.30	0.469
1gpn	HUB	Acetylcholinesterase	3.1.1.7	0.468
3cv6	HXS	Aldo-keto reductase family 1 member C21	/	0.468
3zj6	VM2	Raucaffricine-O-beta-D-glucosidase	3.2.1.125	0.468
4fcb	0T7	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.468
2fm0	M98	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.467
2pdy	FID	Aldose reductase	1.1.1.21	0.467
3aez	GDP	Pantothenate kinase	2.7.1.33	0.467
3s3g	TLT	Aldose reductase	1.1.1.21	0.467
4i9z	5BA	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.467
4mm7	29J	Na(+):neurotransmitter symporter (Snf family)	/	0.467
1dia	L24	C-1-tetrahydrofolate synthase, cytoplasmic	1.5.1.5	0.466
1e66	HUX	Acetylcholinesterase	3.1.1.7	0.466
1soj	IBM	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	3.1.4.17	0.466
1u65	CP0	Acetylcholinesterase	3.1.1.7	0.466
1udt	VIA	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.466
2zev	IPE	Geranylgeranyl pyrophosphate synthase	/	0.466
3g4l	ROF	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.466
3nu0	3TU	Dihydrofolate reductase	1.5.1.3	0.466
3qpn	PFK	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.466
4ga8	SBI	Aldo-keto reductase family 1 member B10	1.1.1	0.466
4gv0	8ME	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.466
4paa	THG	Dimethylglycine dehydrogenase, mitochondrial	1.5.8.4	0.466
1lnm	DTX	Bilin-binding protein	/	0.465
1s2c	FLF	Aldo-keto reductase family 1 member C3	/	0.465
2ct8	MSP	Methionine--tRNA ligase	6.1.1.10	0.465
2gmv	UN8	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.465
2xuh	TZ4	Acetylcholinesterase	3.1.1.7	0.465
3af4	GCP	Pantothenate kinase	2.7.1.33	0.465
3n3z	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.465
3ocx	2AM	Lipoprotein E	/	0.465
3ny8	JRZ	Beta-2 adrenergic receptor	/	0.465
1h22	E10	Acetylcholinesterase	3.1.1.7	0.464
1isg	AGS	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2	3.2.2.6	0.464
1mcz	RMN	Benzoylformate decarboxylase	4.1.1.7	0.464
2a59	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.464
2get	COK	Pantothenate kinase	2.7.1.33	0.464
2zsb	ADP	Pantothenate kinase	2.7.1.33	0.464
3qpp	PFW	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.464
4g2j	0WF	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.464
4pab	THG	Dimethylglycine dehydrogenase, mitochondrial	1.5.8.4	0.464
5a4w	QCT	Glutathione S-transferase F2	2.5.1.18	0.464
2ycx	P32	Beta-1 adrenergic receptor	/	0.464
1ihi	IU5	Aldo-keto reductase family 1 member C2	/	0.463
1w87	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.463
2bjs	ACV	Isopenicillin N synthase	1.21.3.1	0.463
2y1w	849	Histone-arginine methyltransferase CARM1	/	0.463
3ppk	FNI	Serine/threonine-protein kinase B-raf	2.7.11.1	0.463
4fap	ARD	Peptidyl-prolyl cis-trans isomerase FKBP1A	5.2.1.8	0.463
4fap	ARD	Serine/threonine-protein kinase mTOR	2.7.11.1	0.463
1e63	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.462
1odn	APV	Isopenicillin N synthase	1.21.3.1	0.462
1qv0	CZH	Obelin	/	0.462
2qx7	NAP	Eugenol synthase 1	1.1.1.318	0.462
2xuj	TZ5	Acetylcholinesterase	3.1.1.7	0.462
2yne	YNE	Glycylpeptide N-tetradecanoyltransferase	/	0.462
3c1o	NAP	Eugenol synthase	/	0.462
3c49	KU8	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.462
4a1o	AMZ	Bifunctional purine biosynthesis protein PurH	2.1.2.3	0.462
4af7	FAD	Ferredoxin--NADP reductase, leaf isozyme, chloroplastic	1.18.1.2	0.462
4bbh	YBN	Glycylpeptide N-tetradecanoyltransferase	/	0.462
4bfw	ZVW	Pantothenate kinase	2.7.1.33	0.462
4gv4	MEJ	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.462
4hmn	16J	Aldo-keto reductase family 1 member C3	/	0.462
4kn1	04J	Folate receptor beta	/	0.462
1gaq	FAD	Ferredoxin	/	0.461
1gm8	SOX	Penicillin G acylase	3.5.1.11	0.461
1mab	ADP	ATP synthase subunit beta, mitochondrial	3.6.3.14	0.461
3hgg	CHD	CmeR	/	0.461
3r8h	ZOM	Aldo-keto reductase family 1 member C3	/	0.461
3uwe	VJJ	Aldo-keto reductase family 1 member C3	/	0.461
4mdk	U94	Ubiquitin-conjugating enzyme E2 R1	/	0.461
1p0p	BCH	Cholinesterase	3.1.1.8	0.460
1ro9	8BR	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.460
1s9d	AFB	Cytohesin-2	/	0.460
1s9d	AFB	ADP-ribosylation factor 1	/	0.460
1x1c	SAH	C-20 methyltransferase	/	0.460
2bd0	BIO	Sepiapterin reductase	/	0.460
3gn7	3GN	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.460
3uzx	AOM	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.460
4cdm	FO1	Deoxyribodipyrimidine photolyase	/	0.460
4kfj	FOL	Dihydrofolate reductase	1.5.1.3	0.460
4lcn	GNG	Cytidine and deoxycytidylate deaminase zinc-binding region	/	0.460
4xo7	ASD	Aldo-keto reductase family 1 member C2	/	0.460
5d6l	CAU	Beta-2 adrenergic receptor	/	0.460
1w4l	GL8	Acetylcholinesterase	3.1.1.7	0.459
1xf0	ASD	Aldo-keto reductase family 1 member C3	/	0.459
1zgc	A2E	Acetylcholinesterase	3.1.1.7	0.459
2rqf	JH3	Hemolymph juvenile hormone binding protein	/	0.459
2w6c	BM4	Acetylcholinesterase	3.1.1.7	0.459
2wmd	ZZ0	NmrA-like family domain-containing protein 1	/	0.459
2zu9	GDP	Mannosyl-3-phosphoglycerate synthase	2.4.1.217	0.459
4bjb	P34	Tankyrase-2	2.4.2.30	0.459
4mrx	CZH	Obelin	/	0.459
4n3l	2FN	Prothrombin	3.4.21.5	0.459
4daj	0HK	Muscarinic acetylcholine receptor M3	/	0.459
1akc	PPE	Aspartate aminotransferase, mitochondrial	2.6.1.1	0.458
1dig	L37	C-1-tetrahydrofolate synthase, cytoplasmic	1.5.1.5	0.458
1dx6	GNT	Acetylcholinesterase	3.1.1.7	0.458
1ry0	PG2	Aldo-keto reductase family 1 member C3	/	0.458
2aou	CQA	Histamine N-methyltransferase	2.1.1.8	0.458
2cmf	F11	Acetylcholinesterase	3.1.1.7	0.458
4jtq	FLP	Aldo-keto reductase family 1 member C2	/	0.458
1mrq	STR	Aldo-keto reductase family 1 member C1	/	0.457
1oj4	CDM	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	2.7.1.148	0.457
2vdy	HCY	Corticosteroid-binding globulin	/	0.457
3hmv	HBT	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.457
4jq4	IMN	Aldo-keto reductase family 1 member C2	/	0.457
1ogi	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.456
1qgz	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.456
1zq5	E04	Aldo-keto reductase family 1 member C3	/	0.456
2iqd	LPA	Aldose reductase	1.1.1.21	0.456
3biz	61E	Wee1-like protein kinase	2.7.10.2	0.456
3dz6	M8E	S-adenosylmethionine decarboxylase proenzyme	4.1.1.50	0.456
3ojw	FMN	NADPH--cytochrome P450 reductase	/	0.456
3w2e	FAD	NADH-cytochrome b5 reductase 3	1.6.2.2	0.456
4kmz	FOL	Folate receptor beta	/	0.456
4rxp	DTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.456
5bp7	SAH	SAM-dependent methyltransferase	/	0.456
5d5a	CAU	Beta-2 adrenergic receptor	/	0.456
5d5b	CAU	Beta-2 adrenergic receptor	/	0.456
1pwm	FID	Aldose reductase	1.1.1.21	0.455
2inz	OHP	Aldose reductase	1.1.1.21	0.455
2ovv	PFH	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.455
3hbf	MYC	Flavonoid 3-O-glucosyltransferase	2.4.1	0.455
3k3h	BYE	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.455
3t0k	DCQ	Sulfide-quinone reductase	/	0.455
4b14	4XB	Glycylpeptide N-tetradecanoyltransferase	/	0.455
4bjc	RPB	Tankyrase-2	2.4.2.30	0.455
4dbu	BT9	Aldo-keto reductase family 1 member C3	/	0.455
4dk7	0KS	Oxysterols receptor LXR-beta	/	0.455
4jtr	IZP	Aldo-keto reductase family 1 member C2	/	0.455
1lkd	BP6	Biphenyl-2,3-diol 1,2-dioxygenase	1.13.11.39	0.454
1rvv	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.454
1w76	GNT	Acetylcholinesterase	3.1.1.7	0.454
1yw8	A75	Methionine aminopeptidase 2	/	0.454
2rcw	AAI	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.454
2zsa	ADP	Pantothenate kinase	2.7.1.33	0.454
3dyn	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.454
3zec	ANP	Adenosine monophosphate-protein transferase SoFic	2.7.7.n1	0.454
4bb6	HD1	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.454
4gh6	LUO	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.454
4xwt	U5P	Ribonuclease J	/	0.454
5c1g	GDU	Histo-blood group ABO system transferase	/	0.454
1go2	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.453
1nqu	RDL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.453
1so2	666	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	3.1.4.17	0.453
2jf6	S55	Strictosidine-O-beta-D-glucosidase	3.2.1.105	0.453
2rc6	FAD	Ferredoxin--NADP reductase	/	0.453
3dys	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.453
3gx9	TXD	Morphinone reductase	/	0.453
4g2y	NI5	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.453
4lrh	FOL	Folate receptor alpha	/	0.453
4tnz	TTP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.453
2ycz	I32	Beta-1 adrenergic receptor	/	0.453
2gms	P0P	Putative pyridoxamine 5-phosphate-dependent dehydrase	/	0.452
2vf3	GVS	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.452
3c1k	T15	Prothrombin	3.4.21.5	0.452
3c4h	DRL	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.452
3szf	DCQ	Sulfide-quinone reductase	/	0.452
4c71	7RD	3-oxoacyl-ACP synthase	/	0.452
4d1o	H4B	Nitric oxide synthase, endothelial	1.14.13.39	0.452
4ey7	E20	Acetylcholinesterase	3.1.1.7	0.452
4gv2	5ME	Poly [ADP-ribose] polymerase 3	2.4.2.30	0.452
5epe	SAH	Uncharacterized protein	/	0.452
1ut6	A8N	Acetylcholinesterase	3.1.1.7	0.451
1yw9	A84	Methionine aminopeptidase 2	/	0.451
2evm	FC2	Methionine aminopeptidase	/	0.451
2qim	ZEA	Class 10 plant pathogenesis-related protein	/	0.451
2zoz	ET	Transcriptional regulator	/	0.451
3bur	TES	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.451
3dyl	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.451
3jsi	WTC	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.451
3o76	GTB	Glutathione S-transferase P 1	2.5.1.18	0.451
3sn7	540	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.451
4bfu	ZVU	Pantothenate kinase	2.7.1.33	0.451
4bpr	FAD	Ferredoxin--NADP reductase	1.18.1.2	0.451
4dbs	0HV	Aldo-keto reductase family 1 member C3	/	0.451
4glx	0XS	DNA ligase	6.5.1.2	0.451
4jq2	SUZ	Aldo-keto reductase family 1 member C2	/	0.451
4xoq	F42	Coenzyme F420:L-glutamate ligase	/	0.451
3uon	QNB	Muscarinic acetylcholine receptor M2	/	0.451
1fwy	UD1	Bifunctional protein GlmU	/	0.450
1sqi	869	4-hydroxyphenylpyruvate dioxygenase	/	0.450
1w6r	GNT	Acetylcholinesterase	3.1.1.7	0.450
1z5u	CMP	Class B acid phosphatase	/	0.450
2v5u	FMN	Flavodoxin	/	0.450
2y0j	AXC	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.450
3c3x	NAP	Eugenol synthase 1	1.1.1.318	0.450
3g72	A6T	Renin	3.4.23.15	0.450
3l3m	A92	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.450
3ug8	IMN	Aldo-keto reductase family 1 member C3	/	0.450
4a95	9MT	Glycylpeptide N-tetradecanoyltransferase	/	0.450
4ajf	F03	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.450
4jvm	XDI	Estrogen sulfotransferase	2.8.2.4	0.450
5cc9	DDF	Dihydrofolate reductase	1.5.1.3	0.450
5flj	QUE	Quercetinase QueD	/	0.450
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.449
1odj	GMP	Purine nucleoside phosphorylase	/	0.449
1rkw	PNT	HTH-type transcriptional regulator QacR	/	0.449
2ouy	CMP	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.449
2ovy	PFJ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.449
2qw8	NAP	Eugenol synthase 1	1.1.1.318	0.449
2wey	EV1	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.449
3ggs	2FD	Purine nucleoside phosphorylase	2.4.2.1	0.449
4h0x	NAD	Iota toxin component Ia	/	0.449
4hhy	15R	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.449
5c1m	CLR	Mu-type opioid receptor	/	0.449
1el4	CTZ	Obelin	/	0.448
1gt5	BZQ	Odorant-binding protein	/	0.448
1rpw	DID	HTH-type transcriptional regulator QacR	/	0.448
1tfz	869	4-hydroxyphenylpyruvate dioxygenase	1.13.11.27	0.448
2b01	TUD	Phospholipase A2, major isoenzyme	3.1.1.4	0.448
2z2w	770	Wee1-like protein kinase	2.7.10.2	0.448
3dr7	GPD	GDP-perosamine synthase	/	0.448
4li6	1XO	Tankyrase-1	2.4.2.30	0.448
4mrm	2BY	Gamma-aminobutyric acid type B receptor subunit 1	/	0.448
4nwi	CTN	7-methylguanosine phosphate-specific 5'-nucleotidase	/	0.448
1bh5	GTX	Lactoylglutathione lyase	4.4.1.5	0.447
1by5	GLY_GLY_GLY_AHO_AHO_AHO_FE	Ferrichrome-iron receptor	/	0.447
1ef3	FID	Aldose reductase	1.1.1.21	0.447
1nsg	RAD	Peptidyl-prolyl cis-trans isomerase FKBP1A	5.2.1.8	0.447
1nsg	RAD	Serine/threonine-protein kinase mTOR	2.7.11.1	0.447
1ps9	MDE	2,4-dienoyl-CoA reductase	1.3.1.34	0.447
2a57	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.447
2ea4	F79	Methionine aminopeptidase 2	/	0.447
2psj	CEI	Renilla-luciferin 2-monooxygenase	1.13.12.5	0.447
2w3m	FOL	Dihydrofolate reductase	1.5.1.3	0.447
2x1l	ADN	Methionine--tRNA ligase	/	0.447
3ele	PLP	Aminotransferase	/	0.447
3esz	FMN	Flavodoxin	/	0.447
3fsj	D7K	Benzoylformate decarboxylase	4.1.1.7	0.447
3h3r	14H	Collagen type IV alpha-3-binding protein	/	0.447
3nub	UD0	UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase	2.6.1.98	0.447
3wav	DWV	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2	3.1.4.39	0.447
4e0u	0MV	Cyclic dipeptide N-prenyltransferase	/	0.447
4wbd	ADP	Putative cysteine ligase BshC	/	0.447
2rh1	CAU	Beta-2 adrenergic receptor	/	0.447
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.446
1gaw	FAD	Ferredoxin	/	0.446
1i5r	HYC	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.446
1zgb	A1E	Acetylcholinesterase	3.1.1.7	0.446
2fjm	073	Tyrosine-protein phosphatase non-receptor type 1	3.1.3.48	0.446
2gpv	OHT	Estrogen-related receptor gamma	/	0.446
2i0z	FAD	NAD(FAD)-utilizing dehydrogenases	/	0.446
2is7	2CL	Aldose reductase	1.1.1.21	0.446
2vcz	VC3	Hematopoietic prostaglandin D synthase	/	0.446
2xlt	NA0	Putative flavin-containing monooxygenase	/	0.446
3dyq	PCG	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.446
3epx	IMQ	IAG-nucleoside hydrolase	/	0.446
3g45	988	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.446
3iu9	T07	Methionine aminopeptidase 2	/	0.446
3u5y	SCG	Raucaffricine-O-beta-D-glucosidase	3.2.1.125	0.446
4ey6	GNT	Acetylcholinesterase	3.1.1.7	0.446
4mt9	2D6	Tankyrase-1	2.4.2.30	0.446
1bx0	FAD	Ferredoxin--NADP reductase, chloroplastic	1.18.1.2	0.445
1eno	NAD	Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic	1.3.1.9	0.445
1odc	A8B	Acetylcholinesterase	3.1.1.7	0.445
1uhh	CZP	Aequorin-2	/	0.445
1w6j	R71	Lanosterol synthase	5.4.99.7	0.445
1x1b	SAH	C-20 methyltransferase	/	0.445
2ga2	A19	Methionine aminopeptidase 2	/	0.445
2gyw	OBI	Acetylcholinesterase	3.1.1.7	0.445
2ipj	FFA	Aldo-keto reductase family 1 member C2	/	0.445
2qcx	PF1	Aminopyrimidine aminohydrolase	/	0.445
2vrj	NCW	Beta-glucosidase A	3.2.1.21	0.445
3cr0	809	Wee1-like protein kinase	2.7.10.2	0.445
3g49	3G4	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.445
3h0w	N8M	S-adenosylmethionine decarboxylase proenzyme	4.1.1.50	0.445
3jq8	DX3	Pteridine reductase, putative	/	0.445
3lzz	GDP	Uncharacterized protein	/	0.445
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.445
3tfj	THG	Dimethylsulfonioproprionate demethylase DmdA	2.1.1.269	0.445
3uzx	AOX	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.445
3zho	FMN	NAD(P)H dehydrogenase (quinone)	/	0.445
3zpq	XF5	Beta-1 adrenergic receptor	/	0.445
4g2l	0WL	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.445
2gg2	U12	Methionine aminopeptidase	/	0.444
2gl0	ADN	Uncharacterized protein	/	0.444
2uxo	TAC	HTH-type transcriptional regulator TtgR	/	0.444
2vz0	D64	Pteridine reductase	/	0.444
3acy	702	Dehydrosqualene synthase	/	0.444
3d2d	REN	Reticuline oxidase	1.21.3.3	0.444
3fvu	IAC	Kynurenine--oxoglutarate transaminase 1	2.6.1.7	0.444
3gjw	GJW	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.444
3wd9	QPC	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.444
4a16	H34	Acetylcholinesterase	3.1.1.7	0.444
4arb	C57	Acetylcholinesterase	3.1.1.7	0.444
4bvn	P32	Beta-1 adrenergic receptor	/	0.444
4c73	TLH	3-oxoacyl-ACP synthase	/	0.444
4kn0	MTX	Folate receptor beta	/	0.444
1p91	SAM	23S rRNA (guanine(745)-N(1))-methyltransferase	/	0.443
1qv1	CZH	Obelin	/	0.443
1yci	NDF	Hypoxia-inducible factor 1-alpha inhibitor	1.14.11.30	0.443
2cl5	BIE	Catechol O-methyltransferase	2.1.1.6	0.443
2v58	LZJ	Biotin carboxylase	6.3.4.14	0.443
3ghv	GHC	Dihydrofolate reductase	1.5.1.3	0.443
3iu7	FCD	Methionine aminopeptidase 2	/	0.443
3qft	FAD	NADPH--cytochrome P450 reductase	/	0.443
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.443
4to1	DCP	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.443
4xsv	C5P	Ethanolamine-phosphate cytidylyltransferase	2.7.7.14	0.443
4yfy	0FX	VioF	/	0.443
4zzi	1NS	NAD-dependent protein deacetylase sirtuin-1	3.5.1	0.443
5cto	NTD	4-hydroxyphenylpyruvate dioxygenase	1.13.11.27	0.443
1fnb	FAD	Ferredoxin--NADP reductase, chloroplastic	1.18.1.2	0.442
1t47	NTD	4-hydroxyphenylpyruvate dioxygenase	1.13.11.27	0.442
1uhj	CZB	Aequorin-2	/	0.442
2b04	CHO	Phospholipase A2, major isoenzyme	3.1.1.4	0.442
2ipw	2CL	Aldose reductase	1.1.1.21	0.442
3c27	DKK	Prothrombin	3.4.21.5	0.442
3gey	P34	Poly [ADP-ribose] polymerase 15	2.4.2.30	0.442
3htj	ET	EbrA repressor	/	0.442
3q7f	ED2	Uncharacterized protein	/	0.442
3u57	DH8	Raucaffricine-O-beta-D-glucosidase	3.2.1.125	0.442
4dyn	0MR	Nucleoprotein	/	0.442
4dyp	0MS	Nucleoprotein	/	0.442
4jhi	EMU	Nodulin-13	/	0.442
4kn2	LYA	Folate receptor beta	/	0.442
1fml	RTL	Retinol dehydratase	/	0.441
2d06	EST	Sulfotransferase 1A1	2.8.2.1	0.441
2e8u	IPE	Geranylgeranyl pyrophosphate synthase	/	0.441
2puc	GUN	HTH-type transcriptional repressor PurR	/	0.441
2v34	CTN	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	/	0.441
2xug	TZ4	Acetylcholinesterase	3.1.1.7	0.441
2xuo	TZ4	Acetylcholinesterase	3.1.1.7	0.441
3frk	TQP	QdtB	/	0.441
3l9m	L9M	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
3rj0	BLD	Protein BRASSINOSTEROID INSENSITIVE 1	2.7.10.1	0.441
3s8p	SAM	Histone-lysine N-methyltransferase KMT5B	2.1.1.43	0.441
4fll	YZ6	Methionine aminopeptidase 1	/	0.441
4rxq	DUT	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	3.1.5	0.441
1bx1	FAD	Ferredoxin--NADP reductase, chloroplastic	1.18.1.2	0.440
1d3d	BZT	Prothrombin	3.4.21.5	0.440
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.440
1q23	FUA	Chloramphenicol acetyltransferase	2.3.1.28	0.440
1sjw	NGV	Nogalonic acid methyl ester cyclase	/	0.440
1toi	HCI	Aspartate aminotransferase	2.6.1.1	0.440
1vzd	CB3	Thymidylate synthase	/	0.440
2fap	RAD	Peptidyl-prolyl cis-trans isomerase FKBP1A	5.2.1.8	0.440
2fap	RAD	Serine/threonine-protein kinase mTOR	2.7.11.1	0.440
2io6	330	Wee1-like protein kinase	2.7.10.2	0.440
2ipi	AKY	Aclacinomycin-N/aclacinomycin-A oxidase	/	0.440
2ok8	FAD	Ferredoxin--NADP reductase, apicoplast	/	0.440
2ouu	35G	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.440
2vp2	DGT	Deoxynucleoside kinase	/	0.440
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.440
2z7g	EH9	Adenosine deaminase	3.5.4.4	0.440
3af3	GCP	Pantothenate kinase	2.7.1.33	0.440
3dyl	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.440
3n39	FMN	Protein NrdI	/	0.440
3qfc	FAD	NADPH--cytochrome P450 reductase	/	0.440
3std	MQ0	Scytalone dehydratase	4.2.1.94	0.440
3voi	RCB	Glucanase	/	0.440
3zht	TD9	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.440
3zv7	NHG	Acetylcholinesterase	3.1.1.7	0.440
4ajg	F07	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.440
4b67	NAP	L-ornithine N(5)-monooxygenase	/	0.440
4bup	SAM	Histone-lysine N-methyltransferase KMT5B	2.1.1.43	0.440
4jq1	NPS	Aldo-keto reductase family 1 member C2	/	0.440
4mvh	2F5	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.440
4twn	B96	Ephrin type-A receptor 3	2.7.10.1	0.440
4xp4	COC	Sodium-dependent dopamine transporter	/	0.440