sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 1.000 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.707 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.675 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.594 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.574 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.566 | |
| 1hzj | UD1 | UDP-glucose 4-epimerase | / | 0.523 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.517 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.506 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.506 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.496 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.494 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.494 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.492 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.489 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.489 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.487 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.487 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.486 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.485 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.483 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.483 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.483 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.482 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.482 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.482 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.481 | |
| 3a3g | DLZ | Lumazine protein | / | 0.480 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.480 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.480 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.480 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.478 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.478 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.477 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.477 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.475 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.475 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.473 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.473 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.473 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.471 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.470 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.469 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.469 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.468 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.468 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.467 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.466 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.466 | |
| 1eq2 | ADQ | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.465 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.465 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.465 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.464 | |
| 1q43 | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.464 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.464 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.464 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.464 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.464 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.463 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.463 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.463 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.463 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.463 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 1lrk | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.462 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.462 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.462 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.462 | |
| 5dp2 | NAP | CurF | / | 0.462 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.461 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.461 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.461 | |
| 4jic | FMN | GTN Reductase | / | 0.461 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.461 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.460 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.460 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.460 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.459 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.459 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.459 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.459 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.459 | |
| 5a3b | APR | SIR2 family protein | / | 0.459 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.458 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.458 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.458 | |
| 2dsg | SAH | Diphthine synthase | / | 0.458 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.458 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.458 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.458 | |
| 1r2j | FAD | FkbI | / | 0.457 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.457 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.457 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.457 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.457 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.457 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.457 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.457 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.456 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.456 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.456 | |
| 2ejz | SAH | Diphthine synthase | / | 0.456 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.456 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.455 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.455 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.455 | |
| 5aga | ANP | DNA polymerase theta | / | 0.455 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.454 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.454 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.454 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.454 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.454 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.454 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.453 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.453 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.453 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.453 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.452 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.452 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.452 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.452 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.452 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.452 | |
| 3sop | GDP | Neuronal-specific septin-3 | / | 0.452 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.452 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.452 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.452 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.452 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.451 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 2udp | UPP | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.451 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.451 | |
| 3dm5 | GDP | Signal recognition particle 54 kDa protein | / | 0.451 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.451 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3u9e | COA | Lmo1369 protein | / | 0.451 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.451 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.451 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.450 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.450 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.450 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.450 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.450 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.450 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.450 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.450 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.450 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.449 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.449 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.449 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.449 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.449 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.449 | |
| 3zuy | TCH | Transporter | / | 0.449 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.449 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.449 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.448 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.448 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.448 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.448 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.448 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.448 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.448 | |
| 5a3c | NAD | SIR2 family protein | / | 0.448 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.448 | |
| 1gqt | ACP | Ribokinase | / | 0.447 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.447 | |
| 1i3m | UD1 | UDP-glucose 4-epimerase | / | 0.447 | |
| 2huv | SAH | Diphthine synthase | / | 0.447 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.447 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.447 | |
| 3fcc | ATP | D-alanine--poly(phosphoribitol) ligase subunit 1 | / | 0.447 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.447 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4dja | FAD | (6-4) photolyase | / | 0.447 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.447 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.446 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.446 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.446 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3ahn | 3A1 | Oligopeptidase | / | 0.446 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.446 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.446 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.446 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.445 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.445 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.445 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 3bmo | NAP | Pteridine reductase | / | 0.445 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.445 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.445 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.445 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.444 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.444 | |
| 2ejk | SAH | Diphthine synthase | / | 0.444 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.444 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.444 | |
| 2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.444 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.444 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.444 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3ge6 | FMN | Nitroreductase | / | 0.444 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.444 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.444 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.444 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.444 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.443 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.443 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.443 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.443 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.443 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.443 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.443 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.443 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.443 | |
| 4blr | UTP | NTPase P4 | / | 0.443 | |
| 4die | C5P | Cytidylate kinase | / | 0.443 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.443 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.442 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.442 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2e17 | SAH | Diphthine synthase | / | 0.442 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.442 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.442 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.442 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.442 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.442 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.442 | |
| 3wag | TYD | Glycosyltransferase | / | 0.442 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.442 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.442 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.441 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.441 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.441 | |
| 1wng | SAH | Diphthine synthase | / | 0.441 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.441 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.441 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.441 | |
| 2owg | SAH | Diphthine synthase | / | 0.441 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.441 | |
| 3cin | NAD | Myo-inositol-1-phosphate synthase-related protein | / | 0.441 | |
| 3e6e | DCS | Alanine racemase | / | 0.441 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3mje | NDP | AmphB | / | 0.441 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.441 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.441 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.440 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.440 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.440 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.440 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.440 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.440 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3e8x | NAP | BH1520 protein | / | 0.440 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.440 | |
| 4e2d | FMN | Dehydrogenase | / | 0.440 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.440 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.440 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.440 |