sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 1.292 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.966 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.916 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.863 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.861 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.854 | |
| 2qa1 | FAD | PgaE | / | 0.848 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.847 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.837 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.836 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.836 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.830 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.830 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.828 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.826 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.825 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.824 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.823 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.822 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.822 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.819 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.819 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.818 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.818 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.816 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.816 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.815 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.813 | |
| 4cnk | FAD | L-amino acid oxidase | / | 0.813 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.813 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.813 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.811 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.811 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.810 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.810 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.806 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.806 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.803 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.802 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.800 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.800 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.799 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.798 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.798 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.797 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.796 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.795 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.795 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.793 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.793 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.793 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.792 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.792 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.791 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.790 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.789 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.789 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.789 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.788 | |
| 4d04 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.787 | |
| 4jn9 | FAD | DepH | / | 0.787 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.786 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.785 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.785 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.784 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.784 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.783 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.782 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.781 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.779 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.779 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.778 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.778 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.778 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.777 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.777 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.775 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.775 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.775 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.773 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.773 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.773 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.773 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.773 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.772 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.772 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.771 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.770 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.770 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.770 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.770 | |
| 2rgj | FAD | Flavin-containing monooxygenase | / | 0.770 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.770 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.770 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.770 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.770 | |
| 4nte | FAD | DepH | / | 0.770 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.770 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.770 | |
| 4tlz | FAD | KtzI | / | 0.770 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.769 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.769 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.769 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.768 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.768 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.767 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.767 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.765 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.763 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.763 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.763 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.762 | |
| 4tm3 | FAD | KtzI | / | 0.762 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.761 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.760 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.760 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.760 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.759 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.759 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.759 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.759 | |
| 4usr | FAD | Monooxygenase | / | 0.759 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.758 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.758 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.758 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.758 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.758 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.757 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.756 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.756 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.756 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.755 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.755 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.755 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.755 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.755 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.755 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.755 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.755 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.755 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.755 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.754 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.753 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.752 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.751 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.751 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.749 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.748 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.748 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.748 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.748 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.747 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.747 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.747 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.747 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.745 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.745 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.745 | |
| 3rha | FDA | Putrescine oxidase | / | 0.745 | |
| 4txi | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.745 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.744 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.744 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.744 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.743 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.743 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.742 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.742 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.742 | |
| 4k5r | FAD | Oxygenase | / | 0.741 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.740 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.739 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.739 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.738 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.738 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.738 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.737 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.737 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.736 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.735 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.735 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.735 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.735 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.734 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.734 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.734 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.734 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.734 | |
| 3ihg | FAD | Aklavinone 12-hydroxylase RdmE | / | 0.733 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.731 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.731 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.730 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.730 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.729 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.728 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.727 | |
| 2cul | FAD | GidA-related protein | / | 0.726 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.726 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.725 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.725 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.725 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.725 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.724 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.724 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.724 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.724 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.724 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.724 | |
| 2bab | FAD | Putative aminooxidase | / | 0.723 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.723 | |
| 2yls | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.723 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.723 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.722 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.721 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.721 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.720 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.720 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.720 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.719 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.717 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.717 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.717 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.716 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.716 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.715 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.715 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.714 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.714 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.713 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.713 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.712 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.712 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.712 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.711 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.711 | |
| 2bac | FAD | Putative aminooxidase | / | 0.710 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.710 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.710 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.710 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.710 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.710 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.709 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.709 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.709 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.708 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.708 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 0.708 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.708 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.707 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.707 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.707 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.707 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.706 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.706 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.706 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.706 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.706 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.705 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.705 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.705 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.705 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.705 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.705 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.704 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.704 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.704 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.703 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.703 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.703 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.703 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.702 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.702 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.702 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.701 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.701 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.701 | |
| 4icy | FAD | PgaE | / | 0.701 | |
| 4tm1 | FDA | KtzI | / | 0.701 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.699 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.699 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.699 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.698 | |
| 2o06 | MTA | Spermidine synthase | 2.5.1.16 | 0.698 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.698 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.697 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.697 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.696 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.695 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.694 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.692 | |
| 2hmv | ADP | Ktr system potassium uptake protein A | / | 0.692 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.692 | |
| 5dwq | SFG | Histone-arginine methyltransferase CARM1 | / | 0.692 | |
| 5dxj | SFG | Histone-arginine methyltransferase CARM1 | / | 0.692 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.692 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.691 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.691 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.691 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.691 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.690 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.690 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.689 | |
| 5dxa | SFG | Histone-arginine methyltransferase CARM1 | / | 0.689 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.688 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.688 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.688 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.687 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.687 | |
| 3ute | FAD | UDP-galactopyranose mutase | / | 0.687 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.686 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.686 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.686 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.686 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.685 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.684 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.684 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.683 | |
| 3a26 | MTA | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.683 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.683 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.683 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.682 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.681 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.681 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.680 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.680 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.680 | |
| 4yv2 | S4M | Spermidine synthase, putative | / | 0.680 | |
| 1y56 | ATP | Uncharacterized protein | / | 0.679 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.679 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.679 | |
| 5je3 | SAH | Methyl transferase | / | 0.679 | |
| 3h5n | ATP | MccB protein | / | 0.678 | |
| 5jdz | SAH | Methyl transferase | / | 0.678 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.677 | |
| 2ore | SAH | DNA adenine methylase | 2.1.1.72 | 0.677 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.677 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.677 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.677 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.677 | |
| 4xr9 | NAD | CalS8 | / | 0.677 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.676 | |
| 2bzg | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.676 | |
| 3awi | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | 1.5 | 0.676 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.676 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.676 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.676 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.675 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.674 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.674 | |
| 3uj8 | SFG | Phosphoethanolamine N-methyltransferase | / | 0.674 | |
| 4mwz | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.674 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.674 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.673 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.673 | |
| 2y1x | SAH | Histone-arginine methyltransferase CARM1 | / | 0.673 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.673 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.672 | |
| 2cdu | ADP | NADH oxidase | / | 0.672 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.672 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.672 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.672 | |
| 3gry | SAM | Probable ribosomal RNA small subunit methyltransferase A | / | 0.672 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.672 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.671 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.671 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.671 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.671 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.671 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.671 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.670 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.670 | |
| 5bxy | SAH | Putative RNA methylase family UPF0020 | / | 0.670 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.669 | |
| 2uyh | SAH | Modification methylase HhaI | 2.1.1.37 | 0.669 | |
| 3cin | NAD | Myo-inositol-1-phosphate synthase-related protein | / | 0.669 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.669 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.669 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.668 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.668 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.668 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.668 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.667 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.666 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.666 | |
| 1onf | FAD | Glutathione reductase | 1.8.1.7 | 0.665 | |
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 | 0.665 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.665 | |
| 2plw | SAM | Ribosomal RNA methyltransferase, putative | / | 0.665 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.665 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.665 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.665 | |
| 4tm0 | FAD | KtzI | / | 0.665 | |
| 5dst | SAH | Protein arginine N-methyltransferase 8 | 2.1.1 | 0.665 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.664 | |
| 1sc6 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.664 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.664 | |
| 2okc | SAM | Probable type I restriction enzyme BthVORF4518P M protein | 2.1.1.72 | 0.664 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.664 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.664 | |
| 1sez | FAD | Protoporphyrinogen oxidase, mitochondrial | 1.3.3.4 | 0.663 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.663 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.663 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.662 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.662 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.662 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.662 | |
| 4c5o | FAD | Putative monooxygenase | / | 0.662 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.662 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.661 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.661 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.661 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.660 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.660 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.660 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.660 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.660 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.660 | |
| 1skm | SAH | Modification methylase HhaI | 2.1.1.37 | 0.659 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.659 | |
| 4xqc | NAD | Homospermidine synthase | 2.5.1.44 | 0.659 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.659 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.659 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.658 | |
| 2c7q | SAH | Modification methylase HhaI | 2.1.1.37 | 0.658 | |
| 3lcc | SAH | Thiocyanate methyltransferase 1 | / | 0.658 | |
| 4eqg | A5A | Histidine triad nucleotide-binding protein 1 | 3 | 0.658 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.658 | |
| 4qdk | SAH | Magnesium-protoporphyrin O-methyltransferase | 2.1.1.11 | 0.658 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.657 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.657 | |
| 4eqe | KAA | Histidine triad nucleotide-binding protein 1 | 3 | 0.657 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.657 | |
| 5hxw | FAD | L-amino acid deaminase | / | 0.657 | |
| 2yx1 | SFG | tRNA (guanine(37)-N1)-methyltransferase Trm5b | 2.1.1.228 | 0.656 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.656 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.656 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.656 | |
| 1geu | NAD | Glutathione reductase | 1.8.1.7 | 0.655 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.655 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.655 | |
| 1wg8 | SAM | Ribosomal RNA small subunit methyltransferase H | / | 0.654 | |
| 1x7d | NAD | Putative ornithine cyclodeaminase | / | 0.654 | |
| 2yxl | SFG | 450aa long hypothetical fmu protein | / | 0.654 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.654 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.653 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.653 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.653 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.652 | |
| 3abi | NAD | Uncharacterized protein | / | 0.652 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.652 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.652 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.652 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.652 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.652 | |
| 1yc2 | APR | NAD-dependent protein deacylase 2 | / | 0.651 | |
| 4fp9 | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.651 | |
| 4iv8 | SAM | Phosphoethanolamine N-methyltransferase,putative | / | 0.651 | |
| 5f8f | SFG | Possible transcriptional regulatory protein | / | 0.651 | |
| 2hnk | SAH | SAM-dependent O-methyltransferase | / | 0.650 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.650 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.650 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.650 |