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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5aaaVGHALK tyrosine kinase receptor2.7.10.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5aaaVGHALK tyrosine kinase receptor2.7.10.11.000
2yfxVGHALK tyrosine kinase receptor2.7.10.10.727
4anqVGHALK tyrosine kinase receptor2.7.10.10.677
5aacVGHALK tyrosine kinase receptor2.7.10.10.635
5aabVGHALK tyrosine kinase receptor2.7.10.10.633
4ansVGHALK tyrosine kinase receptor2.7.10.10.630
2xp2VGHALK tyrosine kinase receptor2.7.10.10.615
4cd0AWJALK tyrosine kinase receptor2.7.10.10.571
4ccbOFGALK tyrosine kinase receptor2.7.10.10.570
4fob0USALK tyrosine kinase receptor2.7.10.10.570
4gmy0X5Tyrosine-protein kinase JAK2/0.562
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.531
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.523
3vryB43Tyrosine-protein kinase HCK2.7.10.20.523
2pwlACPFibroblast growth factor receptor 2/0.522
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.521
4c62XWWTyrosine-protein kinase JAK2/0.521
2vwu7X1Ephrin type-B receptor 42.7.10.10.520
4nks2M2Fibroblast growth factor receptor 1/0.520
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.519
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.519
4nka2K7Fibroblast growth factor receptor 1/0.519
2itnANPEpidermal growth factor receptor2.7.10.10.513
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.512
3vjoANPEpidermal growth factor receptor2.7.10.10.510
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.510
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.509
4c61LMMTyrosine-protein kinase JAK2/0.509
4f630S7Fibroblast growth factor receptor 1/0.509
2j0m4STFocal adhesion kinase 12.7.10.20.508
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.507
4b99R4LMitogen-activated protein kinase 72.7.11.240.507
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.506
2c6eHPMAurora kinase A2.7.11.10.505
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.505
2xb7GUIALK tyrosine kinase receptor2.7.10.10.505
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.505
2qo9ANPEphrin type-A receptor 32.7.10.10.504
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.504
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.503
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.503
2xa4AZ5Tyrosine-protein kinase JAK2/0.501
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.501
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.501
4ccuAWFALK tyrosine kinase receptor2.7.10.10.500
4gk4L90Ephrin type-A receptor 32.7.10.10.500
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.499
2vgoAD5Aurora kinase B-A2.7.11.10.499
4id71G0Activated CDC42 kinase 1/0.499
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.498
1u54ACPActivated CDC42 kinase 1/0.498
2bfyH1NAurora kinase B-A2.7.11.10.498
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.498
2henADPEphrin type-B receptor 22.7.10.10.498
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.498
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.498
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.497
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.497
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.497
3zewSTUEphrin type-B receptor 42.7.10.10.496
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.496
4qmlANPSerine/threonine-protein kinase 242.7.11.10.496
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.495
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.495
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.495
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.495
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.495
5e8xSTUTGF-beta receptor type-12.7.11.300.495
2hk51BMTyrosine-protein kinase HCK2.7.10.20.494
2hog710Serine/threonine-protein kinase Chk12.7.11.10.494
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.493
3w2sW2REpidermal growth factor receptor2.7.10.10.493
4foc0UUALK tyrosine kinase receptor2.7.10.10.493
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.492
5e8ySTUTGF-beta receptor type-22.7.11.300.492
2py3ACPFibroblast growth factor receptor 2/0.491
3lctADPALK tyrosine kinase receptor2.7.10.10.491
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.491
4gk3L87Ephrin type-A receptor 32.7.10.10.491
2etm7PYFocal adhesion kinase 12.7.10.20.490
4f640S8Fibroblast growth factor receptor 1/0.490
4j97ACPFibroblast growth factor receptor 2/0.490
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.490
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.490
1ir3ANPInsulin receptor2.7.10.10.489
4y95746Tyrosine-protein kinase/0.489
2of4979Tyrosine-protein kinase Lck2.7.10.20.488
3a7hATPSerine/threonine-protein kinase 242.7.11.10.488
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.488
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.487
2ittAEEEpidermal growth factor receptor2.7.10.10.487
2itzIREEpidermal growth factor receptor2.7.10.10.487
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.487
3vjnANPEpidermal growth factor receptor2.7.10.10.487
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.487
2wqeADPAurora kinase A2.7.11.10.486
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.486
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.486
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.486
4i22IREEpidermal growth factor receptor2.7.10.10.486
4riyADPEpidermal growth factor receptor2.7.10.10.486
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.485
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.485
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.485
4bcmT7ZCyclin-dependent kinase 22.7.11.220.485
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.484
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.484
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.484
4fod0UVALK tyrosine kinase receptor2.7.10.10.484
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.484
4wkqIREEpidermal growth factor receptor2.7.10.10.484
2j0lANPFocal adhesion kinase 12.7.10.20.483
2v7a627Tyrosine-protein kinase ABL12.7.10.20.483
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.483
3t8oATPRhodopsin kinase/0.483
4jia1K3Tyrosine-protein kinase JAK2/0.483
2itqITQEpidermal growth factor receptor2.7.10.10.482
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.482
4nk92K5Fibroblast growth factor receptor 1/0.482
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.482
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.482
1bygSTUTyrosine-protein kinase CSK/0.481
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.481
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.481
4b8lA0PAurora kinase B-A2.7.11.10.481
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.481
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.481
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.480
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.480
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.480
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
2j0j4STFocal adhesion kinase 12.7.10.20.479
2pz5ACPFibroblast growth factor receptor 2/0.479
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.479
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
1i44ACPInsulin receptor2.7.10.10.478
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.478
2xru400Aurora kinase A2.7.11.10.478
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.478
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.478
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.478
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.478
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.478
4y93746Tyrosine-protein kinase/0.478
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.477
3pxkPXKFocal adhesion kinase 12.7.10.20.477
4erwSTUCyclin-dependent kinase 22.7.11.220.477
1mqbANPEphrin type-A receptor 22.7.10.10.476
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.476
1xjdSTUProtein kinase C theta type2.7.11.130.476
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.476
2qoqANPEphrin type-A receptor 32.7.10.10.476
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.476
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.476
4gk2L66Ephrin type-A receptor 32.7.10.10.476
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.476
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.475
2pzpACPFibroblast growth factor receptor 2/0.475
3gubGUBDeath-associated protein kinase 12.7.11.10.475
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.475
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.475
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.474
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.474
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.474
4gu94GUFocal adhesion kinase 12.7.10.20.474
4i231C9Epidermal growth factor receptor2.7.10.10.474
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
2i40BLZCyclin-dependent kinase 22.7.11.220.473
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.473
3w33W19Epidermal growth factor receptor2.7.10.10.473
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.473
4dce0JFALK tyrosine kinase receptor2.7.10.10.473
2wipP49Cyclin-dependent kinase 22.7.11.220.472
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.472
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.472
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.472
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.472
2x1nX1NCyclin-dependent kinase 22.7.11.220.471
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.471
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.471
4hvh19RTyrosine-protein kinase JAK32.7.10.20.471
2vd5BI8Myotonin-protein kinase2.7.11.10.470
2vrx447Aurora kinase B-A2.7.11.10.470
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.470
4k8aK8AFocal adhesion kinase 12.7.10.20.470
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.469
3ormAGSSerine/threonine protein kinase/0.469
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.469
3uvqFS8Mitogen-activated protein kinase 14/0.469
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.469
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.469
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.468
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.468
3qtsX46Cyclin-dependent kinase 22.7.11.220.468
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.468
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.468
1oecAA2Fibroblast growth factor receptor 2/0.467
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.467
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.467
2yn8STUEphrin type-B receptor 42.7.10.10.467
3a62STURibosomal protein S6 kinase beta-12.7.11.10.467
3r73X87Cyclin-dependent kinase 22.7.11.220.467
3s2pPMUCyclin-dependent kinase 22.7.11.220.467
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.467
2itpAEEEpidermal growth factor receptor2.7.10.10.466
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.466
2y6o1N1Ephrin type-A receptor 42.7.10.10.466
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.466
4c3pACPAurora kinase A2.7.11.10.466
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.466
4jrvKJVEpidermal growth factor receptor2.7.10.10.466
4nj32KDCyclin-dependent kinase 22.7.11.220.466
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.466
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.465
2c4g514Cyclin-dependent kinase 22.7.11.220.465
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.465
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
3ttjJBIMitogen-activated protein kinase 102.7.11.240.465
4eym0RXMitogen-activated protein kinase 132.7.11.240.465
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.465
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.464
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.464
2x6dX6DAurora kinase A2.7.11.10.464
3emg685Tyrosine-protein kinase SYK2.7.10.20.464
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
3r7uX96Cyclin-dependent kinase 22.7.11.220.464
4deaNHIAurora kinase A2.7.11.10.464
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.464
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.464
5auwQUEDeath-associated protein kinase 12.7.11.10.464
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.464
1finATPCyclin-dependent kinase 22.7.11.220.463
1oguST8Cyclin-dependent kinase 22.7.11.220.463
1oiyN41Cyclin-dependent kinase 22.7.11.220.463
2ijmADPFocal adhesion kinase 12.7.10.20.463
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.463
2vgpAD6Aurora kinase B-A2.7.11.10.463
2vx17X8Ephrin type-B receptor 42.7.10.10.463
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.463
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.463
4bb432WEphrin type-B receptor 42.7.10.10.463
4ic7ANPMitogen-activated protein kinase 72.7.11.240.463
1jpaANPEphrin type-B receptor 22.7.10.10.462
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.462
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.462
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.462
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.462
3l8p0CEAngiopoietin-1 receptor2.7.10.10.462
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.462
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.462
4k33ACPFibroblast growth factor receptor 32.7.10.10.462
2qo7ANPEphrin type-A receptor 32.7.10.10.461
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.461
3q5iANPProtein kinase, putative/0.461
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.461
2x9fX9FEphrin type-B receptor 42.7.10.10.460
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.460
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3k5uPFQAurora kinase A2.7.11.10.460
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.460
5dr9SKEAurora kinase A2.7.11.10.460
2c5nCK8Cyclin-dependent kinase 22.7.11.220.459
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.459
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.459
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.459
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.459
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.459
4f650S9Fibroblast growth factor receptor 1/0.459
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.459
4hvg19QTyrosine-protein kinase JAK32.7.10.20.459
4hyu1BKMitogen-activated protein kinase 82.7.11.240.459
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.459
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.458
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.458
2j0k4STFocal adhesion kinase 12.7.10.20.458
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.458
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.458
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.458
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3lpbNVBTyrosine-protein kinase JAK2/0.458
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.458
3rm719ZCyclin-dependent kinase 22.7.11.220.458
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.458
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.458
4g2fC07Ephrin type-A receptor 32.7.10.10.458
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
1rw8580TGF-beta receptor type-12.7.11.300.457
2itvANPEpidermal growth factor receptor2.7.10.10.457
3iok1P6Tyrosine-protein kinase JAK2/0.457
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.457
3sheI85MAP kinase-activated protein kinase 32.7.11.10.457
4aotGW8Serine/threonine-protein kinase 102.7.11.10.457
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.457
4e730NRMitogen-activated protein kinase 82.7.11.240.457
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.457
1pkdUCNCyclin-dependent kinase 22.7.11.220.456
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.456
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.456
2pvyACPFibroblast growth factor receptor 2/0.456
2vwx7X4Ephrin type-B receptor 42.7.10.10.456
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.456
3b2tM33Fibroblast growth factor receptor 2/0.456
3fz1B98Cyclin-dependent kinase 22.7.11.220.456
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.456
3qwkX62Cyclin-dependent kinase 22.7.11.220.456
3w16P9JAurora kinase A2.7.11.10.456
4i4e1BQFocal adhesion kinase 12.7.10.20.456
4j95ACPFibroblast growth factor receptor 2/0.456
4l9i8PRRhodopsin kinase/0.456
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.455
2fgiPD1Fibroblast growth factor receptor 1/0.455
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.455
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.455
3r7eX88Cyclin-dependent kinase 22.7.11.220.455
4fuxE75Mitogen-activated protein kinase 12.7.11.240.455
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.455
1di8DTQCyclin-dependent kinase 22.7.11.220.454
1gih1PUCyclin-dependent kinase 22.7.11.220.454
1oi9N20Cyclin-dependent kinase 22.7.11.220.454
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.454
2xngA0HAurora kinase A2.7.11.10.454
3lfsA07Cyclin-dependent kinase 22.7.11.220.454
3tnwF18Cyclin-dependent kinase 22.7.11.220.454
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.454
4fnzNZFALK tyrosine kinase receptor2.7.10.10.454
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.454
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.454
1cm8ANPMitogen-activated protein kinase 12/0.453
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.453
2of2547Tyrosine-protein kinase Lck2.7.10.20.453
3ac1KZITyrosine-protein kinase Lck2.7.10.20.453
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.453
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.453
3rvg17PTyrosine-protein kinase JAK2/0.453
4eok4SPCyclin-dependent kinase 22.7.11.220.453
4jbqVX6Aurora kinase A2.7.11.10.453
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.453
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.452
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.452
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
3qqfX07Cyclin-dependent kinase 22.7.11.220.452
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.452
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.452
4erkOLOMitogen-activated protein kinase 12.7.11.240.452
4izy1J2Mitogen-activated protein kinase 82.7.11.240.452
4o0uADNAurora kinase A2.7.11.10.452
5dr6SKEAurora kinase A2.7.11.10.452
1e9hINRCyclin-dependent kinase 22.7.11.220.451
1g5sI17Cyclin-dependent kinase 22.7.11.220.451
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.451
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.451
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3r1qX75Cyclin-dependent kinase 22.7.11.220.451
3r1yX76Cyclin-dependent kinase 22.7.11.220.451
3r7vZ02Cyclin-dependent kinase 22.7.11.220.451
3vs1VSATyrosine-protein kinase HCK2.7.10.20.451
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.451
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.451
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.451
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.451
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.450
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.450
2w1fL0FAurora kinase A2.7.11.10.450
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.450
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.450
3vquO22Dual specificity protein kinase TTK2.7.12.10.450
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.450
1gy3ATPCyclin-dependent kinase 22.7.11.220.449
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.449
2bujSTUSerine/threonine-protein kinase 16/0.449
2c6dANPAurora kinase A2.7.11.10.449
2wotZZGTGF-beta receptor type-12.7.11.300.449
3a60STURibosomal protein S6 kinase beta-12.7.11.10.449
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4b8mVX6Aurora kinase B-A2.7.11.10.449
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.449
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4lopSB4Mitogen-activated protein kinase 14/0.449
4yuqKS1Calmodulin-like domain protein kinase/0.449
1agwSU2Fibroblast growth factor receptor 1/0.448
2itwITQEpidermal growth factor receptor2.7.10.10.448
2w1eL0EAurora kinase A2.7.11.10.448
2w1hL0FCyclin-dependent kinase 22.7.11.220.448
3ezrEZRCyclin-dependent kinase 22.7.11.220.448
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.448
4c02TAKActivin receptor type-12.7.11.300.448
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.448
5e8wSTUTGF-beta receptor type-12.7.11.300.448
1h0w207Cyclin-dependent kinase 22.7.11.220.447
1ke6LS2Cyclin-dependent kinase 22.7.11.220.447
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
1xkkFMMEpidermal growth factor receptor2.7.10.10.447
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.447
2uzlC94Cyclin-dependent kinase 22.7.11.220.447
3c4xATPRhodopsin kinase/0.447
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.447
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.447
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.447
4aqc88ATyrosine-protein kinase JAK2/0.447
4bcqTJFCyclin-dependent kinase 22.7.11.220.447
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.447
4e4m0NHTyrosine-protein kinase JAK2/0.447
1vyzN5BCyclin-dependent kinase 22.7.11.220.446
2eb3ANPEpidermal growth factor receptor2.7.10.10.446
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.446
2vww7X2Ephrin type-B receptor 42.7.10.10.446
3ggfGVDSerine/threonine-protein kinase 26/0.446
3qqkX02Cyclin-dependent kinase 22.7.11.220.446
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4hjoAQ4Epidermal growth factor receptor2.7.10.10.446
3r9nZ68Cyclin-dependent kinase 22.7.11.220.445
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.445
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.445
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.445
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.445
4qnaX11Serine/threonine-protein kinase 242.7.11.10.445
4wboANWRhodopsin kinase/0.445
1w0xOLOCyclin-dependent kinase 22.7.11.220.444
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.444
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4acm7YGCyclin-dependent kinase 22.7.11.220.444
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.443
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.443
2xneASHAurora kinase A2.7.11.10.443
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.443
3qxpX64Cyclin-dependent kinase 22.7.11.220.443
3s4qNK0Mitogen-activated protein kinase 14/0.443
3uo50BXAurora kinase A2.7.11.10.443
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.443
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.443
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.443
4g1wG1WMitogen-activated protein kinase 82.7.11.240.443
4jqeANPCasein kinase II subunit alpha2.7.11.10.443
4qo9627Serine/threonine-protein kinase 242.7.11.10.443
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.443
2cchATPCyclin-dependent kinase 22.7.11.220.442
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.442
2xrwANPMitogen-activated protein kinase 82.7.11.240.442
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.442
4eomATPCyclin-dependent kinase 22.7.11.220.442
4eos1ROCyclin-dependent kinase 22.7.11.220.442
4fki09KCyclin-dependent kinase 22.7.11.220.442
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.442
1h1r6CPCyclin-dependent kinase 22.7.11.220.441
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1wvxBD4Death-associated protein kinase 12.7.11.10.441
2iw94SPCyclin-dependent kinase 22.7.11.220.441
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.441
2vwy7X5Ephrin type-B receptor 42.7.10.10.441
2wouZZFTGF-beta receptor type-12.7.11.300.441
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.441
4bbe3O4Tyrosine-protein kinase JAK2/0.441
4c57FEFCyclin-G-associated kinase2.7.11.10.441
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.441
4jboWPHAurora kinase A2.7.11.10.441
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.441
4zseANPEpidermal growth factor receptor2.7.10.10.441
1h1s4SPCyclin-dependent kinase 22.7.11.220.440
1mp8ADPFocal adhesion kinase 12.7.10.20.440
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.440
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.440
2j50627Aurora kinase A2.7.11.10.440
2uzoC62Cyclin-dependent kinase 22.7.11.220.440
2w05FRTCyclin-dependent kinase 22.7.11.220.440
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.440
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3ddpRC8Cyclin-dependent kinase 22.7.11.220.440
3gxlQIGTGF-beta receptor type-12.7.11.300.440
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.440
4b0gVEKAurora kinase A2.7.11.10.440
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.440
4fyn0VETyrosine-protein kinase SYK2.7.10.20.440
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.440