Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ju7 | 1O6 | Genome polyprotein | 2.7.7.48 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ju6 | 1O6 | Genome polyprotein | 2.7.7.48 | 1.000 | |
| 4ju7 | 1O6 | Genome polyprotein | 2.7.7.48 | 1.000 | |
| 4jtz | 1NW | Genome polyprotein | 2.7.7.48 | 0.766 | |
| 4ju3 | 1O1 | Genome polyprotein | 2.7.7.48 | 0.639 | |
| 2hwh | RNA | Genome polyprotein | 2.7.7.48 | 0.626 | |
| 4eo8 | 0S3 | Genome polyprotein | 2.7.7.48 | 0.604 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.514 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.507 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.503 | |
| 4ju4 | 1O3 | Genome polyprotein | 2.7.7.48 | 0.502 | |
| 3bzu | A21 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.499 | |
| 1osv | CHC | Bile acid receptor | / | 0.498 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.495 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.494 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.494 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.492 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.490 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.489 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.489 | |
| 3cx5 | SMA | Cytochrome b | / | 0.488 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.487 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.487 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.486 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.486 | |
| 3cxh | SMA | Cytochrome b | / | 0.485 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.485 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.483 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.483 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.482 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.481 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.480 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.480 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.480 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.479 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 4ase | AV9 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.477 | |
| 1ezv | SMA | Cytochrome b | / | 0.476 | |
| 1sn5 | T3 | Transthyretin | / | 0.476 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.476 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.476 | |
| 2xir | 00J | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.476 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.476 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.476 | |
| 2bx8 | AZQ | Serum albumin | / | 0.475 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.475 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.474 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.474 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.474 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.473 | |
| 4nka | 2K7 | Fibroblast growth factor receptor 1 | / | 0.473 | |
| 4pds | ANP | Serine/threonine-protein kinase RAD53 | 2.7.12.1 | 0.473 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.473 | |
| 2rgh | FAD | Alpha-Glycerophosphate Oxidase | / | 0.472 | |
| 3dtw | A96 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.472 | |
| 3vhk | BPK | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.472 | |
| 4pd6 | URI | Nucleoside permease | / | 0.472 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.471 | |
| 2yiu | SMA | Cytochrome b | / | 0.471 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.471 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.471 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.471 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 4iwc | 1GV | Estrogen receptor | / | 0.471 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.471 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.470 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 3bej | MUF | Bile acid receptor | / | 0.470 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.470 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.470 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 1ppj | SMA | Cytochrome b | / | 0.469 | |
| 1sqv | UHD | Cytochrome b | / | 0.469 | |
| 2np9 | YE1 | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase | / | 0.469 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.469 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.469 | |
| 1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.468 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.468 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.468 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.468 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.468 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.468 | |
| 4l4x | NDP | AmphI | / | 0.468 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.467 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.467 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.467 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.467 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.466 | |
| 2ibz | SMA | Cytochrome b | / | 0.466 | |
| 3gco | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.466 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.466 | |
| 4b1f | KRH | Glutamate racemase | / | 0.466 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.466 | |
| 4l9z | COA | L-malyl-CoA/beta-methylmalyl-CoA lyase | 4.1.3.24 | 0.466 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 1hnd | COA | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.465 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.465 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.465 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.465 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.465 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.465 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.465 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.465 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.464 | |
| 1ie4 | T44 | Transthyretin | / | 0.464 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.464 | |
| 3vid | 4TT | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.464 | |
| 3w2c | N15 | Aurora kinase A | 2.7.11.1 | 0.464 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.464 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.464 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.463 | |
| 3k14 | 535 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.463 | |
| 3l70 | JZV | Cytochrome b | / | 0.463 | |
| 3mec | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 3stx | BKA | Methylketone synthase I | / | 0.463 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.463 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.463 | |
| 1kb9 | SMA | Cytochrome b | / | 0.462 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.462 | |
| 1qvn | FRI | Interleukin-2 | / | 0.462 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.462 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.462 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.462 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.462 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.462 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.462 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.462 | |
| 5aut | 2AN | Death-associated protein kinase 1 | 2.7.11.1 | 0.462 | |
| 1bh5 | GTX | Lactoylglutathione lyase | 4.4.1.5 | 0.461 | |
| 1hk4 | T44 | Serum albumin | / | 0.461 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.461 | |
| 1rc1 | KT3 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.461 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.461 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.461 | |
| 2pin | 4HY | Thyroid hormone receptor beta | / | 0.461 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.461 | |
| 3med | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 3mf5 | HJZ | Genome polyprotein | 2.7.7.48 | 0.461 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.461 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.461 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.460 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.460 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.460 | |
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.460 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.460 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.460 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.460 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.460 | |
| 5ap5 | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.460 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.459 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.459 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.459 | |
| 3ics | COA | Coenzyme A disulfide reductase | / | 0.459 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.459 | |
| 4aa0 | AA0 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 4eny | J19 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.459 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.458 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.458 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.458 | |
| 1uyr | D1L | Acetyl-CoA carboxylase | / | 0.458 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.458 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3h1j | SMA | Cytochrome b | / | 0.458 | |
| 3ln0 | 52B | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.458 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.458 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.458 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.458 | |
| 3wxy | COA | Uncharacterized protein | / | 0.458 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4bi1 | ZO6 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.458 | |
| 4lgh | 0JN | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.458 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.458 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.457 | |
| 1fbm | RTL | Cartilage oligomeric matrix protein | / | 0.457 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.457 | |
| 2vg5 | NNC | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.457 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.457 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.457 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.457 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.457 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.456 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.456 | |
| 2hzi | JIN | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.456 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.456 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.456 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3dl9 | BCD | Vitamin D 25-hydroxylase | / | 0.456 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.456 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.456 | |
| 3qai | XNN | Ketohexokinase | / | 0.456 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4ez7 | 2AN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4hee | 14R | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 4mzu | COA | WxcM-like protein | / | 0.456 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.455 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.455 | |
| 2y03 | Y01 | Beta-1 adrenergic receptor | / | 0.455 | |
| 2zmd | 537 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.455 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.455 | |
| 3hng | 8ST | Vascular endothelial growth factor receptor 1 | 2.7.10.1 | 0.455 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.455 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.455 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.455 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.455 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.454 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.454 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1pp9 | SMA | Cytochrome b | / | 0.454 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 3efl | 706 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.454 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.454 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.454 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.454 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.454 | |
| 3zxt | ACP | Death-associated protein kinase 1 | 2.7.11.1 | 0.454 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.454 | |
| 4c8b | 0LI | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.454 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.454 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.454 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.454 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.454 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.453 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.453 | |
| 1rc0 | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.453 | |
| 1u30 | GOX | Pancreatic alpha-amylase | / | 0.453 | |
| 1u3w | FXY | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.453 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.453 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.453 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.453 | |
| 2j7t | 274 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.453 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.453 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.453 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.453 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.453 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.453 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.453 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.453 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.453 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.453 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.453 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.453 | |
| 4inb | 1F6 | Gag protein | / | 0.453 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.453 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.452 | |
| 2p2i | 608 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.452 | |
| 3h65 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.452 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.452 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.452 | |
| 3roc | 29A | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.452 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4eqc | XR1 | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.452 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.452 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.452 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.452 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.452 | |
| 5a3b | APR | SIR2 family protein | / | 0.452 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.451 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.451 | |
| 1kyo | SMA | Cytochrome b | / | 0.451 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.451 | |
| 1tz8 | DES | Transthyretin | / | 0.451 | |
| 1xkk | FMM | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 2c6o | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.451 | |
| 2w7x | D1A | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.451 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.451 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.451 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.451 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.451 | |
| 3w18 | N13 | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 4cjw | CBJ | Integrase | / | 0.451 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.451 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.451 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.451 | |
| 4wq5 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.451 | |
| 4wuj | FMN | Glycoside hydrolase family 15, cellulose signaling associated protein envoy | / | 0.451 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.451 | |
| 1bve | DMP | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.450 | |
| 1qnf | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.450 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.450 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.450 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.450 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 2acw | UPG | Glycosyltransferase | / | 0.450 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 2gtm | LID | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.450 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3amb | VX6 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.450 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.450 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.450 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.450 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.450 | |
| 3wec | AUI | Cytochrome P450 | / | 0.450 | |
| 3zln | H0Y | Bcl-2-like protein 1 | / | 0.450 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.450 | |
| 4fic | 0UL | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.450 | |
| 4jap | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.450 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.450 | |
| 5kcp | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1hnj | MLC | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.449 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.449 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.449 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.449 | |
| 1zyj | BI5 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2qe6 | SAM | Uncharacterized protein | / | 0.449 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.449 | |
| 3anp | DCC | Transcriptional repressor, TetR family | / | 0.449 | |
| 3cp9 | C19 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.449 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.449 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3ha8 | 5JZ | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3nf7 | CIW | Gag-Pol polyprotein | / | 0.449 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.449 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.449 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.449 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.449 | |
| 4bc6 | XZN | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.449 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.449 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.449 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.449 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.449 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.448 | |
| 1tll | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.448 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.448 | |
| 2qjy | SMA | Cytochrome b | / | 0.448 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.448 | |
| 2ycs | NXP | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 2yit | YIT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.448 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.448 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.448 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.448 | |
| 3p7b | P7B | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.448 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 4jkt | 04A | Glutaminase kidney isoform, mitochondrial | 3.5.1.2 | 0.448 | |
| 4lb2 | DM5 | Serum albumin | / | 0.448 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 4ot2 | NPS | Serum albumin | / | 0.448 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.448 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.448 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.447 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1fnn | ADP | ORC1-type DNA replication protein | / | 0.447 | |
| 1ht8 | 34C | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.447 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.447 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.447 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.447 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2k5t | COA | PanD regulatory factor | / | 0.447 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2oyu | IMS | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.447 | |
| 2w1h | L0F | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2ydf | IO3 | Serum albumin | / | 0.447 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.447 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.447 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.447 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.447 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 3m8p | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.447 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.447 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.447 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.447 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.447 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.447 | |
| 4ylh | YE1 | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase | / | 0.447 | |
| 4zbr | NPS | Serum albumin | / | 0.447 | |
| 5c7h | NDP | Putative oxidoreductase | / | 0.447 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.447 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1hk5 | T44 | Serum albumin | / | 0.446 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.446 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2jjx | ATP | Uridylate kinase | / | 0.446 | |
| 2uw5 | GVN | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.446 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.446 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 3r35 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.446 | |
| 3sh0 | SAX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.446 | |
| 3w3d | ATP | Actin, gamma-enteric smooth muscle | / | 0.446 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.446 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.446 | |
| 5av3 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.446 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1ict | T44 | Transthyretin | / | 0.445 | |
| 1kt4 | RTL | Retinol-binding protein 4 | / | 0.445 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.445 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.445 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.445 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.445 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.445 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.445 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2giu | FBR | Estrogen receptor beta | / | 0.445 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.445 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.445 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.445 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.445 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta | / | 0.445 | |
| 3eql | MXP | DNA-directed RNA polymerase subunit beta' | / | 0.445 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.445 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 4bdi | HAU | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.445 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.445 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.445 | |
| 4hys | 1BJ | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.445 | |
| 4i3w | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.445 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.445 | |
| 4mcv | 29K | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.444 | |
| 1eqh | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.444 | |
| 1kgj | FL8 | Transthyretin | / | 0.444 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1xdk | REA | Retinoic acid receptor beta | / | 0.444 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.444 | |
| 2c47 | 5ID | Casein kinase I isoform gamma-2 | / | 0.444 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2rr1 | W8R | Genome polyprotein | / | 0.444 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.444 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.444 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.444 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.444 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.444 | |
| 3l8x | N4D | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3mpa | SB2 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3p7c | P7C | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.444 | |
| 3up3 | XCA | aceDAF-12 | / | 0.444 | |
| 3zcw | 4A2 | Kinesin-like protein KIF11 | / | 0.444 | |
| 3zux | TCH | Transporter | / | 0.444 | |
| 4c4g | 7RO | Dual specificity protein kinase TTK | 2.7.12.1 | 0.444 | |
| 4emy | PLP | Aminotransferase class I and II | / | 0.444 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.444 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.444 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.444 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 6gsx | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.444 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.443 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.443 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.443 | |
| 1s1p | NAP | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.443 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.443 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.443 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.443 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.443 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.443 | |
| 3o8u | BMU | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.443 | |
| 3q92 | XNB | Ketohexokinase | / | 0.443 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 4aos | NAP | Steroid monooxygenase | / | 0.443 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.443 | |
| 4c3s | NAD | Aldehyde Dehydrogenase | / | 0.443 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.443 | |
| 4l9q | 9TP | Serum albumin | / | 0.443 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.443 | |
| 5l7d | CLR | Smoothened homolog | / | 0.443 | |
| 1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.442 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.442 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.442 | |
| 1ikw | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1nde | MON | Estrogen receptor beta | / | 0.442 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1o1v | TCH | Gastrotropin | / | 0.442 | |
| 1ori | SAH | Protein arginine N-methyltransferase 1 | / | 0.442 | |
| 1ppj | ANY | Cytochrome b | / | 0.442 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.442 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2gej | GDD | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.442 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.442 | |
| 2ycq | UPX | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.442 | |
| 2yfx | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.442 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.442 | |
| 3eel | 53T | Uncharacterized protein | / | 0.442 | |
| 3fr0 | AJB | Glucokinase | 2.7.1.2 | 0.442 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.442 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.442 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.442 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.442 | |
| 3tgu | WF3 | Cytochrome b | / | 0.442 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.442 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.442 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4jld | ADP | Adenylate kinase | / | 0.442 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4ksp | 1SU | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.442 | |
| 4mxa | BK7 | Calmodulin-like domain protein kinase isoenzyme gamma, related | / | 0.442 | |
| 4pyt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.442 | |
| 4s34 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.442 | |
| 5hi2 | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.442 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.441 | |
| 1fd0 | 254 | Retinoic acid receptor gamma | / | 0.441 | |
| 1fk9 | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.441 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 1uog | P1C | Deacetoxycephalosporin C synthase | 1.14.20.1 | 0.441 | |
| 1v5e | FAD | Pyruvate oxidase | / | 0.441 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 1zdw | FLV | Prenyltransferase | / | 0.441 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2jd1 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.441 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.441 | |
| 3aba | FLI | Cytochrome P450 | / | 0.441 | |
| 3eem | 53V | Uncharacterized protein | / | 0.441 | |
| 3fi4 | FI4 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.441 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.441 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.441 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.441 | |
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.441 | |
| 3vqu | O22 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 3wd7 | COA | Acridone synthase | / | 0.441 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.441 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4ekk | ANP | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.441 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.441 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.441 | |
| 4q5h | ANP | Protein kinase OspG | 2.7 | 0.441 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.441 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.441 | |
| 1cde | DZF | Phosphoribosylglycinamide formyltransferase | / | 0.440 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.440 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1kv2 | B96 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.440 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.440 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 2etm | 7PY | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.440 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.440 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.440 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.440 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 2wqe | ADP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.440 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.440 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 3gb4 | D3M | DdmC | / | 0.440 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 3nbw | TR4 | Ketohexokinase | / | 0.440 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3qa2 | XNA | Ketohexokinase | / | 0.440 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.440 | |
| 3qyw | 6PB | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 3ruq | ADP | Chaperonin | / | 0.440 | |
| 3t8o | ATP | Rhodopsin kinase | / | 0.440 | |
| 3tzl | ADP | Tryptophan--tRNA ligase | / | 0.440 | |
| 4at9 | UTP | Interleukin enhancer-binding factor 2 | / | 0.440 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.440 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4kd1 | 1QK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.440 | |
| 4nxu | ADP | Mitochondrial dynamics protein MID51 | / | 0.440 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.440 | |
| 4rrw | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 4rrz | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 5dr9 | SKE | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.440 |