sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 1.000 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.647 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.630 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.619 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.613 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.612 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.605 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.602 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.600 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.596 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.595 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.594 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.594 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.591 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.589 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.587 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.587 | |
| 2fyp | RDE | Endoplasmin | / | 0.586 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.580 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.580 | |
| 3ied | AN2 | HSP90 | / | 0.578 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.578 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.577 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.573 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.573 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.572 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.568 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.567 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.566 | |
| 2o1u | ANP | Endoplasmin | / | 0.565 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.565 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.561 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.560 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.560 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.559 | |
| 2exl | GDM | Endoplasmin | / | 0.558 | |
| 1yt0 | ADP | Endoplasmin | / | 0.557 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.556 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.553 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.552 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.550 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.550 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.549 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.549 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.548 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.548 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.547 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.545 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.544 | |
| 1u2o | NEC | Endoplasmin | / | 0.542 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.541 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.541 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.541 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.538 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.536 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 2esa | GDM | Endoplasmin | / | 0.532 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.532 | |
| 2o1v | ADP | Endoplasmin | / | 0.531 | |
| 2vwc | BC2 | ATP-dependent molecular chaperone HSP82 | / | 0.531 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.531 | |
| 1u0z | RDC | Endoplasmin | / | 0.530 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 2gqp | PA7 | Endoplasmin | / | 0.528 | |
| 2hg1 | N5O | Endoplasmin | / | 0.528 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 1qy8 | RDI | Endoplasmin | / | 0.527 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.527 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.525 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.524 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.524 | |
| 2hch | N5A | Endoplasmin | / | 0.523 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.522 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.519 | |
| 3q5l | KX2 | Heat shock protein 83-1 | / | 0.519 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 2gfd | RDA | Endoplasmin | / | 0.517 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.517 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.515 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 1qy5 | NEC | Endoplasmin | / | 0.510 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.508 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.508 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 1ysz | NEC | Endoplasmin | / | 0.507 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.507 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.505 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.504 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.503 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.500 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.495 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.494 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.494 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.492 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.492 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.491 | |
| 1u0y | PA7 | Endoplasmin | / | 0.491 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.490 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.490 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.489 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.489 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.487 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.486 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.486 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.486 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 2ye4 | 2FY | Heat shock protein HSP 90-alpha | / | 0.485 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.483 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.483 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.482 | |
| 1i58 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.481 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.480 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.480 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.479 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.478 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.478 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.476 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.475 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.474 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.474 | |
| 2wi1 | ZZ2 | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 2yec | XQ0 | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.473 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.473 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.472 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.472 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.471 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.471 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.470 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.470 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.469 | |
| 2bu2 | ATP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.469 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.468 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.467 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.466 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.465 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.465 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.465 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.463 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.463 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.462 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 2zdx | P4A | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.462 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.462 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.462 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.461 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4lb2 | DM5 | Serum albumin | / | 0.460 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.459 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.459 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.459 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3rr3 | FLR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.459 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.459 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.458 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.457 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1ol6 | ATP | Aurora kinase A | 2.7.11.1 | 0.456 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 4e93 | GUI | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.456 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.456 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.455 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.455 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.454 | |
| 3eof | FMN | Putative oxidase | / | 0.454 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.454 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.454 | |
| 4jvr | 1MT | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2z7l | S91 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.453 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.453 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.453 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.453 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.452 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.452 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.452 | |
| 4fl2 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.452 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.451 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.451 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.451 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.450 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.450 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.449 | |
| 1nxk | STU | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.449 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.449 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.449 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.448 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.448 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.448 | |
| 4ic7 | ANP | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.448 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.448 | |
| 4ok1 | 198 | Androgen receptor | / | 0.448 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.447 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.447 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.447 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.446 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.446 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.446 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 2rio | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.446 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 2yi6 | 6QM | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 1yin | CM3 | Estrogen receptor | / | 0.445 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2v1a | FMN | NPH1-1 | / | 0.445 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.445 | |
| 4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.445 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.445 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.445 | |
| 1am4 | GNP | Cell division control protein 42 homolog | / | 0.444 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.444 | |
| 1h7u | AGS | Mismatch repair endonuclease PMS2 | 3.1 | 0.444 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2izs | BRQ | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.444 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.444 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.444 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.444 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.444 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.444 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2np8 | CC3 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.443 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.443 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1ir3 | ANP | Insulin receptor | 2.7.10.1 | 0.442 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.442 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.442 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.442 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.442 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.442 | |
| 3eej | 53R | Uncharacterized protein | / | 0.442 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.442 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.442 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.441 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.441 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.441 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.441 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.441 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.440 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.440 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.440 | |
| 2hkj | RDC | Type 2 DNA topoisomerase 6 subunit B | / | 0.440 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4cvl | ACP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.440 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.440 | |
| 4fcq | 2N6 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.440 | |
| 4jhz | 1KV | Beta-glucuronidase | 3.2.1.31 | 0.440 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 |