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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2d32ANPGlutamate--cysteine ligase6.3.2.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2d32ANPGlutamate--cysteine ligase6.3.2.21.000
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.516
2fjbSFDAdenylylsulfate reductase, subunit A (AprA)/0.501
1rzuADPGlycogen synthase 12.4.1.210.500
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.496
3d7zGK5Mitogen-activated protein kinase 14/0.495
1dliUDXUDP-glucose 6-dehydrogenase/0.492
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.492
4jauADPSensor histidine kinase/0.487
1nhkCMPNucleoside diphosphate kinase2.7.4.60.484
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.484
3h3qH13Collagen type IV alpha-3-binding protein/0.484
4twnB96Ephrin type-A receptor 32.7.10.10.484
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.483
4aa5NQBMitogen-activated protein kinase 14/0.481
4pleCPSNuclear receptor subfamily 5 group A member 2/0.479
1rw8580TGF-beta receptor type-12.7.11.300.478
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.477
2a9y26AAdenosine kinase2.7.1.200.476
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.476
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.476
2gfsPQBMitogen-activated protein kinase 14/0.475
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.474
4dptAGSMevalonate diphosphate decarboxylase/0.474
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.474
2bt4CA23-dehydroquinate dehydratase4.2.1.100.473
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.473
1z6tADPApoptotic protease-activating factor 1/0.472
2po7CHDFerrochelatase, mitochondrial4.99.1.10.471
2vmyFFOSerine hydroxymethyltransferase/0.471
3bi6396Wee1-like protein kinase2.7.10.20.471
3fwjCAMCamphor 5-monooxygenase1.14.15.10.471
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.471
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.470
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.470
2pg0FADAcyl-CoA dehydrogenase/0.470
2qenADPWalker-Type ATPase/0.470
3t8vBTJM1 family aminopeptidase3.4.110.470
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
1hfqMOTDihydrofolate reductase1.5.1.30.469
1pq944BOxysterols receptor LXR-beta/0.469
2zi53L1Deoxycytidine kinase2.7.1.740.469
3gbuATPUncharacterized sugar kinase PH14592.7.10.469
1me8RVPInosine-5'-monophosphate dehydrogenase/0.468
1zgi382Prothrombin3.4.21.50.468
2a94AP0L-lactate dehydrogenase1.1.1.270.468
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.468
2cftPLPPyridoxal phosphate phosphatase/0.468
2qc8ADPGlutamine synthetase6.3.1.20.468
3b9lAZZSerum albumin/0.468
4aacAAVMitogen-activated protein kinase 14/0.468
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.467
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.466
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.466
2znq401Peroxisome proliferator-activated receptor delta/0.466
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3x2fNAIAdenosylhomocysteinase/0.466
4u0zAPCAdenosine monophosphate-protein transferase FICD2.7.7.n10.466
1knpFADL-aspartate oxidase1.4.3.160.465
2ab8MTPAdenosine kinase2.7.1.200.465
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.465
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.465
3e92G6AMitogen-activated protein kinase 14/0.465
4c02TAKActivin receptor type-12.7.11.300.465
4hyvPEPPyruvate kinase 12.7.1.400.465
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.464
1w7h3IPMitogen-activated protein kinase 14/0.464
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2v59LZKBiotin carboxylase6.3.4.140.464
2vwqNAPGlucose 1-dehydrogenase/0.464
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.464
3k4cFADPyranose 2-oxidase/0.464
3p62FMNPentaerythritol tetranitrate reductase/0.464
3uylTYDProbable NDP-rhamnosyltransferase/0.464
4jlm1NNDeoxycytidine kinase2.7.1.740.464
1esvLARActin, alpha skeletal muscle/0.463
1f123HCHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.463
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.463
2jn3JN3Fatty acid-binding protein, liver/0.463
2rc6NAPFerredoxin--NADP reductase/0.463
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.463
4b45GSPTubulin-like protein CetZ2/0.463
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.463
1h63FMNPentaerythritol tetranitrate reductase/0.462
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.462
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.462
2pl0STITyrosine-protein kinase Lck2.7.10.20.462
3ac1KZITyrosine-protein kinase Lck2.7.10.20.462
3iphG11Mitogen-activated protein kinase 14/0.462
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
5c4cUPGHisto-blood group ABO system transferase/0.462
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
1npvL27Gag-Pol polyprotein3.4.23.160.461
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.461
2he5NDPAldo-keto reductase family 1 member C211.1.10.461
3raiX85Cyclin-dependent kinase 22.7.11.220.461
1h51FMNPentaerythritol tetranitrate reductase/0.460
2bl4NADLactaldehyde reductase1.1.1.770.460
2rtqIMIStreptavidin/0.460
3hv3R49Mitogen-activated protein kinase 14/0.460
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.460
4hxyNDPPlm1/0.460
1vbiNADMalate/L-lactate dehydrogenase family protein/0.459
3c1kT15Prothrombin3.4.21.50.459
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.459
4jln18VDeoxycytidine kinase2.7.1.740.459
4okx198Androgen receptor/0.459
4rosAPRMalate dehydrogenase/0.459
4ea30NNNociceptin receptor/0.459
1bcpATPPertussis toxin subunit 4/0.458
1bcpATPPertussis toxin subunit 5/0.458
1gc5ADPADP-dependent glucokinase2.7.1.1470.458
1u1iNADMyo-inositol-1-phosphate synthase (Ino1)/0.458
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.458
3fmkFMKMitogen-activated protein kinase 14/0.458
4zlaBESCytosol aminopeptidase3.4.11.10.458
1bxoPP7Penicillopepsin-13.4.23.200.457
1xddAAYIntegrin alpha-L/0.457
1z5uCMPClass B acid phosphatase/0.457
2g8yNADHydroxycarboxylate dehydrogenase B/0.457
2rhrEMOPutative ketoacyl reductase1.3.10.457
3ds6A17Mitogen-activated protein kinase 14/0.457
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.457
3mvm39PMitogen-activated protein kinase 14/0.457
3pqbVGPPutative oxidoreductase/0.457
4ienCOAPutative acyl-CoA hydrolase/0.457
4l9q9TPSerum albumin/0.457
3pblETQD(3) dopamine receptor/0.457
1g28FMNPHY3/0.456
1m2oGNPSmall COPII coat GTPase SAR13.6.50.456
2gjlFMNNitronate monooxygenase1.13.12.160.456
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.456
2hk9NAPShikimate dehydrogenase (NADP(+))/0.456
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.456
3angDCCTranscriptional repressor, TetR family/0.456
3itzP66Mitogen-activated protein kinase 14/0.456
3opxU5PSuppressor of disruption of TFIIS/0.456
4l0oPLPCystathionine gamma-synthase2.5.1.480.456
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.456
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.455
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.455
2cjfRP43-dehydroquinate dehydratase4.2.1.100.455
2hu2NADC-terminal binding protein 1/0.455
2qd9LGFMitogen-activated protein kinase 14/0.455
2zi63D1Deoxycytidine kinase2.7.1.740.455
3bx5304Mitogen-activated protein kinase 14/0.455
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.455
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.455
4olfHFGProline--tRNA ligase6.1.1.150.455
1cf2NAPGlyceraldehyde-3-phosphate dehydrogenase/0.454
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.454
1xp8AGSProtein RecA/0.454
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.454
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.454
2rg6287Mitogen-activated protein kinase 14/0.454
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.454
3bv2P38Mitogen-activated protein kinase 14/0.454
3c35KAIGlutamate receptor ionotropic, kainate 1/0.454
3cb2GDPTubulin gamma-1 chain/0.454
3r96ACOMccE protein/0.454
4ramPNMMetallo-beta-lactamase type 2/0.454
4tvbNADHomospermidine synthase2.5.1.440.454
5a8aADPRiboflavin biosynthesis protein RibF2.7.1.260.454
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.453
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.453
2fhnBNIAvidin-related protein 4/5/0.453
3fowIMHPurine nucleoside phosphorylase/0.453
4l5b1UXDeoxycytidine kinase2.7.1.740.453
1h73ANPHomoserine kinase2.7.1.390.452
1twwHH2Dihydropteroate synthase/0.452
1zptFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.452
2balPQAMitogen-activated protein kinase 14/0.452
2jgsBTNAvidin/0.452
3biz61EWee1-like protein kinase2.7.10.20.452
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3gcq1BUMitogen-activated protein kinase 14/0.452
3h3t16HCollagen type IV alpha-3-binding protein/0.452
3pe2E1BCasein kinase II subunit alpha2.7.11.10.452
3sl2ATPSensor histidine kinase WalK/0.452
3vi5M4MHematopoietic prostaglandin D synthase/0.452
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
4xd1T3QQdtf/0.452
4xj43ATCyclic GMP-AMP synthase/0.452
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.451
1obnASVIsopenicillin N synthase1.21.3.10.451
1rfuADPPyridoxal kinase2.7.1.350.451
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.451
2briANPUridylate kinase2.7.4.220.451
2hkoFADLysine-specific histone demethylase 1A10.451
2ohvNHLGlutamate racemase/0.451
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.451
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.451
2vbpVB1Isopenicillin N synthase1.21.3.10.451
3kb6NADD-lactate dehydrogenase/0.451
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.451
4jl5ADPAdenylate kinase/0.451
4v0s2HN3-dehydroquinate dehydratase4.2.1.100.451
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.451
4yj2GTPTubulin alpha-1B chain/0.451
5cvcPLPSerine racemase/0.451
5f1xATP78 kDa glucose-regulated protein/0.451
1dmwHBIPhenylalanine-4-hydroxylase1.14.16.10.450
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1towCRZFatty acid-binding protein, adipocyte/0.450
2fznFADBifunctional protein PutA1.5.5.20.450
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3cgcCOACoenzyme A disulfide reductase/0.450
3fhxPLPPyridoxal kinase2.7.1.350.450
3k8q22APurine nucleoside phosphorylase2.4.2.10.450
3s43478Protease/0.450
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.450
4fhf0TTSpore photoproduct lyase/0.450
4rawZZ7Metallo-beta-lactamase type 2/0.450
4tx9AMZPhosphoribosyl isomerase A/0.450
4w6z8IDAlcohol dehydrogenase 11.1.1.10.450
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.450
1lkeDOGBilin-binding protein/0.449
1pd9CO4Dihydrofolate reductase1.5.1.30.449
1sxjADPReplication factor C subunit 5/0.449
2igoFADPyranose 2-oxidase/0.449
2pk3GDDGDP-6-deoxy-D-mannose reductase/0.449
2v13C40Renin3.4.23.150.449
3bgbLJGGag-Pol polyprotein3.4.23.160.449
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3q33ACOHistone acetyltransferase RTT1092.3.1.480.449
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.449
3vi7CBDHematopoietic prostaglandin D synthase/0.449
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.449
4an4DUDPutative glycosyl transferase/0.449
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.449
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.449
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.449
4oqyNDP(S)-imine reductase/0.449
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.449
1dljUGAUDP-glucose 6-dehydrogenase/0.448
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.448
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.448
1orrNADCDP-paratose 2-epimerase/0.448
1u3wFXYAlcohol dehydrogenase 1C1.1.1.10.448
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.448
2uxhQUEHTH-type transcriptional regulator TtgR/0.448
2vcmM11Isopenicillin N synthase1.21.3.10.448
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.448
2z50028Geranylgeranyl pyrophosphate synthase/0.448
3pd2A3SThreonine--tRNA ligase6.1.1.30.448
4a6bQG8Gag-Pol polyprotein3.4.23.160.448
4bcsBTNAvidin-related protein 4/5/0.448
4k6fNAPPutative Acetoacetyl-CoA reductase/0.448
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.448
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.448
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.448
5dhgDGVNociceptin receptor/0.448
1lbm137N-(5'-phosphoribosyl)anthranilate isomerase5.3.1.240.447
1mueCDDProthrombin3.4.21.50.447
1uxjNADMalate dehydrogenase/0.447
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.447
2zsiGA4Gibberellin receptor GID1A30.447
3fl4FL4Mitogen-activated protein kinase 14/0.447
3ixp834Ecdysone receptor/0.447
3oibFDAPutative acyl-CoA dehydrogenase/0.447
3qt62P0Mevalonate diphosphate decarboxylase/0.447
3r5yF42Uncharacterized protein/0.447
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.447
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.447
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.447
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.447
5c4fUPGHisto-blood group ABO system transferase/0.447
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.447
5cb5APRO-acetyl-ADP-ribose deacetylase/0.447
1a72PADAlcohol dehydrogenase E chain1.1.1.10.446
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.446
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.446
1d6w00RProthrombin3.4.21.50.446
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.446
1k6tXN1Gag-Pol polyprotein3.4.23.160.446
1rszDIHPurine nucleoside phosphorylase2.4.2.10.446
1x8lOXRRetinol dehydratase/0.446
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.446
2c27ACOMycothiol acetyltransferase2.3.1.1890.446
2e8hSAHDiphthine synthase/0.446
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.446
2rr1W8RGenome polyprotein/0.446
2y60M8FIsopenicillin N synthase1.21.3.10.446
2yj4ATPCopper-transporting ATPase/0.446
3c36KAIGlutamate receptor ionotropic, kainate 1/0.446
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.446
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.446
3flwFLWMitogen-activated protein kinase 14/0.446
3iktNADRedox-sensing transcriptional repressor Rex/0.446
3lmhADPMyosin heavy chain kinase A2.7.11.70.446
3lnc5GPGuanylate kinase/0.446
3qczANPDihydrofolate synthase/folylpolyglutamate synthase/0.446
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.446
4ie0PD2Alpha-ketoglutarate-dependent dioxygenase FTO/0.446
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.446
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.446
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.445
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.445
1m51TSXPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.445
1nhtPGSAdenylosuccinate synthetase/0.445
1p4aPCPPur operon repressor/0.445
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1rx8NAPDihydrofolate reductase1.5.1.30.445
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.445
2vwhNAPGlucose 1-dehydrogenase/0.445
3bbrBHYGlutamate receptor 2/0.445
3crzFADFerredoxin--NADP+ reductase/0.445
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.445
3mb714ICasein kinase II subunit alpha2.7.11.10.445
3nbwTR4Ketohexokinase/0.445
3p0fBAUUridine phosphorylase 22.4.2.30.445
3vjoANPEpidermal growth factor receptor2.7.10.10.445
4du82P0Mevalonate diphosphate decarboxylase/0.445
4fhd0TTSpore photoproduct lyase/0.445
4hr2ADPNucleoside diphosphate kinase/0.445
4kugNAD3-hydroxybutyryl-CoA dehydrogenase/0.445
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.445
4rh10TTSpore photoproduct lyase/0.445
5ax35IDMitogen-activated protein kinase 12.7.11.240.445
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.445
1cs4FOKAdenylate cyclase type 2/0.444
1cs4FOKAdenylate cyclase type 5/0.444
1e1lNAPNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.444
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.444
1g7vPAI2-dehydro-3-deoxyphosphooctonate aldolase2.5.1.550.444
1hwlADP3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.444
1trkTPPTransketolase 12.2.1.10.444
1w1wAGSStructural maintenance of chromosomes protein 1/0.444
1wur8DGGTP cyclohydrolase 1/0.444
1xelUPGUDP-glucose 4-epimerase5.1.3.20.444
2ahrNAPPyrroline-5-carboxylate reductase/0.444
2c29NAPDihydroflavonol 4-reductase/0.444
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2ewvADPTwitching motility protein PilT/0.444
2i0aMUIProtease/0.444
2ptfFMNUncharacterized protein MTH_863/0.444
2q5qKPVIndole-3-pyruvate decarboxylase4.1.1.740.444
2qfvNAPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.444
2tprFADTrypanothione reductase1.8.1.120.444
2y9qANPMitogen-activated protein kinase 12.7.11.240.444
3e8xNAPBH1520 protein/0.444
3elm24FCollagenase 33.4.240.444
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.444
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3rinI2OMitogen-activated protein kinase 14/0.444
3s41S41Glucokinase2.7.1.20.444
3to6LYS_CMCHistone acetyltransferase ESA1/0.444
3u9eCOALmo1369 protein/0.444
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.444
4enhFVXCholesterol 24-hydroxylase/0.444
4euc0RQSuccinyl-CoA:acetate CoA-transferase/0.444
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
1ay0TPPTransketolase 12.2.1.10.443
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.443
1kzkJE2Gag-Pol polyprotein3.4.23.160.443
1rfqLARActin, alpha skeletal muscle/0.443
1u5cBIKL-lactate dehydrogenase1.1.1.270.443
1vsoAT1Glutamate receptor ionotropic, kainate 1/0.443
2c42TPPPyruvate synthase/0.443
2ekaSAHDiphthine synthase/0.443
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.443
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.443
2nnqT4BFatty acid-binding protein, adipocyte/0.443
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.443
2pauD5M5'-deoxynucleotidase YfbR/0.443
2vwx7X4Ephrin type-B receptor 42.7.10.10.443
2xlrFADPutative flavin-containing monooxygenase/0.443
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.443
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
3g1lRF2HTH-type transcriptional regulator EthR/0.443
3gonANPPhosphomevalonate kinase/0.443
3l9hEMQKinesin-like protein KIF11/0.443
3nu5478Gag-Pol polyprotein3.4.23.160.443
3qftNAPNADPH--cytochrome P450 reductase/0.443
3wrmCAMCamphor 5-monooxygenase1.14.15.10.443
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.443
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.443
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.443
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
4nu0AP5Adenylate kinase/0.443
4opiFDAConserved Archaeal protein/0.443
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.443
5k2aZMAAdenosine receptor A2a/0.443
1klkPMDDihydrofolate reductase1.5.1.30.442
1mjbACOHistone acetyltransferase ESA1/0.442
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.442
1oc1ASVIsopenicillin N synthase1.21.3.10.442
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.442
1rc0KT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.442
1suiFRECaffeoyl-CoA O-methyltransferase2.1.1.1040.442
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
1zdfUPGGlycogenin-12.4.1.1860.442
2a5kAZPReplicase polyprotein 1ab3.4.220.442
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.442
2ignFADPyranose 2-oxidase/0.442
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.442
2xyuQ9GEphrin type-A receptor 42.7.10.10.442
2yeiXQIHeat shock protein HSP 90-alpha/0.442
3c3eFO12-phospho-L-lactate transferase/0.442
3d2mCOAAmino-acid acetyltransferase/0.442
3gwdFADCyclohexanone monooxygenase/0.442
3litE15Protease/0.442
3lsiFADPyranose 2-oxidase/0.442
3p9tTCLRepressor/0.442
3t94MTAS-methyl-5'-thioadenosine phosphorylase/0.442
3w0iO11Vitamin D3 receptor/0.442
4ck2NVUIntegrase/0.442
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.442
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.442
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.442
4rww2BALmo2692 protein/0.442
5e8xSTUTGF-beta receptor type-12.7.11.300.442
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.442
8catNDPCatalase1.11.1.60.442
5jtbZMAAdenosine receptor A2a/0.442
1f06NDPMeso-diaminopimelate D-dehydrogenase1.4.1.160.441
1f3pFADFerredoxin reductase/0.441
1ja0NAPNADPH--cytochrome P450 reductase/0.441
1l8qADPChromosomal replication initiator protein DnaA/0.441
1omoNADAlanine dehydrogenase/0.441
1rx8FOLDihydrofolate reductase1.5.1.30.441
1t87CAMCamphor 5-monooxygenase1.14.15.10.441
1xe55FEPlasmepsin-23.4.23.390.441
2a9z26AAdenosine kinase2.7.1.200.441
2abbFMNPentaerythritol tetranitrate reductase/0.441
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.441
2hb8MVDVitamin D3 receptor/0.441
2ojg19AMitogen-activated protein kinase 12.7.11.240.441
2pdaTPPPyruvate synthase/0.441
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.441
2qu5276Vascular endothelial growth factor receptor 22.7.10.10.441
2uuk897Prothrombin3.4.21.50.441
2wedPP6Penicillopepsin-13.4.23.200.441
2xvu9DNSerum albumin/0.441
2y0mACOHistone acetyltransferase KAT8/0.441
2zjwREFCasein kinase II subunit alpha2.7.11.10.441
3ekuCY9Actin-5C/0.441
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3h3r14HCollagen type IV alpha-3-binding protein/0.441
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.441
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.441
3t3c017Gag-Pol polyprotein3.4.23.160.441
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.441
4bb3KKAIsopenicillin N synthase1.21.3.10.441
4bqyFNTEgl nine homolog 1/0.441
4f6rGDPTubulin beta chain/0.441
4mv8ACPBiotin carboxylase6.3.4.140.441
4rvnCOAPhenylacetate-coenzyme A ligase/0.441
5e8wSTUTGF-beta receptor type-12.7.11.300.441
1febFADTrypanothione reductase1.8.1.120.440
1i59ANPChemotaxis protein CheA2.7.13.30.440
1kvkATPMevalonate kinase2.7.1.360.440
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.440
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.440
1u2yGOXPancreatic alpha-amylase/0.440
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
2a84ATPPantothenate synthetase6.3.2.10.440
2b53D23Cyclin-dependent kinase 22.7.11.220.440
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2cbrA80Cellular retinoic acid-binding protein 1/0.440
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.440
2itxANPEpidermal growth factor receptor2.7.10.10.440
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2rabFADGlutathione amide reductase/0.440
2v1aFMNNPH1-1/0.440
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2y6fM9FIsopenicillin N synthase1.21.3.10.440
2zjuIM4Acetylcholine-binding protein/0.440
3cr0809Wee1-like protein kinase2.7.10.20.440
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.440
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.440
3h3fNAIL-lactate dehydrogenase A chain1.1.1.270.440
3lqfNADGalactitol dehydrogenase/0.440
3mpt1GKMitogen-activated protein kinase 14/0.440
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3otwCOAPhosphopantetheine adenylyltransferase/0.440
3zoiM2WIsopenicillin N synthase1.21.3.10.440
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.440
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.440
4k9nTZDBenzoylformate decarboxylase4.1.1.70.440
4k9oTPPBenzoylformate decarboxylase4.1.1.70.440
4kiq1RAMitogen-activated protein kinase 14/0.440
4oznATPAmmonium transporter/0.440
4xgxADPFAD:protein FMN transferase/0.440