sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1l4e | RBZ | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1l4e | RBZ | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 1.000 | |
| 1l4l | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.677 | |
| 1jhr | P2P | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.654 | |
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.631 | |
| 1l4h | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.629 | |
| 1d0v | RBZ | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.596 | |
| 1l5k | 1RB | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.573 | |
| 1jha | AAM | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.571 | |
| 1l4k | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.563 | |
| 1l4f | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.553 | |
| 1l4g | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.551 | |
| 1l5o | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.507 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.502 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.496 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.494 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.492 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.487 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.485 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.483 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.482 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.481 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.480 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.479 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.476 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.475 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.475 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.475 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.474 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.474 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.474 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.473 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.473 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.473 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.472 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.472 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.472 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.471 | |
| 3d1z | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.470 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.470 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.469 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2ccu | 2D9 | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.469 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1ebk | 0Q4 | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.468 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.468 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.467 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.467 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.467 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.467 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.467 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.467 | |
| 1vij | BAY | Gag-Pol polyprotein | / | 0.466 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.466 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.465 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.465 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.465 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.465 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.465 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.465 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.465 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.465 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.464 | |
| 3cr3 | ADP | PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.464 | |
| 4ajp | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.464 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.463 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.463 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.463 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.463 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.463 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.463 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.462 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.462 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.462 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 3a20 | FMN | FMN-binding protein | / | 0.462 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.462 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.461 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.461 | |
| 2izt | 23D | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.461 | |
| 2qhc | AB1 | Protease | / | 0.461 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.461 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.461 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 3r95 | ACO | MccE protein | / | 0.461 | |
| 1aj8 | COA | Citrate synthase | / | 0.460 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.460 | |
| 1n49 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.460 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.460 | |
| 3bnk | FMN | Flavoredoxin | / | 0.460 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3sab | F78 | Protease | / | 0.460 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.460 | |
| 2p3c | 3TL | Protease | / | 0.459 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.459 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.459 | |
| 4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4gfv | PRO_GLU_LEU_THR_PTR | Tyrosine-protein phosphatase non-receptor type 18 | 3.1.3.48 | 0.459 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.459 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.459 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.459 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.458 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.458 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.458 | |
| 3el0 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4hj6 | FMN | LOV protein | / | 0.458 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.458 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.457 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.457 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 2fdd | 385 | Pol protein | / | 0.457 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.457 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3gi6 | D78 | Gag-Pol polyprotein | / | 0.457 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.457 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4ccz | THG | Methionine synthase | 2.1.1.13 | 0.457 | |
| 4ema | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4er6 | AW2 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.457 | |
| 1bdq | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 1c6z | ROC | Protease | / | 0.456 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1eag | A70 | Candidapepsin-2 | 3.4.23.24 | 0.456 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.456 | |
| 2chl | DKI | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.456 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.456 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.456 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.456 | |
| 3nwq | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.456 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.456 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.456 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.455 | |
| 1ptj | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.455 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.455 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.455 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.455 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.455 | |
| 2hs1 | 017 | Protease | / | 0.455 | |
| 2i4x | KGQ | Protease | / | 0.455 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.455 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.455 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.455 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.455 | |
| 4bn1 | ADP | Aurora kinase A | 2.7.11.1 | 0.455 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.455 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.455 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 5da9 | AGS | Uncharacterized protein | / | 0.455 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.454 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.454 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.454 | |
| 2eva | ADN | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.454 | |
| 2q5k | AB1 | Protease | / | 0.454 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.454 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.454 | |
| 3evb | SAH | Genome polyprotein | 2.1.1.56 | 0.454 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.454 | |
| 4aac | AAV | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.454 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.454 | |
| 5it1 | 2OH | Putative cytochrome P450 | / | 0.454 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1hih | C20 | Gag-Pol polyprotein | / | 0.453 | |
| 1hpx | KNI | Gag-Pol polyprotein | / | 0.453 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.453 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.453 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.453 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.453 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.453 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.453 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.453 | |
| 3lki | ATP | Fructokinase | / | 0.453 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.453 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.453 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.453 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.453 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 1qy8 | RDI | Endoplasmin | / | 0.452 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.452 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.452 | |
| 2p3b | 3TL | V-1 protease | / | 0.452 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2y3s | TIR | TamL | / | 0.452 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.452 | |
| 3kdb | 006 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3liq | E14 | Protease | / | 0.452 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.452 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.452 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.452 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.452 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.452 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1hpv | 478 | Gag-Pol polyprotein | / | 0.451 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1z0f | GDP | Ras-related protein Rab-14 | / | 0.451 | |
| 2fsv | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.451 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.451 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2pzi | AXX | Serine/threonine-protein kinase PknG | 2.7.11.1 | 0.451 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.451 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.451 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.451 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.451 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 3w23 | 3RO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.451 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.451 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.450 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.450 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.450 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.450 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3i81 | EBI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.450 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.450 | |
| 3saa | 77F | Protease | / | 0.450 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.450 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.450 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.449 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 1hsg | MK1 | Gag-Pol polyprotein | / | 0.449 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 2bpy | 3IN | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.449 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.449 | |
| 3eld | SFG | Methyltransferase | / | 0.449 | |
| 3h8b | NSY | Cathepsin L1 | 3.4.22.15 | 0.449 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3qro | NK9 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.449 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.449 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.449 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.449 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4njs | G08 | Protease | / | 0.449 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.449 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.449 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.448 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.448 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.448 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.448 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 1wbm | BLL | Pol protein | / | 0.448 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.448 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2f2u | M77 | Rho-associated protein kinase 2 | 2.7.11.1 | 0.448 | |
| 2f3k | RO1 | Protease | / | 0.448 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.448 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3ieu | GDP | GTPase Era | / | 0.448 | |
| 3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.448 | |
| 3sa6 | F71 | Protease | / | 0.448 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.448 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.448 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 4eht | ADP | 2-hydroxyisocaproyl-CoA dehydratase activator | / | 0.448 | |
| 1d4h | BEH | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.447 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.447 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 0.447 | |
| 1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.447 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1t57 | FMN | Conserved protein | / | 0.447 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2emr | SAH | Diphthine synthase | / | 0.447 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.447 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.447 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.447 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.447 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.447 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.447 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3w2j | QRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.447 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.447 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.447 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.447 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.447 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.447 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.447 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1d7a | AIR | N5-carboxyaminoimidazole ribonucleotide mutase | / | 0.446 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.446 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1hiv | 1ZK | Gag-Pol polyprotein | / | 0.446 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1m2h | APR | NAD-dependent protein deacylase 1 | / | 0.446 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.446 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.446 | |
| 2huq | SAH | Diphthine synthase | / | 0.446 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.446 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.446 | |
| 3ggx | GGX | Gag-Pol polyprotein | / | 0.446 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.446 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.446 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.446 | |
| 3pwr | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3qcy | 3Q3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3sa3 | 23X | Protease | / | 0.446 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.446 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.446 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.446 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.445 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.445 | |
| 1ody | LP1 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.445 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.445 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.445 | |
| 2egs | SAH | Diphthine synthase | / | 0.445 | |
| 2qi0 | MZ3 | Gag-Pol polyprotein | / | 0.445 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.445 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.445 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3gi4 | K60 | Gag-Pol polyprotein | / | 0.445 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.445 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.445 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.445 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3w1x | XRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.445 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.445 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.445 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 4el0 | D1K | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.445 | |
| 4hla | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.445 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.445 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.445 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.445 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.445 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1llu | NAD | Alcohol dehydrogenase | / | 0.444 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1pro | A88 | Gag-Pol polyprotein | / | 0.444 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.444 | |
| 2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2q54 | MU1 | Protease | / | 0.444 | |
| 3bxz | ADP | Protein translocase subunit SecA | / | 0.444 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.444 | |
| 3gb2 | G3B | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.444 | |
| 3lzu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.444 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.444 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4ros | APR | Malate dehydrogenase | / | 0.444 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.443 | |
| 1f0y | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.443 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.443 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t3r | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1wbk | 568 | Pol protein | / | 0.443 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.443 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.443 | |
| 2dxw | SAH | Diphthine synthase | / | 0.443 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.443 | |
| 2r5q | 1UN | Gag-Pol polyprotein | / | 0.443 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.443 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 3bxs | DRS | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3sa5 | A69 | Protease | / | 0.443 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4gkm | 683 | Anthranilate phosphoribosyltransferase | / | 0.443 | |
| 4h3y | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.443 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.443 | |
| 4lb2 | DM5 | Serum albumin | / | 0.443 | |
| 5cyo | GDP | Septin-9 | / | 0.443 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.442 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.442 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.442 | |
| 1ndi | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.442 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1vc2 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.442 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.442 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2ele | SAH | Diphthine synthase | / | 0.442 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.442 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3a2o | KNJ | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.442 | |
| 3d1y | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.442 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.442 | |
| 3pwm | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3qaa | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3vfb | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.442 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4j55 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.442 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.442 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.441 | |
| 1kev | NDP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.441 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1rbq | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.441 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1w5y | BE6 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1zys | 199 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2dbr | NAP | Glyoxylate reductase | 1.1.1.26 | 0.441 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.441 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.441 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.441 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.441 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.441 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.441 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.441 | |
| 4eyf | PNK | Metallo-beta-lactamase type 2 | / | 0.441 | |
| 4f08 | 1RS | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.441 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.441 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.441 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.441 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.441 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.441 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.440 | |
| 1g9c | BAB | Botulinum neurotoxin type B | 3.4.24.69 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.440 | |
| 1mgo | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1sez | OMN | Protoporphyrinogen oxidase, mitochondrial | 1.3.3.4 | 0.440 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.440 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.440 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.440 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.440 | |
| 2q55 | MU0 | Protease | / | 0.440 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3ok9 | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.440 | |
| 3ttp | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3vf7 | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4eh6 | 0ON | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.440 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.440 |