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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4yl2FMNLactate oxidase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4yl2FMNLactate oxidase/1.000
2e77FMNLactate oxidase/0.687
4rjeFNRLactate oxidase/0.628
2j6xFMNLactate oxidase/0.624
2nliFMNLactate oxidase/0.618
5ebuFMNLactate oxidase/0.602
1goxFMNPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.582
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.580
2du2FMNLactate oxidase/0.579
2zfaFMNLactate oxidase/0.573
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.571
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.562
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.559
1bwlFMNNADPH dehydrogenase 11.6.99.10.535
1szgFNSCytochrome b2, mitochondrial1.1.2.30.531
1szfFMNCytochrome b2, mitochondrial1.1.2.30.523
1z48FMNNADPH dehydrogenase/0.521
1bwkFMNNADPH dehydrogenase 11.6.99.10.517
1h50FMNPentaerythritol tetranitrate reductase/0.517
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.516
1icsFMN12-oxophytodienoate reductase 11.3.1.420.513
4h6kFMNNADPH dehydrogenase 11.6.99.10.513
2oz0FMNCytochrome b2, mitochondrial1.1.2.30.510
3p62FMNPentaerythritol tetranitrate reductase/0.510
3p82FMNPentaerythritol tetranitrate reductase/0.508
1h63FMNPentaerythritol tetranitrate reductase/0.506
1vyrFMNPentaerythritol tetranitrate reductase/0.506
1oyaFMNNADPH dehydrogenase 11.6.99.10.505
3f03FMNPentaerythritol tetranitrate reductase/0.503
3p8jFMNPentaerythritol tetranitrate reductase/0.501
1vjiFMN12-oxophytodienoate reductase 11.3.1.420.498
1oycFMNNADPH dehydrogenase 11.6.99.10.495
1fxsNAPGDP-L-fucose synthase/0.494
3bw4FMNPutative 2-nitropropane dioxygenase/0.494
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.491
4rnxFMNNADPH dehydrogenase 11.6.99.10.491
4e2bFMNDehydrogenase/0.490
1icqFMN12-oxophytodienoate reductase 11.3.1.420.488
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.488
3p84FMNPentaerythritol tetranitrate reductase/0.487
1h51FMNPentaerythritol tetranitrate reductase/0.483
4tmcFMNOld yellow enzyme/0.483
2zdt46CMitogen-activated protein kinase 102.7.11.240.482
3x2uATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
4m5pFMNNADPH dehydrogenase/0.482
1icpFMN12-oxophytodienoate reductase 11.3.1.420.481
2abbFMNPentaerythritol tetranitrate reductase/0.481
1z41FMNNADPH dehydrogenase/0.479
3hf3FMNChromate reductase/0.479
4awsFMNNADH:flavin oxidoreductase Sye1/0.479
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.479
5j23A2RPutative 2-hydroxyacid dehydrogenase/0.479
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.478
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.478
3qh23NMThiazole tautomerase/0.478
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.478
4tmbFMNOld yellow enzyme/0.478
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
3p74FMNPentaerythritol tetranitrate reductase/0.476
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.476
4rnuFMNNADPH dehydrogenase 11.6.99.10.476
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.475
3l5lFMNXenobiotic reductase/0.475
4awtFMNNADH:flavin oxidoreductase Sye1/0.475
4fdpFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.475
4r3kCOAN-alpha-acetyltransferase2.3.10.475
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.475
2gouFMNNADH:flavin oxidoreductase Sye1/0.474
3tqhNDPQuinone oxidoreductase/0.474
4e5kNADPhosphonate dehydrogenase1.20.1.10.474
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.474
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.473
2ywwATPAspartate carbamoyltransferase regulatory chain/0.473
3bw2FMNPutative 2-nitropropane dioxygenase/0.473
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
4dymIYZActivin receptor type-12.7.11.300.473
3oev3OEProteasome subunit beta type-53.4.25.10.472
3oev3OEProteasome subunit beta type-63.4.25.10.472
4jicFMNGTN Reductase/0.472
4mlp2CXCryptochrome-2/0.472
1qcwFNSCytochrome b2, mitochondrial1.1.2.30.471
2gqaFMNNADH:flavin oxidoreductase Sye1/0.471
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.471
3lgxATPD-alanine--poly(phosphoribitol) ligase subunit 1/0.471
4df2FMNNADPH dehydrogenase/0.471
4e5nNADPhosphonate dehydrogenase1.20.1.10.471
5cwa0GAAnthranilate synthase component 14.1.3.270.470
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.469
1v0pPVBCell division control protein 2 homolog2.7.11.220.469
1z44FMNNADPH dehydrogenase/0.469
3gwfFADCyclohexanone monooxygenase/0.469
4rnwFMNNADPH dehydrogenase 11.6.99.10.469
4utkFNRXenobiotic reductase/0.469
1adfTADAlcohol dehydrogenase E chain1.1.1.10.468
3gr8FMNNADPH dehydrogenase/0.468
3o153NMThiamine-phosphate synthase/0.468
1bwsNDPGDP-L-fucose synthase/0.467
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.467
2g0nGDPRas-related C3 botulinum toxin substrate 3/0.467
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.467
4hmvWUBPhenazine biosynthesis protein PhzG1.40.467
4k7yFMNNADPH dehydrogenase 11.6.99.10.467
2w98P1ZProstaglandin reductase 21.3.1.480.466
5ikrID8Prostaglandin G/H synthase 21.14.99.10.466
1bsvNDPGDP-L-fucose synthase/0.465
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.465
3cukFADD-amino-acid oxidase1.4.3.30.465
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.465
3n19FNRXenobiotic reductase/0.465
3nl6TPSUncharacterized protein/0.465
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.465
1nvtNAPShikimate dehydrogenase (NADP(+))/0.464
2c27ACOMycothiol acetyltransferase2.3.1.1890.464
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2rghFADAlpha-Glycerophosphate Oxidase/0.464
3mqe416Prostaglandin G/H synthase 21.14.99.10.464
3p67FMNPentaerythritol tetranitrate reductase/0.464
1e3eNAIAlcohol dehydrogenase 41.1.1.10.463
1gjvAGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial2.7.11.40.463
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.463
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.463
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.463
3ddw055Glycogen phosphorylase, liver form2.4.1.10.463
3vrwYS5Vitamin D3 receptor/0.463
3vt8YI3Vitamin D3 receptor/0.463
3w5rLOAVitamin D3 receptor/0.463
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.463
4ejmNAPPutative zinc-binding dehydrogenase/0.463
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.463
2xuuADPDeath-associated protein kinase 12.7.11.10.462
4nxxGDPMitochondrial dynamics protein MID51/0.462
4q71FADBifunctional protein PutA/0.462
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.461
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.461
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.461
4dieC5PCytidylate kinase/0.461
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.461
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.461
4l8u9AZSerum albumin/0.461
4q4kFMNUncharacterized protein/0.461
1l7eNAINAD(P) transhydrogenase subunit alpha part 11.6.1.20.460
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2cy0NAPShikimate dehydrogenase (NADP(+))/0.460
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.460
2lbaCHOFatty acid binding protein 6/0.460
3mtfA3FActivin receptor type-12.7.11.300.460
3t8wDGZM17 leucyl aminopeptidase/0.460
1llzFMNFerredoxin-dependent glutamate synthase 21.4.7.10.459
1nytNAPShikimate dehydrogenase (NADP(+))/0.459
1udaUFGUDP-glucose 4-epimerase5.1.3.20.459
2qo9ANPEphrin type-A receptor 32.7.10.10.459
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.459
2vww7X2Ephrin type-B receptor 42.7.10.10.459
3atzFMNProstaglandin F2a synthase/0.459
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.459
3hyoADPPyridoxal kinase/0.459
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.459
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.459
4f9fGDPPutative glycosyltransferase/0.459
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.459
4itfTFYVitamin D3 receptor/0.459
5ikqJMSProstaglandin G/H synthase 21.14.99.10.459
1dj3GDPAdenylosuccinate synthetase, chloroplastic/0.458
1s5kCOAAminoglycoside N(6')-acetyltransferase type 1/0.458
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.458
3atyFMNProstaglandin F2a synthase/0.458
3q7fED2Uncharacterized protein/0.458
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.458
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.458
4oauADP2-5A-dependent ribonuclease3.1.260.458
4utlFNRXenobiotic reductase/0.458
4z38FMNMlnA/0.458
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2wotZZGTGF-beta receptor type-12.7.11.300.457
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3cvuFADRE11660p/0.457
3dds26BGlycogen phosphorylase, liver form2.4.1.10.457
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.457
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.457
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.457
4dpmCOAMalonyl-CoA reductase1.2.1.750.457
4g2fC07Ephrin type-A receptor 32.7.10.10.457
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.457
1fq1ATPCyclin-dependent kinase 22.7.11.220.456
1h7wFMNDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.456
1j49NADD-lactate dehydrogenase1.1.1.280.456
2eixFADNADH-cytochrome b5 reductase/0.456
2tpsTPSThiamine-phosphate synthase/0.456
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.456
3w3oROEDihydroorotate dehydrogenase (fumarate)1.3.98.10.456
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.456
4e2dFMNDehydrogenase/0.456
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.456
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
1zaoATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.455
1zemNADXylitol dehydrogenase/0.455
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2dr3ADPUPF0273 protein PH0284/0.455
2geuCOKPantothenate kinase2.7.1.330.455
2w02ATPAcsD/0.455
3gxlQIGTGF-beta receptor type-12.7.11.300.455
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4m9aFDAAcyl-CoA dehydrogenase/0.455
4nxwADPMitochondrial dynamics protein MID51/0.455
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.455
4xnw2IDP2Y purinoceptor 1/0.455
1lm1FMNFerredoxin-dependent glutamate synthase 21.4.7.10.454
1u4dDBQActivated CDC42 kinase 1/0.454
1x2hLPALipoate-protein ligase A6.3.1.200.454
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.454
2zkjADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.454
3oom507Activin receptor type-12.7.11.300.454
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.454
4qaiFMNNADPH dehydrogenase/0.454
4rnvFMNNADPH dehydrogenase 11.6.99.10.454
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.454
1g4tFTPThiamine-phosphate synthase/0.453
1s3zCOAAminoglycoside N(6')-acetyltransferase type 1/0.453
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.453
2j4dFADCryptochrome DASH, chloroplastic/mitochondrial/0.453
2y882ERPhosphoribosyl isomerase A5.3.1.160.453
3idbANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3te4ACODopamine N-acetyltransferase/0.453
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4n57ADPAPH(2'')-Id/0.453
4qnwFMNChanoclavine-I aldehyde reductase easA/0.453
1j1zATPArgininosuccinate synthase/0.452
1j7uANPAminoglycoside 3'-phosphotransferase2.7.1.950.452
1nzdUPGDNA beta-glucosyltransferase/0.452
1xq6NAPUncharacterized protein At5g02240/0.452
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.452
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
3i0pNADMalate dehydrogenase, putative/0.452
3kb6NADD-lactate dehydrogenase/0.452
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.452
4e5j581Polymerase acidic protein/0.452
1llwFMNFerredoxin-dependent glutamate synthase 21.4.7.10.451
1nzfUPGDNA beta-glucosyltransferase/0.451
2a4lRRCCyclin-dependent kinase 22.7.11.220.451
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.451
2ev9NAPShikimate dehydrogenase (NADP(+))/0.451
2vcmM11Isopenicillin N synthase1.21.3.10.451
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.451
2zdu446Mitogen-activated protein kinase 102.7.11.240.451
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.451
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.451
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.451
3qarQARPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3rr3FLRProstaglandin G/H synthase 21.14.99.10.451
3sf6FDAGlutaryl-CoA dehydrogenase/0.451
4bgg844Activin receptor type-12.7.11.300.451
4ekkANPRAC-alpha serine/threonine-protein kinase2.7.11.10.451
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4hjfC2EGGDEF family protein/0.451
4i02CMPcAMP-activated global transcriptional regulator CRP/0.451
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.451
1m13HYFNuclear receptor subfamily 1 group I member 2/0.450
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.450
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.450
3c3xNAPEugenol synthase 11.1.1.3180.450
3nszANPCasein kinase II subunit alpha2.7.11.10.450
3p8iFMNPentaerythritol tetranitrate reductase/0.450
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.450
3twoNDPMannitol dehydrogenase/0.450
4coxIMNProstaglandin G/H synthase 21.14.99.10.450
4i6gFADCryptochrome-2/0.450
4nxuADPMitochondrial dynamics protein MID51/0.450
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.449
1u3cFADCryptochrome-1/0.449
2d29FADAcyl-CoA dehydrogenase/0.449
2g8yNADHydroxycarboxylate dehydrogenase B/0.449
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.449
2qocANPEphrin type-A receptor 32.7.10.10.449
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
2vwz7X6Ephrin type-B receptor 42.7.10.10.449
3cf0ADPTransitional endoplasmic reticulum ATPase3.6.4.60.449
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.449
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.449
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.449
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4gk3L87Ephrin type-A receptor 32.7.10.10.449
4iae1DXAlr2278 protein/0.449
4lutDCSAlanine racemase/0.449
4nmdFDABifunctional protein PutA/0.449
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.449
4ruoBIVVitamin D3 receptor A/0.449
4tl7ATPCircadian clock protein kinase KaiC2.7.11.10.449
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.449
4zohFADPutative oxidoreductase FAD-binding subunit/0.449
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.448
1likADNAdenosine kinase2.7.1.200.448
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
1q4u4CA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
2b1pAIZMitogen-activated protein kinase 102.7.11.240.448
2dfvNADL-threonine 3-dehydrogenase/0.448
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.448
2wq7FADRE11660p/0.448
3sdkP3NProteasome subunit beta type-53.4.25.10.448
3sdkP3NProteasome subunit beta type-63.4.25.10.448
3uwqU5POrotidine 5'-phosphate decarboxylase/0.448
3vrvYSDVitamin D3 receptor/0.448
4h6rFDAProline dehydrogenase/0.448
4kh0ATPAspartate carbamoyltransferase regulatory chain {ECO:0000256|HAMAP-Rule:MF_00002}/0.448
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.448
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.448
5ckuNAPL-ornithine N(5)-monooxygenase/0.448
1mezGDPAdenylosuccinate synthetase isozyme 1/0.447
1tj0FADBifunctional protein PutA1.5.5.20.447
1wn3HXCPhenylacetic acid degradation protein PaaI/0.447
2oapANPType II secretion system protein (GspE-2)/0.447
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.447
2x0rNADMalate dehydrogenase/0.447
3f7bAG5Carbonic anhydrase 44.2.1.10.447
3qx2X63Cyclin-dependent kinase 22.7.11.220.447
4a0mNADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.447
4n9wGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.447
4uthFMNXenobiotic reductase/0.447
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1kifFADD-amino-acid oxidase1.4.3.30.446
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.446
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.446
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.446
2oyuIMSProstaglandin G/H synthase 11.14.99.10.446
2p5uNADUDP-glucose 4-epimerase/0.446
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.446
3cgeCOACoenzyme A disulfide reductase/0.446
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.446
3jzdNADMaleylacetate reductase/0.446
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.446
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.446
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.446
5bqfNAPProbable hydroxyacid dehydrogenase protein/0.446
3sn6P0GBeta-2 adrenergic receptor/0.446
1dj2GDPAdenylosuccinate synthetase, chloroplastic/0.445
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.445
1o6kANPRAC-beta serine/threonine-protein kinase2.7.11.10.445
1uyePU9Heat shock protein HSP 90-alpha/0.445
1xjnDTPVitamin B12-dependent ribonucleotide reductase/0.445
2bunFADAppA protein/0.445
2iyaZIOOleandomycin glycosyltransferase/0.445
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.445
3copADPGlycogen synthase2.4.1.210.445
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.445
3pjtC2EDiguanylate cyclase/phosphodiesterase/0.445
3x2vATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.444
1ny5ADPTranscriptional regulator (NtrC family)/0.444
1p9wANPType II secretion system protein E/0.444
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.444
2eklNADD-3-phosphoglycerate dehydrogenase/0.444
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.444
2iw84SPCyclin-dependent kinase 22.7.11.220.444
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2x0iNAIMalate dehydrogenase/0.444
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.444
3cndFADPolyamine oxidase FMS1/0.444
3enkUPGUDP-glucose 4-epimerase/0.444
4gk2L66Ephrin type-A receptor 32.7.10.10.444
4kxl6C62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.444
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
5a05NDPGlucose-fructose oxidoreductase/0.444
1a2nTETUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
1fmlRTLRetinol dehydratase/0.443
1hb1OCVIsopenicillin N synthase1.21.3.10.443
1j39UPGDNA beta-glucosyltransferase/0.443
1me6IVSPlasmepsin-23.4.23.390.443
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.443
2bxfDZPSerum albumin/0.443
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.443
2q7vFADThioredoxin reductase/0.443
2w9hTOPDihydrofolate reductase1.5.1.30.443
2wq6FADRE11660p/0.443
2xgs44PUncharacterized protein/0.443
3adaNADSubunit alpha of sarocosine oxidase/0.443
3eej53RUncharacterized protein/0.443
3gkaFMNN-ethylmaleimide reductase/0.443
3i59N6SCRP-like cAMP-activated global transcriptional regulator/0.443
3kr6UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
3ntaCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.443
3o7lANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3oibFDAPutative acyl-CoA dehydrogenase/0.443
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.443
3pe2E1BCasein kinase II subunit alpha2.7.11.10.443
3phiNDPShikimate dehydrogenase (NADP(+))/0.443
3sdi3SDProteasome subunit beta type-53.4.25.10.443
3sdi3SDProteasome subunit beta type-63.4.25.10.443
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.443
4c4oNADSADH/0.443
4c57FEFCyclin-G-associated kinase2.7.11.10.443
4e730NRMitogen-activated protein kinase 82.7.11.240.443
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.443
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.443
4l9kEHFSerum albumin/0.443
4xiwAZMCarbonic anhydrase, alpha type/0.443
5ce3ADPProtein kinase YopO/0.443
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1ofeFMNFerredoxin-dependent glutamate synthase 21.4.7.10.442
1s60COAAminoglycoside N(6')-acetyltransferase type 1/0.442
1wlvCOAPhenylacetic acid degradation protein PaaI/0.442
1x7gNAPPutative ketoacyl reductase1.3.10.442
2fzwNADAlcohol dehydrogenase class-31.1.1.10.442
2hamC33Vitamin D3 receptor/0.442
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2y9qANPMitogen-activated protein kinase 12.7.11.240.442
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.442
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
3ixj586Beta-secretase 13.4.23.460.442
3mgdACOPredicted acetyltransferase/0.442
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.442
3rv6VAESalicylate synthase/0.442
3sjzGNPTranslation initiation factor 2 subunit gamma/0.442
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.442
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.442
4ycpFMNtRNA-dihydrouridine(16) synthase/0.442
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.442
5cb4ACPTubulin tyrosine ligase/0.442
5ccyTMPPolymerase acidic protein/0.442
5eowFAD6-hydroxynicotinate 3-monooxygenase1.14.13.1140.442
1c2tGARPhosphoribosylglycinamide formyltransferase/0.441
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1gqtACPRibokinase/0.441
1i9c5ADGlutamate mutase epsilon subunit/0.441
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.441
1ofdFMNFerredoxin-dependent glutamate synthase 21.4.7.10.441
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.441
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.441
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.441
2bxoOPBSerum albumin/0.441
2wdzNADGalactitol dehydrogenase/0.441
2xvv9DNSerum albumin/0.441
3b03VNRIsopentenyl-diphosphate delta-isomerase/0.441
3gfbNADL-threonine 3-dehydrogenase/0.441
3k4nFADPyranose 2-oxidase/0.441
3oetNADErythronate-4-phosphate dehydrogenase/0.441
3pd4A3GThreonine--tRNA ligase6.1.1.30.441
3qqlX03Cyclin-dependent kinase 22.7.11.220.441
3vtdTKDVitamin D3 receptor/0.441
4ambDUDPutative glycosyl transferase/0.441
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4bfyZVYPantothenate kinase2.7.1.330.441
4gyiADPUncharacterized protein/0.441
4h4wNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.441
4in44IDKelch-like ECH-associated protein 1/0.441
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.441
4jqlVJ6Heat shock protein HSP 90-alpha/0.441
4ki8ADP60 kDa chaperonin/0.441
4nt03DUOrotidine 5'-phosphate decarboxylase4.1.1.230.441
4nu5NADPhosphonate dehydrogenase1.20.1.10.441
4ph9IBPProstaglandin G/H synthase 21.14.99.10.441
1e94ANPATP-dependent protease ATPase subunit HslU/0.440
1hw5CMPcAMP-activated global transcriptional regulator CRP/0.440
1jpaANPEphrin type-B receptor 22.7.10.10.440
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.440
1u1f183Uridine phosphorylase2.4.2.30.440
1u54ACPActivated CDC42 kinase 1/0.440
1xelUPGUDP-glucose 4-epimerase5.1.3.20.440
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.440
2fxfACODiamine acetyltransferase 1/0.440
2igoFADPyranose 2-oxidase/0.440
2jn3JN3Fatty acid-binding protein, liver/0.440
2ojg19AMitogen-activated protein kinase 12.7.11.240.440
2rc3NADCBS domain/0.440
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
3hllI45Mitogen-activated protein kinase 14/0.440
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.440
3oqkS52Renin3.4.23.150.440
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.440
3v4tUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440
4a6nFADTetX family tetracycline inactivation enzyme/0.440
4awp99AHeat shock protein HSP 90-alpha/0.440
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4dfrMTXDihydrofolate reductase1.5.1.30.440
4fhi0S4Vitamin D3 receptor A/0.440
4fmqANPMitogen-activated protein kinase 12.7.11.240.440
4ifn12OKelch-like ECH-associated protein 1/0.440
4iteTEYVitamin D3 receptor/0.440
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.440
4lx9ACON-alpha-acetyltransferase2.3.10.440
4nxvGDPMitochondrial dynamics protein MID51/0.440
4oznATPAmmonium transporter/0.440
5bukFADFADH2-dependent halogenase/0.440