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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4wsqKSAAP2-associated protein kinase 12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4wsqKSAAP2-associated protein kinase 12.7.11.11.000
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.555
4hvi19STyrosine-protein kinase JAK32.7.10.20.543
1yvj4STTyrosine-protein kinase JAK32.7.10.20.521
4aqc88ATyrosine-protein kinase JAK2/0.521
3be9P04Casein kinase II subunit alpha2.7.11.10.519
4hge15VTyrosine-protein kinase JAK2/0.519
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.516
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.514
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.511
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.511
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.511
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.509
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.506
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.506
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.505
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.504
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.503
3sheI85MAP kinase-activated protein kinase 32.7.11.10.502
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.501
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.500
3gubGUBDeath-associated protein kinase 12.7.11.10.500
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.499
1xjdSTUProtein kinase C theta type2.7.11.130.498
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.498
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.498
3hx4ANPCalmodulin-domain protein kinase 1/0.497
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.496
5e8ySTUTGF-beta receptor type-22.7.11.300.496
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.495
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.495
3eljGS7Mitogen-activated protein kinase 82.7.11.240.494
4qnyANPMitogen activated protein kinase, putative/0.494
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.493
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.493
4gmy0X5Tyrosine-protein kinase JAK2/0.493
4o0wADNAurora kinase A2.7.11.10.493
4jboWPHAurora kinase A2.7.11.10.492
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.491
2q5g1FAPeroxisome proliferator-activated receptor delta/0.491
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.491
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.491
4jbqVX6Aurora kinase A2.7.11.10.491
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.490
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.490
4bgg844Activin receptor type-12.7.11.300.490
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.489
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.489
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.487
4btjADPTau-tubulin kinase 12.7.11.10.487
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.485
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.484
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.484
4hvh19RTyrosine-protein kinase JAK32.7.10.20.484
4jbpYPHAurora kinase A2.7.11.10.484
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.483
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.483
2excJNKMitogen-activated protein kinase 102.7.11.240.483
2w05FRTCyclin-dependent kinase 22.7.11.220.483
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.483
4btjATPTau-tubulin kinase 12.7.11.10.483
1h1s4SPCyclin-dependent kinase 22.7.11.220.482
2h96893Mitogen-activated protein kinase 82.7.11.240.482
2hog710Serine/threonine-protein kinase Chk12.7.11.10.482
2vu3LZECyclin-dependent kinase 22.7.11.220.482
3zewSTUEphrin type-B receptor 42.7.10.10.482
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.482
4jia1K3Tyrosine-protein kinase JAK2/0.482
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.481
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.481
5dt3ATPAurora kinase A2.7.11.10.481
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.480
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.480
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.480
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.480
3ggfGVDSerine/threonine-protein kinase 26/0.480
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.480
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.479
2j0m4STFocal adhesion kinase 12.7.10.20.479
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.479
3iok1P6Tyrosine-protein kinase JAK2/0.479
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.479
4k33ACPFibroblast growth factor receptor 32.7.10.10.479
4qmpDKISerine/threonine-protein kinase 242.7.11.10.479
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.478
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.478
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.478
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.478
2xa4AZ5Tyrosine-protein kinase JAK2/0.478
3ekwDR7Gag-Pol polyprotein3.4.23.160.478
3so9017Pol protein/0.478
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.478
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.477
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.477
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.477
3oom507Activin receptor type-12.7.11.300.477
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.477
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.477
4ux9ANPMitogen-activated protein kinase 82.7.11.240.477
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.476
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.476
4ez50RSCyclin-dependent kinase 62.7.11.220.476
2ckeIQUDeath-associated protein kinase 2/0.475
2p33J07Mitogen-activated protein kinase 102.7.11.240.475
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.475
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.475
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.475
2pvnP63Casein kinase II subunit alpha2.7.11.10.474
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.474
3ttjJBIMitogen-activated protein kinase 102.7.11.240.474
4anmWULCasein kinase II subunit alpha2.7.11.10.474
1eh4IC1Casein kinase I homolog 12.7.11.10.473
1eioGCHGastrotropin/0.473
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.473
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.473
3lpbNVBTyrosine-protein kinase JAK2/0.473
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.473
4hvg19QTyrosine-protein kinase JAK32.7.10.20.473
4i22IREEpidermal growth factor receptor2.7.10.10.473
1gih1PUCyclin-dependent kinase 22.7.11.220.472
1yb5NAPQuinone oxidoreductase1.6.5.50.472
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.472
2uzbC75Cyclin-dependent kinase 22.7.11.220.472
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.472
3r9hZ67Cyclin-dependent kinase 22.7.11.220.472
3vf7031Gag-Pol polyprotein3.4.23.160.472
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.472
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.472
4grb0XGCasein kinase II subunit alpha2.7.11.10.472
5cvfATPCasein kinase II subunit alpha2.7.11.10.472
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.471
4a6bQG8Gag-Pol polyprotein3.4.23.160.471
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.471
1kkq471Peroxisome proliferator-activated receptor alpha/0.470
2pvhP19Casein kinase II subunit alpha2.7.11.10.470
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.470
3jvy017Gag-Pol polyprotein3.4.23.160.470
1bygSTUTyrosine-protein kinase CSK/0.469
1g5sI17Cyclin-dependent kinase 22.7.11.220.469
2bpy3INGag-Pol polyprotein3.4.23.160.469
2f3kRO1Protease/0.469
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.469
3qtuX44Cyclin-dependent kinase 22.7.11.220.469
4aotGW8Serine/threonine-protein kinase 102.7.11.10.469
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.469
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.469
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.469
5dn3ATPAurora kinase A2.7.11.10.469
1bdrIM1Gag-Pol polyprotein3.4.23.160.468
1dawANPCasein kinase II subunit alpha2.7.11.10.468
2i4xKGQProtease/0.468
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.468
3r9dX6BCyclin-dependent kinase 22.7.11.220.468
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.468
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.468
4jqeANPCasein kinase II subunit alpha2.7.11.10.468
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.467
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.467
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3bu5ATPInsulin receptor2.7.10.10.467
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.467
4c58824Cyclin-G-associated kinase2.7.11.10.467
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.467
4i5cC5ITyrosine-protein kinase JAK1/0.467
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.467
5dpvSKEAurora kinase A2.7.11.10.467
1aq1STUCyclin-dependent kinase 22.7.11.220.466
1kzkJE2Gag-Pol polyprotein3.4.23.160.466
2eufLQQCyclin-dependent kinase 62.7.11.220.466
2iw84SPCyclin-dependent kinase 22.7.11.220.466
2vttLZDCyclin-dependent kinase 22.7.11.220.466
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.466
3gxlQIGTGF-beta receptor type-12.7.11.300.466
3t8oATPRhodopsin kinase/0.466
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.466
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.466
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.466
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.466
2uy0HV1Gag-Pol polyprotein3.4.23.160.465
3i60E86Mitogen-activated protein kinase 12.7.11.240.465
3l8p0CEAngiopoietin-1 receptor2.7.10.10.465
3s85LK0Gag-Pol polyprotein/0.465
3zep1NXTyrosine-protein kinase JAK32.7.10.20.465
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.465
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.465
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.465
1bai0Q4Gag-Pro polyprotein/0.464
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.464
3a62STURibosomal protein S6 kinase beta-12.7.11.10.464
3cgfJNFMitogen-activated protein kinase 102.7.11.240.464
3d1yROCGag-Pol polyprotein3.4.23.160.464
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.464
3rkb12ZCyclin-dependent kinase 22.7.11.220.464
3sa5A69Protease/0.464
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.464
4deeADPAurora kinase A2.7.11.10.464
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.464
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.464
4ysjADPCalmodulin-like domain protein kinase/0.464
5dr9SKEAurora kinase A2.7.11.10.464
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.463
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.463
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
3s1h56ZCyclin-dependent kinase 22.7.11.220.463
3uli1N3Cyclin-dependent kinase 22.7.11.220.463
3zh8C58Protein kinase C iota type2.7.11.130.463
4dgnLU2Casein kinase II subunit alpha2.7.11.10.463
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.463
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.463
4rvj478Protease/0.463
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.463
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.462
2x1nX1NCyclin-dependent kinase 22.7.11.220.462
3rak03ZCyclin-dependent kinase 22.7.11.220.462
3w18N13Aurora kinase A2.7.11.10.462
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4fv6E57Mitogen-activated protein kinase 12.7.11.240.462
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.462
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.462
5e8xSTUTGF-beta receptor type-12.7.11.300.462
1a8g2Z4Gag-Pol polyprotein3.4.23.160.461
1di8DTQCyclin-dependent kinase 22.7.11.220.461
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.461
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.461
2izsBRQCasein kinase I isoform gamma-32.7.11.10.461
2vv9IM9Cyclin-dependent kinase 22.7.11.220.461
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.461
3gw9VNILanosterol 14-alpha-demethylase/0.461
3lfnA27Cyclin-dependent kinase 22.7.11.220.461
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.461
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.461
4ivb1J5Tyrosine-protein kinase JAK1/0.461
4lopSB4Mitogen-activated protein kinase 14/0.461
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.461
5e92ANPTGF-beta receptor type-22.7.11.300.461
1k6pXN3Gag-Pol polyprotein3.4.23.160.460
1pxmCK5Cyclin-dependent kinase 22.7.11.220.460
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.460
2xrwANPMitogen-activated protein kinase 82.7.11.240.460
3bvb017Gag-Pol polyprotein3.4.23.160.460
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.460
4utdACPAurora kinase A2.7.11.10.460
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.460
1pmn984Mitogen-activated protein kinase 102.7.11.240.459
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.459
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.459
2q631UNGag-Pol polyprotein3.4.23.160.459
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.459
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.459
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.459
3linE13Protease/0.459
4djqM86Pol polyprotein/0.459
4e4m0NHTyrosine-protein kinase JAK2/0.459
4gk2L66Ephrin type-A receptor 32.7.10.10.459
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.459
1xuoLA1Integrin alpha-L/0.458
2b7aIZATyrosine-protein kinase JAK2/0.458
2fdd385Pol protein/0.458
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.458
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.458
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.458
3at4CCKCasein kinase II subunit alpha2.7.11.10.458
3hmm855TGF-beta receptor type-12.7.11.300.458
3saa77FProtease/0.458
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.458
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.458
4j95ACPFibroblast growth factor receptor 2/0.458
4xumIMNPeroxisome proliferator-activated receptor gamma/0.458
1fvv107Cyclin-dependent kinase 22.7.11.220.457
1n49RITGag-Pol polyprotein3.4.23.160.457
1u54ACPActivated CDC42 kinase 1/0.457
2q54MU1Protease/0.457
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.457
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.457
3ggxGGXGag-Pol polyprotein/0.457
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3lzv017Gag-Pol polyprotein3.4.23.160.457
3mtfA3FActivin receptor type-12.7.11.300.457
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.457
3oroAGSSerine/threonine protein kinase/0.457
4e6d0NUTyrosine-protein kinase JAK2/0.457
4ji91M3Tyrosine-protein kinase JAK2/0.457
1ivp1ZKGag-Pol polyprotein/0.456
2b60RITPol polyprotein/0.456
2qak1UNGag-Pol polyprotein3.4.23.160.456
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.456
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.456
3cyxROCGag-Pol polyprotein3.4.23.160.456
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.456
3s43478Protease/0.456
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.456
4c62XWWTyrosine-protein kinase JAK2/0.456
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.456
4hdfG52Gag-Pol polyprotein3.4.23.160.456
4hgt15GCasein kinase I isoform delta2.7.11.10.456
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.456
5dosATPAurora kinase A2.7.11.10.456
5e8wSTUTGF-beta receptor type-12.7.11.300.456
1oiuN76Cyclin-dependent kinase 22.7.11.220.455
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.455
1v9aSAHUncharacterized protein/0.455
2f8g017Gag-Pol polyprotein3.4.23.160.455
2hs2017Protease/0.455
2i4vDJRV-1 protease/0.455
2r5pMK1Gag-Pol polyprotein/0.455
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.455
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.455
3el9DR7Gag-Pol polyprotein3.4.23.160.455
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.455
4c57FEFCyclin-G-associated kinase2.7.11.10.455
4oauADP2-5A-dependent ribonuclease3.1.260.455
4ye3G04Gag-Pol polyprotein3.4.23.160.455
5drdATPAurora kinase A2.7.11.10.455
1h1r6CPCyclin-dependent kinase 22.7.11.220.454
1hiiC20Gag-Pol polyprotein/0.454
1idb0DOGag-Pol polyprotein/0.454
1msmJE2Gag-Pol polyprotein3.4.23.160.454
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.454
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.454
2zb3NDPProstaglandin reductase 21.3.1.480.454
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3ekp478Gag-Pol polyprotein3.4.23.160.454
3el1DR7Gag-Pol polyprotein3.4.23.160.454
3nwxKVSGag-Pol polyprotein3.4.23.160.454
3w8qAGSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.454
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.454
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.454
1k6tXN1Gag-Pol polyprotein3.4.23.160.453
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.453
2iw94SPCyclin-dependent kinase 22.7.11.220.453
2po7CHDFerrochelatase, mitochondrial4.99.1.10.453
2xneASHAurora kinase A2.7.11.10.453
3dckKVIProtease/0.453
3i99FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.453
3k5uPFQAurora kinase A2.7.11.10.453
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.453
3pwrROCGag-Pol polyprotein3.4.23.160.453
3rvg17PTyrosine-protein kinase JAK2/0.453
3zdu38RCyclin-dependent kinase-like 32.7.11.220.453
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.453
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.453
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.453
4qgiROCGag-Pol polyprotein3.4.23.160.453
1b6pPI7Gag-Pol polyprotein3.4.23.160.452
1ec3MS3Gag-Pol polyprotein3.4.23.160.452
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.452
1qvrANPChaperone protein ClpB/0.452
2pym1UNGag-Pol polyprotein3.4.23.160.452
2qi5MZ7Gag-Pol polyprotein/0.452
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.452
2xyeCXGGag-Pol polyprotein/0.452
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.452
3dcrKVSProtease/0.452
3ddqRRCCyclin-dependent kinase 22.7.11.220.452
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.452
3gu83GUDeath-associated protein kinase 12.7.11.10.452
3i7eDJRGag-Pol polyprotein/0.452
3s56ROCProtease/0.452
3sa9A68Protease/0.452
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.452
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.452
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.452
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.452
4dqc017Gag-Pol polyprotein/0.452
4dymIYZActivin receptor type-12.7.11.300.452
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.452
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.452
5dnrATPAurora kinase A2.7.11.10.452
1om1IQACasein kinase II subunit alpha2.7.11.10.451
1xddAAYIntegrin alpha-L/0.451
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.451
2bqvA1AProtease/0.451
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.451
2ijmADPFocal adhesion kinase 12.7.10.20.451
2in6839Wee1-like protein kinase2.7.10.20.451
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.451
3nwq2NCGag-Pol polyprotein3.4.23.160.451
3qaaG04Gag-Pol polyprotein3.4.23.160.451
4fkv61KCyclin-dependent kinase 22.7.11.220.451
4g3jVNTLanosterol 14-alpha-demethylase/0.451
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.451
4ic7ANPMitogen-activated protein kinase 72.7.11.240.451
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.451
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.451
4y8wSTRSteroid 21-hydroxylase/0.451
1bxoPP7Penicillopepsin-13.4.23.200.450
1g35AHFGag-Pol polyprotein3.4.23.160.450
1jklANPDeath-associated protein kinase 12.7.11.10.450
1pkdUCNCyclin-dependent kinase 22.7.11.220.450
1ppm0P1Penicillopepsin-13.4.23.200.450
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.450
1xl2189Gag-Pol polyprotein3.4.23.160.450
2p3c3TLProtease/0.450
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.450
2qi3MZ5Gag-Pol polyprotein/0.450
2upjU02Gag-Pol polyprotein3.4.23.160.450
2v7a627Tyrosine-protein kinase ABL12.7.10.20.450
2xmyCDKCyclin-dependent kinase 22.7.11.220.450
2xx91NFGlutamate receptor 2/0.450
2yn8STUEphrin type-B receptor 42.7.10.10.450
3kdcJZPGag-Pol polyprotein3.4.23.160.450
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.450
1difA85Gag-Pol polyprotein/0.449
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.449
1iziQ50Gag-Pol polyprotein3.4.23.160.449
1m2pHNACasein kinase II subunit alpha2.7.11.10.449
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.449
2bpz3INGag-Pol polyprotein3.4.23.160.449
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.449
2nmyROCProtease/0.449
2qi0MZ3Gag-Pol polyprotein/0.449
2r5q1UNGag-Pol polyprotein/0.449
2w1fL0FAurora kinase A2.7.11.10.449
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.449
2x6dX6DAurora kinase A2.7.11.10.449
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.449
3cgoJNOMitogen-activated protein kinase 102.7.11.240.449
3ekyDR7Gag-Pol polyprotein3.4.23.160.449
3gc8B45Mitogen-activated protein kinase 112.7.11.240.449
3lixE17Protease/0.449
3ogqAB1Pol polyprotein/0.449
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.449
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.449
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.449
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.449
1bdqIM1Gag-Pol polyprotein3.4.23.160.448
1e9hINRCyclin-dependent kinase 22.7.11.220.448
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.448
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.448
2qhcAB1Protease/0.448
2r43G3GGag-Pol polyprotein3.4.23.160.448
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.448
3a2oKNJGag-Pol polyprotein3.4.23.160.448
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.448
3kfs3TLGag-Pol polyprotein/0.448
3nynSGVG protein-coupled receptor kinase 62.7.11.160.448
3qp0NI8Gag-Pol polyprotein3.4.23.160.448
3vquO22Dual specificity protein kinase TTK2.7.12.10.448
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.448
4ivc1J6Tyrosine-protein kinase JAK1/0.448
4jr7GNPCasein kinase II subunit alpha2.7.11.10.448
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.448
4oavACP2-5A-dependent ribonuclease3.1.260.448
9hvp0E9Gag-Pol polyprotein/0.448
1cboFADCholesterol oxidase1.1.3.60.447
1hxbROCGag-Pol polyprotein3.4.23.160.447
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.447
1qbrXV6Gag-Pol polyprotein3.4.23.160.447
2avvMK1Gag-Pol polyprotein3.4.23.160.447
2b1pAIZMitogen-activated protein kinase 102.7.11.240.447
2nnpROCProtease/0.447
2p4yC03Peroxisome proliferator-activated receptor gamma/0.447
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.447
3kvxFMYMitogen-activated protein kinase 102.7.11.240.447
3lltANPProtein serine/threonine kinase-1/0.447
3nu9478Gag-Pol polyprotein3.4.23.160.447
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.447
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.447
1ec2BEJGag-Pol polyprotein3.4.23.160.446
1hpoUNIGag-Pol polyprotein3.4.23.160.446
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1k6cMK1Gag-Pol polyprotein3.4.23.160.446
1lp4ANPCasein kinase II subunit alpha2.7.11.10.446
2cen4AHProtease/0.446
2fleAIProtease/0.446
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.446
2uxpCLMHTH-type transcriptional regulator TtgR/0.446
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.446
3el51UNGag-Pol polyprotein/0.446
3hzc2NCProtease/0.446
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.446
3kddJZQGag-Pol polyprotein3.4.23.160.446
4bbe3O4Tyrosine-protein kinase JAK2/0.446
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.446
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.446
4iva1J5Tyrosine-protein kinase JAK2/0.446
4o0uADNAurora kinase A2.7.11.10.446
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1a9mU0EGag-Pol polyprotein/0.445
1bwsNDPGDP-L-fucose synthase/0.445
1hsgMK1Gag-Pol polyprotein/0.445
1hvsA77Gag-Pol polyprotein/0.445
1meuDMPGag-Pol polyprotein3.4.23.160.445
1sh9RITGag-Pol polyprotein3.4.23.160.445
1xl5190Gag-Pol polyprotein3.4.23.160.445
1zys199Serine/threonine-protein kinase Chk12.7.11.10.445
2pmoHMDProtein kinase 7/0.445
2q641UNGag-Pol polyprotein3.4.23.160.445
2xyfG40Gag-Pol polyprotein/0.445
3ekv478Gag-Pol polyprotein3.4.23.160.445
3el4ROCGag-Pol polyprotein3.4.23.160.445
3ndtROCGag-Pol polyprotein3.4.23.160.445
3oxxDR7Gag-Pol polyprotein3.4.23.160.445
3rmf20ZCyclin-dependent kinase 22.7.11.220.445
3sa6F71Protease/0.445
3ttiKBIMitogen-activated protein kinase 102.7.11.240.445
3zxtACPDeath-associated protein kinase 12.7.11.10.445
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.445
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.445
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
4j54G52Gag-Pol polyprotein3.4.23.160.445
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.445
5awmANPStress-activated protein kinase JNK2.7.11.240.445
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.444
1sguMK1Gag-Pol polyprotein3.4.23.160.444
1y0s331Peroxisome proliferator-activated receptor delta/0.444
2bpw1INGag-Pol polyprotein3.4.23.160.444
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.444
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.444
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.444
2idw017Protease/0.444
2om9AJAPeroxisome proliferator-activated receptor gamma/0.444
2pk6O33V-1 protease/0.444
2qhyMZ1Gag-Pol polyprotein/0.444
2xngA0HAurora kinase A2.7.11.10.444
3bi6396Wee1-like protein kinase2.7.10.20.444
3ecg065Gag-Pol polyprotein3.4.23.470.444
3kfr3TLGag-Pol polyprotein/0.444
3o9iA61Gag-Pol polyprotein/0.444
3uyt0CKCasein kinase I isoform delta2.7.11.10.444
4bcnT9NCyclin-dependent kinase 22.7.11.220.444
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4fyn0VETyrosine-protein kinase SYK2.7.10.20.444
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4loqSB4Mitogen-activated protein kinase 14/0.444
4xlvACPInsulin receptor2.7.10.10.444
1hviA77Protease/0.443
1hxwRITGag-Pol polyprotein/0.443
1mrwK57Gag-Pol polyprotein3.4.23.160.443
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.443
1wbmBLLPol protein/0.443
2bpv1INGag-Pol polyprotein3.4.23.160.443
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.443
2nnhREACytochrome P450 2C8/0.443
2psvMUVProtease/0.443
2pwcG3GGag-Pol polyprotein3.4.23.160.443
2qoqANPEphrin type-A receptor 32.7.10.10.443
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.443
2wkz5AHGag-Pol polyprotein/0.443
3abaFLICytochrome P450/0.443
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3eb0DRKUncharacterized protein/0.443
3ggaGGWGag-Pol polyprotein/0.443
3h0aD30Peroxisome proliferator-activated receptor gamma/0.443
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.443
3sa323XProtease/0.443
3t113T1Gag-Pol polyprotein3.4.23.160.443
4aguD15Cyclin-dependent kinase-like 1/0.443
4c4g7RODual specificity protein kinase TTK2.7.12.10.443
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.443
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.443
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.443
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.443
4ia3BIVVitamin D3 receptor A/0.443
4lfiGNPCasein kinase II subunit alpha2.7.11.10.443
4wkqIREEpidermal growth factor receptor2.7.10.10.443
1m2qMNXCasein kinase II subunit alpha2.7.11.10.442
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.442
1qbu846Gag-Pol polyprotein3.4.23.160.442
1rl8RITGag-Pol polyprotein3.4.23.160.442
1sbgIM1Gag-Pol polyprotein/0.442
2bb9AKCGag-Pol polyprotein3.4.23.160.442
2dwbANPAurora kinase A2.7.11.10.442
2r38G4GGag-Pol polyprotein3.4.23.160.442
2vx07X7Ephrin type-B receptor 42.7.10.10.442
2xikJ60Serine/threonine-protein kinase 252.7.11.10.442
2znq401Peroxisome proliferator-activated receptor delta/0.442
3at3ATKCasein kinase II subunit alpha2.7.11.10.442
3bheBZNGag-Pol polyprotein3.4.23.160.442
3dxjNE6DNA-directed RNA polymerase subunit beta/0.442
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.442
3jw2017Gag-Pol polyprotein3.4.23.160.442
3mxeK54Gag-Pol polyprotein3.4.23.160.442
3nu4478Gag-Pol polyprotein3.4.23.160.442
3nxe2NCProtease/0.442
3pwm017Gag-Pol polyprotein3.4.23.160.442
3r8lZ30Cyclin-dependent kinase 22.7.11.220.442
3rk708ZCyclin-dependent kinase 22.7.11.220.442
3t2kFADSulfide-quinone reductase/0.442
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.442
4c4f7CEDual specificity protein kinase TTK2.7.12.10.442
4djr0KJPol polyprotein/0.442
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.442
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.442
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
1jld0PPGag-Pol polyprotein/0.441
1k1u0Q4Gag-Pol polyprotein3.4.23.160.441
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.441
2p3a3TLPol protein/0.441
2p3d3TLProtease/0.441
2q59240Peroxisome proliferator-activated receptor gamma/0.441
2qi4MZ6Gag-Pol polyprotein/0.441
2qnqQN3Gag-Pol polyprotein3.4.23.160.441
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.441
2z54AB1Gag-Pol polyprotein3.4.23.160.441
3ddpRC8Cyclin-dependent kinase 22.7.11.220.441
3em6017Gag-Pol polyprotein3.4.23.160.441
3gu6ADPDeath-associated protein kinase 12.7.11.10.441
3rk507ZCyclin-dependent kinase 22.7.11.220.441
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.441
3slkNDPPolyketide synthase extender module 2/0.441
3tl9ROCGag-Pol polyprotein3.4.23.160.441
3tmz06XCytochrome P450 2B41.14.14.10.441
3ufnROCGag-Pol polyprotein/0.441
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.441
4acm7YGCyclin-dependent kinase 22.7.11.220.441
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4bgh3I6Cyclin-dependent kinase 22.7.11.220.441
4c4h7RODual specificity protein kinase TTK2.7.12.10.441
4eok4SPCyclin-dependent kinase 22.7.11.220.441
4fko20KCyclin-dependent kinase 22.7.11.220.441
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.441
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.441
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.441
5dr6SKEAurora kinase A2.7.11.10.441
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.440
1k6vXN2Gag-Pol polyprotein3.4.23.160.440
1oiyN41Cyclin-dependent kinase 22.7.11.220.440
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.440
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.440
2igoFADPyranose 2-oxidase/0.440
2qd8065Gag-Pol polyprotein3.4.23.160.440
2qi1MZ4Gag-Pol polyprotein/0.440
2r3tG4GGag-Pol polyprotein3.4.23.160.440
2vtqLZACyclin-dependent kinase 22.7.11.220.440
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.440
2xnbY8LCyclin-dependent kinase 22.7.11.220.440
2xvdAS6Ephrin type-B receptor 42.7.10.10.440
2yaaATPDeath-associated protein kinase 2/0.440
3gu5ANPDeath-associated protein kinase 12.7.11.10.440
3le62BZCyclin-dependent kinase 22.7.11.220.440
3oxv478Gag-Pol polyprotein3.4.23.160.440
3oxw017Gag-Pol polyprotein3.4.23.160.440
3r8vZ62Cyclin-dependent kinase 22.7.11.220.440
3s3r0IWCathepsin B-like peptidase (C01 family)/0.440
3tqhNDPQuinone oxidoreductase/0.440
3v3vMYUMitogen-activated protein kinase 82.7.11.240.440
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.440
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.440
3wmxNADNAD dependent epimerase/dehydratase/0.440
4djoMK5Pol polyprotein/0.440
4f081RSTyrosine-protein kinase JAK2/0.440
4fmqANPMitogen-activated protein kinase 12.7.11.240.440
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.440
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.440
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.440
4hgs15GCasein kinase I isoform gamma-32.7.11.10.440
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.440
4k4p3TLGag-Pol polyprotein/0.440
4qzuRTLRetinol-binding protein 2/0.440