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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4bx7B4FStreptavidin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
4bx7B4FStreptavidin/1.000
4gdaBTNStreptavidin/0.663
2izhBTNStreptavidin/0.662
1srgMHBStreptavidin/0.658
2rtfBTNStreptavidin/0.648
1lcwSHMStreptavidin/0.643
1i9hBNIStreptavidin/0.639
1sreHABStreptavidin/0.639
2rtqIMIStreptavidin/0.639
3ry2BTNStreptavidin/0.638
2rtoIMIStreptavidin/0.635
1sriDMBStreptavidin/0.634
4dneDTBStreptavidin/0.632
2fhnBNIAvidin-related protein 4/5/0.626
1mk5BTNStreptavidin/0.625
3wznBTNStreptavidin/0.625
1srfMTBStreptavidin/0.624
1stpBTNStreptavidin/0.622
2izgBTNStreptavidin/0.619
2rtdBTNStreptavidin/0.619
1df8BTNStreptavidin/0.618
1srhMOBStreptavidin/0.617
1srjNABStreptavidin/0.617
2rtgBTNStreptavidin/0.616
2rteBTNStreptavidin/0.610
2izlIMIStreptavidin/0.608
1rxhBNIStreptavidin/0.606
1luqBTNStreptavidin/0.605
2rtpIMIStreptavidin/0.605
1swtBTNStreptavidin/0.601
2izfBTNStreptavidin/0.597
2rtnIMIStreptavidin/0.597
4z28BTNHoefavidin/0.593
2y3fBTNStreptavidin/0.590
2rtrIMIStreptavidin/0.589
2iziBTNStreptavidin/0.587
1lczBH7Streptavidin/0.585
2aviBTNAvidin/0.581
1swpBTQStreptavidin/0.578
3wyqBTNStreptavidin/0.578
2rtmIMIStreptavidin/0.576
3t2wBTNAvidin/streptavidin/0.575
3rdqDTBStreptavidin/0.571
1swnBTNStreptavidin/0.570
1swrBTNStreptavidin/0.567
1swpBTNStreptavidin/0.566
4bcsBTNAvidin-related protein 4/5/0.565
1nqmBTNStreptavidin/0.564
1avdBTNAvidin/0.563
2izjBTNStreptavidin/0.563
2fhlBNIAvidin-related protein 4/5/0.562
2uz2BTNAvd protein/0.554
2zscBTNTamavidin2/0.544
1n43BTNStreptavidin/0.539
2c4iBTNAvidin/0.537
2rtiGLLStreptavidin/0.534
1sweBTNStreptavidin/0.529
1y52BTNAvidin-related protein 4/5/0.529
1n9mBTNStreptavidin/0.523
2uywBTNAvd protein/0.523
3ew2BTNHypothetical conserved protein/0.522
1nc9IMIStreptavidin/0.521
2izkGLLStreptavidin/0.513
1swdBTNStreptavidin/0.510
4gd9BTNStreptavidin/0.508
1ndjBTNStreptavidin/0.505
4bj8BTNAvidin/0.503
1mepBTNStreptavidin/0.501
4bb3KKAIsopenicillin N synthase1.21.3.10.501
3gwfFADCyclohexanone monooxygenase/0.497
4yvbBTNStreptavidin/0.495
4ap3FADSteroid monooxygenase/0.493
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.491
4mr61K0Bromodomain-containing protein 2/0.491
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.491
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.490
1nw6SFGModification methylase RsrI2.1.1.720.490
2zjwREFCasein kinase II subunit alpha2.7.11.10.489
3bw4FMNPutative 2-nitropropane dioxygenase/0.489
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.488
2zbaZBATrichothecene 3-O-acetyltransferase/0.487
2rtkGLLStreptavidin/0.484
2xveFADPutative flavin-containing monooxygenase/0.484
3pqbVGPPutative oxidoreductase/0.483
3wypBSOStreptavidin/0.483
2vbpVB1Isopenicillin N synthase1.21.3.10.481
2y60M8FIsopenicillin N synthase1.21.3.10.480
1hb1OCVIsopenicillin N synthase1.21.3.10.479
1obnASVIsopenicillin N synthase1.21.3.10.479
3vf60H6Glucokinase2.7.1.20.479
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.479
5iqdGNPBifunctional AAC/APH2.3.10.479
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.478
2x9dITCTetracycline repressor protein class D/0.478
3jpuTY4Transcriptional activator protein LasR/0.478
4ure1PSCyclohexanol dehydrogenase/0.478
3bw2FMNPutative 2-nitropropane dioxygenase/0.477
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.477
1pq944BOxysterols receptor LXR-beta/0.476
1trgCB3Thymidylate synthase/0.476
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.476
3vgwNVZAvidin/0.476
4jlj1NMDeoxycytidine kinase2.7.1.740.476
1zdwFLVPrenyltransferase/0.475
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.475
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.475
1phhFADp-hydroxybenzoate hydroxylase/0.474
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.474
3vtdTKDVitamin D3 receptor/0.474
3qakUKAAdenosine receptor A2a/0.474
2xlsFADPutative flavin-containing monooxygenase/0.473
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.473
1culFOKAdenylate cyclase type 2/0.472
1culFOKAdenylate cyclase type 5/0.472
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.472
1qiqACCIsopenicillin N synthase1.21.3.10.472
3biy01KHistone acetyltransferase p300/0.472
1s3uTQDDihydrofolate reductase1.5.1.30.471
2jgsBTNAvidin/0.471
3c3xNAPEugenol synthase 11.1.1.3180.471
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.471
1nw5SAMModification methylase RsrI2.1.1.720.470
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.470
2ftoCB3Thymidylate synthase/0.470
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.470
4aosFADSteroid monooxygenase/0.470
4twnB96Ephrin type-A receptor 32.7.10.10.470
5eccNAPDehydrofolate reductase type I/0.470
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.469
2rs1W84Genome polyprotein/0.469
2xlpFADPutative flavin-containing monooxygenase/0.469
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.469
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.469
1ppjANYCytochrome b/0.468
3vhhVHHAvidin/0.468
4g6hNAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.468
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2r0pK2CPutative FAD-monooxygenase/0.467
2w6mOA1Biotin carboxylase6.3.4.140.467
3juhANPCasein kinase II subunit alpha2.7.11.10.467
4pnmNU1Tankyrase-22.4.2.300.467
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.467
1afeALZProthrombin3.4.21.50.466
1m78NDPDihydrofolate reductase1.5.1.30.466
1x8lOXRRetinol dehydratase/0.466
2fjbSFDAdenylylsulfate reductase, subunit A (AprA)/0.466
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
2rtlIMIStreptavidin/0.466
3q44D50M1 family aminopeptidase3.4.110.466
4dymIYZActivin receptor type-12.7.11.300.466
4ggzBTNBll1558 protein/0.466
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.466
2fznFADBifunctional protein PutA1.5.5.20.465
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.465
2p5yNADUDP-glucose 4-epimerase/0.465
4dc0NDPPutative ketoacyl reductase1.3.10.465
4y9lFADAcyl-CoA dehydrogenase family member 11/0.465
1r2jFADFkbI/0.464
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.464
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.464
3fhxPLPPyridoxal kinase2.7.1.350.464
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.300.464
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.464
4m9aFDAAcyl-CoA dehydrogenase/0.464
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.463
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.463
1d6w00RProthrombin3.4.21.50.462
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.462
1jnrFADAdenylylsulfate reductase, subunit A (AprA)/0.462
1jtuLYBThymidylate synthase/0.462
1kceCB3Thymidylate synthase/0.462
1lkeDOGBilin-binding protein/0.462
1wsvTHHAminomethyltransferase, mitochondrial/0.462
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.462
3d4bDZDNAD-dependent protein deacetylase/0.462
3tm5SFGUncharacterized protein/0.462
4c1fX8ZMetallo-beta-lactamase type 2/0.462
4ez8DHFThymidylate synthase2.1.1.450.462
4i8vBHFCytochrome P450 1A11.14.14.10.462
4nieNBHNuclear receptor ROR-gamma/0.462
4yddMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.462
1gheACOAcetyltransferase2.3.10.461
1h36R88Squalene--hopene cyclase4.2.1.1290.461
1oc1ASVIsopenicillin N synthase1.21.3.10.461
2j9lATPH(+)/Cl(-) exchange transporter 5/0.461
3zoiM2WIsopenicillin N synthase1.21.3.10.461
4a81DXCMajor pollen allergen Bet v 1-A/0.461
4a83DXCMajor pollen allergen Bet v 1-A/0.461
4orkGDPBifunctional AAC/APH2.3.10.461
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.460
1kziTHGThymidylate synthase/0.460
3bg7FADPyranose 2-oxidase/0.460
3f0rTSNHistone deacetylase 83.5.1.980.460
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.460
3nr4PYVAbscisic acid receptor PYL2/0.460
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.460
4fqsLYAThymidylate synthase ThyA/0.460
4okx198Androgen receptor/0.460
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.460
2kceD16Thymidylate synthase/0.459
2zpaADPtRNA(Met) cytidine acetyltransferase TmcA/0.459
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.459
4c6zTLE3-oxoacyl-ACP synthase/0.459
4psbGA3Cytokinin-specific binding protein/0.459
5iqeGNPBifunctional AAC/APH2.3.10.459
4ldeP0GBeta-2 adrenergic receptor/0.459
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.458
2a5c8DAAvidin/0.458
2acwUPGGlycosyltransferase/0.458
2hvdADPNucleoside diphosphate kinase A2.7.4.60.458
2w9hTOPDihydrofolate reductase1.5.1.30.458
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.458
3flwFLWMitogen-activated protein kinase 14/0.458
3g7jGTXGlutathione transferase GST1-4/0.458
3uk6ADPRuvB-like 23.6.4.120.458
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.458
4kwhNAPReductase homolog/0.458
4pd6URINucleoside permease/0.458
1cjkFOKAdenylate cyclase type 2/0.457
1cjkFOKAdenylate cyclase type 5/0.457
1dnaCB3Thymidylate synthase/0.457
1qknRALEstrogen receptor beta/0.457
1uydPU8Heat shock protein HSP 90-alpha/0.457
2xvfFADPutative flavin-containing monooxygenase/0.457
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.457
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.457
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.457
4dpy2P0Mevalonate diphosphate decarboxylase/0.457
1gky5GPGuanylate kinase2.7.4.80.456
2flhZEACytokinin-specific binding protein/0.456
2wo7ASVIsopenicillin N synthase1.21.3.10.456
3p9tTCLRepressor/0.456
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4gevCB3Thymidylate synthase/0.456
5bt42LOBromodomain-containing protein 4/0.456
1ay0TPPTransketolase 12.2.1.10.455
1dr3HBIDihydrofolate reductase1.5.1.30.455
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2q7vFADThioredoxin reductase/0.455
2xtbKRMAdenosine kinase, putative/0.455
3arvSAUChitinase A/0.455
3d7zGK5Mitogen-activated protein kinase 14/0.455
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.455
4aoxFADSteroid monooxygenase/0.455
4xrgNADHomospermidine synthase2.5.1.440.455
5iqgGDPBifunctional AAC/APH2.3.10.455
1axwMTXThymidylate synthase/0.454
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
2iviACWIsopenicillin N synthase1.21.3.10.454
2tscCB3Thymidylate synthase/0.454
2wotZZGTGF-beta receptor type-12.7.11.300.454
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.454
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.454
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.454
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.454
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.454
1bk0ACVIsopenicillin N synthase1.21.3.10.453
1ci7UMPThymidylate synthase2.1.1.450.453
1efvFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.453
1kt6RTLRetinol-binding protein 4/0.453
1p8dCO1Oxysterols receptor LXR-beta/0.453
1psa0ZLPepsin A3.4.23.10.453
2bn4FADNADPH--cytochrome P450 reductase/0.453
2bu9HFVIsopenicillin N synthase1.21.3.10.453
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
2oegUPGUDP-glucose pyrophosphorylase/0.453
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.453
3r0tFU9Casein kinase II subunit alpha2.7.11.10.453
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.453
3zkuHCVIsopenicillin N synthase1.21.3.10.453
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.453
4jlm1NNDeoxycytidine kinase2.7.1.740.453
4kxl6C62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.453
4n3l2FNProthrombin3.4.21.50.453
4rtjSFGDNA adenine methylase2.1.1.720.453
1blzACVIsopenicillin N synthase1.21.3.10.452
1f4fTP3Thymidylate synthase/0.452
1hb3SCVIsopenicillin N synthase1.21.3.10.452
1j9zFADNADPH--cytochrome P450 reductase/0.452
1nzq162Prothrombin3.4.21.50.452
1pqc444Oxysterols receptor LXR-beta/0.452
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.452
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.452
2tohHBITyrosine 3-monooxygenase1.14.16.20.452
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.452
3a1l2CCCytochrome P450/0.452
3copADPGlycogen synthase2.4.1.210.452
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.452
3up3XCAaceDAF-12/0.452
3vi7CBDHematopoietic prostaglandin D synthase/0.452
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.452
4phlPILPhosphodiesterase/0.452
1cjtFOKAdenylate cyclase type 2/0.451
1cjtFOKAdenylate cyclase type 5/0.451
1jpaANPEphrin type-B receptor 22.7.10.10.451
1ly4COQDihydrofolate reductase1.5.1.30.451
1nc1MTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.451
1tllFADNitric oxide synthase, brain1.14.13.390.451
1uyiPUZHeat shock protein HSP 90-alpha/0.451
2xlrFADPutative flavin-containing monooxygenase/0.451
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.451
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3qlrNDPDihydrofolate reductase1.5.1.30.451
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
3v3vMYUMitogen-activated protein kinase 82.7.11.240.451
3zkyWT4Isopenicillin N synthase1.21.3.10.451
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.451
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.451
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.451
1cqp803Integrin alpha-L/0.450
1ia4TQ6Dihydrofolate reductase1.5.1.30.450
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.450
1zgi382Prothrombin3.4.21.50.450
2fszOHTEstrogen receptor beta/0.450
2g97DGBNicotinamide phosphoribosyltransferase2.4.2.120.450
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.450
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
2pg0FADAcyl-CoA dehydrogenase/0.450
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.450
3ibdCPZCytochrome P450 2B61.14.130.450
3r9hZ67Cyclin-dependent kinase 22.7.11.220.450
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4j6cSTRCytochrome P450 monooxygenase/0.450
4ryvZEAProtein LlR18A/0.450
4xqcNADHomospermidine synthase2.5.1.440.450
3sn6P0GBeta-2 adrenergic receptor/0.450
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.449
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.449
1lf3EH5Plasmepsin-23.4.23.390.449
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
1y0s331Peroxisome proliferator-activated receptor delta/0.449
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.449
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.449
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
3bl7DD1m7GpppX diphosphatase3.6.1.590.449
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.449
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.449
3h3sH15Collagen type IV alpha-3-binding protein/0.449
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.449
3vrwYS5Vitamin D3 receptor/0.449
5iqaGNPBifunctional AAC/APH2.3.10.449
5k2cZMAAdenosine receptor A2a/0.449
1d9i00PProthrombin3.4.21.50.448
1kzjCB3Thymidylate synthase/0.448
1mvtDTMDihydrofolate reductase1.5.1.30.448
1qjfACSIsopenicillin N synthase1.21.3.10.448
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.448
1x1cSAHC-20 methyltransferase/0.448
1ypkCCRProthrombin3.4.21.50.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2vbdV10Isopenicillin N synthase1.21.3.10.448
2vcmM11Isopenicillin N synthase1.21.3.10.448
2vo4GTB2,4-D inducible glutathione S-transferase/0.448
4j6dTESCytochrome P450 monooxygenase/0.448
4jq4IMNAldo-keto reductase family 1 member C2/0.448
5bylGCPBifunctional AAC/APH2.3.10.448
5iqiGNPBifunctional AAC/APH2.3.10.448
5g53NECAdenosine receptor A2a/0.448
1fmjRTLRetinol dehydratase/0.447
1pd9CO4Dihydrofolate reductase1.5.1.30.447
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.447
2q9fC3SCholesterol 24-hydroxylase/0.447
3biu10UProthrombin3.4.21.50.447
3fcjFADNitroalkane oxidase1.7.3.10.447
3lu8IQXSerum albumin/0.447
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.447
3p1799PProthrombin3.4.21.50.447
3p9kCIYCaffeic acid O-methyltransferase/0.447
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.447
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4h9506UDihydrofolate reductase1.5.1.30.447
4imfSI3N-acetylneuraminate lyase/0.447
4mv8ACPBiotin carboxylase6.3.4.140.447
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.447
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.447
5k2dZMAAdenosine receptor A2a/0.447
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.446
1cjvFOKAdenylate cyclase type 2/0.446
1cjvFOKAdenylate cyclase type 5/0.446
1o5rFR9Adenosine deaminase3.5.4.40.446
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
1zoyUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.446
1zoyUQ1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial/0.446
2v13C40Renin3.4.23.150.446
3gkjHC3Niemann-Pick C1 protein/0.446
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
3p62FMNPentaerythritol tetranitrate reductase/0.446
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
3ruvANPChaperonin/0.446
4c02TAKActivin receptor type-12.7.11.300.446
4h5tADPHeat shock cognate 71 kDa protein/0.446
4ib4ERM5-hydroxytryptamine receptor 2B/0.446
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.446
4nmbFADBifunctional protein PutA/0.446
4pztSOPHistone acetyltransferase p300/0.446
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.446
4wudANPDNA gyrase subunit B/0.446
4xd1T3QQdtf/0.446
5d1bTSNHistone deacetylase 83.5.1.980.446
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.446
5uviZMAAdenosine receptor A2a/0.446
4s0vSUVOrexin receptor type 2/0.446
1eioGCHGastrotropin/0.445
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1fvpFMANon-fluorescent flavoprotein/0.445
1jwtBLIProthrombin3.4.21.50.445
1kt3RTLRetinol-binding protein 4/0.445
1nhkCMPNucleoside diphosphate kinase2.7.4.60.445
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.445
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.445
1s9dAFBCytohesin-2/0.445
1s9dAFBADP-ribosylation factor 1/0.445
1tj1FADBifunctional protein PutA1.5.5.20.445
2h55DZ8Heat shock protein HSP 90-alpha/0.445
2hl2SSAThreonine--tRNA ligase6.1.1.30.445
2vf0F89Thymidylate synthase/0.445
3bi6396Wee1-like protein kinase2.7.10.20.445
3fu9KIBLaccase-11.10.3.20.445
3fywXCFDihydrofolate reductase1.5.1.30.445
3mb714ICasein kinase II subunit alpha2.7.11.10.445
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.445
4bfvZVVPantothenate kinase2.7.1.330.445
4bquCLRJapanin/0.445
4c72TLG3-oxoacyl-ACP synthase/0.445
4ejmNAPPutative zinc-binding dehydrogenase/0.445
4hy6FJ1Heat shock protein HSP 90-alpha/0.445
4ntcFADThioredoxin reductase gliT/0.445
1booSAHModification methylase PvuII2.1.1.1130.444
1bsvNDPGDP-L-fucose synthase/0.444
1zprCB3Thymidylate synthase/0.444
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
2ow9SP6Collagenase 33.4.240.444
2xszATPRuvB-like 23.6.4.120.444
2y6fM9FIsopenicillin N synthase1.21.3.10.444
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
3oqkS52Renin3.4.23.150.444
3tk3CPZCytochrome P450 2B41.14.14.10.444
3v76FDAUncharacterized protein/0.444
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.444
4d0lGSPRas-related protein Rab-11A/0.444
4g1z0VPVitamin D3 receptor A/0.444
4rtnSAHDNA adenine methylase2.1.1.720.444
4ruoBIVVitamin D3 receptor A/0.444
4uofDATNucleoside diphosphate kinase/0.444
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.444
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.444
5hs1VORLanosterol 14-alpha demethylase/0.444
5kghACOPredicted acetyltransferase/0.444
8catNDPCatalase1.11.1.60.444
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.443
1nm6L86Prothrombin3.4.21.50.443
1qf5RPLAdenylosuccinate synthetase/0.443
1r8qAFBCytohesin-2/0.443
1r8qAFBADP-ribosylation factor 1/0.443
1thnADPAnti-sigma F factor/0.443
1tysDHFThymidylate synthase/0.443
2a94AP0L-lactate dehydrogenase1.1.1.270.443
2ociTYCValacyclovir hydrolase3.10.443
2po7CHDFerrochelatase, mitochondrial4.99.1.10.443
2qo9ANPEphrin type-A receptor 32.7.10.10.443
2rqfJH3Hemolymph juvenile hormone binding protein/0.443
2wecPP5Penicillopepsin-13.4.23.200.443
2xvhFADPutative flavin-containing monooxygenase/0.443
3aw9NADNAD-dependent epimerase/dehydratase/0.443
3drcMTXDihydrofolate reductase1.5.1.30.443
3ielU5PRibonuclease TTHA02523.10.443
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.443
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.443
3tq8TOPDihydrofolate reductase/0.443
3w8wFADPutative FAD-dependent oxygenase EncM/0.443
3zeiAWHO-acetylserine sulfhydrylase/0.443
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.443
4dbs0HVAldo-keto reductase family 1 member C3/0.443
4dieC5PCytidylate kinase/0.443
4g210VPVitamin D3 receptor A/0.443
4g8bHL6Alpha/beta hydrolase fold protein/0.443
4j6bPLOCytochrome P450 monooxygenase/0.443
4l5b1UXDeoxycytidine kinase2.7.1.740.443
4uugPXGBranched-chain amino acid aminotransferase, putative/0.443
5iqbGNPBifunctional AAC/APH2.3.10.443
5iw5NMNNADH pyrophosphatase/0.443
6ctsCICCitrate synthase, mitochondrial2.3.3.10.443
4k5y1Q5Corticotropin-releasing factor receptor 1/0.443
1cdeGARPhosphoribosylglycinamide formyltransferase/0.442
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.442
1dr2TAPDihydrofolate reductase1.5.1.30.442
1dr3TAPDihydrofolate reductase1.5.1.30.442
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.442
1n0uSO1Elongation factor 2/0.442
1osvCHCBile acid receptor/0.442
1ot7CHCBile acid receptor/0.442
1q23FUAChloramphenicol acetyltransferase2.3.1.280.442
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.442
2cy2ACOProbable acetyltransferase/0.442
2dvlFADAcyl-CoA dehydrogenase/0.442
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2g1pSAHDNA adenine methylase2.1.1.720.442
2hamC33Vitamin D3 receptor/0.442
2j6xFMNLactate oxidase/0.442
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2qmyFADRibosyldihydronicotinamide dehydrogenase [quinone]/0.442
2rkvZBATrichothecene 3-O-acetyltransferase/0.442
2w4qCBWProstaglandin reductase 21.3.1.480.442
2zhf49UProthrombin3.4.21.50.442
3bhrTHGThymidylate synthase/0.442
3cobADPKinesin heavy chain-like protein/0.442
3d84NDPDihydrofolate reductase1.5.1.30.442
3ez2ADPPlasmid partition protein A/0.442
3oqfS51Renin3.4.23.150.442
3qofGDPAtlastin-13.6.50.442
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.442
4avlTMPPolymerase acidic protein/0.442
4b1iA8PPoly(ADP-ribose) glycohydrolase3.2.1.1430.442
4gbeSAHDNA adenine methylase2.1.1.720.442
4hdrDMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase/0.442
4hdrDMDArsB/0.442
4j3mAJ8Tankyrase-22.4.2.300.442
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.442
4rtmSAMDNA adenine methylase2.1.1.720.442
4rtsSAMDNA adenine methylase2.1.1.720.442
4ys22BAUncharacterized protein/0.442
5cb3APRO-acetyl-ADP-ribose deacetylase/0.442
5iubCLRAdenosine receptor A2a/0.442
1ia1NDPDihydrofolate reductase1.5.1.30.441
1mrqSTRAldo-keto reductase family 1 member C1/0.441
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1rd4L08Integrin alpha-L/0.441
1re0AFBADP-ribosylation factor 1/0.441
1re0AFBARF guanine-nucleotide exchange factor 1/0.441
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.441
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2bf7HBIPteridine reductase 11.5.1.330.441
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.441
2idkC2FGlycine N-methyltransferase2.1.1.200.441
2x6o2TCTetracycline repressor protein class D/0.441
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.441
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.441
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.441
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.441
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.441
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.441
4a84DXCMajor pollen allergen Bet v 1-A/0.441
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4gh5NADShort-chain dehydrogenase/reductase SDR/0.441
4knzCB3Thymidylate synthase/0.441
4rtpSAMDNA adenine methylase2.1.1.720.441
5cb5APRO-acetyl-ADP-ribose deacetylase/0.441
5emhNAPIridoid synthase1.3.1.990.441
5epoTUD7-alpha-hydroxysteroid deydrogenase/0.441
5dhhDGWNociceptin receptor/0.441
1c3eGARPhosphoribosylglycinamide formyltransferase/0.440
1c7oPPGHemolysin/0.440
1db1VDXVitamin D3 receptor/0.440
1hfqMOTDihydrofolate reductase1.5.1.30.440
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.440
1lhvNOGSex hormone-binding globulin/0.440
1mvsDTMDihydrofolate reductase1.5.1.30.440
1nbiSAMGlycine N-methyltransferase2.1.1.200.440
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1tsxUMPThymidylate synthase/0.440
1uzwCDHIsopenicillin N synthase1.21.3.10.440
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.440
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.440
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2q4wFADCytokinin dehydrogenase 71.5.99.120.440
2qw8NAPEugenol synthase 11.1.1.3180.440
2rr1W8RGenome polyprotein/0.440
3aosJH2Hemolymph juvenile hormone binding protein/0.440
3c1kT15Prothrombin3.4.21.50.440
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3iaeD7KBenzaldehyde lyase/0.440
3o6o94MHeat shock protein 83/0.440
3owuEQUSteroid Delta-isomerase5.3.3.10.440
3w5q3KLVitamin D3 receptor/0.440
3wdsNADNADH-dependent quinuclidinone reductase/0.440
4b1rITCTetracycline repressor protein class D/0.440
4hni16WCasein kinase I isoform epsilon2.7.11.10.440
4qa2SHHHistone deacetylase 83.5.1.980.440
4rrgA3TThreonine--tRNA ligase6.1.1.30.440
4rtqSAHDNA adenine methylase2.1.1.720.440
4wkbTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.440
7catNDPCatalase1.11.1.60.440