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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3zewSTUEphrin type-B receptor 42.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3zewSTUEphrin type-B receptor 42.7.10.11.000
2yn8STUEphrin type-B receptor 42.7.10.10.573
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.568
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.567
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.554
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.541
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.537
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.535
4y93746Tyrosine-protein kinase/0.535
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.530
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.527
2j0lANPFocal adhesion kinase 12.7.10.20.526
2j0m4STFocal adhesion kinase 12.7.10.20.526
4gk4L90Ephrin type-A receptor 32.7.10.10.525
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.524
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.524
4jia1K3Tyrosine-protein kinase JAK2/0.524
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.522
2qoqANPEphrin type-A receptor 32.7.10.10.521
2henADPEphrin type-B receptor 22.7.10.10.520
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.520
1bygSTUTyrosine-protein kinase CSK/0.517
4gk3L87Ephrin type-A receptor 32.7.10.10.517
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.515
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.515
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.514
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.513
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.512
2ijmADPFocal adhesion kinase 12.7.10.20.512
4gk2L66Ephrin type-A receptor 32.7.10.10.512
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.509
1u54ACPActivated CDC42 kinase 1/0.505
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.505
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.504
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.503
1yvj4STTyrosine-protein kinase JAK32.7.10.20.503
2x9fX9FEphrin type-B receptor 42.7.10.10.503
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.503
2hk51BMTyrosine-protein kinase HCK2.7.10.20.502
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.502
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.502
2qo7ANPEphrin type-A receptor 32.7.10.10.501
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.501
4y95746Tyrosine-protein kinase/0.500
3zh8C58Protein kinase C iota type2.7.11.130.499
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.499
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.498
4j98ACPFibroblast growth factor receptor 2/0.498
4e4m0NHTyrosine-protein kinase JAK2/0.497
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.497
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.496
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.496
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.496
4hvi19STyrosine-protein kinase JAK32.7.10.20.496
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.495
5e8wSTUTGF-beta receptor type-12.7.11.300.495
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.494
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.494
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.494
4gmy0X5Tyrosine-protein kinase JAK2/0.494
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.493
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.493
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.493
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.493
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.492
1aq1STUCyclin-dependent kinase 22.7.11.220.491
1pkdUCNCyclin-dependent kinase 22.7.11.220.491
4j97ACPFibroblast growth factor receptor 2/0.491
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.490
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.490
4hvh19RTyrosine-protein kinase JAK32.7.10.20.490
3i60E86Mitogen-activated protein kinase 12.7.11.240.489
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.489
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.489
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.489
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.488
5e8ySTUTGF-beta receptor type-22.7.11.300.488
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.487
2xyuQ9GEphrin type-A receptor 42.7.10.10.487
3gxlQIGTGF-beta receptor type-12.7.11.300.487
2of2547Tyrosine-protein kinase Lck2.7.10.20.486
3ac1KZITyrosine-protein kinase Lck2.7.10.20.486
4bcmT7ZCyclin-dependent kinase 22.7.11.220.486
4nka2K7Fibroblast growth factor receptor 1/0.486
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.485
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.485
5e8xSTUTGF-beta receptor type-12.7.11.300.485
1mqbANPEphrin type-A receptor 22.7.10.10.484
2qo9ANPEphrin type-A receptor 32.7.10.10.484
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.484
3at4CCKCasein kinase II subunit alpha2.7.11.10.484
4c62XWWTyrosine-protein kinase JAK2/0.484
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.484
1zrzBI1Protein kinase C iota type2.7.11.130.483
2i40BLZCyclin-dependent kinase 22.7.11.220.483
2vu3LZECyclin-dependent kinase 22.7.11.220.483
2xvdAS6Ephrin type-B receptor 42.7.10.10.483
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.483
2hog710Serine/threonine-protein kinase Chk12.7.11.10.482
2of4979Tyrosine-protein kinase Lck2.7.10.20.482
3be9P04Casein kinase II subunit alpha2.7.11.10.482
3d7tSTUTyrosine-protein kinase CSK/0.482
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.482
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.482
4riyADPEpidermal growth factor receptor2.7.10.10.482
2x6dX6DAurora kinase A2.7.11.10.481
3gubGUBDeath-associated protein kinase 12.7.11.10.481
3t8oATPRhodopsin kinase/0.481
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.480
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.480
4hgs15GCasein kinase I isoform gamma-32.7.11.10.480
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.479
1u4dDBQActivated CDC42 kinase 1/0.478
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.478
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.478
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.478
4aqc88ATyrosine-protein kinase JAK2/0.478
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.477
3vjoANPEpidermal growth factor receptor2.7.10.10.477
4ez50RSCyclin-dependent kinase 62.7.11.220.477
4hvg19QTyrosine-protein kinase JAK32.7.10.20.477
1xjdSTUProtein kinase C theta type2.7.11.130.476
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.476
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.476
3c4xATPRhodopsin kinase/0.476
4bb432WEphrin type-B receptor 42.7.10.10.476
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.476
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.476
1jpaANPEphrin type-B receptor 22.7.10.10.475
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.475
4erwSTUCyclin-dependent kinase 22.7.11.220.475
4fyn0VETyrosine-protein kinase SYK2.7.10.20.475
4j95ACPFibroblast growth factor receptor 2/0.475
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.474
2v7a627Tyrosine-protein kinase ABL12.7.10.20.474
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.474
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.473
2in6839Wee1-like protein kinase2.7.10.20.473
2itqITQEpidermal growth factor receptor2.7.10.10.473
2vwx7X4Ephrin type-B receptor 42.7.10.10.473
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.473
3uvqFS8Mitogen-activated protein kinase 14/0.472
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.472
4j99ACPFibroblast growth factor receptor 2/0.472
4jq8KJ8Epidermal growth factor receptor2.7.10.10.472
4qmySTUSerine/threonine-protein kinase 242.7.11.10.472
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.471
2qocANPEphrin type-A receptor 32.7.10.10.471
2z2w770Wee1-like protein kinase2.7.10.20.471
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.471
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.471
4jqeANPCasein kinase II subunit alpha2.7.11.10.471
5dosATPAurora kinase A2.7.11.10.471
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.470
4eooATPCyclin-dependent kinase 22.7.11.220.470
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.470
1finATPCyclin-dependent kinase 22.7.11.220.469
1g5sI17Cyclin-dependent kinase 22.7.11.220.469
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.469
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.469
2pvnP63Casein kinase II subunit alpha2.7.11.10.469
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.469
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.469
3uli1N3Cyclin-dependent kinase 22.7.11.220.469
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.469
2xngA0HAurora kinase A2.7.11.10.468
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.468
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.468
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.467
2ijmATPFocal adhesion kinase 12.7.10.20.467
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.467
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.467
4anmWULCasein kinase II subunit alpha2.7.11.10.467
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.467
3zep1NXTyrosine-protein kinase JAK32.7.10.20.466
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.466
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.466
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.466
5dnrATPAurora kinase A2.7.11.10.466
2pvmP29Casein kinase II subunit alpha2.7.11.10.465
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.465
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.465
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.465
5av2KMPDeath-associated protein kinase 12.7.11.10.465
2j0j4STFocal adhesion kinase 12.7.10.20.464
2vx17X8Ephrin type-B receptor 42.7.10.10.464
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.464
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.464
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.464
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.464
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.464
1e9hINRCyclin-dependent kinase 22.7.11.220.463
1m2pHNACasein kinase II subunit alpha2.7.11.10.463
1x8b824Wee1-like protein kinase2.7.10.20.463
4ji91M3Tyrosine-protein kinase JAK2/0.463
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.462
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.462
2itnANPEpidermal growth factor receptor2.7.10.10.462
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.462
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.462
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.462
4f640S8Fibroblast growth factor receptor 1/0.462
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.462
4fv6E57Mitogen-activated protein kinase 12.7.11.240.462
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.461
1eh4IC1Casein kinase I homolog 12.7.11.10.461
3biz61EWee1-like protein kinase2.7.10.20.461
4c61LMMTyrosine-protein kinase JAK2/0.461
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.461
4qmlANPSerine/threonine-protein kinase 242.7.11.10.461
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.460
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.460
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.460
2io6330Wee1-like protein kinase2.7.10.20.460
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.460
3a62STURibosomal protein S6 kinase beta-12.7.11.10.460
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.459
2j7t274Serine/threonine-protein kinase 102.7.11.10.459
2vwu7X1Ephrin type-B receptor 42.7.10.10.459
3hmm855TGF-beta receptor type-12.7.11.300.459
3tnwF18Cyclin-dependent kinase 22.7.11.220.459
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.459
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.459
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.459
2pwlACPFibroblast growth factor receptor 2/0.458
2vww7X2Ephrin type-B receptor 42.7.10.10.458
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.458
3lltANPProtein serine/threonine kinase-1/0.458
3lpbNVBTyrosine-protein kinase JAK2/0.458
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.458
4bbe3O4Tyrosine-protein kinase JAK2/0.458
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.458
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.457
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.457
2vtqLZACyclin-dependent kinase 22.7.11.220.457
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.457
3oom507Activin receptor type-12.7.11.300.457
3rak03ZCyclin-dependent kinase 22.7.11.220.457
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.457
4bbfO19Tyrosine-protein kinase JAK2/0.457
4bcqTJFCyclin-dependent kinase 22.7.11.220.457
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.457
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.457
4wkqIREEpidermal growth factor receptor2.7.10.10.457
5dt3ATPAurora kinase A2.7.11.10.457
5e92ANPTGF-beta receptor type-22.7.11.300.457
2eb3ANPEpidermal growth factor receptor2.7.10.10.456
2w05FRTCyclin-dependent kinase 22.7.11.220.456
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.456
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.456
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.456
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.456
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.456
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
3gc9B45Mitogen-activated protein kinase 112.7.11.240.455
3ggfGVDSerine/threonine-protein kinase 26/0.455
3iok1P6Tyrosine-protein kinase JAK2/0.455
3u4uLNHCasein kinase II subunit alpha2.7.11.10.455
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.455
5aaaVGHALK tyrosine kinase receptor2.7.10.10.455
2itvANPEpidermal growth factor receptor2.7.10.10.454
2yaaATPDeath-associated protein kinase 2/0.454
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.454
4bchT7ZCyclin-dependent kinase 92.7.11.220.454
4bgg844Activin receptor type-12.7.11.300.454
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.454
4jboWPHAurora kinase A2.7.11.10.454
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.454
1oiyN41Cyclin-dependent kinase 22.7.11.220.453
1vjy460TGF-beta receptor type-12.7.11.300.453
2bujSTUSerine/threonine-protein kinase 16/0.453
2ckeIQUDeath-associated protein kinase 2/0.453
2dwbANPAurora kinase A2.7.11.10.453
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.453
2zjwREFCasein kinase II subunit alpha2.7.11.10.453
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.453
4grb0XGCasein kinase II subunit alpha2.7.11.10.453
4i231C9Epidermal growth factor receptor2.7.10.10.453
4jbpYPHAurora kinase A2.7.11.10.453
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
2vwy7X5Ephrin type-B receptor 42.7.10.10.452
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.452
3at3ATKCasein kinase II subunit alpha2.7.11.10.452
3igoANPCalmodulin-domain protein kinase 1, putative/0.452
3nynSGVG protein-coupled receptor kinase 62.7.11.160.452
3pxkPXKFocal adhesion kinase 12.7.10.20.452
4c57FEFCyclin-G-associated kinase2.7.11.10.452
4f081RSTyrosine-protein kinase JAK2/0.452
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.452
4hge15VTyrosine-protein kinase JAK2/0.452
4ix6ADPUncharacterized protein/0.452
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.451
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.451
2fvdLIACyclin-dependent kinase 22.7.11.220.451
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.451
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.451
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.451
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.451
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.451
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.451
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.451
1cdeGARPhosphoribosylglycinamide formyltransferase/0.450
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1ke6LS2Cyclin-dependent kinase 22.7.11.220.450
1qmzATPCyclin-dependent kinase 22.7.11.220.450
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.450
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.450
2vwz7X6Ephrin type-B receptor 42.7.10.10.450
2y6o1N1Ephrin type-A receptor 42.7.10.10.450
3my5RFZCyclin-dependent kinase 22.7.11.220.450
3w2rW2REpidermal growth factor receptor2.7.10.10.450
4btjADPTau-tubulin kinase 12.7.11.10.450
4dgnLU2Casein kinase II subunit alpha2.7.11.10.450
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.450
4mcb21WtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.450
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.449
1oecAA2Fibroblast growth factor receptor 2/0.449
1wvxBD4Death-associated protein kinase 12.7.11.10.449
2cchATPCyclin-dependent kinase 22.7.11.220.449
2vv9IM9Cyclin-dependent kinase 22.7.11.220.449
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.449
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.449
2zybKSLTyrosine-protein kinase Lck2.7.10.20.449
3c4wATPRhodopsin kinase/0.449
4bcnT9NCyclin-dependent kinase 22.7.11.220.449
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.449
4o0sADNAurora kinase A2.7.11.10.449
4qmpDKISerine/threonine-protein kinase 242.7.11.10.449
1py5PY1TGF-beta receptor type-12.7.11.300.448
2uzbC75Cyclin-dependent kinase 22.7.11.220.448
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.448
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4c02TAKActivin receptor type-12.7.11.300.448
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4id71G0Activated CDC42 kinase 1/0.448
4ii5ADPCyclin-dependent kinase 22.7.11.220.448
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.448
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.447
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.447
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.447
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.447
3bqr4RBDeath-associated protein kinase 3/0.447
4aguD15Cyclin-dependent kinase-like 1/0.447
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.447
4dgo0JWCasein kinase II subunit alpha2.7.11.10.447
4o0wADNAurora kinase A2.7.11.10.447
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4wsqKSAAP2-associated protein kinase 12.7.11.10.447
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.447
1urwI1PCyclin-dependent kinase 22.7.11.220.446
1ykr628Cyclin-dependent kinase 22.7.11.220.446
2c475IDCasein kinase I isoform gamma-2/0.446
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.446
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.446
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.446
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.446
3s4qNK0Mitogen-activated protein kinase 14/0.446
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.446
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.446
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.446
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.446
4jr3KJREpidermal growth factor receptor2.7.10.10.446
4k33ACPFibroblast growth factor receptor 32.7.10.10.446
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
1gih1PUCyclin-dependent kinase 22.7.11.220.445
2f2cAP9Cyclin-dependent kinase 62.7.11.220.445
2izrBRKCasein kinase I isoform gamma-32.7.11.10.445
2izsBRQCasein kinase I isoform gamma-32.7.11.10.445
2py3ACPFibroblast growth factor receptor 2/0.445
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.445
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.445
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.445
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.445
3wmxNADNAD dependent epimerase/dehydratase/0.445
4dymIYZActivin receptor type-12.7.11.300.445
4ewhT77Activated CDC42 kinase 1/0.445
4fv9E71Mitogen-activated protein kinase 12.7.11.240.445
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.445
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.445
4yuqKS1Calmodulin-like domain protein kinase/0.445
1di8DTQCyclin-dependent kinase 22.7.11.220.444
1fvv107Cyclin-dependent kinase 22.7.11.220.444
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.444
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.444
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.444
3vs3VSETyrosine-protein kinase HCK2.7.10.20.444
5cnnANPEpidermal growth factor receptor2.7.10.10.444
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.443
2c6eHPMAurora kinase A2.7.11.10.443
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.443
2q7vFADThioredoxin reductase/0.443
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.443
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.443
3sheI85MAP kinase-activated protein kinase 32.7.11.10.443
4bgh3I6Cyclin-dependent kinase 22.7.11.220.443
4btjATPTau-tubulin kinase 12.7.11.10.443
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.443
4h3qANPMitogen-activated protein kinase 12.7.11.240.443
4ivb1J5Tyrosine-protein kinase JAK1/0.443
4otiMI1Serine/threonine-protein kinase N1/0.443
5aacVGHALK tyrosine kinase receptor2.7.10.10.443
5cvhADPCasein kinase II subunit alpha2.7.11.10.443
5l8lADPAurora kinase A2.7.11.10.443
1bxoPP7Penicillopepsin-13.4.23.200.442
1oitHDTCyclin-dependent kinase 22.7.11.220.442
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3a7hATPSerine/threonine-protein kinase 242.7.11.10.442
3gu7ADPDeath-associated protein kinase 12.7.11.10.442
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.442
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.442
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.442
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.442
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.442
1me7MOAInosine-5'-monophosphate dehydrogenase/0.441
2q9fC3SCholesterol 24-hydroxylase/0.441
2uzdC85Cyclin-dependent kinase 22.7.11.220.441
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3r9hZ67Cyclin-dependent kinase 22.7.11.220.441
3rmf20ZCyclin-dependent kinase 22.7.11.220.441
3s1h56ZCyclin-dependent kinase 22.7.11.220.441
3vs1VSATyrosine-protein kinase HCK2.7.10.20.441
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.441
4f630S7Fibroblast growth factor receptor 1/0.441
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.441
4g1wG1WMitogen-activated protein kinase 82.7.11.240.441
1bwsNDPGDP-L-fucose synthase/0.440
2c4g514Cyclin-dependent kinase 22.7.11.220.440
2j0k4STFocal adhesion kinase 12.7.10.20.440
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.440
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2wihP48Cyclin-dependent kinase 22.7.11.220.440
2wipP49Cyclin-dependent kinase 22.7.11.220.440
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.440
3kf7L9GMitogen-activated protein kinase 14/0.440
3le62BZCyclin-dependent kinase 22.7.11.220.440
3rvg17PTyrosine-protein kinase JAK2/0.440
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.440
4c58824Cyclin-G-associated kinase2.7.11.10.440
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.440
4gu94GUFocal adhesion kinase 12.7.10.20.440
4iva1J5Tyrosine-protein kinase JAK2/0.440
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.440
4nks2M2Fibroblast growth factor receptor 1/0.440
4o701QKBromodomain-containing protein 4/0.440
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
5dt0SKEAurora kinase A2.7.11.10.440