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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3r04UNQSerine/threonine-protein kinase pim-12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3r04UNQSerine/threonine-protein kinase pim-12.7.11.11.000
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.596
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.592
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.591
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.577
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.573
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.564
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.563
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.563
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.559
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.557
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.552
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.551
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.550
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.550
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.549
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.547
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.547
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.545
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.545
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.542
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.542
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.540
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.540
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.534
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.534
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.533
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.532
3umw596Serine/threonine-protein kinase pim-12.7.11.10.532
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.530
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.529
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.528
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.526
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.522
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.522
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.519
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.518
4bgg844Activin receptor type-12.7.11.300.518
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.517
3nga3NGCasein kinase II subunit alpha2.7.11.10.516
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.516
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.514
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.511
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.511
3at4CCKCasein kinase II subunit alpha2.7.11.10.508
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.508
4dgnLU2Casein kinase II subunit alpha2.7.11.10.508
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.504
3mtfA3FActivin receptor type-12.7.11.300.503
3q9xEMOCasein kinase II subunit alpha2.7.11.10.501
2iw84SPCyclin-dependent kinase 22.7.11.220.499
3mdvCL6Cholesterol 24-hydroxylase/0.498
1om1IQACasein kinase II subunit alpha2.7.11.10.497
3r0tFU9Casein kinase II subunit alpha2.7.11.10.495
4grb0XGCasein kinase II subunit alpha2.7.11.10.495
5cu6ATPCasein kinase II subunit alpha2.7.11.10.494
1oiyN41Cyclin-dependent kinase 22.7.11.220.493
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.493
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.493
4ux9ANPMitogen-activated protein kinase 82.7.11.240.493
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.492
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.492
4gmy0X5Tyrosine-protein kinase JAK2/0.492
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.491
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.491
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
1xjdSTUProtein kinase C theta type2.7.11.130.490
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.489
3be9P04Casein kinase II subunit alpha2.7.11.10.489
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.489
2pvnP63Casein kinase II subunit alpha2.7.11.10.488
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.488
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.488
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.487
3pe2E1BCasein kinase II subunit alpha2.7.11.10.487
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.487
4dymIYZActivin receptor type-12.7.11.300.486
1bsvNDPGDP-L-fucose synthase/0.485
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.485
4qmpDKISerine/threonine-protein kinase 242.7.11.10.485
5cvhADPCasein kinase II subunit alpha2.7.11.10.485
1rfvADPPyridoxal kinase2.7.1.350.484
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.484
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.483
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.483
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.483
2wihP48Cyclin-dependent kinase 22.7.11.220.481
3u4uLNHCasein kinase II subunit alpha2.7.11.10.481
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.480
3owj1ELCasein kinase II subunit alpha2.7.11.10.480
1bygSTUTyrosine-protein kinase CSK/0.479
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.479
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.479
3oom507Activin receptor type-12.7.11.300.479
4enhFVXCholesterol 24-hydroxylase/0.479
4g1wG1WMitogen-activated protein kinase 82.7.11.240.479
1jioDEB6-deoxyerythronolide B hydroxylase/0.478
3mb601ICasein kinase II subunit alpha2.7.11.10.478
4c02TAKActivin receptor type-12.7.11.300.478
4jq8KJ8Epidermal growth factor receptor2.7.10.10.478
4tuvCPZCytochrome P450 1191.140.478
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
2h96893Mitogen-activated protein kinase 82.7.11.240.477
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.477
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.477
3vt9YI4Vitamin D3 receptor/0.477
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.477
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.477
3at3ATKCasein kinase II subunit alpha2.7.11.10.476
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.476
3vt8YI3Vitamin D3 receptor/0.476
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.476
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.476
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.476
1vjy460TGF-beta receptor type-12.7.11.300.475
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.475
4qmySTUSerine/threonine-protein kinase 242.7.11.10.475
1m2rMNYCasein kinase II subunit alpha2.7.11.10.474
4dgmAGICasein kinase II subunit alpha2.7.11.10.474
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.474
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.473
2p33J07Mitogen-activated protein kinase 102.7.11.240.473
3gwfFADCyclohexanone monooxygenase/0.473
4bbe3O4Tyrosine-protein kinase JAK2/0.473
4ryvZEAProtein LlR18A/0.473
1fxsNAPGDP-L-fucose synthase/0.472
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.472
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.472
2q9fC3SCholesterol 24-hydroxylase/0.472
2zdu446Mitogen-activated protein kinase 102.7.11.240.472
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.472
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.472
2wotZZGTGF-beta receptor type-12.7.11.300.471
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.471
4c4jX21Dual specificity protein kinase TTK2.7.12.10.471
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.471
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.470
3v3vMYUMitogen-activated protein kinase 82.7.11.240.470
4i22IREEpidermal growth factor receptor2.7.10.10.470
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.470
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.470
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.469
3du8553Glycogen synthase kinase-3 beta2.7.11.260.469
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.469
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.469
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.469
1oi9N20Cyclin-dependent kinase 22.7.11.220.468
2iw94SPCyclin-dependent kinase 22.7.11.220.468
2zdt46CMitogen-activated protein kinase 102.7.11.240.468
3ormAGSSerine/threonine protein kinase/0.468
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.468
4gub0Y4Casein kinase II subunit alpha2.7.11.10.468
4j97ACPFibroblast growth factor receptor 2/0.468
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.468
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.468
5e8xSTUTGF-beta receptor type-12.7.11.300.468
1dawANPCasein kinase II subunit alpha2.7.11.10.467
1lp4ANPCasein kinase II subunit alpha2.7.11.10.467
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.467
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.467
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.467
5e8wSTUTGF-beta receptor type-12.7.11.300.467
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1fmjRTLRetinol dehydratase/0.466
1zys199Serine/threonine-protein kinase Chk12.7.11.10.466
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
3rak03ZCyclin-dependent kinase 22.7.11.220.466
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1k7l544Peroxisome proliferator-activated receptor alpha/0.465
3gxlQIGTGF-beta receptor type-12.7.11.300.465
3zuxTCHTransporter/0.465
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.465
4dgo0JWCasein kinase II subunit alpha2.7.11.10.465
4jqeANPCasein kinase II subunit alpha2.7.11.10.465
4riyADPEpidermal growth factor receptor2.7.10.10.465
4yuqKS1Calmodulin-like domain protein kinase/0.465
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.465
1di8DTQCyclin-dependent kinase 22.7.11.220.464
2qo9ANPEphrin type-A receptor 32.7.10.10.464
2wxvWXVCyclin-dependent kinase 22.7.11.220.464
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.464
1xddAAYIntegrin alpha-L/0.463
2hog710Serine/threonine-protein kinase Chk12.7.11.10.463
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.463
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.463
2nq8ZIDEnoyl-ACP reductase/0.463
3a60STURibosomal protein S6 kinase beta-12.7.11.10.463
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.463
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4ez50RSCyclin-dependent kinase 62.7.11.220.463
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.463
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.463
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
2pvhP19Casein kinase II subunit alpha2.7.11.10.462
2xikJ60Serine/threonine-protein kinase 252.7.11.10.462
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.462
3l8p0CEAngiopoietin-1 receptor2.7.10.10.462
3vt7VDXVitamin D3 receptor/0.462
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4hgt15GCasein kinase I isoform delta2.7.11.10.462
4jr7GNPCasein kinase II subunit alpha2.7.11.10.462
4kbk1QGCasein kinase I isoform delta2.7.11.10.462
2excJNKMitogen-activated protein kinase 102.7.11.240.461
2pvlP55Casein kinase II subunit alpha2.7.11.10.461
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.461
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.461
2zjwREFCasein kinase II subunit alpha2.7.11.10.461
3iw4LW4Protein kinase C alpha type2.7.11.130.461
3oroAGSSerine/threonine protein kinase/0.461
3r71X86Cyclin-dependent kinase 22.7.11.220.461
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4gg70J8Hepatocyte growth factor receptor2.7.10.10.461
4kb81QNCasein kinase I isoform delta2.7.11.10.461
1aq1STUCyclin-dependent kinase 22.7.11.220.460
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.460
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.460
3mdmFJZCholesterol 24-hydroxylase/0.460
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
4e5yNDPGDP-L-fucose synthase1.1.1.2710.460
4e730NRMitogen-activated protein kinase 82.7.11.240.460
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.460
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.460
1pkdUCNCyclin-dependent kinase 22.7.11.220.459
1ywrLI9Mitogen-activated protein kinase 14/0.459
2uxpCLMHTH-type transcriptional regulator TtgR/0.459
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.459
3ral04ZCyclin-dependent kinase 22.7.11.220.459
4c59FEFCyclin-G-associated kinase2.7.11.10.459
4eol1ROCyclin-dependent kinase 22.7.11.220.459
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.459
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
5cvfATPCasein kinase II subunit alpha2.7.11.10.459
1m2pHNACasein kinase II subunit alpha2.7.11.10.458
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.458
1wlvCOAPhenylacetic acid degradation protein PaaI/0.458
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.458
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2q7vFADThioredoxin reductase/0.458
2w05FRTCyclin-dependent kinase 22.7.11.220.458
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.458
3sheI85MAP kinase-activated protein kinase 32.7.11.10.458
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.458
4q73FADBifunctional protein PutA/0.458
4rupH97Vitamin D3 receptor A/0.458
1fvv107Cyclin-dependent kinase 22.7.11.220.457
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.457
1u54ACPActivated CDC42 kinase 1/0.457
2vf0F89Thymidylate synthase/0.457
2xa4AZ5Tyrosine-protein kinase JAK2/0.457
3a4vNADNDP-sugar epimerase/0.457
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.457
3mqe416Prostaglandin G/H synthase 21.14.99.10.457
3pe6ZYHMonoglyceride lipase/0.457
3q9zTXQCasein kinase II subunit alpha2.7.11.10.457
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.457
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.457
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.457
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.457
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
1gij2PUCyclin-dependent kinase 22.7.11.220.456
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.456
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1kkq471Peroxisome proliferator-activated receptor alpha/0.456
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.456
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3gc9B45Mitogen-activated protein kinase 112.7.11.240.456
3oqkS52Renin3.4.23.150.456
3pe13NGCasein kinase II subunit alpha2.7.11.10.456
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
1iyzNDPProbable quinone oxidoreductase/0.455
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.455
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.455
2w17I19Cyclin-dependent kinase 22.7.11.220.455
3ig7EFPCyclin-dependent kinase 22.7.11.220.455
3owk18ECasein kinase II subunit alpha2.7.11.10.455
3qtzX42Cyclin-dependent kinase 22.7.11.220.455
3roy22ZCyclin-dependent kinase 22.7.11.220.455
3ttjJBIMitogen-activated protein kinase 102.7.11.240.455
3vrwYS5Vitamin D3 receptor/0.455
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.455
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.455
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.455
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.455
4lfiGNPCasein kinase II subunit alpha2.7.11.10.455
4wboANWRhodopsin kinase/0.455
5cshATPCasein kinase II subunit alpha2.7.11.10.455
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.454
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.454
2itqITQEpidermal growth factor receptor2.7.10.10.454
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.454
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.454
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3qu0X40Cyclin-dependent kinase 22.7.11.220.454
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.454
4g170VNCasein kinase I isoform gamma-32.7.11.10.454
4hvh19RTyrosine-protein kinase JAK32.7.10.20.454
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.454
4othDRNSerine/threonine-protein kinase N1/0.454
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.454
1j7lADPAminoglycoside 3'-phosphotransferase2.7.1.950.453
2cchATPCyclin-dependent kinase 22.7.11.220.453
2i40BLZCyclin-dependent kinase 22.7.11.220.453
2uxoTACHTH-type transcriptional regulator TtgR/0.453
3nux3NVCyclin-dependent kinase 62.7.11.220.453
3r9dX6BCyclin-dependent kinase 22.7.11.220.453
4anmWULCasein kinase II subunit alpha2.7.11.10.453
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.453
4gk2L66Ephrin type-A receptor 32.7.10.10.453
4hge15VTyrosine-protein kinase JAK2/0.453
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.453
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.453
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.452
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.452
3ddpRC8Cyclin-dependent kinase 22.7.11.220.452
3gobHXXDdmC/0.452
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.452
3r9hZ67Cyclin-dependent kinase 22.7.11.220.452
3u9eCOALmo1369 protein/0.452
3vtdTKDVitamin D3 receptor/0.452
3w5rLOAVitamin D3 receptor/0.452
4fkv61KCyclin-dependent kinase 22.7.11.220.452
4hni16WCasein kinase I isoform epsilon2.7.11.10.452
1ie4T44Transthyretin/0.451
1ouk084Mitogen-activated protein kinase 14/0.451
1u4dDBQActivated CDC42 kinase 1/0.451
1v0oINRCell division control protein 2 homolog2.7.11.220.451
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.451
1zrzBI1Protein kinase C iota type2.7.11.130.451
2bkzSBCCyclin-dependent kinase 22.7.11.220.451
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.451
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.451
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.451
2izrBRKCasein kinase I isoform gamma-32.7.11.10.451
2q61SF1Peroxisome proliferator-activated receptor gamma/0.451
3axwTIDCasein kinase II subunit alpha2.7.11.10.451
3cgfJNFMitogen-activated protein kinase 102.7.11.240.451
3gubGUBDeath-associated protein kinase 12.7.11.10.451
3uli1N3Cyclin-dependent kinase 22.7.11.220.451
3unk0BYCyclin-dependent kinase 22.7.11.220.451
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.451
4bchT7ZCyclin-dependent kinase 92.7.11.220.451
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.451
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.451
4gk3L87Ephrin type-A receptor 32.7.10.10.451
4ix6ADPUncharacterized protein/0.451
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1bwsNDPGDP-L-fucose synthase/0.450
1bxoPP7Penicillopepsin-13.4.23.200.450
1h1s4SPCyclin-dependent kinase 22.7.11.220.450
1k6cMK1Gag-Pol polyprotein3.4.23.160.450
1k6tXN1Gag-Pol polyprotein3.4.23.160.450
1oiuN76Cyclin-dependent kinase 22.7.11.220.450
1rfuADPPyridoxal kinase2.7.1.350.450
2b1pAIZMitogen-activated protein kinase 102.7.11.240.450
2jn3JN3Fatty acid-binding protein, liver/0.450
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.450
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.450
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.450
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.450
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4eiyZMAAdenosine receptor A2a/0.450
4fv7E94Mitogen-activated protein kinase 12.7.11.240.450
4hgs15GCasein kinase I isoform gamma-32.7.11.10.450
4jia1K3Tyrosine-protein kinase JAK2/0.450
4o0wADNAurora kinase A2.7.11.10.450
4wkqIREEpidermal growth factor receptor2.7.10.10.450
1g67TZPThiamine-phosphate synthase/0.449
1ia3TQ5Dihydrofolate reductase1.5.1.30.449
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.449
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.449
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.449
1y0s331Peroxisome proliferator-activated receptor delta/0.449
1zeoC01Peroxisome proliferator-activated receptor gamma/0.449
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.449
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.449
2in6839Wee1-like protein kinase2.7.10.20.449
2vu3LZECyclin-dependent kinase 22.7.11.220.449
3gw9VNILanosterol 14-alpha-demethylase/0.449
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3ortAGSSerine/threonine protein kinase/0.449
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.449
4a99FADTetX family tetracycline inactivation enzyme/0.449
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.449
4c62XWWTyrosine-protein kinase JAK2/0.449
4fkt48KCyclin-dependent kinase 22.7.11.220.449
4fx360KCyclin-dependent kinase 22.7.11.220.449
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4qa0SHHHistone deacetylase 83.5.1.980.449
4u7wNDPMxaA/0.449
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.449
1g6cTZPThiamine-phosphate synthase/0.448
1ke6LS2Cyclin-dependent kinase 22.7.11.220.448
1pmn984Mitogen-activated protein kinase 102.7.11.240.448
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.448
2ckeIQUDeath-associated protein kinase 2/0.448
2oiqSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
3c3xNAPEugenol synthase 11.1.1.3180.448
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
3gu83GUDeath-associated protein kinase 12.7.11.10.448
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
3oev3OEProteasome subunit beta type-53.4.25.10.448
3oev3OEProteasome subunit beta type-63.4.25.10.448
4a862ANMajor pollen allergen Bet v 1-A/0.448
4b99R4LMitogen-activated protein kinase 72.7.11.240.448
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
4hnf16WCasein kinase I isoform delta2.7.11.10.448
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.448
4ocvANPAminoglycoside phosphotransferase/0.448
4rrxLURProstaglandin G/H synthase 21.14.99.10.448
1dhiMTXDihydrofolate reductase1.5.1.30.447
1m2qMNXCasein kinase II subunit alpha2.7.11.10.447
2henADPEphrin type-B receptor 22.7.10.10.447
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.447
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.447
2vwx7X4Ephrin type-B receptor 42.7.10.10.447
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.447
3a4pDFQHepatocyte growth factor receptor2.7.10.10.447
3abaFLICytochrome P450/0.447
3eljGS7Mitogen-activated protein kinase 82.7.11.240.447
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3hx4ANPCalmodulin-domain protein kinase 1/0.447
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.447
3rmf20ZCyclin-dependent kinase 22.7.11.220.447
3ttiKBIMitogen-activated protein kinase 102.7.11.240.447
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.447
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.447
4fkw62KCyclin-dependent kinase 22.7.11.220.447
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.447
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.447
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.447
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1eh4IC1Casein kinase I homolog 12.7.11.10.446
1jmhUMPThymidylate synthase/0.446
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.446
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.446
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.446
2wpa889Cyclin-dependent kinase 22.7.11.220.446
3ibqATPPyridoxal kinase/0.446
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3nwq2NCGag-Pol polyprotein3.4.23.160.446
3p3zP3ZPutative cytochrome P450/0.446
3p84FMNPentaerythritol tetranitrate reductase/0.446
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.446
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.446
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.446
4eok4SPCyclin-dependent kinase 22.7.11.220.446
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.446
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.446
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.446
4nc3ERM5-hydroxytryptamine receptor 2B/0.446
4o701QKBromodomain-containing protein 4/0.446
4uymVOR14-alpha sterol demethylase Cyp51B/0.446
4xgxADPFAD:protein FMN transferase/0.446
1fmlRTLRetinol dehydratase/0.445
1jpaANPEphrin type-B receptor 22.7.10.10.445
1v0pPVBCell division control protein 2 homolog2.7.11.220.445
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2b52D42Cyclin-dependent kinase 22.7.11.220.445
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.445
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.445
2j0j4STFocal adhesion kinase 12.7.10.20.445
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.445
2xnbY8LCyclin-dependent kinase 22.7.11.220.445
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.445
3nbwTR4Ketohexokinase/0.445
3u8w09JMitogen-activated protein kinase 14/0.445
3vvpBNUUncharacterized protein/0.445
3zewSTUEphrin type-B receptor 42.7.10.10.445
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4bcoT6QCyclin-dependent kinase 22.7.11.220.445
4erwSTUCyclin-dependent kinase 22.7.11.220.445
4fob0USALK tyrosine kinase receptor2.7.10.10.445
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1f4gTP4Thymidylate synthase/0.444
1nytNAPShikimate dehydrogenase (NADP(+))/0.444
1ppm0P1Penicillopepsin-13.4.23.200.444
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.444
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1tduCB3Thymidylate synthase/0.444
1x8lOXRRetinol dehydratase/0.444
1xl2189Gag-Pol polyprotein3.4.23.160.444
2c6tDT5Cyclin-dependent kinase 22.7.11.220.444
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.444
2vwz7X6Ephrin type-B receptor 42.7.10.10.444
3hazFADBifunctional protein PutA/0.444
3p7nFMNLight-activated DNA-binding protein EL222/0.444
3qzhX69Cyclin-dependent kinase 22.7.11.220.444
3s1h56ZCyclin-dependent kinase 22.7.11.220.444
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.444
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.444
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4c57FEFCyclin-G-associated kinase2.7.11.10.444
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.444
4iteTEYVitamin D3 receptor/0.444
4nxvGDPMitochondrial dynamics protein MID51/0.444
4q71FADBifunctional protein PutA/0.444
4qmzB49Serine/threonine-protein kinase 242.7.11.10.444
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.444
5av2KMPDeath-associated protein kinase 12.7.11.10.444
1gih1PUCyclin-dependent kinase 22.7.11.220.443
1jipKTN6-deoxyerythronolide B hydroxylase/0.443
1q4t4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.443
1vyw292Cyclin-dependent kinase 22.7.11.220.443
2dr3ADPUPF0273 protein PH0284/0.443
2izsBRQCasein kinase I isoform gamma-32.7.11.10.443
2j0k4STFocal adhesion kinase 12.7.10.20.443
2q5g1FAPeroxisome proliferator-activated receptor delta/0.443
2uzlC94Cyclin-dependent kinase 22.7.11.220.443
3a1nNADNDP-sugar epimerase/0.443
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3bqr4RBDeath-associated protein kinase 3/0.443
3mtlFEFCyclin-dependent kinase 162.7.11.220.443
3oriAGSSerine/threonine protein kinase/0.443
3owl19ECasein kinase II subunit alpha2.7.11.10.443
3rni21ZCyclin-dependent kinase 22.7.11.220.443
3slkNDPPolyketide synthase extender module 2/0.443
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.443
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fgg0U5Dihydrofolate reductase1.5.1.30.443
4gu94GUFocal adhesion kinase 12.7.10.20.443
4ix5ANPUncharacterized protein/0.443
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.443
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.443
1cjkFOKAdenylate cyclase type 2/0.442
1cjkFOKAdenylate cyclase type 5/0.442
1cqp803Integrin alpha-L/0.442
1e7qNAPGDP-L-fucose synthase/0.442
1ke7LS3Cyclin-dependent kinase 22.7.11.220.442
1vruAAPGag-Pol polyprotein2.7.7.490.442
2dvlFADAcyl-CoA dehydrogenase/0.442
2i5bADPPyridoxine kinase/0.442
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.442
2itnANPEpidermal growth factor receptor2.7.10.10.442
2w06FRVCyclin-dependent kinase 22.7.11.220.442
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.442
2wecPP5Penicillopepsin-13.4.23.200.442
2zbaZBATrichothecene 3-O-acetyltransferase/0.442
3r354CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.442
3sdkP3NProteasome subunit beta type-53.4.25.10.442
3sdkP3NProteasome subunit beta type-63.4.25.10.442
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.442
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.442
4e4m0NHTyrosine-protein kinase JAK2/0.442
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.442
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.442
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.442
5dr6SKEAurora kinase A2.7.11.10.442
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
1l2jETCEstrogen receptor beta/0.441
1phgMYTCamphor 5-monooxygenase1.14.15.10.441
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.441
1qxlFR8Adenosine deaminase3.5.4.40.441
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.441
2eufLQQCyclin-dependent kinase 62.7.11.220.441
2hw2RFPRifampin ADP-ribosyl transferase/0.441
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.441
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.441
2vx07X7Ephrin type-B receptor 42.7.10.10.441
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.441
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.441
3dd125DGlycogen phosphorylase, liver form2.4.1.10.441
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.441
3p99LNPLanosterol 14-alpha-demethylase/0.441
3qqkX02Cyclin-dependent kinase 22.7.11.220.441
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.441
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.441
4hvg19QTyrosine-protein kinase JAK32.7.10.20.441
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.441
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
4ly91YYGlucokinase regulatory protein/0.441
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.441
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1h1r6CPCyclin-dependent kinase 22.7.11.220.440
1m13HYFNuclear receptor subfamily 1 group I member 2/0.440
1m17AQ4Epidermal growth factor receptor2.7.10.10.440
1oguST8Cyclin-dependent kinase 22.7.11.220.440
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.440
2c27ACOMycothiol acetyltransferase2.3.1.1890.440
2chlDKICasein kinase I isoform gamma-32.7.11.10.440
2dwbANPAurora kinase A2.7.11.10.440
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.440
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2igoFADPyranose 2-oxidase/0.440
2jedLG8Protein kinase C theta type2.7.11.130.440
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.440
3bhtMFRCyclin-dependent kinase 22.7.11.220.440
3eek53SUncharacterized protein/0.440
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.440
3mvl38PMitogen-activated protein kinase 14/0.440
3pxyJWSCyclin-dependent kinase 22.7.11.220.440
3rpv26ZCyclin-dependent kinase 22.7.11.220.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4bcmT7ZCyclin-dependent kinase 22.7.11.220.440
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.440
5c41ACPRibokinase/0.440
5k2cZMAAdenosine receptor A2a/0.440