sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qto | 10P | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3qto | 10P | Prothrombin | 3.4.21.5 | 1.000 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.870 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.806 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.800 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.773 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.772 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.764 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.759 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.748 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.737 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.735 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.719 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.718 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.701 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.696 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.691 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.686 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.683 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.681 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.680 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.673 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.670 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.670 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.666 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.666 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.661 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.658 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.658 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.657 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.657 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.655 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.654 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.654 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.653 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.648 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.639 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.638 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.632 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.625 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.624 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.624 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.622 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.618 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.615 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.614 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.613 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.612 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.611 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.607 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.606 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.605 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.603 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.601 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.600 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.599 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.598 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.597 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.593 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.593 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.590 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.590 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.590 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.589 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.589 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.589 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.589 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.588 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.587 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.585 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.582 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.581 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.581 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.577 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.576 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.574 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.573 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.573 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.572 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.572 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.572 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.571 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.570 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.570 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.565 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.562 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.561 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.561 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.559 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.559 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.553 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.550 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.548 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.548 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.546 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.546 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.545 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.539 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.538 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.534 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.529 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.528 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.525 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.521 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.513 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.507 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.504 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.501 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.498 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.496 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.491 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.490 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.490 | |
| 3f68 | 91U | Prothrombin | 3.4.21.5 | 0.485 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.485 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.484 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.482 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.481 | |
| 1uvs | I11 | Prothrombin | 3.4.21.5 | 0.479 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.479 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.478 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.478 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.475 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.474 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.474 | |
| 1c1w | BAH | Prothrombin | 3.4.21.5 | 0.473 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.473 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.473 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.473 | |
| 1fml | RTL | Retinol dehydratase | / | 0.472 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.472 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.470 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.470 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.469 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.469 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.468 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.468 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.468 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.468 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.468 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.467 | |
| 3eks | CY9 | Actin-5C | / | 0.467 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.467 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.466 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.466 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.466 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.465 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.465 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.464 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.464 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.464 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.463 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.463 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.462 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.462 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.461 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.461 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.461 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.461 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.460 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.460 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.460 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.460 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.460 | |
| 4frj | DWB | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.459 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.459 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.459 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.459 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.459 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.459 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.458 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.458 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.458 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.458 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.457 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.457 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.457 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.457 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.457 | |
| 2nr4 | FMN | Conserved protein | / | 0.456 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.456 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.456 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.456 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.455 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.455 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.455 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.454 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.454 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.454 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.454 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.453 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.453 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.453 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.453 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.452 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.452 | |
| 3qvi | K95 | HAP protein | / | 0.452 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.452 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.452 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.451 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.451 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.451 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.451 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.451 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.450 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.450 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.449 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.449 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.449 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.449 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.449 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.449 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.449 | |
| 3eku | CY9 | Actin-5C | / | 0.449 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.449 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.449 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.449 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.448 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 1r2j | FAD | FkbI | / | 0.448 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.448 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.448 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.448 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.448 | |
| 3uce | NDP | Dehydrogenase | / | 0.448 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.448 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.448 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 1hzj | UD1 | UDP-glucose 4-epimerase | / | 0.447 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.447 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.447 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.447 | |
| 2owk | SAH | Diphthine synthase | / | 0.447 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.447 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.447 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.447 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 1ppj | ANY | Cytochrome b | / | 0.446 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.446 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.446 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.446 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.446 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4m55 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.446 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.446 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.446 | |
| 5cyo | GDP | Septin-9 | / | 0.446 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.445 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.445 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.445 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.445 | |
| 3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.445 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.444 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.444 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.444 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.444 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.443 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.443 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vnn | CM7 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.443 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4die | C5P | Cytidylate kinase | / | 0.443 | |
| 4ema | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.443 | |
| 4jxr | ACO | Acetyltransferase | / | 0.443 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.442 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2x96 | RX3 | Angiotensin-converting enzyme | 3.4.15.1 | 0.442 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.442 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.442 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.442 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.442 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.442 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.442 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.441 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.441 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.441 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.441 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.441 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.441 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.441 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4l5a | TBN | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.440 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.440 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.440 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.440 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.440 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.440 | |
| 3iaa | TYD | CalG2 | / | 0.440 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.440 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.440 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3r96 | ACO | MccE protein | / | 0.440 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 4h57 | 0PJ | Thermolysin | 3.4.24.27 | 0.440 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.440 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.440 |