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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3fln3FNMitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3fln3FNMitogen-activated protein kinase 14/1.000
3fklFKLMitogen-activated protein kinase 14/0.745
3flzFLZMitogen-activated protein kinase 14/0.724
3flyFLYMitogen-activated protein kinase 14/0.693
3fmkFMKMitogen-activated protein kinase 14/0.683
3flwFLWMitogen-activated protein kinase 14/0.681
3fmh533Mitogen-activated protein kinase 14/0.668
3nww3NWMitogen-activated protein kinase 14/0.652
3fi4FI4Mitogen-activated protein kinase 14/0.650
3fskRO6Mitogen-activated protein kinase 14/0.647
3hl7I47Mitogen-activated protein kinase 14/0.621
2balPQAMitogen-activated protein kinase 14/0.619
4aa4QC0Mitogen-activated protein kinase 14/0.613
4lopSB4Mitogen-activated protein kinase 14/0.609
3hvcGG5Mitogen-activated protein kinase 14/0.606
3iphG11Mitogen-activated protein kinase 14/0.604
4aacAAVMitogen-activated protein kinase 14/0.603
3dt1P40Mitogen-activated protein kinase 14/0.600
3mpt1GKMitogen-activated protein kinase 14/0.599
4aa5NQBMitogen-activated protein kinase 14/0.593
3uyt0CKCasein kinase I isoform delta2.7.11.10.579
4looSB4Mitogen-activated protein kinase 14/0.579
3ocgOCGMitogen-activated protein kinase 14/0.567
4loqSB4Mitogen-activated protein kinase 14/0.566
2rg6287Mitogen-activated protein kinase 14/0.563
2rg5279Mitogen-activated protein kinase 14/0.562
3fmn530Mitogen-activated protein kinase 14/0.562
4kiq1RAMitogen-activated protein kinase 14/0.561
1ywrLI9Mitogen-activated protein kinase 14/0.555
1ouk084Mitogen-activated protein kinase 14/0.552
4kip1R9Mitogen-activated protein kinase 14/0.552
2qd9LGFMitogen-activated protein kinase 14/0.551
2ghlLIBMitogen-activated protein kinase 14/0.548
3mvm39PMitogen-activated protein kinase 14/0.545
4kin1M8Mitogen-activated protein kinase 14/0.545
3s4qNK0Mitogen-activated protein kinase 14/0.544
1zz2B11Mitogen-activated protein kinase 14/0.543
3hllI45Mitogen-activated protein kinase 14/0.542
3mvl38PMitogen-activated protein kinase 14/0.541
3flsFLSMitogen-activated protein kinase 14/0.540
4hnf16WCasein kinase I isoform delta2.7.11.10.534
4kbk1QGCasein kinase I isoform delta2.7.11.10.530
4ewqMWLMitogen-activated protein kinase 14/0.529
3u8w09JMitogen-activated protein kinase 14/0.527
4ic7ANPMitogen-activated protein kinase 72.7.11.240.525
1zyjBI5Mitogen-activated protein kinase 14/0.523
3roc29AMitogen-activated protein kinase 14/0.520
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.520
4eh60ONMitogen-activated protein kinase 14/0.518
3uzp0CKCasein kinase I isoform delta2.7.11.10.513
4eh70OOMitogen-activated protein kinase 14/0.511
3hx4ANPCalmodulin-domain protein kinase 1/0.507
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.505
3uibSB2Putative mitogen-activated protein kinase/0.504
3gw9VNILanosterol 14-alpha-demethylase/0.503
3l8xN4DMitogen-activated protein kinase 14/0.502
2xa4AZ5Tyrosine-protein kinase JAK2/0.501
4kbc1QJCasein kinase I isoform delta2.7.11.10.500
3kf7L9GMitogen-activated protein kinase 14/0.499
3mpaSB2Mitogen-activated protein kinase 14/0.499
3uvqFS8Mitogen-activated protein kinase 14/0.497
3w33W19Epidermal growth factor receptor2.7.10.10.497
4kb81QNCasein kinase I isoform delta2.7.11.10.496
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.496
3uvp048Mitogen-activated protein kinase 14/0.495
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
3gc9B45Mitogen-activated protein kinase 112.7.11.240.493
3gfeP37Mitogen-activated protein kinase 14/0.493
3gu83GUDeath-associated protein kinase 12.7.11.10.492
2xikJ60Serine/threonine-protein kinase 252.7.11.10.491
2vd5BI8Myotonin-protein kinase2.7.11.10.490
3w32W32Epidermal growth factor receptor2.7.10.10.490
4nk92K5Fibroblast growth factor receptor 1/0.490
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.490
1xjdSTUProtein kinase C theta type2.7.11.130.488
1bl6SB6Mitogen-activated protein kinase 14/0.487
1yw2PGJMitogen-activated protein kinase 14/0.486
4b99R4LMitogen-activated protein kinase 72.7.11.240.486
1ywnLIFVascular endothelial growth factor receptor 22.7.10.10.485
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.485
2itpAEEEpidermal growth factor receptor2.7.10.10.484
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.484
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.484
2wouZZFTGF-beta receptor type-12.7.11.300.483
4f650S9Fibroblast growth factor receptor 1/0.483
3bv3P39Mitogen-activated protein kinase 14/0.482
4i22IREEpidermal growth factor receptor2.7.10.10.481
4yuqKS1Calmodulin-like domain protein kinase/0.481
3gc7B45Mitogen-activated protein kinase 14/0.480
3hp552PMitogen-activated protein kinase 14/0.480
1bygSTUTyrosine-protein kinase CSK/0.479
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.479
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.478
2of4979Tyrosine-protein kinase Lck2.7.10.20.478
3gubGUBDeath-associated protein kinase 12.7.11.10.478
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.478
4kba1QMCasein kinase I isoform delta2.7.11.10.478
1m17AQ4Epidermal growth factor receptor2.7.10.10.477
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.477
2of2547Tyrosine-protein kinase Lck2.7.10.20.477
2y6o1N1Ephrin type-A receptor 42.7.10.10.477
1m7qDQOMitogen-activated protein kinase 14/0.476
1nzdUPGDNA beta-glucosyltransferase/0.476
1u4dDBQActivated CDC42 kinase 1/0.476
3qaiXNNKetohexokinase/0.476
3zh8C58Protein kinase C iota type2.7.11.130.476
1jpaANPEphrin type-B receptor 22.7.10.10.475
2izrBRKCasein kinase I isoform gamma-32.7.11.10.475
3atzFMNProstaglandin F2a synthase/0.475
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.475
4fod0UVALK tyrosine kinase receptor2.7.10.10.475
5e8wSTUTGF-beta receptor type-12.7.11.300.475
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.474
2gtmLIDMitogen-activated protein kinase 14/0.474
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.474
4g3jVNTLanosterol 14-alpha-demethylase/0.474
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.474
1k6cMK1Gag-Pol polyprotein3.4.23.160.473
1vjy460TGF-beta receptor type-12.7.11.300.473
2izsBRQCasein kinase I isoform gamma-32.7.11.10.473
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.473
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.473
1zrzBI1Protein kinase C iota type2.7.11.130.472
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.472
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.472
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.472
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.472
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.472
4hjoAQ4Epidermal growth factor receptor2.7.10.10.472
1di8DTQCyclin-dependent kinase 22.7.11.220.471
1ouy094Mitogen-activated protein kinase 14/0.471
1py5PY1TGF-beta receptor type-12.7.11.300.471
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.471
2q7vFADThioredoxin reductase/0.471
2zb0GK3Mitogen-activated protein kinase 14/0.471
4dymIYZActivin receptor type-12.7.11.300.471
4hni16WCasein kinase I isoform epsilon2.7.11.10.471
4i231C9Epidermal growth factor receptor2.7.10.10.471
4jrvKJVEpidermal growth factor receptor2.7.10.10.471
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.471
4qmzB49Serine/threonine-protein kinase 242.7.11.10.471
1gih1PUCyclin-dependent kinase 22.7.11.220.470
2qboCAMCamphor 5-monooxygenase1.14.15.10.470
2vynNADGlyceraldehyde-3-phosphate dehydrogenase A/0.470
3lqfNADGalactitol dehydrogenase/0.470
3tucFPWTyrosine-protein kinase SYK2.7.10.20.470
4gk3L87Ephrin type-A receptor 32.7.10.10.470
1v9aSAHUncharacterized protein/0.469
2ittAEEEpidermal growth factor receptor2.7.10.10.469
2itzIREEpidermal growth factor receptor2.7.10.10.469
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.469
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.469
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.469
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.469
4tuvCPZCytochrome P450 1191.140.469
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.468
3fl4FL4Mitogen-activated protein kinase 14/0.468
3fmjFMJMitogen-activated protein kinase 14/0.468
3zewSTUEphrin type-B receptor 42.7.10.10.468
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.468
4jr3KJREpidermal growth factor receptor2.7.10.10.468
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.467
2cig1DGDihydrofolate reductase1.5.1.30.467
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.467
3hmm855TGF-beta receptor type-12.7.11.300.467
3zmmF9JTyrosine-protein kinase JAK2/0.467
4bgg844Activin receptor type-12.7.11.300.467
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.467
1k6tXN1Gag-Pol polyprotein3.4.23.160.466
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.466
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.466
3a3gDLZLumazine protein/0.466
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.466
3fkoFKOMitogen-activated protein kinase 14/0.466
4g2fC07Ephrin type-A receptor 32.7.10.10.466
4gk2L66Ephrin type-A receptor 32.7.10.10.466
1eh4IC1Casein kinase I homolog 12.7.11.10.465
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.465
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.465
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.465
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.465
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.465
3il1B5DGlutamate receptor 2/0.465
4kb81QOCasein kinase I isoform delta2.7.11.10.465
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
2wotZZGTGF-beta receptor type-12.7.11.300.464
3ac1KZITyrosine-protein kinase Lck2.7.10.20.464
4fuxE75Mitogen-activated protein kinase 12.7.11.240.464
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.463
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.463
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.463
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.463
3oom507Activin receptor type-12.7.11.300.463
3w2rW2REpidermal growth factor receptor2.7.10.10.463
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.463
4nka2K7Fibroblast growth factor receptor 1/0.463
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.462
3c50ADPRhodopsin kinase/0.462
3iok1P6Tyrosine-protein kinase JAK2/0.462
3vjoANPEpidermal growth factor receptor2.7.10.10.462
4c02TAKActivin receptor type-12.7.11.300.462
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.462
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.461
2b7aIZATyrosine-protein kinase JAK2/0.461
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.461
3fc152PMitogen-activated protein kinase 14/0.461
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.461
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.461
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.460
2ghmLICMitogen-activated protein kinase 14/0.460
2hk51BMTyrosine-protein kinase HCK2.7.10.20.460
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.460
3ac2KSETyrosine-protein kinase Lck2.7.10.20.460
3d7zGK5Mitogen-activated protein kinase 14/0.460
4erkOLOMitogen-activated protein kinase 12.7.11.240.460
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.460
4jq8KJ8Epidermal growth factor receptor2.7.10.10.460
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.460
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
1aq1STUCyclin-dependent kinase 22.7.11.220.459
1hncGDNGlutathione S-transferase Mu 22.5.1.180.459
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.459
2jedLG8Protein kinase C theta type2.7.11.130.459
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.459
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.459
4ki8ADP60 kDa chaperonin/0.459
1bxoPP7Penicillopepsin-13.4.23.200.458
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.458
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.458
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.458
4f640S8Fibroblast growth factor receptor 1/0.458
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.458
4hgs15GCasein kinase I isoform gamma-32.7.11.10.458
4hvi19STyrosine-protein kinase JAK32.7.10.20.458
4nfn2KCTau-tubulin kinase 12.7.11.10.458
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.458
5dp2NAPCurF/0.458
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.457
1vikBAYGag-Pol polyprotein/0.457
2xyuQ9GEphrin type-A receptor 42.7.10.10.457
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.457
3hwrNDP2-dehydropantoate 2-reductase/0.457
3mtfA3FActivin receptor type-12.7.11.300.457
3t3c017Gag-Pol polyprotein3.4.23.160.457
3ttiKBIMitogen-activated protein kinase 102.7.11.240.457
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.457
4nks2M2Fibroblast growth factor receptor 1/0.457
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.457
4riyADPEpidermal growth factor receptor2.7.10.10.457
1nzfUPGDNA beta-glucosyltransferase/0.456
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.456
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.456
2fznFADBifunctional protein PutA1.5.5.20.456
2igoFADPyranose 2-oxidase/0.456
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.456
2j0m4STFocal adhesion kinase 12.7.10.20.456
2uzlC94Cyclin-dependent kinase 22.7.11.220.456
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.456
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.456
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.456
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.456
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.456
4aqc88ATyrosine-protein kinase JAK2/0.456
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.456
4jx1CAHCamphor 5-monooxygenase1.14.15.10.456
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.456
1c6yMK1Protease/0.455
1cf3FADGlucose oxidase1.1.3.40.455
1rw8580TGF-beta receptor type-12.7.11.300.455
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2qblCAMCamphor 5-monooxygenase1.14.15.10.455
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.455
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.455
2xvdAS6Ephrin type-B receptor 42.7.10.10.455
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.455
3lu8IQXSerum albumin/0.455
3poz03PEpidermal growth factor receptor2.7.10.10.455
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.455
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
4g7gVFVLanosterol 14-alpha-demethylase/0.455
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.455
1iwiCAMCamphor 5-monooxygenase1.14.15.10.454
1u54ACPActivated CDC42 kinase 1/0.454
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.454
2qo9ANPEphrin type-A receptor 32.7.10.10.454
3ezvEZVCyclin-dependent kinase 22.7.11.220.454
3itzP66Mitogen-activated protein kinase 14/0.454
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.454
3ttjJBIMitogen-activated protein kinase 102.7.11.240.454
4f630S7Fibroblast growth factor receptor 1/0.454
4hvh19RTyrosine-protein kinase JAK32.7.10.20.454
4ih8B43Calmodulin-domain protein kinase 1/0.454
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.453
1rfvADPPyridoxal kinase2.7.1.350.453
1uyePU9Heat shock protein HSP 90-alpha/0.453
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.453
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.453
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.453
2i40BLZCyclin-dependent kinase 22.7.11.220.453
2po7CHDFerrochelatase, mitochondrial4.99.1.10.453
2x1nX1NCyclin-dependent kinase 22.7.11.220.453
3dj4UD1Bifunctional protein GlmU/0.453
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.453
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.453
4a84DXCMajor pollen allergen Bet v 1-A/0.453
4enhFVXCholesterol 24-hydroxylase/0.453
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.453
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.453
4jx1CAMCamphor 5-monooxygenase1.14.15.10.453
1agwSU2Fibroblast growth factor receptor 1/0.452
1y0s331Peroxisome proliferator-activated receptor delta/0.452
2bfyH1NAurora kinase B-A2.7.11.10.452
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.452
2o0uC0MMitogen-activated protein kinase 102.7.11.240.452
2qbmCAMCamphor 5-monooxygenase1.14.15.10.452
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3iw4LW4Protein kinase C alpha type2.7.11.130.452
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.452
4gg70J8Hepatocyte growth factor receptor2.7.10.10.452
4ia3BIVVitamin D3 receptor A/0.452
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.452
1k6pXN3Gag-Pol polyprotein3.4.23.160.451
1ke6LS2Cyclin-dependent kinase 22.7.11.220.451
1qvnFRIInterleukin-2/0.451
1xkkFMMEpidermal growth factor receptor2.7.10.10.451
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2excJNKMitogen-activated protein kinase 102.7.11.240.451
2i0ePDSProtein kinase C beta type2.7.11.130.451
2npaMMBPeroxisome proliferator-activated receptor alpha/0.451
2py3ACPFibroblast growth factor receptor 2/0.451
2q631UNGag-Pol polyprotein3.4.23.160.451
2yaaATPDeath-associated protein kinase 2/0.451
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.451
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.451
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.451
3q92XNBKetohexokinase/0.451
3vryB43Tyrosine-protein kinase HCK2.7.10.20.451
3vs3VSETyrosine-protein kinase HCK2.7.10.20.451
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.451
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.451
4l4bCAMCamphor 5-monooxygenase1.14.15.10.451
4q71FADBifunctional protein PutA/0.451
5aabVGHALK tyrosine kinase receptor2.7.10.10.451
5e8xSTUTGF-beta receptor type-12.7.11.300.451
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1bsvNDPGDP-L-fucose synthase/0.450
1c1dNAIPhenylalanine dehydrogenase/0.450
1phgMYTCamphor 5-monooxygenase1.14.15.10.450
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.450
1u3dFADCryptochrome-1/0.450
1xe55FEPlasmepsin-23.4.23.390.450
1xl5190Gag-Pol polyprotein3.4.23.160.450
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.450
2fgiPD1Fibroblast growth factor receptor 1/0.450
2ftoCB3Thymidylate synthase/0.450
2itnANPEpidermal growth factor receptor2.7.10.10.450
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.450
2vwz7X6Ephrin type-B receptor 42.7.10.10.450
2zybKSLTyrosine-protein kinase Lck2.7.10.20.450
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3hz5Z64Heat shock protein HSP 90-alpha/0.450
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.450
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.450
3zdu38RCyclin-dependent kinase-like 32.7.11.220.450
3zuyTCHTransporter/0.450
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4btkDTQTau-tubulin kinase 12.7.11.10.450
4g160VMCasein kinase I isoform gamma-32.7.11.10.450
4jq7KJQEpidermal growth factor receptor2.7.10.10.450
4nmbFADBifunctional protein PutA/0.450
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.450
1cx4CMPcAMP-dependent protein kinase type II-beta regulatory subunit/0.449
1xddAAYIntegrin alpha-L/0.449
1yvj4STTyrosine-protein kinase JAK32.7.10.20.449
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.449
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.449
3fwfCAMCamphor 5-monooxygenase1.14.15.10.449
3gxlQIGTGF-beta receptor type-12.7.11.300.449
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.449
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.449
3mdmFJZCholesterol 24-hydroxylase/0.449
3vquO22Dual specificity protein kinase TTK2.7.12.10.449
3zsi52PMitogen-activated protein kinase 14/0.449
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.449
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.449
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.449
4iva1J5Tyrosine-protein kinase JAK2/0.449
4nxuADPMitochondrial dynamics protein MID51/0.449
1nooCAHCamphor 5-monooxygenase1.14.15.10.448
2c5nCK8Cyclin-dependent kinase 22.7.11.220.448
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.448
2vww7X2Ephrin type-B receptor 42.7.10.10.448
2wecPP5Penicillopepsin-13.4.23.200.448
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.448
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.448
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.448
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
3ucb017Gag-Pol polyprotein/0.448
3w2sW2REpidermal growth factor receptor2.7.10.10.448
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.448
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.448
4c61LMMTyrosine-protein kinase JAK2/0.448
4cqlNADEstradiol 17-beta-dehydrogenase 81.1.1.620.448
4e4m0NHTyrosine-protein kinase JAK2/0.448
4ejmNAPPutative zinc-binding dehydrogenase/0.448
4f9wLM4Mitogen-activated protein kinase 14/0.448
4gmy0X5Tyrosine-protein kinase JAK2/0.448
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
4qms1N1Serine/threonine-protein kinase 242.7.11.10.448
5aaaVGHALK tyrosine kinase receptor2.7.10.10.448
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.447
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.447
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.447
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.447
2d8aNADL-threonine 3-dehydrogenase/0.447
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.447
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3c4wATPRhodopsin kinase/0.447
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.447
3d1xROCGag-Pol polyprotein3.4.23.160.447
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
3i6oGR6Gag-Pol polyprotein3.4.23.160.447
3iaeD7KBenzaldehyde lyase/0.447
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.447
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.447
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.447
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.447
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.447
4uymVOR14-alpha sterol demethylase Cyp51B/0.447
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.447
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.446
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
2ca0PXICytochrome P450 monooxygenase PikC/0.446
2idw017Protease/0.446
2xb7GUIALK tyrosine kinase receptor2.7.10.10.446
3at3ATKCasein kinase II subunit alpha2.7.11.10.446
3l63CAMCamphor 5-monooxygenase1.14.15.10.446
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.446
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.446
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.446
4l4fCAMCamphor 5-monooxygenase1.14.15.10.446
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.446
6cp4CAMCamphor 5-monooxygenase1.14.15.10.446
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1ppm0P1Penicillopepsin-13.4.23.200.445
1t7i017Gag-Pol polyprotein3.4.23.160.445
1tehNADAlcohol dehydrogenase class-31.1.1.10.445
2bpw1INGag-Pol polyprotein3.4.23.160.445
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.445
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.445
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.445
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.445
2i0aMUIProtease/0.445
2itwITQEpidermal growth factor receptor2.7.10.10.445
2j5xGSPADP-ribosylation factor 6/0.445
2yn8STUEphrin type-B receptor 42.7.10.10.445
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.445
3d7tSTUTyrosine-protein kinase CSK/0.445
3lfnA27Cyclin-dependent kinase 22.7.11.220.445
3tk3CPZCytochrome P450 2B41.14.14.10.445
3uleC69Actin-related protein 3/0.445
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.445
3wrlCAMCamphor 5-monooxygenase1.14.15.10.445
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.445
4c62XWWTyrosine-protein kinase JAK2/0.445
4cfnJYMCyclin-dependent kinase 22.7.11.220.445
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4g170VNCasein kinase I isoform gamma-32.7.11.10.445
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.445
4jqeANPCasein kinase II subunit alpha2.7.11.10.445
4l4dCAMCamphor 5-monooxygenase1.14.15.10.445
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
4uyf73BBromodomain-containing protein 2/0.445
4xguADPPutative pachytene checkpoint protein 2/0.445
4y9qC2EUncharacterized protein/0.445
1k6vXN2Gag-Pol polyprotein3.4.23.160.444
1phhFADp-hydroxybenzoate hydroxylase/0.444
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.444
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.444
2uxuNARHTH-type transcriptional regulator TtgR/0.444
2vgoAD5Aurora kinase B-A2.7.11.10.444
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.444
3a60STURibosomal protein S6 kinase beta-12.7.11.10.444
3b20NADGlyceraldehyde-3-phosphate dehydrogenase/0.444
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.444
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
3v3vMYUMitogen-activated protein kinase 82.7.11.240.444
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.444
4c57FEFCyclin-G-associated kinase2.7.11.10.444
4ez50RSCyclin-dependent kinase 62.7.11.220.444
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.444
4gu94GUFocal adhesion kinase 12.7.10.20.444
4l4cCAMCamphor 5-monooxygenase1.14.15.10.444
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.444
4wsqKSAAP2-associated protein kinase 12.7.11.10.444
4xj43ATCyclic GMP-AMP synthase/0.444
1fff0Q4Gag-Pol polyprotein3.4.23.160.443
1fnnADPORC1-type DNA replication protein/0.443
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.443
1yb5NAPQuinone oxidoreductase1.6.5.50.443
1z1fSTLResveratrol synthase/0.443
1zys199Serine/threonine-protein kinase Chk12.7.11.10.443
2bkzSBCCyclin-dependent kinase 22.7.11.220.443
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.443
2p3c3TLProtease/0.443
2qocANPEphrin type-A receptor 32.7.10.10.443
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.443
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.443
3pe2E1BCasein kinase II subunit alpha2.7.11.10.443
3qlrNDPDihydrofolate reductase1.5.1.30.443
3sheI85MAP kinase-activated protein kinase 32.7.11.10.443
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.443
4fv9E71Mitogen-activated protein kinase 12.7.11.240.443
4i8zG08Gag-Pol polyprotein3.4.23.160.443
4ia7BIVVitamin D3 receptor A/0.443
4y93746Tyrosine-protein kinase/0.443
5aacVGHALK tyrosine kinase receptor2.7.10.10.443
5cp4CAMCamphor 5-monooxygenase1.14.15.10.443
1kzkJE2Gag-Pol polyprotein3.4.23.160.442
1m2pHNACasein kinase II subunit alpha2.7.11.10.442
1u3cFADCryptochrome-1/0.442
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.442
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.442
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.442
2p3b3TLV-1 PROTEASE protein/0.442
2p3b3TLV-1 protease/0.442
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.442
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.442
2xp2VGHALK tyrosine kinase receptor2.7.10.10.442
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.442
3at4CCKCasein kinase II subunit alpha2.7.11.10.442
3kytHC2Nuclear receptor ROR-gamma/0.442
3lpbNVBTyrosine-protein kinase JAK2/0.442
3t2zFADSulfide-quinone reductase/0.442
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.442
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4eok4SPCyclin-dependent kinase 22.7.11.220.442
4fob0USALK tyrosine kinase receptor2.7.10.10.442
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.442
4fv7E94Mitogen-activated protein kinase 12.7.11.240.442
4p8rNADGlyceraldehyde-3-phosphate dehydrogenase/0.442
4wkqIREEpidermal growth factor receptor2.7.10.10.442
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1t3r017Gag-Pol polyprotein3.4.23.160.441
1zemNADXylitol dehydrogenase/0.441
2b1pAIZMitogen-activated protein kinase 102.7.11.240.441
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.441
2c475IDCasein kinase I isoform gamma-2/0.441
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.441
2gtk208Peroxisome proliferator-activated receptor gamma/0.441
2itqITQEpidermal growth factor receptor2.7.10.10.441
2j0k4STFocal adhesion kinase 12.7.10.20.441
2ph5NADHomospermidine synthase/0.441
2pqzG0GGag-Pol polyprotein3.4.23.160.441
2wedPP6Penicillopepsin-13.4.23.200.441
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.441
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.441
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.441
3aw9NADNAD-dependent epimerase/dehydratase/0.441
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.441
3l0lHC3Nuclear receptor ROR-gamma/0.441
3ol5SAWCamphor 5-monooxygenase1.14.15.10.441
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.441
3u9eCOALmo1369 protein/0.441
3w2o03PEpidermal growth factor receptor2.7.10.10.441
3wrhCAMCamphor 5-monooxygenase1.14.15.10.441
3wrjCAMCamphor 5-monooxygenase1.14.15.10.441
3zep1NXTyrosine-protein kinase JAK32.7.10.20.441
4a6cQG9Gag-Pol polyprotein3.4.23.160.441
4bb432WEphrin type-B receptor 42.7.10.10.441
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.441
4erwSTUCyclin-dependent kinase 22.7.11.220.441
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.441
4ji91M3Tyrosine-protein kinase JAK2/0.441
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.441
4y8wSTRSteroid 21-hydroxylase/0.441
4yt5H4MH(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338/0.441
5dr6SKEAurora kinase A2.7.11.10.441
1fm4DXCMajor pollen allergen Bet v 1-L/0.440
1hosPHPGag-Pol polyprotein/0.440
1idb0DOGag-Pol polyprotein/0.440
1kl2FONSerine hydroxymethyltransferase/0.440
1nhhANPDNA mismatch repair protein MutL/0.440
1sguMK1Gag-Pol polyprotein3.4.23.160.440
1t86CAMCamphor 5-monooxygenase1.14.15.10.440
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.440
2ckeIQUDeath-associated protein kinase 2/0.440
2dfvNADL-threonine 3-dehydrogenase/0.440
2gekGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.440
2iw84SPCyclin-dependent kinase 22.7.11.220.440
2r5q1UNGag-Pol polyprotein/0.440
2vmyFFOSerine hydroxymethyltransferase/0.440
3bhtMFRCyclin-dependent kinase 22.7.11.220.440
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.440
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.440
3cyxROCGag-Pol polyprotein3.4.23.160.440
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3oy4017Gag-Pol polyprotein3.4.23.160.440
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.440
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4aotGW8Serine/threonine-protein kinase 102.7.11.10.440
4bcqTJFCyclin-dependent kinase 22.7.11.220.440
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.440
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.440
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4gt3ATPMitogen-activated protein kinase 12.7.11.240.440
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.440
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.440
4o701QKBromodomain-containing protein 4/0.440
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.440
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
5f8eSAHPossible transcriptional regulatory protein/0.440
5itzLOCTubulin beta-2B chain/0.440