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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2zff53UProthrombin3.4.21.5

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2zff53UProthrombin3.4.21.51.000
2zdv37UProthrombin3.4.21.50.926
2zgx29UProthrombin3.4.21.50.873
2zda32UProthrombin3.4.21.50.871
2zfr46UProthrombin3.4.21.50.813
2zhf49UProthrombin3.4.21.50.808
2zc922UProthrombin3.4.21.50.805
2zgb21UProthrombin3.4.21.50.802
2znk31UProthrombin3.4.21.50.784
2zg050UProthrombin3.4.21.50.782
3dux64UProthrombin3.4.21.50.782
3biu10UProthrombin3.4.21.50.780
3eq02TSProthrombin3.4.21.50.780
2zi224UProthrombin3.4.21.50.779
2zhq27UProthrombin3.4.21.50.775
2zfp19UProthrombin3.4.21.50.764
3qto10PProthrombin3.4.21.50.758
2zhe13UProthrombin3.4.21.50.754
2zf051UProthrombin3.4.21.50.753
4ax9N5NProthrombin3.4.21.50.752
3p1799PProthrombin3.4.21.50.748
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.731
4bamMM9Prothrombin3.4.21.50.713
2zfq45UProthrombin3.4.21.50.709
3biv11UProthrombin3.4.21.50.707
3dhk23UProthrombin3.4.21.50.706
3c27DKKProthrombin3.4.21.50.705
4bakM67Prothrombin3.4.21.50.705
2zhw12UProthrombin3.4.21.50.703
1ypjUIBProthrombin3.4.21.50.696
2r2mI50Prothrombin3.4.21.50.696
1d3dBZTProthrombin3.4.21.50.694
1c4uIH1Prothrombin3.4.21.50.689
4bahMELProthrombin3.4.21.50.688
4baoMVFProthrombin3.4.21.50.687
3qtv06PProthrombin3.4.21.50.681
1ypgUIRProthrombin3.4.21.50.679
7kmeACE_0BN_CHG_PRRProthrombin3.4.21.50.679
1ypeUIPProthrombin3.4.21.50.676
2anmCDOProthrombin3.4.21.50.673
3qwc98PProthrombin3.4.21.50.672
2v3oI26Prothrombin3.4.21.50.669
1d6w00RProthrombin3.4.21.50.667
1ae8AZLProthrombin3.4.21.50.666
2pksG44Prothrombin3.4.21.50.665
1ypmRA4Prothrombin3.4.21.50.659
1zrb062Prothrombin3.4.21.50.657
1sb1165Prothrombin3.4.21.50.654
1d4pBPPProthrombin3.4.21.50.649
2jh5895Prothrombin3.4.21.50.648
1mueCDDProthrombin3.4.21.50.645
1nm6L86Prothrombin3.4.21.50.644
2ziq26UProthrombin3.4.21.50.644
4banM6SProthrombin3.4.21.50.643
4baqM4ZProthrombin3.4.21.50.643
1k21IGNProthrombin3.4.21.50.639
1t4u81AProthrombin3.4.21.50.639
1d3pBT3Prothrombin3.4.21.50.637
1d9i00PProthrombin3.4.21.50.637
2bdyUNBProthrombin3.4.21.50.636
1xm1GAHProthrombin3.4.21.50.632
2uuj896Prothrombin3.4.21.50.630
1afeALZProthrombin3.4.21.50.629
4n3l2FNProthrombin3.4.21.50.628
2uuk897Prothrombin3.4.21.50.627
1t4v14AProthrombin3.4.21.50.625
1vzqSHYProthrombin3.4.21.50.624
1k22MELProthrombin3.4.21.50.622
1yplRA8Prothrombin3.4.21.50.617
1jwtBLIProthrombin3.4.21.50.613
1mu6CDAProthrombin3.4.21.50.613
2bvs2CEProthrombin3.4.21.50.611
2v3hI25Prothrombin3.4.21.50.610
2jh6894Prothrombin3.4.21.50.609
3c1kT15Prothrombin3.4.21.50.608
3utu1TSProthrombin3.4.21.50.607
4ayy9MXProthrombin3.4.21.50.607
1z71L17Prothrombin3.4.21.50.606
1c4yIH3Prothrombin3.4.21.50.599
1ypkCCRProthrombin3.4.21.50.597
4lxb7R9Prothrombin3.4.21.50.596
4e7r0NWProthrombin3.4.21.50.589
1oytFSNProthrombin3.4.21.50.585
2cn0F25Prothrombin3.4.21.50.585
2jh0701Prothrombin3.4.21.50.585
1o0d163Prothrombin3.4.21.50.584
1ta6177Prothrombin3.4.21.50.583
2cf9348Prothrombin3.4.21.50.583
1zgv501Prothrombin3.4.21.50.581
1c4vIH2Prothrombin3.4.21.50.577
1w7gMIUProthrombin3.4.21.50.573
2bxtC2DProthrombin3.4.21.50.573
4az29MUProthrombin3.4.21.50.568
2cf8ESHProthrombin3.4.21.50.567
2gdeSN3Prothrombin3.4.21.50.562
1zgi382Prothrombin3.4.21.50.559
1ghv120Prothrombin3.4.21.50.552
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.550
4rn615UProthrombin3.4.21.50.550
1a4wQWEProthrombin3.4.21.50.545
1nzq162Prothrombin3.4.21.50.545
1ta2176Prothrombin3.4.21.50.545
3f6891UProthrombin3.4.21.50.544
1uvsI11Prothrombin3.4.21.50.543
4hfp15UProthrombin3.4.21.50.530
1mu8CDBProthrombin3.4.21.50.528
4ayv9MQProthrombin3.4.21.50.526
4loy6XSProthrombin3.4.21.50.526
1riwOSCProthrombin3.4.21.50.522
5cmx0G6Prothrombin3.4.21.50.517
1ktsC24Prothrombin3.4.21.50.505
1gj5130Prothrombin3.4.21.50.502
1kvrNADUDP-glucose 4-epimerase5.1.3.20.495
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.494
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.494
2a2xNA9Prothrombin3.4.21.50.492
1umaIN2Prothrombin3.4.21.50.490
3qgf46FGenome polyprotein2.7.7.480.487
1c5nESIProthrombin3.4.21.50.486
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.485
5dozNDPJamJ/0.485
4kbyC2EStimulator of interferon genes protein/0.484
1c1uBAIProthrombin3.4.21.50.482
2nq8ZIDEnoyl-ACP reductase/0.482
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.482
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.481
4ey6GNTAcetylcholinesterase3.1.1.70.481
1sl3170Prothrombin3.4.21.50.480
1wqvPSMCoagulation factor VII3.4.21.210.480
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
1gj4132Prothrombin3.4.21.50.479
1x8lOXRRetinol dehydratase/0.479
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.479
2rqfJH3Hemolymph juvenile hormone binding protein/0.478
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.478
4q71FADBifunctional protein PutA/0.478
1bcuPRLProthrombin3.4.21.50.477
2wu4HBPAcetylcholinesterase3.1.1.70.477
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
3qdzPRO_ALA_PRO_ARGProthrombin3.4.21.50.477
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
3wqmB29Diterpene synthase3.1.7.80.476
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.476
2g1o2IGRenin3.4.23.150.475
2j83BATUlilysin3.4.240.474
4d89BXDBeta-secretase 13.4.23.460.474
2g1s4IGRenin3.4.23.150.473
2g8yNADHydroxycarboxylate dehydrogenase B/0.473
3eksCY9Actin-5C/0.473
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.473
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.472
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.472
1k7fIAVTryptophan synthase alpha chain/0.471
1pqc444Oxysterols receptor LXR-beta/0.471
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3oqfS51Renin3.4.23.150.471
3oqkS52Renin3.4.23.150.471
3vqsJT1Genome polyprotein/0.471
4k8s1QTBeta-secretase 13.4.23.460.471
4xguADPPutative pachytene checkpoint protein 2/0.471
5cyoGDPSeptin-9/0.471
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.470
3vyfVYFRenin3.4.23.150.470
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.470
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.470
2rlcCHDCholoylglycine hydrolase3.5.1.240.469
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.469
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.469
1txtCAAHMG-CoA synthase/0.468
3wtkTH4Acetylcholine-binding protein/0.468
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.467
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.467
4a802ANMajor pollen allergen Bet v 1-A/0.467
4fue7UPUrokinase-type plasminogen activator3.4.21.730.467
1pq944BOxysterols receptor LXR-beta/0.466
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.466
3ekuCY9Actin-5C/0.466
4a862ANMajor pollen allergen Bet v 1-A/0.466
1fmlRTLRetinol dehydratase/0.465
1ja0FADNADPH--cytochrome P450 reductase/0.465
2ejvNADL-threonine 3-dehydrogenase/0.465
2wf3ZY3Beta-secretase 13.4.23.460.465
2whqHI6Acetylcholinesterase3.1.1.70.465
3g70A5TRenin3.4.23.150.465
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.465
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.465
4frkDWDBeta-secretase 13.4.23.460.465
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.465
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.465
2g1r3IGRenin3.4.23.150.464
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.464
2xuiTZ5Acetylcholinesterase3.1.1.70.464
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1w0kADPATP synthase subunit alpha, mitochondrial/0.463
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.463
3iaaTYDCalG2/0.463
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.463
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.462
1upw444Oxysterols receptor LXR-beta/0.462
2g1n1IGRenin3.4.23.150.462
2g1y5IGRenin3.4.23.150.462
2gv8NDPThiol-specific monooxygenase1.14.130.462
4e2bFMNDehydrogenase/0.462
1rneC60Renin3.4.23.150.461
2cv2GSUGlutamate--tRNA ligase6.1.1.170.461
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
5irnADPNucleotide binding oligomerization domain containing 2/0.461
2jk6FADTrypanothione reductase/0.460
2qimZEAClass 10 plant pathogenesis-related protein/0.460
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.460
3adaNADSubunit alpha of sarocosine oxidase/0.460
3ensENSCoagulation factor X3.4.21.60.460
3f63GTXGlutathione transferase GST1-4/0.460
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.460
3vilSA0Beta-glucosidase/0.460
4a87NARMajor pollen allergen Bet v 1-A/0.460
4b1bFADThioredoxin reductase1.8.1.90.460
4c4oNADSADH/0.460
4gxs0YSGlutamate receptor 2/0.460
5ig2NADShort-chain dehydrogenase/reductase SDR/0.460
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1j9zFADNADPH--cytochrome P450 reductase/0.459
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1owe675Urokinase-type plasminogen activator3.4.21.730.459
1tl7ONMAdenylate cyclase type 2/0.459
1tl7ONMAdenylate cyclase type 5/0.459
1w34FADFerredoxin--NADP reductase1.18.1.20.459
2dvlFADAcyl-CoA dehydrogenase/0.459
2fhlBNIAvidin-related protein 4/5/0.459
4gh5NADShort-chain dehydrogenase/reductase SDR/0.459
4lzwTHMUridine phosphorylase/0.459
4oztP1AEcdysone receptor, putative/0.459
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.458
1x7hNDPPutative ketoacyl reductase1.3.10.458
2il2LIXRenin3.4.23.150.458
2pg0FADAcyl-CoA dehydrogenase/0.458
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.458
2xuoTZ4Acetylcholinesterase3.1.1.70.458
2xyd3ESAngiotensin-converting enzyme3.2.10.458
4bttVYRCoagulation factor X3.4.21.60.458
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.458
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.458
4epq0RRPoly(ADP-ribose) glycohydrolase/0.458
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.458
4x28FDAAcyl-CoA dehydrogenase FadE26/0.458
4x28FDAAcyl-CoA dehydrogenase FadE27/0.458
2znnS44Peroxisome proliferator-activated receptor alpha/0.457
3c15FOKAdenylate cyclase type 2/0.457
3c15FOKAdenylate cyclase type 5/0.457
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3gwfNAPCyclohexanone monooxygenase/0.457
3q7fED2Uncharacterized protein/0.457
4bfxZVXPantothenate kinase2.7.1.330.457
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.457
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.457
1q84TZ4Acetylcholinesterase3.1.1.70.456
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.456
2watCOAFatty acid synthase subunit alpha2.3.1.860.456
4an4DUDPutative glycosyl transferase/0.456
4ejmNAPPutative zinc-binding dehydrogenase/0.456
4jjiNADAlcohol dehydrogenase class-3/0.456
4ku5DCC3-oxoacyl-[ACP] synthase III/0.456
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.455
1u1f183Uridine phosphorylase2.4.2.30.455
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.455
2bjfDXCCholoylglycine hydrolase3.5.1.240.455
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.455
2fzeAPRAlcohol dehydrogenase class-31.1.1.10.455
2h21SAMRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.455
2j3qTFLAcetylcholinesterase3.1.1.70.455
2uxoTACHTH-type transcriptional regulator TtgR/0.455
2zshGA3Gibberellin receptor GID1A30.455
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.455
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1knrFADL-aspartate oxidase1.4.3.160.454
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.454
2c4fGILCoagulation factor VII3.4.21.210.454
2ignFADPyranose 2-oxidase/0.454
2po7CHDFerrochelatase, mitochondrial4.99.1.10.454
3f03FMNPentaerythritol tetranitrate reductase/0.454
3fbuCOAAcetyltransferase, GNAT family/0.454
3mauEXTPutative sphingosine-1-phosphate lyase/0.454
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.454
4r81FMNPredicted NADH dehydrogenase/0.454
1bil0IURenin3.4.23.150.453
1joaFADNADH peroxidase1.11.1.10.453
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.453
2vyqFADFerredoxin--NADP reductase1.18.1.20.453
2wf1ZY1Beta-secretase 13.4.23.460.453
2znpK55Peroxisome proliferator-activated receptor delta/0.453
3phiNDPShikimate dehydrogenase (NADP(+))/0.453
3w8eNAD3-hydroxybutyrate dehydrogenase/0.453
4cdmFO1Deoxyribodipyrimidine photolyase/0.453
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.453
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
2owuSAHDiphthine synthase/0.452
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.452
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.452
3fr28CAFatty acid-binding protein, adipocyte/0.452
3nxxNDPDihydrofolate reductase1.5.1.30.452
4cf6CBDNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
1mrqSTRAldo-keto reductase family 1 member C1/0.451
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.451
1udaUFGUDP-glucose 4-epimerase5.1.3.20.451
1xs7MMIBeta-secretase 13.4.23.460.451
2b8l5HABeta-secretase 13.4.23.460.451
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.451
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.451
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.451
2owkSAHDiphthine synthase/0.451
2xuhTZ4Acetylcholinesterase3.1.1.70.451
2zbaZBATrichothecene 3-O-acetyltransferase/0.451
3dxmN24Actin-related protein 3/0.451
3g6zA7TRenin3.4.23.150.451
3qt62P0Mevalonate diphosphate decarboxylase/0.451
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.451
4uthFMNXenobiotic reductase/0.451
4yfy0FXVioF/0.451
5ej7TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.451
1i3mUD1UDP-glucose 4-epimerase/0.450
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.450
2fzwNADAlcohol dehydrogenase class-31.1.1.10.450
2uxhQUEHTH-type transcriptional regulator TtgR/0.450
3cow52HPantothenate synthetase6.3.2.10.450
3hlwCE3Beta-lactamase/0.450
3k1wBFXRenin3.4.23.150.450
3kpbSAMUncharacterized protein MJ0100/0.450
4m9aFDAAcyl-CoA dehydrogenase/0.450
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.450
1cf3FADGlucose oxidase1.1.3.40.449
1fvpFMANon-fluorescent flavoprotein/0.449
1oc1ASVIsopenicillin N synthase1.21.3.10.449
1u1gBBBUridine phosphorylase2.4.2.30.449
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.449
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.449
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3lqfNADGalactitol dehydrogenase/0.449
3own3OWRenin3.4.23.150.449
3p84FMNPentaerythritol tetranitrate reductase/0.449
3v0p4GWHisto-blood group ABO system transferase/0.449
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.449
4dbzNDPPutative ketoacyl reductase1.3.10.449
4e5yNDPGDP-L-fucose synthase1.1.1.2710.449
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.449
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.448
1lnmDTXBilin-binding protein/0.448
1zeoC01Peroxisome proliferator-activated receptor gamma/0.448
2gywOBIAcetylcholinesterase3.1.1.70.448
2lbaCHOFatty acid binding protein 6/0.448
2o12FMNChorismate synthase/0.448
2pchSAHDiphthine synthase/0.448
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.448
3fr5I4AFatty acid-binding protein, adipocyte/0.448
3lkhLT6Genome polyprotein2.7.7.480.448
3qe2FMNNADPH--cytochrome P450 reductase/0.448
3rsv3RSBeta-secretase 13.4.23.460.448
4e2yJHZMethyltransferase/0.448
1a5bIGPTryptophan synthase alpha chain/0.447
1eq2NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.447
1fm4DXCMajor pollen allergen Bet v 1-L/0.447
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.447
1vf3GDNGlutathione S-transferase 32.5.1.180.447
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.447
2ehlSAHDiphthine synthase/0.447
2eleSAHDiphthine synthase/0.447
2ptfFMNUncharacterized protein MTH_863/0.447
3c35KAIGlutamate receptor ionotropic, kainate 1/0.447
3cneFMNPutative protease I/0.447
3drcMTXDihydrofolate reductase1.5.1.30.447
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.447
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.447
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.447
3tp0FO5HTH-type transcriptional regulator EthR/0.447
4b0cC9H3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase4.2.1.590.447
4c73TLH3-oxoacyl-ACP synthase/0.447
4kwcSAHMethyltransferase domain family/0.447
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.447
1mvtDTMDihydrofolate reductase1.5.1.30.446
1rfuADPPyridoxal kinase2.7.1.350.446
2ag1TPPBenzaldehyde lyase/0.446
2ejkSAHDiphthine synthase/0.446
2emrSAHDiphthine synthase/0.446
2g20L1ARenin3.4.23.150.446
2xupTZ5Acetylcholinesterase3.1.1.70.446
2ylrNAPPhenylacetone monooxygenase1.14.13.920.446
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.446
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.446
3qvrFADGlucose oxidase1.1.3.40.446
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.446
4p9dTMPDeoxycytidylate deaminase/0.446
4zm6ACON-acetyl-beta-D glucosaminidase/0.446
1culFOKAdenylate cyclase type 2/0.445
1culFOKAdenylate cyclase type 5/0.445
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1v35NAIEnoyl-ACP reductase/0.445
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.445
2egbSAHDiphthine synthase/0.445
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.445
2yxuATPPyridoxal kinase2.7.1.350.445
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.445
4arbC57Acetylcholinesterase3.1.1.70.445
4jx1CAHCamphor 5-monooxygenase1.14.15.10.445
4jzr4JREgl nine homolog 1/0.445
4m4922YL-lactate dehydrogenase A chain1.1.1.270.445
1qoqIGPTryptophan synthase alpha chain/0.444
2g247IGRenin3.4.23.150.444
2ha6SCKAcetylcholinesterase3.1.1.70.444
2ifaFMNUncharacterized protein/0.444
2z6rSAHDiphthine synthase/0.444
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.444
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.444
3hk1B64Fatty acid-binding protein, adipocyte/0.444
3oadLPORenin3.4.23.150.444
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.444
4bftZVTPantothenate kinase2.7.1.330.444
4bfwZVWPantothenate kinase2.7.1.330.444
4bj9UHBTankyrase-22.4.2.300.444
4dpf0LGBeta-secretase 13.4.23.460.444
4h6pFMNChromate reductase/0.444
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.444
4jqaID8Aldo-keto reductase family 1 member C2/0.444
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.444
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.444
5cflC2EStimulator of interferon genes protein/0.444
1typFADTrypanothione reductase1.8.1.120.443
2bu9HFVIsopenicillin N synthase1.21.3.10.443
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2hdjNDPAldo-keto reductase family 1 member C2/0.443
2nr4FMNConserved protein/0.443
2vkeTACTetracycline repressor protein class D/0.443
2x96RX3Angiotensin-converting enzyme3.4.15.10.443
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
2zevIPEGeranylgeranyl pyrophosphate synthase/0.443
3ai0PNWBeta-glucosidase/0.443
3b6pTMPThree-prime repair exonuclease 13.1.11.20.443
3h3t16HCollagen type IV alpha-3-binding protein/0.443
3ioeA7DPantothenate synthetase6.3.2.10.443
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.443
3v0o4GWHisto-blood group ABO system transferase/0.443
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.443
4b1hAR6Poly(ADP-ribose) glycohydrolase3.2.1.1430.443
4c72TLG3-oxoacyl-ACP synthase/0.443
4hh4SAHCcbJ/0.443
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.443
1a2nTETUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.442
1vceSAHDiphthine synthase/0.442
2cmoM1LGlutamate receptor 2/0.442
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.442
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.442
2gjlFMNNitronate monooxygenase1.13.12.160.442
2iqgF2IBeta-secretase 13.4.23.460.442
2vbdV10Isopenicillin N synthase1.21.3.10.442
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.442
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.442
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.442
3fhxPXLPyridoxal kinase2.7.1.350.442
3lqsPSZD-alanine aminotransferase2.6.1.210.442
3pndFADFAD:protein FMN transferase/0.442
3s5wNAPL-ornithine N(5)-monooxygenase/0.442
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
4iji99TGlutathione S-transferase-like protein YibF/0.442
5jlaNADPutative short-chain dehydrogenase/reductase/0.442
1amoFADNADPH--cytochrome P450 reductase/0.441
1h22E10Acetylcholinesterase3.1.1.70.441
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.441
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.441
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1r2jFADFkbI/0.441
1vbiNADMalate/L-lactate dehydrogenase family protein/0.441
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.441
2g226IGRenin3.4.23.150.441
2gesCOKPantothenate kinase2.7.1.330.441
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.441
2oegUPGUDP-glucose pyrophosphorylase/0.441
2xukTZ5Acetylcholinesterase3.1.1.70.441
2xvhNAPPutative flavin-containing monooxygenase/0.441
2zt5B4PGlycine--tRNA ligase/0.441
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.441
3g11P9C3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.441
3ha5SFGHydroxymycolate synthase MmaA42.1.10.441
3r95ACOMccE protein/0.441
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.441
3wagTYDGlycosyltransferase/0.441
4hy6FJ1Heat shock protein HSP 90-alpha/0.441
4mihFADPyranose 2-oxidase1.1.3.100.441
5c3aURMHisto-blood group ABO system transferase/0.441
1g63FMNEpidermin decarboxylase4.1.10.440
1s63778Protein farnesyltransferase subunit beta2.5.1.580.440
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.440
1yhjR6CPyridoxal kinase2.7.1.350.440
2cndFADNitrate reductase [NADH]1.7.1.10.440
2ej2PPEBranched-chain amino acid aminotransferase (IlvE)/0.440
2eniSAHDiphthine synthase/0.440
2ikuLIYRenin3.4.23.150.440
2iviACWIsopenicillin N synthase1.21.3.10.440
2iyaZIOOleandomycin glycosyltransferase/0.440
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.440
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.440
2pncCLUPrimary amine oxidase, liver isozyme/0.440
2v5uFMNFlavodoxin/0.440
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.440
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.440
3in6FMNUncharacterized protein/0.440
3mo0SAHHistone-lysine N-methyltransferase EHMT1/0.440
3zm62GNUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.440
4bfvZVVPantothenate kinase2.7.1.330.440
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.440
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.440
4fsl0VBBeta-secretase 13.4.23.460.440
4gapNADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.440
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.440