Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2uvy | GVI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2uvy | GVI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 1.000 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.640 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.634 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.601 | |
| 2uw7 | GVP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.593 | |
| 2uw6 | GVO | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.589 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.583 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.578 | |
| 2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.574 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.563 | |
| 1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.562 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.557 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.557 | |
| 2uw5 | GVN | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.550 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.539 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.532 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.527 | |
| 3ow3 | SMY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.526 | |
| 2vo0 | M03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.521 | |
| 2vnw | M01 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.520 | |
| 3nf7 | CIW | Gag-Pol polyprotein | / | 0.519 | |
| 2vo6 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.514 | |
| 4cjw | CBJ | Integrase | / | 0.512 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.510 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.507 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.503 | |
| 2vo3 | M04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.500 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.499 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.499 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.499 | |
| 3zo1 | SIJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.499 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.499 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.496 | |
| 1ppj | ANY | Cytochrome b | / | 0.495 | |
| 2gnf | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.495 | |
| 3nfa | CBJ | Gag-Pol polyprotein | / | 0.495 | |
| 1jbp | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.493 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.493 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.493 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 2gnl | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.492 | |
| 2uw4 | L15 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.492 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.492 | |
| 2uvz | GVJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.491 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
| 3zo4 | QWI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.490 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.489 | |
| 1osv | CHC | Bile acid receptor | / | 0.488 | |
| 2uzv | SS5 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.488 | |
| 4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.488 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.486 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.485 | |
| 4iwc | 1GV | Estrogen receptor | / | 0.485 | |
| 1eio | GCH | Gastrotropin | / | 0.484 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.484 | |
| 5doz | NDP | JamJ | / | 0.484 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.483 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.483 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.483 | |
| 3dtc | VIN | Mitogen-activated protein kinase kinase kinase 9 | 2.7.11.25 | 0.482 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.481 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.480 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.478 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.477 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.477 | |
| 3qtr | X36 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.476 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.475 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.475 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.475 | |
| 3qfv | NM7 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.475 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.474 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.473 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.472 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.472 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.472 | |
| 3bgi | SAH | Thiopurine S-methyltransferase | 2.1.1.67 | 0.472 | |
| 3fmm | XI2 | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 3tku | M77 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.472 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.472 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.471 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.471 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.471 | |
| 1q8t | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.470 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.470 | |
| 4o7u | THF | Thymidylate synthase | / | 0.470 | |
| 4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.470 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.469 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.469 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.468 | |
| 4kdr | SAH | Ubiquinone biosynthesis O-methyltransferase | / | 0.468 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.467 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.467 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.467 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.467 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.467 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.467 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.466 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.466 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.466 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.466 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.465 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.465 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.465 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.464 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.464 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.464 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.464 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2bxo | OPB | Serum albumin | / | 0.463 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.463 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.463 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.463 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.463 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.463 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.463 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.462 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.462 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.462 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.462 | |
| 4fx3 | 60K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.462 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.461 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3qzg | X67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.461 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.461 | |
| 4gv1 | 0XZ | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.461 | |
| 5e8j | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.461 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.460 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.460 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.460 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.460 | |
| 3p9k | SAH | Caffeic acid O-methyltransferase | / | 0.460 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.460 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.460 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.460 | |
| 4ez3 | 0S0 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.460 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.460 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 4y6n | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.460 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2za0 | MGI | Lactoylglutathione lyase | 4.4.1.5 | 0.459 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.459 | |
| 3dmh | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.459 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.459 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.459 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.459 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.458 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.458 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.458 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.458 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.458 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.458 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.458 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.458 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.457 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.457 | |
| 2ibz | SMA | Cytochrome b | / | 0.457 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.457 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.457 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.457 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.457 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.457 | |
| 4pyo | SAH | Catechol O-methyltransferase | 2.1.1.6 | 0.457 | |
| 4pyt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.457 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.456 | |
| 2owv | SAH | Diphthine synthase | / | 0.456 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.456 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3ncz | 3NC | Rho-associated protein kinase 1 | 2.7.11.1 | 0.456 | |
| 3oht | 1N1 | Mitogen-activated protein kinase | / | 0.456 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 3vew | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.456 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.456 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.456 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.456 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.456 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.456 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.456 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.456 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.455 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.455 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.455 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.455 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.455 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.455 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.455 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.455 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3qtw | X3A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.455 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.455 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4iwx | ADP | Ribosomal protein S6--L-glutamate ligase | / | 0.455 | |
| 4l8u | 9AZ | Serum albumin | / | 0.455 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.455 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.454 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 1v1k | 3FP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.454 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.454 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.454 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.454 | |
| 2wd4 | TBV | Ascorbate peroxidase | / | 0.454 | |
| 3aba | FLI | Cytochrome P450 | / | 0.454 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.454 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.454 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.454 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.454 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 4f6s | 0SQ | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.454 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.454 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.454 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.453 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.453 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.453 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.453 | |
| 4v37 | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.453 | |
| 4y9x | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.453 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.453 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.453 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.452 | |
| 1vce | SAH | Diphthine synthase | / | 0.452 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.452 | |
| 3ds6 | A17 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3lu8 | IQX | Serum albumin | / | 0.452 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.452 | |
| 3unk | 0BY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.451 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.451 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.451 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.451 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.451 | |
| 2x23 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.451 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.451 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.451 | |
| 3vf2 | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.451 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.451 | |
| 3zln | H0Y | Bcl-2-like protein 1 | / | 0.451 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.451 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.451 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.451 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.451 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.451 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.451 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.451 | |
| 1ict | T44 | Transthyretin | / | 0.450 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.450 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.450 | |
| 2bx8 | AZQ | Serum albumin | / | 0.450 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.450 | |
| 3lpf | Z77 | Beta-glucuronidase | 3.2.1.31 | 0.450 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.450 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.450 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.450 | |
| 4l9z | COA | L-malyl-CoA/beta-methylmalyl-CoA lyase | 4.1.3.24 | 0.450 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 4zca | ADP | Kinesin-like protein KIF11 | / | 0.450 | |
| 1q4x | G24 | Thyroid hormone receptor beta | / | 0.449 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.449 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.449 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.449 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.449 | |
| 2r3y | VAL_TYR_TRP_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.449 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.449 | |
| 3dfc | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.449 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.449 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3up3 | XCA | aceDAF-12 | / | 0.449 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.449 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.449 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.449 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.449 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.449 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.448 | |
| 1dxr | MST | Reaction center protein L chain | / | 0.448 | |
| 1gqy | ACP | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.448 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.448 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.448 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.448 | |
| 2r5t | ANP | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.448 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.448 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.448 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.448 | |
| 3zos | 0LI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.448 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.448 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.448 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.448 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.447 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.447 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.447 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.447 | |
| 1zq9 | SAM | Probable dimethyladenosine transferase | / | 0.447 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.447 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.447 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.447 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.447 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.447 | |
| 3bx5 | 304 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3il4 | ACO | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.447 | |
| 3nyn | SGV | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.447 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3qn8 | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.447 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.447 | |
| 4ceq | QCH | Integrase | / | 0.447 | |
| 4dm6 | TTB | Retinoic acid receptor beta | / | 0.447 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.447 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.447 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.447 | |
| 1q99 | ANP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.446 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.446 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.446 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.446 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.446 | |
| 3iup | NDP | Possible NADH oxidoreductase | / | 0.446 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.446 | |
| 3qwk | X62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.446 | |
| 3rgf | BAX | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.446 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.446 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.446 | |
| 4an2 | EUI | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.446 | |
| 4f9b | 0SY | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.446 | |
| 4fti | H7K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.446 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.446 | |
| 4i3w | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.446 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.446 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.446 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.446 | |
| 4y8v | ADP | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.446 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.446 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1egc | CO8 | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.445 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2dji | FAD | Pyruvate oxidase | / | 0.445 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.445 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 2wlg | SOP | Polysialic acid O-acetyltransferase | / | 0.445 | |
| 2y6d | TQJ | Matrilysin | 3.4.24.23 | 0.445 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 3gc8 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.445 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.445 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.445 | |
| 3qbw | ADP | Anhydro-N-acetylmuramic acid kinase | / | 0.445 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.445 | |
| 4agc | AXI | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.445 | |
| 4dkv | 0KW | Envelope glycoprotein gp160 | / | 0.445 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.445 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.445 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.445 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.445 | |
| 6upj | NIU | Gag-Pol polyprotein | / | 0.445 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.444 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1jut | LYD | Thymidylate synthase | / | 0.444 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.444 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.444 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.444 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.444 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.444 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2w1h | L0F | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.444 | |
| 3acw | 651 | Dehydrosqualene synthase | / | 0.444 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.444 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.444 | |
| 3lu6 | IMX | Serum albumin | / | 0.444 | |
| 3nie | ANP | Mitogen-activated protein kinase | / | 0.444 | |
| 3nu5 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.444 | |
| 3rjc | 06Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.444 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 3v04 | V04 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.444 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.444 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.444 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.444 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.444 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.444 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.443 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.443 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.443 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.443 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.443 | |
| 1sqv | UHD | Cytochrome b | / | 0.443 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.443 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 3bhr | THG | Thymidylate synthase | / | 0.443 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.443 | |
| 3k9v | CPS | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | / | 0.443 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.443 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.443 | |
| 3s0o | 50Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3stx | BKA | Methylketone synthase I | / | 0.443 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.443 | |
| 4ii5 | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.443 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.443 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.442 | |
| 1fml | RTL | Retinol dehydratase | / | 0.442 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.442 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.442 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.442 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.442 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.442 | |
| 2dsh | SAH | Diphthine synthase | / | 0.442 | |
| 2g37 | FAD | Proline dehydrogenase | / | 0.442 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.442 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 2qjp | ANJ | Cytochrome b | / | 0.442 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.442 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 2ydf | IO3 | Serum albumin | / | 0.442 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.442 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3f46 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.442 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.442 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3r3d | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.442 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.442 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.442 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.442 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.442 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.442 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.442 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 1an5 | CB3 | Thymidylate synthase | / | 0.441 | |
| 1ayp | INB | Phospholipase A2, membrane associated | / | 0.441 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.441 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.441 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.441 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.441 | |
| 1rrm | APR | Lactaldehyde reductase | 1.1.1.77 | 0.441 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.441 | |
| 1wma | AB3 | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.441 | |
| 1zsn | TN2 | Enoyl-ACP reductase | / | 0.441 | |
| 2bu7 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.441 | |
| 2fxd | DR7 | Pol polyprotein | / | 0.441 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.441 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.441 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.441 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.441 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.441 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.441 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.441 | |
| 4b1f | KRH | Glutamate racemase | / | 0.441 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4eb4 | D16 | Thymidylate synthase | 2.1.1.45 | 0.441 | |
| 4fsq | HK3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4iwy | ADP | Ribosomal protein S6--L-glutamate ligase | / | 0.441 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 4y6g | F6F | Tryptophan synthase alpha chain | / | 0.441 | |
| 5c7h | NDP | Putative oxidoreductase | / | 0.441 | |
| 5cae | COA | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial | 6.2.1.4 | 0.441 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.441 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.440 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 1o6r | R19 | Squalene--hopene cyclase | 4.2.1.129 | 0.440 | |
| 1ysx | 4EB | Serum albumin | / | 0.440 | |
| 2ayl | FLP | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.440 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.440 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.440 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3fzs | B96 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.440 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.440 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.440 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.440 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3r9o | Z71 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3up0 | D7S | aceDAF-12 | / | 0.440 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.440 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.440 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4ict | 1ED | Mycocyclosin synthase | 1.14.21.9 | 0.440 | |
| 4inb | 1F6 | Gag protein | / | 0.440 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.440 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.440 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.440 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4xwt | U5P | Ribonuclease J | / | 0.440 | |
| 5dp2 | NAP | CurF | / | 0.440 |