sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2q93 | B21 | Methionine aminopeptidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2q93 | B21 | Methionine aminopeptidase | / | 1.000 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.838 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.719 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.707 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.692 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.686 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.671 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.669 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.663 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.663 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.641 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.630 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.629 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.618 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.609 | |
| 1xnz | FCD | Methionine aminopeptidase | / | 0.601 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.600 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.597 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.583 | |
| 4fli | Y16 | Methionine aminopeptidase 1 | / | 0.582 | |
| 2gg3 | U13 | Methionine aminopeptidase | / | 0.574 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.569 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.568 | |
| 2nq7 | HM5 | Methionine aminopeptidase 1 | / | 0.563 | |
| 2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.562 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.555 | |
| 4flj | Y08 | Methionine aminopeptidase 1 | / | 0.555 | |
| 4hxx | 1AY | Methionine aminopeptidase 1 | / | 0.550 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.549 | |
| 4iku | SHX | Methionine aminopeptidase 1 | / | 0.548 | |
| 4fll | YZ6 | Methionine aminopeptidase 1 | / | 0.547 | |
| 3pkc | Y08 | Methionine aminopeptidase 2 | / | 0.522 | |
| 4ikr | PVP | Methionine aminopeptidase 1 | / | 0.519 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.513 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.504 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.504 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.502 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.498 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.494 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.491 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.489 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.489 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.488 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.488 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.486 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.484 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.484 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.484 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.483 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 3mo0 | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.483 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.480 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.479 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.479 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.478 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.478 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.477 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.477 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.476 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.476 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.476 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.476 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.475 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.475 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.474 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.474 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.473 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.473 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.473 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.473 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.472 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.472 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.471 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.471 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.471 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.470 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.470 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.470 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.469 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.469 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.469 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.469 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.469 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.468 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.468 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.467 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.467 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.467 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.466 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.466 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.465 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.465 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.465 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.464 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.464 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.464 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.464 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.462 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.462 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.461 | |
| 3ccb | B2Y | Dipeptidyl peptidase 4 | / | 0.461 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.461 | |
| 4q7f | 3D1 | Uncharacterized protein | / | 0.461 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.460 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.460 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.459 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.459 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.459 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.459 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.459 | |
| 4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.459 | |
| 3dz6 | M8E | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.458 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.458 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.458 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.457 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.457 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.457 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.456 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.456 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.456 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 4lxl | PD2 | Lysine-specific demethylase 4B | 1.14.11 | 0.456 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.455 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.455 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.455 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.455 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.455 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.455 | |
| 4dxl | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.455 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.455 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.455 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.454 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.454 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.454 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.454 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.454 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.454 | |
| 4a7z | AY9 | Aldos-2-ulose dehydratase | / | 0.454 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.453 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.453 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.453 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3gf4 | UPG | UDP-galactopyranose mutase | 5.4.99.9 | 0.453 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.452 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.452 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.452 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.452 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.452 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.452 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.452 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.452 | |
| 1gm9 | SOX | Penicillin G acylase | 3.5.1.11 | 0.451 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.451 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.451 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.450 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.450 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.450 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.450 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.450 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.450 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.450 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.450 | |
| 1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.449 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1m9h | NAD | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.449 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.449 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.449 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.449 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.449 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.449 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.448 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.448 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.448 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.448 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.448 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.448 | |
| 2vbq | BSJ | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.448 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.448 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.447 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.447 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.447 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.447 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.446 | |
| 3e6e | DCS | Alanine racemase | / | 0.446 | |
| 3fvu | IAC | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.446 | |
| 3kyb | FMN | UDP-galactopyranose mutase | 5.4.99.9 | 0.446 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.446 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.446 | |
| 4nv1 | TYD | Formyl transferase | / | 0.446 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.445 | |
| 2a3c | PNX | Endochitinase B1 | 3.2.1.14 | 0.445 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.445 | |
| 3frk | TQP | QdtB | / | 0.445 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.445 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.445 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.445 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.444 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.444 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.444 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.444 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.444 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.444 | |
| 4to1 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 5jhn | SAM | Histone-lysine N-methyltransferase EHMT2 | / | 0.444 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.443 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.443 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.443 | |
| 1xry | BES | Bacterial leucyl aminopeptidase | 3.4.11.10 | 0.443 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.443 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.443 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.443 | |
| 4uth | FMN | Xenobiotic reductase | / | 0.443 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.443 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.443 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2onf | COA | Uncharacterized protein | / | 0.442 | |
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.442 | |
| 3g5i | DNB | Pyrimidine-specific ribonucleoside hydrolase RihA | / | 0.442 | |
| 3rib | SAH | N-lysine methyltransferase SMYD2 | / | 0.442 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.442 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.442 | |
| 4e2y | JHZ | Methyltransferase | / | 0.442 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.442 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.442 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.441 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.441 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.441 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4kn1 | 04J | Folate receptor beta | / | 0.441 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.441 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.441 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.440 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.440 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.440 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.440 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.440 | |
| 2zue | ANP | Arginine--tRNA ligase | 6.1.1.19 | 0.440 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.440 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.440 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 |