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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1j9gFMNFlavodoxin

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1j9gFMNFlavodoxin/1.000
1fx1FMNFlavodoxin/0.628
1wsbFMNFlavodoxin/0.604
1akwFMNFlavodoxin/0.598
1azlFMNFlavodoxin/0.597
4fx2FMNFlavodoxin/0.596
2fx2FMNFlavodoxin/0.594
3f6rFMNFlavodoxin/0.583
5tgzFMNCannabinoid receptor 1/0.574
1akrFMNFlavodoxin/0.571
1j8qFMNFlavodoxin/0.569
3f90FMNFlavodoxin/0.564
4y7cFMNNADPH--cytochrome P450 reductase/0.560
3kapFMNFlavodoxin/0.559
3kaqFMNFlavodoxin/0.552
1c7fFMNFlavodoxin/0.549
3f6sFMNFlavodoxin/0.548
1bu5RBFFlavodoxin/0.547
1xyvFMNFlavodoxin/0.543
4oxxFMNCindoxin/0.543
5fx2FMNFlavodoxin/0.540
1akuFMNFlavodoxin/0.539
1xyyFMNFlavodoxin/0.534
5xraFMNCannabinoid receptor 1/0.528
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.522
3ojxFMNNADPH--cytochrome P450 reductase/0.519
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.517
1ofvFMNFlavodoxin/0.508
2v5uFMNFlavodoxin/0.499
1cznFMNFlavodoxin/0.494
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.494
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.493
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.492
2mokFMNFlavodoxin 1/0.491
1ahnFMNFlavodoxin 1/0.490
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.490
2po3T4K4-dehydrase/0.489
3ndjJHZMethyltransferase/0.489
2fcrFMNFlavodoxin/0.488
3c1kT15Prothrombin3.4.21.50.488
3zc3FADFerredoxin--NADP reductase1.18.1.20.488
1jwtBLIProthrombin3.4.21.50.487
2g8yNADHydroxycarboxylate dehydrogenase B/0.485
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.485
1f20FADNitric oxide synthase, brain1.14.13.390.484
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.484
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.484
3ai0PNWBeta-glucosidase/0.480
5a4vQUEGlutathione S-transferase F22.5.1.180.480
3aosJH2Hemolymph juvenile hormone binding protein/0.479
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.479
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.479
2xlpNAPPutative flavin-containing monooxygenase/0.478
3fhxPXLPyridoxal kinase2.7.1.350.478
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.478
3hr4FMNNitric oxide synthase, inducible1.14.13.390.477
4e32DWNMethyltransferase/0.477
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.476
4b1jA1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.476
4b63NAPL-ornithine N(5)-monooxygenase/0.475
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.475
3ihgVAKAklavinone 12-hydroxylase RdmE/0.474
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.474
2aotSAHHistamine N-methyltransferase2.1.1.80.473
2pncCLUPrimary amine oxidase, liver isozyme/0.473
3ojwFMNNADPH--cytochrome P450 reductase/0.473
4fse0VABeta-secretase 13.4.23.460.473
1ja0FMNNADPH--cytochrome P450 reductase/0.472
1nzq162Prothrombin3.4.21.50.472
1obnASVIsopenicillin N synthase1.21.3.10.472
2c20NADUDP-glucose 4-epimerase/0.472
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.472
3p62FMNPentaerythritol tetranitrate reductase/0.472
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.472
1pq944BOxysterols receptor LXR-beta/0.471
3fktSIIBeta-secretase 13.4.23.460.471
3qe2FMNNADPH--cytochrome P450 reductase/0.471
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.471
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.471
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.470
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.470
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.469
1tllFMNNitric oxide synthase, brain1.14.13.390.469
2gv8NDPThiol-specific monooxygenase1.14.130.469
1d6w00RProthrombin3.4.21.50.468
1h42FADFerredoxin--NADP reductase1.18.1.20.468
2c9bPUG6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
2ztsADPUncharacterized protein/0.468
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.468
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.468
4d965PAD-cysteine desulfhydrase/0.468
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
1ykgFMNSulfite reductase [NADPH] flavoprotein alpha-component/0.467
2bn4FMNNADPH--cytochrome P450 reductase/0.467
3b7dCNIGlutamate receptor 2/0.467
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3esyFMNFlavodoxin/0.467
3zv7NHGAcetylcholinesterase3.1.1.70.467
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.466
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.466
3udj092Beta-secretase 13.4.23.460.466
1ja0FADNADPH--cytochrome P450 reductase/0.465
2w6cBM4Acetylcholinesterase3.1.1.70.465
3fhxPLPPyridoxal kinase2.7.1.350.465
3q9bB3NAcetylpolyamine amidohydrolase/0.465
1gky5GPGuanylate kinase2.7.4.80.464
2bf4FADNADPH--cytochrome P450 reductase/0.464
2geuCOKPantothenate kinase2.7.1.330.464
2pb1NFGGlucan 1,3-beta-glucosidase/0.464
2vbpVB1Isopenicillin N synthase1.21.3.10.464
3eufBAUUridine phosphorylase 1/0.464
3irhDTPHD domain protein/0.464
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.464
1cnfFADNitrate reductase [NADH]1.7.1.10.463
1nm6L86Prothrombin3.4.21.50.463
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.463
3fznD7KBenzoylformate decarboxylase4.1.1.70.463
3gr8FMNNADPH dehydrogenase/0.463
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.463
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.463
1h22E10Acetylcholinesterase3.1.1.70.462
1j9zFMNNADPH--cytochrome P450 reductase/0.462
1xs7MMIBeta-secretase 13.4.23.460.462
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.462
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.462
3c27DKKProthrombin3.4.21.50.462
3qwc98PProthrombin3.4.21.50.462
4twnB96Ephrin type-A receptor 32.7.10.10.462
1c4yIH3Prothrombin3.4.21.50.461
1jqdSAHHistamine N-methyltransferase2.1.1.80.461
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.461
2bpoFADNADPH--cytochrome P450 reductase/0.461
2jb4A14Isopenicillin N synthase1.21.3.10.461
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.461
3qfrFMNNADPH--cytochrome P450 reductase/0.461
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.461
4uugPXGBranched-chain amino acid aminotransferase, putative/0.461
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.460
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.460
1oc1ASVIsopenicillin N synthase1.21.3.10.460
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.460
5xr8FMNCannabinoid receptor 1/0.460
1a9cGTPGTP cyclohydrolase 13.5.4.160.459
1pqc444Oxysterols receptor LXR-beta/0.459
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.459
3v2uATPProtein GAL3/0.459
3wqtANPCell division protein FtsA/0.459
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.459
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.459
5choFADFlavin reductase/0.459
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.458
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.458
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.458
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.458
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.458
2x7hPFNProstaglandin reductase 310.458
3clxX22E3 ubiquitin-protein ligase XIAP6.3.20.458
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.458
4e2yJHZMethyltransferase/0.458
4l8u9AZSerum albumin/0.458
4s1iPLPPyridoxal kinase, putative/0.458
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.457
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.457
1x8lOXRRetinol dehydratase/0.457
2cndFADNitrate reductase [NADH]1.7.1.10.457
3p0fBAUUridine phosphorylase 22.4.2.30.457
3vg10GTBeta-secretase 13.4.23.460.457
4to0DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.457
5dozNDPJamJ/0.457
1bk0ACVIsopenicillin N synthase1.21.3.10.456
1knrFADL-aspartate oxidase1.4.3.160.456
1krhFADBenzoate 1,2-dioxygenase electron transfer component1.18.1.30.456
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2cn0F25Prothrombin3.4.21.50.456
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.456
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.456
2v3oI26Prothrombin3.4.21.50.456
3af0GDPPantothenate kinase2.7.1.330.456
3udn09BBeta-secretase 13.4.23.460.456
3zkyWT4Isopenicillin N synthase1.21.3.10.456
4e2zJHZMethyltransferase/0.456
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.455
1hb3SCVIsopenicillin N synthase1.21.3.10.455
1j9zFADNADPH--cytochrome P450 reductase/0.455
1ja1FMNNADPH--cytochrome P450 reductase/0.455
1q84TZ4Acetylcholinesterase3.1.1.70.455
1uk0FRMPoly [ADP-ribose] polymerase 12.4.2.300.455
2wjoQUDBeta-secretase 13.4.23.460.455
2xufTZ4Acetylcholinesterase3.1.1.70.455
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.455
3jqrFADFerredoxin--NADP reductase, apicoplast/0.455
3wqmB29Diterpene synthase3.1.7.80.455
4araC56Acetylcholinesterase3.1.1.70.455
4bmpFMNProtein NrdI/0.455
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.455
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.454
1ygjRMCPyridoxal kinase2.7.1.350.454
2cf9348Prothrombin3.4.21.50.454
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3c49KU8Poly [ADP-ribose] polymerase 32.4.2.300.454
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.454
3pkbY16Methionine aminopeptidase 2/0.454
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.454
4b4w9L9Bifunctional protein FolD/0.454
4bprFADFerredoxin--NADP reductase1.18.1.20.454
1gjrFADFerredoxin--NADP reductase1.18.1.20.453
1qtiGNTAcetylcholinesterase3.1.1.70.453
2avxHTFRegulatory protein SdiA/0.453
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.453
2w6pOA4Biotin carboxylase6.3.4.140.453
3junAKDPhenazine biosynthesis protein A/B/0.453
3m4p4ADAsparaginyl-tRNA synthetase, putative/0.453
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.453
4b1e6T6Beta-secretase 13.4.23.460.453
4b1hAR6Poly(ADP-ribose) glycohydrolase3.2.1.1430.453
4bamMM9Prothrombin3.4.21.50.453
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.453
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.453
4du6GTPGTP cyclohydrolase 1/0.453
4jtqNAPAldo-keto reductase family 1 member C2/0.453
4mk728OGenome polyprotein2.7.7.480.453
4rvfTYDD-mycarose 3-C-methyltransferase/0.453
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.453
1bjkFADFerredoxin--NADP reductase1.18.1.20.452
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.452
2tohHBITyrosine 3-monooxygenase1.14.16.20.452
2vqbNAPPutative flavin-containing monooxygenase/0.452
3ivcFG4Pantothenate synthetase6.3.2.10.452
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.452
3mauEXTPutative sphingosine-1-phosphate lyase/0.452
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.452
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.452
4n3l2FNProthrombin3.4.21.50.452
1d9i00PProthrombin3.4.21.50.451
1hb1OCVIsopenicillin N synthase1.21.3.10.451
1x1aSAMC-20 methyltransferase/0.451
1ypeUIPProthrombin3.4.21.50.451
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.451
2v34CTN4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.451
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.451
3sf6FDAGlutaryl-CoA dehydrogenase/0.451
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.451
3vf60H6Glucokinase2.7.1.20.451
3zoiM2WIsopenicillin N synthase1.21.3.10.451
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.451
4frkDWDBeta-secretase 13.4.23.460.451
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4j0v1H7Beta-secretase 13.4.23.460.451
4p9dTMPDeoxycytidylate deaminase/0.451
4rvdSAMD-mycarose 3-C-methyltransferase/0.451
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.451
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.450
1mvtDTMDihydrofolate reductase1.5.1.30.450
1w6rGNTAcetylcholinesterase3.1.1.70.450
1z71L17Prothrombin3.4.21.50.450
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.450
2gmsP0PPutative pyridoxamine 5-phosphate-dependent dehydrase/0.450
2gywOBIAcetylcholinesterase3.1.1.70.450
2iviACWIsopenicillin N synthase1.21.3.10.450
2jgsBTNAvidin/0.450
2xluNA7Putative flavin-containing monooxygenase/0.450
2xysSY9Soluble acetylcholine receptor/0.450
3f03FMNPentaerythritol tetranitrate reductase/0.450
3junAJDPhenazine biosynthesis protein A/B/0.450
3ske054Genome polyprotein2.7.7.480.450
3v0p4GWHisto-blood group ABO system transferase/0.450
3w6hAZMCarbonic anhydrase 14.2.1.10.450
4bupSAMHistone-lysine N-methyltransferase KMT5B2.1.1.430.450
4jln18VDeoxycytidine kinase2.7.1.740.450
4qaiFMNNADPH dehydrogenase/0.450
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.450
4xguADPPutative pachytene checkpoint protein 2/0.450
1cf3FADGlucose oxidase1.1.3.40.449
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.449
1rkwPNTHTH-type transcriptional regulator QacR/0.449
1zgbA1EAcetylcholinesterase3.1.1.70.449
2wd8VGFPteridine reductase/0.449
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.449
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.449
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.449
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.449
4bfwZVWPantothenate kinase2.7.1.330.449
4ey6GNTAcetylcholinesterase3.1.1.70.449
4k37SAMAnaerobic sulfatase-maturating enzyme1.8.980.449
1c7oPPGHemolysin/0.448
1e66HUXAcetylcholinesterase3.1.1.70.448
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.448
1g6oADPCag alpha/0.448
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1vbiNADMalate/L-lactate dehydrogenase family protein/0.448
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.448
1ygkRRCPyridoxal kinase2.7.1.350.448
1zgi382Prothrombin3.4.21.50.448
2cdaNAPGlucose 1-dehydrogenase/0.448
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.448
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.448
2xuoTZ4Acetylcholinesterase3.1.1.70.448
2zfq45UProthrombin3.4.21.50.448
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.448
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
3k8q22APurine nucleoside phosphorylase2.4.2.10.448
3ufl508Beta-secretase 13.4.23.460.448
3w5uFADFerredoxin/0.448
4bahMELProthrombin3.4.21.50.448
4bb3KKAIsopenicillin N synthase1.21.3.10.448
4nv0MG77-methylguanosine phosphate-specific 5'-nucleotidase/0.448
5dp2NAPCurF/0.448
1zgv501Prothrombin3.4.21.50.447
2gmuPDGPutative pyridoxamine 5-phosphate-dependent dehydrase/0.447
2ok8FADFerredoxin--NADP reductase, apicoplast/0.447
2qe2452Polyprotein/0.447
2x96RX3Angiotensin-converting enzyme3.4.15.10.447
3arpDEQChitinase A/0.447
3qtv06PProthrombin3.4.21.50.447
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.447
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.447
4mk828QGenome polyprotein2.7.7.480.447
4nv10FXFormyl transferase/0.447
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.446
1fmjRTLRetinol dehydratase/0.446
1fueFMNFlavodoxin/0.446
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.446
1nhkCMPNucleoside diphosphate kinase2.7.4.60.446
1v5z2HCMajor NAD(P)H-flavin oxidoreductase1.6.990.446
1w87FADFerredoxin--NADP reductase1.18.1.20.446
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2b5oFADFerredoxin--NADP reductase1.18.1.20.446
2bu9HFVIsopenicillin N synthase1.21.3.10.446
2futH1SHeparin and heparin-sulfate lyase/0.446
2gl0ADNUncharacterized protein/0.446
2jh5895Prothrombin3.4.21.50.446
2r8pT6FTransketolase 1/0.446
2xuhTZ4Acetylcholinesterase3.1.1.70.446
2y60M8FIsopenicillin N synthase1.21.3.10.446
2zfr46UProthrombin3.4.21.50.446
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.446
3af1GDPPantothenate kinase2.7.1.330.446
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.446
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.446
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.446
4jjkFOLFormate--tetrahydrofolate ligase/0.446
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.445
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.445
1odcA8BAcetylcholinesterase3.1.1.70.445
1r5gAO1Methionine aminopeptidase 2/0.445
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.445
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.445
2w0wLZSBifunctional protein GlmU/0.445
2y6fM9FIsopenicillin N synthase1.21.3.10.445
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.445
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.445
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.445
3gn73GNPoly [ADP-ribose] polymerase 12.4.2.300.445
3in6FMNUncharacterized protein/0.445
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.445
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.445
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.445
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4r5wXAVPoly [ADP-ribose] polymerase 12.4.2.300.445
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.445
4z4pSAHHistone-lysine N-methyltransferase 2D2.1.1.430.445
1h63FMNPentaerythritol tetranitrate reductase/0.444
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.444
1t4u81AProthrombin3.4.21.50.444
1u65CP0Acetylcholinesterase3.1.1.70.444
1yryMSGPurine nucleoside phosphorylase2.4.2.10.444
2a9z26AAdenosine kinase2.7.1.200.444
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.444
2uuk897Prothrombin3.4.21.50.444
2vkeTACTetracycline repressor protein class D/0.444
2wwjY28Lysine-specific demethylase 4A/0.444
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.444
2zs9ADPPantothenate kinase2.7.1.330.444
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.444
3h3t16HCollagen type IV alpha-3-binding protein/0.444
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.444
3vilSA0Beta-glucosidase/0.444
4bftZVTPantothenate kinase2.7.1.330.444
4bfvZVVPantothenate kinase2.7.1.330.444
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.444
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.444
4h6pFMNChromate reductase/0.444
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
1fdrFADFerredoxin--NADP reductase1.18.1.20.443
1lnmDTXBilin-binding protein/0.443
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.443
1votHUPAcetylcholinesterase3.1.1.70.443
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.443
2fs4PZ1Renin3.4.23.150.443
2gyuHI6Acetylcholinesterase3.1.1.70.443
2hdjNDPAldo-keto reductase family 1 member C2/0.443
2j3qTFLAcetylcholinesterase3.1.1.70.443
2wu4HBPAcetylcholinesterase3.1.1.70.443
2xlpFADPutative flavin-containing monooxygenase/0.443
3cow52HPantothenate synthetase6.3.2.10.443
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.443
3mauPLRPutative sphingosine-1-phosphate lyase/0.443
3ojxFADNADPH--cytochrome P450 reductase/0.443
3to3ATPPetrobactin biosynthesis protein AsbB/0.443
4arbC57Acetylcholinesterase3.1.1.70.443
4kbyC2EStimulator of interferon genes protein/0.443
4l7h1W1Beta-secretase 13.4.23.460.443
4oztP1AEcdysone receptor, putative/0.443
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.443
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.443
5f54TMPSingle-stranded-DNA-specific exonuclease/0.443
5stdUNNScytalone dehydratase4.2.1.940.443
1fmlRTLRetinol dehydratase/0.442
1h50FMNPentaerythritol tetranitrate reductase/0.442
1mueCDDProthrombin3.4.21.50.442
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.442
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.442
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.442
1t7o152Carnitine O-acetyltransferase2.3.1.70.442
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
1v453DGPurine nucleoside phosphorylase2.4.2.10.442
1yplRA8Prothrombin3.4.21.50.442
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.442
2e1mFADL-glutamate oxidase/0.442
2ea2F77Methionine aminopeptidase 2/0.442
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.442
2ohiFMNType A flavoprotein FprA10.442
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.442
2r6hFADNa(+)-translocating NADH-quinone reductase subunit F/0.442
2vcmM11Isopenicillin N synthase1.21.3.10.442
2xugTZ4Acetylcholinesterase3.1.1.70.442
2xupTZ5Acetylcholinesterase3.1.1.70.442
2zcjSAHModification methylase HhaI2.1.1.370.442
3klbFMNUncharacterized protein/0.442
3mhtSAHModification methylase HhaI2.1.1.370.442
3mj4URMUDP-galactopyranose mutase/0.442
3v0o4GWHisto-blood group ABO system transferase/0.442
4acxS8ZBeta-secretase 13.4.23.460.442
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.442
4b2gV1NUncharacterized protein/0.442
4cf7ADPAdenylate kinase/0.442
4gi5FADPutative NAD(P)H dehydrogenase (Quinone)/0.442
4jq3NAPAldo-keto reductase family 1 member C2/0.442
4rxqDUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.442
4v2gCTCTetracycline repressor protein class D/0.442
5f8eSAHPossible transcriptional regulatory protein/0.442
5d5aCAUBeta-2 adrenergic receptor/0.442
1blzACVIsopenicillin N synthase1.21.3.10.441
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.441
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.441
1icqOPD12-oxophytodienoate reductase 11.3.1.420.441
1ix1BB2Peptide deformylase/0.441
1krrACOGalactoside O-acetyltransferase2.3.1.180.441
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1w76GNTAcetylcholinesterase3.1.1.70.441
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.441
2cv2GSUGlutamate--tRNA ligase6.1.1.170.441
2ohjFMNType A flavoprotein FprA10.441
2v5aLZLBiotin carboxylase6.3.4.140.441
2vq7FADPutative flavin-containing monooxygenase/0.441
2xlsNAPPutative flavin-containing monooxygenase/0.441
2zevIPEGeranylgeranyl pyrophosphate synthase/0.441
2zgb21UProthrombin3.4.21.50.441
3djjFADGlutathione reductase, mitochondrial1.8.1.70.441
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.441
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3p1799PProthrombin3.4.21.50.441
3pqbVGPPutative oxidoreductase/0.441
3s8pSAMHistone-lysine N-methyltransferase KMT5B2.1.1.430.441
3udq09EBeta-secretase 13.4.23.460.441
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.441
4bfxZVXPantothenate kinase2.7.1.330.441
4bj9UHBTankyrase-22.4.2.300.441
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.441
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.441
5cmx0G6Prothrombin3.4.21.50.441
5kgpACOPredicted acetyltransferase/0.441
4u140HKMuscarinic acetylcholine receptor M3/0.441
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.440
1ex75GPGuanylate kinase2.7.4.80.440
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.440
1ut6A8NAcetylcholinesterase3.1.1.70.440
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
1x1cSAHC-20 methyltransferase/0.440
1yhjR6CPyridoxal kinase2.7.1.350.440
1zdwFLVPrenyltransferase/0.440
2cekN8TAcetylcholinesterase3.1.1.70.440
2cv1ATPGlutamate--tRNA ligase6.1.1.170.440
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
2ejzSAHDiphthine synthase/0.440
2zi224UProthrombin3.4.21.50.440
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.440
3cr0809Wee1-like protein kinase2.7.10.20.440
3dufR1TPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.440
3dufR1TPyruvate dehydrogenase E1 component subunit beta1.2.4.10.440
3fpkFADFerredoxin-NADP reductase/0.440
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.440
3h3sH15Collagen type IV alpha-3-binding protein/0.440
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3p74FMNPentaerythritol tetranitrate reductase/0.440
3pm1ETHTH-type transcriptional regulator QacR/0.440
3zkuHCVIsopenicillin N synthase1.21.3.10.440
4ax9N5NProthrombin3.4.21.50.440
4hn1TYDdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.440
4ih71ERGenome polyprotein2.7.7.480.440
4j1e1HMBeta-secretase 13.4.23.460.440
4knzCB3Thymidylate synthase/0.440
4mlp2CXCryptochrome-2/0.440
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.440
4qohSTLRibosyldihydronicotinamide dehydrogenase [quinone]/0.440
4req5ADMethylmalonyl-CoA mutase large subunit5.4.99.20.440
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.440
5ds309LPoly [ADP-ribose] polymerase 12.4.2.300.440
5f12FMNNAD(P)H dehydrogenase (quinone)/0.440