sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 1.000 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.675 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.658 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.646 | |
| 4dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.643 | |
| 1rm4 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.640 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.640 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.639 | |
| 4boy | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.639 | |
| 2dbv | NDP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.635 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.631 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.631 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.630 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.628 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.626 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.622 | |
| 1gyp | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.621 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.621 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.621 | |
| 3gnq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.618 | |
| 2d2i | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.616 | |
| 1qxs | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.615 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.611 | |
| 1rm3 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.609 | |
| 1a7k | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.607 | |
| 1jn0 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.607 | |
| 1vc2 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.607 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.607 | |
| 3ksd | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.601 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.601 | |
| 1znq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.600 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.597 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.597 | |
| 3lvf | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1 | / | 0.597 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.596 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.595 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.594 | |
| 2pkr | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.594 | |
| 1szj | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.592 | |
| 3zcx | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.585 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.584 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.577 | |
| 3l0d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.576 | |
| 2vyv | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.565 | |
| 1ywg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.553 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.551 | |
| 3k2b | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.533 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.511 | |
| 1ml3 | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.499 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.498 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.495 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.491 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.490 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.488 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.488 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.485 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.485 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.482 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.482 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.481 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.481 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.481 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.480 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.479 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.479 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.477 | |
| 2pca | SAH | Diphthine synthase | / | 0.477 | |
| 2qnq | QN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.477 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.477 | |
| 1gqt | ACP | Ribokinase | / | 0.476 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.476 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.476 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.475 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.475 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.475 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.473 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.473 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.472 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.472 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.472 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.472 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.472 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.471 | |
| 1yw1 | FMN | Putative monooxygenase MoxC | 1.14 | 0.470 | |
| 1zmc | NAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.470 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.470 | |
| 3b9l | AZZ | Serum albumin | / | 0.470 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.470 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.470 | |
| 4qec | NAP | ElxO | / | 0.470 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.470 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.469 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.469 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.469 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.468 | |
| 3h8b | NSY | Cathepsin L1 | 3.4.22.15 | 0.468 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.468 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.468 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.467 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.467 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.467 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.466 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.466 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.466 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.466 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.466 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.466 | |
| 3qn8 | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.466 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.466 | |
| 3u9e | COA | Lmo1369 protein | / | 0.466 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.466 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.465 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.465 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.465 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.465 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.464 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.464 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.464 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.464 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.463 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.463 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.463 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.463 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.463 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 4j5j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 3gob | HXX | DdmC | / | 0.462 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.462 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.462 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.462 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.461 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.461 | |
| 2r43 | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.461 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.460 | |
| 2idw | 017 | Protease | / | 0.460 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.460 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.460 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.460 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.460 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.460 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.460 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.460 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.459 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.459 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 2egb | SAH | Diphthine synthase | / | 0.459 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.459 | |
| 2p2h | 994 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.459 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.459 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.459 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 3so9 | 017 | Pol protein | / | 0.459 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.458 | |
| 2yn8 | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.458 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.458 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.458 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.458 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.458 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.458 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1fml | RTL | Retinol dehydratase | / | 0.457 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.457 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.457 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.457 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.457 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.457 | |
| 3o9c | K20 | Pol polyprotein | / | 0.457 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.457 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.457 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.457 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.457 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.456 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.456 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.456 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.456 | |
| 2i4v | DJR | V-1 protease | / | 0.456 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.456 | |
| 3ras | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.456 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.456 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.456 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.456 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.456 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.456 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.456 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1vij | BAY | Gag-Pol polyprotein | / | 0.455 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.455 | |
| 3qp0 | NI8 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3qrm | NK7 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.455 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4die | C5P | Cytidylate kinase | / | 0.455 | |
| 4ebf | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.455 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.455 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.455 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.455 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.454 | |
| 1okz | UCN | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.454 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.454 | |
| 1sh9 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.454 | |
| 2nnp | ROC | Protease | / | 0.454 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.454 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.454 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.454 | |
| 3kfs | 3TL | Gag-Pol polyprotein | / | 0.454 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.454 | |
| 4wkq | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.454 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.453 | |
| 1fg6 | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.453 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2ejz | SAH | Diphthine synthase | / | 0.453 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.453 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.453 | |
| 2r3t | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2uy0 | HV1 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.453 | |
| 3ac3 | KSH | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.453 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.453 | |
| 3qpj | N4I | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3t11 | 3T1 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.453 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.453 | |
| 4njs | G08 | Protease | / | 0.453 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.453 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.452 | |
| 1llq | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.452 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.452 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.452 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.452 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.452 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.452 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.452 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.452 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.452 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.452 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.452 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.451 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.451 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.451 | |
| 2c5n | CK8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 2fxd | DR7 | Pol polyprotein | / | 0.451 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.451 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.451 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3s8c | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.451 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.451 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.451 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.451 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.451 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4fmq | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4fv9 | E71 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.451 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.451 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.451 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.451 | |
| 1c70 | L75 | Protease | / | 0.450 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.450 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.450 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.450 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.450 | |
| 2a4f | AAU | V-1 protease | / | 0.450 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2q63 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.450 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.450 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.450 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.450 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.450 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.450 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.450 | |
| 3w16 | P9J | Aurora kinase A | 2.7.11.1 | 0.450 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.450 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1ida | 0PO | Gag-Pol polyprotein | 3.4.23.47 | 0.449 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.449 | |
| 1mbt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.449 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.449 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.449 | |
| 2qd8 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.449 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.449 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.449 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.449 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.449 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.449 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.449 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4hxy | NDP | Plm1 | / | 0.449 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.449 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.448 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.448 | |
| 2r5q | 1UN | Gag-Pol polyprotein | / | 0.448 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.448 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.448 | |
| 3d1z | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.448 | |
| 3gi4 | K60 | Gag-Pol polyprotein | / | 0.448 | |
| 3o9d | K19 | Pol polyprotein | / | 0.448 | |
| 3o9h | K2E | Gag-Pol polyprotein | / | 0.448 | |
| 3qrs | NK8 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.448 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.448 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.448 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4fux | E75 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.448 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.448 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1hvi | A77 | Protease | / | 0.447 | |
| 2aa0 | MTP | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.447 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2q29 | ACO | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.447 | |
| 2q5k | AB1 | Protease | / | 0.447 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.447 | |
| 2zm1 | KSF | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.447 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.447 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3nbv | ANP | Ketohexokinase | / | 0.447 | |
| 3u8w | 09J | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4b99 | R4L | Mitogen-activated protein kinase 7 | 2.7.11.24 | 0.447 | |
| 4eut | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.447 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.447 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.447 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.446 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.446 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.446 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.446 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.446 | |
| 2q55 | MU0 | Protease | / | 0.446 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.446 | |
| 2zpa | ADP | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.446 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3ggu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.446 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.446 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3kf0 | 3TL | Gag-Pol polyprotein | / | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3nu4 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.446 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.446 | |
| 4cdm | FAD | Deoxyribodipyrimidine photolyase | / | 0.446 | |
| 4djr | 0KJ | Pol polyprotein | / | 0.446 | |
| 4dqh | 017 | Gag-Pol polyprotein | / | 0.446 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.446 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.445 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1hvs | A77 | Gag-Pol polyprotein | / | 0.445 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.445 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 2el0 | SAH | Diphthine synthase | / | 0.445 | |
| 2f80 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.445 | |
| 2hs2 | 017 | Protease | / | 0.445 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.445 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2wpx | ACO | Orf14 | / | 0.445 | |
| 3bxs | DRS | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3gga | GGW | Gag-Pol polyprotein | / | 0.445 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.445 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.445 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.445 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.445 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.444 | |
| 1eby | BEB | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1idb | 0DO | Gag-Pol polyprotein | / | 0.444 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.444 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.444 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.444 | |
| 2avv | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.444 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2fie | A74 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.444 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 2z4o | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.444 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
| 3cis | ATP | Universal stress protein Rv2623 | / | 0.444 | |
| 3d1x | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.444 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.444 | |
| 3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 3oxc | ROC | Protease | / | 0.444 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.444 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4c62 | XWW | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 4dja | FAD | (6-4) photolyase | / | 0.444 | |
| 4fv0 | EK3 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.444 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 4i23 | 1C9 | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4j1r | I5R | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.444 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.444 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.444 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.444 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1bv7 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.443 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.443 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2el3 | SAH | Diphthine synthase | / | 0.443 | |
| 2fdd | 385 | Pol protein | / | 0.443 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.443 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.443 | |
| 2r38 | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3cgd | NAD | Coenzyme A disulfide reductase | / | 0.443 | |
| 3co9 | 3MS | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.443 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3k9v | CPS | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | / | 0.443 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3qro | NK9 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.443 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.443 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 3wbl | PDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.443 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.443 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.443 | |
| 4q1x | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.443 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.443 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.443 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.442 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.442 | |
| 1z1h | HBB | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cvu | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.442 | |
| 2dcn | ADP | 2-keto-3-deoxy-gluconate kinase | / | 0.442 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.442 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.442 | |
| 2i4u | DJR | Protease | / | 0.442 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.442 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.442 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3gco | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.442 | |
| 3kdd | JZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3kfn | 3TL | Gag-Pol polyprotein | / | 0.442 | |
| 3lit | E15 | Protease | / | 0.442 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3qih | NI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3sa6 | F71 | Protease | / | 0.442 | |
| 3ts1 | TYA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.442 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.442 | |
| 4dqb | 017 | Gag-Pol polyprotein | / | 0.442 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.442 | |
| 4q1w | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.442 | |
| 1hxb | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.441 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1mui | AB1 | Protease | / | 0.441 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2bxm | IMN | Serum albumin | / | 0.441 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.441 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2gs7 | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2ieo | 017 | Protease | / | 0.441 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.441 | |
| 2pwr | G4G | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2rkf | AB1 | Pol protein | / | 0.441 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 2yww | ATP | Aspartate carbamoyltransferase regulatory chain | / | 0.441 | |
| 3cyx | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.441 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.441 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3o9i | A61 | Gag-Pol polyprotein | / | 0.441 | |
| 3ucb | 017 | Gag-Pol polyprotein | / | 0.441 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.441 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.441 | |
| 4mk7 | 28O | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 4qed | NAP | ElxO | / | 0.441 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.441 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.441 | |
| 5a3c | NAD | SIR2 family protein | / | 0.441 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.441 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.440 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.440 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.440 | |
| 2f3k | RO1 | Protease | / | 0.440 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.440 | |
| 2qd7 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2qhz | MZ2 | Gag-Pol polyprotein | / | 0.440 | |
| 2vg7 | NNI | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2y3s | TIR | TamL | / | 0.440 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.440 | |
| 3lzv | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 3o0o | GDP | Vitamin B12-dependent ribonucleotide reductase | / | 0.440 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.440 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.440 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.440 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.440 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.440 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.440 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4j49 | NAI | Uncharacterized protein | / | 0.440 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.440 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.440 | |
| 4u7w | NDP | MxaA | / | 0.440 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.440 |