sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4cj3 | E4F | Integrase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4cj3 | E4F | Integrase | / | 1.000 | |
| 4cje | Q31 | Integrase | / | 0.721 | |
| 4cer | VL4 | Integrase | / | 0.702 | |
| 4cfa | WOP | Integrase | / | 0.671 | |
| 4cjq | VXO | Integrase | / | 0.642 | |
| 4ceo | G0T | Integrase | / | 0.629 | |
| 4cjk | H39 | Integrase | / | 0.624 | |
| 4cj5 | 4VW | Integrase | / | 0.623 | |
| 4cig | X0P | Integrase | / | 0.617 | |
| 4ces | NFW | Integrase | / | 0.614 | |
| 3zsr | O3N | Integrase | / | 0.612 | |
| 4cez | O3N | Integrase | / | 0.612 | |
| 4cfb | OM3 | Integrase | / | 0.612 | |
| 4cgj | NZL | Integrase | / | 0.611 | |
| 4ced | 9NS | Integrase | / | 0.610 | |
| 4ce9 | O3N | Integrase | / | 0.606 | |
| 4cf0 | O5U | Integrase | / | 0.602 | |
| 4cgh | LOZ | Integrase | / | 0.601 | |
| 4cf8 | V7H | Integrase | / | 0.597 | |
| 4cgg | K5Q | Integrase | / | 0.591 | |
| 3zsw | ZSW | Integrase | / | 0.590 | |
| 4ceq | QCH | Integrase | / | 0.590 | |
| 4ck3 | K1T | Integrase | / | 0.588 | |
| 4cgd | 8P3 | Integrase | / | 0.586 | |
| 4cef | D0T | Integrase | / | 0.584 | |
| 4ck2 | NVU | Integrase | / | 0.584 | |
| 4cea | ZSW | Integrase | / | 0.583 | |
| 4cf1 | IY7 | Integrase | / | 0.582 | |
| 4cjf | RVN | Integrase | / | 0.582 | |
| 3zsq | O4N | Integrase | / | 0.581 | |
| 4chy | C5Q | Integrase | / | 0.581 | |
| 4cjr | FYM | Integrase | / | 0.581 | |
| 4cif | JDX | Integrase | / | 0.576 | |
| 3zt0 | ZT0 | Integrase | / | 0.568 | |
| 4cju | JNS | Integrase | / | 0.566 | |
| 4cec | 2SS | Integrase | / | 0.557 | |
| 4ck1 | OM1 | Integrase | / | 0.557 | |
| 3zsy | OM3 | Integrase | / | 0.554 | |
| 3zt3 | ZT4 | Integrase | / | 0.554 | |
| 4cf2 | 3GM | Integrase | / | 0.554 | |
| 4cfd | S8Y | Integrase | / | 0.553 | |
| 4cie | Y7N | Integrase | / | 0.553 | |
| 3zsz | OM2 | Integrase | / | 0.549 | |
| 4cgi | NZL | Integrase | / | 0.549 | |
| 4cjp | 4D2 | Integrase | / | 0.549 | |
| 4cfc | 7NV | Integrase | / | 0.546 | |
| 4cee | B0T | Integrase | / | 0.544 | |
| 4chq | CWU | Integrase | / | 0.543 | |
| 4cjs | L0Y | Integrase | / | 0.540 | |
| 3zt2 | ZT2 | Integrase | / | 0.535 | |
| 4cj4 | S3G | Integrase | / | 0.531 | |
| 3zcm | PX3 | Integrase | / | 0.530 | |
| 3zt1 | OM1 | Integrase | / | 0.530 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 3zsv | ZSV | Integrase | / | 0.519 | |
| 4ceb | ZSV | Integrase | / | 0.519 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.504 | |
| 3zsx | N44 | Integrase | / | 0.500 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.497 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 2vyv | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.491 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.491 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.491 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.486 | |
| 3cif | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.486 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.485 | |
| 3cps | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.484 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.484 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.484 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.482 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.481 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.480 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.480 | |
| 1nqo | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.479 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.478 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.478 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.477 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.477 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.476 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.475 | |
| 5da9 | AGS | Uncharacterized protein | / | 0.475 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.475 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.474 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.474 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.474 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.474 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.473 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.473 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.472 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.472 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.472 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.472 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.472 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 2y3s | TIR | TamL | / | 0.470 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.470 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.469 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.469 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.469 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.469 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.468 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.467 | |
| 2xrw | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.467 | |
| 2xs0 | ANP | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.467 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.467 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.467 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.467 | |
| 1nqa | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.466 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.466 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.466 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.466 | |
| 1ii6 | ADP | Kinesin-like protein KIF11 | / | 0.465 | |
| 2d3m | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.465 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.465 | |
| 3iph | G11 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.465 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.464 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.464 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.464 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.464 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.464 | |
| 5il1 | SAM | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.464 | |
| 2dxv | SAH | Diphthine synthase | / | 0.463 | |
| 3gob | HXX | DdmC | / | 0.463 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.463 | |
| 3r4b | 74T | Gag-Pol polyprotein | / | 0.463 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.463 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.463 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.463 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.462 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.462 | |
| 2xnb | Y8L | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.462 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.462 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.462 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.462 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.461 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.461 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.461 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.460 | |
| 2cke | IQU | Death-associated protein kinase 2 | / | 0.460 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.460 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.460 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.460 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.460 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.460 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.460 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.460 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.460 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.460 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.459 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.459 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.459 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.459 | |
| 4kip | 1R9 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.458 | |
| 2dsh | SAH | Diphthine synthase | / | 0.458 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.458 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.458 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 4bdf | H3R | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.458 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.458 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.458 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.457 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.457 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.457 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.457 | |
| 3q5d | GDP | Atlastin-1 | 3.6.5 | 0.457 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.457 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1dcy | I3N | Phospholipase A2, membrane associated | / | 0.456 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.456 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.456 | |
| 2egb | SAH | Diphthine synthase | / | 0.456 | |
| 2p5f | SAH | Diphthine synthase | / | 0.456 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.456 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.456 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.456 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.456 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.456 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2p6l | SAH | Diphthine synthase | / | 0.455 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.455 | |
| 3eks | CY9 | Actin-5C | / | 0.455 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.455 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.455 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.455 | |
| 4xq9 | NAD | Homospermidine synthase | 2.5.1.44 | 0.455 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.454 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.454 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.454 | |
| 3kvx | FMY | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.454 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.454 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.454 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.454 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.454 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.453 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.453 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.453 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2vtn | LZ7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.453 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.453 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.453 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.453 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.453 | |
| 1cer | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.452 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.452 | |
| 3sw4 | 18K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.452 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.452 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.452 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.452 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.451 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.451 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2j0l | ANP | Focal adhesion kinase 1 | 2.7.10.2 | 0.451 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.451 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.451 | |
| 3b9l | AZZ | Serum albumin | / | 0.451 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.451 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.451 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.451 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 4a9r | RU5 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.451 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.451 | |
| 4hxy | NDP | Plm1 | / | 0.451 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.451 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2e08 | SAH | Diphthine synthase | / | 0.450 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.450 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.450 | |
| 2h12 | CMX | Citrate synthase | / | 0.450 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.450 | |
| 3lki | ATP | Fructokinase | / | 0.450 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.450 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.450 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.450 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.450 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1c6y | MK1 | Protease | / | 0.449 | |
| 1u30 | GOX | Pancreatic alpha-amylase | / | 0.449 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.449 | |
| 2e07 | SAH | Diphthine synthase | / | 0.449 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.449 | |
| 2yyu | C5P | Orotidine 5'-phosphate decarboxylase | / | 0.449 | |
| 3a6r | FMN | FMN-binding protein | / | 0.449 | |
| 4bdb | ODO | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.449 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.449 | |
| 4l4x | NDP | AmphI | / | 0.449 | |
| 4otw | DB8 | Receptor tyrosine-protein kinase erbB-3 | 2.7.10.1 | 0.449 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.449 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.449 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.448 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.448 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.448 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.448 | |
| 3a7h | ATP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.448 | |
| 3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3r8z | Z63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.448 | |
| 4hj6 | FMN | LOV protein | / | 0.448 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.448 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.448 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.448 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.448 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.447 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 1tcx | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.447 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.447 | |
| 2ijg | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.447 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.447 | |
| 2r9e | SDX | Citrate synthase | 2.3.3.16 | 0.447 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.447 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.447 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.447 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.447 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.447 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.447 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.447 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.447 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.447 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.446 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.446 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.446 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.446 | |
| 2bx8 | AZQ | Serum albumin | / | 0.446 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.446 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.446 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.446 | |
| 2owk | SAH | Diphthine synthase | / | 0.446 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.446 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.446 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.446 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.446 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.446 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.446 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.446 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.446 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.446 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.446 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.446 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.446 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4l8u | 9AZ | Serum albumin | / | 0.446 | |
| 4mgi | CMP | Rap guanine nucleotide exchange factor 4 | / | 0.446 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.446 | |
| 1a8g | 2Z4 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.445 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1gih | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1osv | CHC | Bile acid receptor | / | 0.445 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.445 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.445 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.445 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.445 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2huq | SAH | Diphthine synthase | / | 0.445 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 3flz | FLZ | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.445 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3lct | ADP | ALK tyrosine kinase receptor | 2.7.10.1 | 0.445 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 3uqd | ADP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.445 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.445 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.445 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.445 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.445 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.444 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.444 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.444 | |
| 1wng | SAH | Diphthine synthase | / | 0.444 | |
| 1yre | COA | Uncharacterized protein | / | 0.444 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.444 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.444 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.444 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2ycr | HCW | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.444 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.444 | |
| 3gry | SAM | Probable ribosomal RNA small subunit methyltransferase A | / | 0.444 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.444 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 3qpj | N4I | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 4ajo | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4e8w | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.444 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.444 | |
| 4ew2 | DXY | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.444 | |
| 4f65 | 0S9 | Fibroblast growth factor receptor 1 | / | 0.444 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.444 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.444 | |
| 4zoh | FAD | Putative oxidoreductase FAD-binding subunit | / | 0.444 | |
| 5dp2 | NAP | CurF | / | 0.444 | |
| 1dm2 | HMD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.443 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.443 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.443 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.443 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 1znq | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.443 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.443 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2dsg | SAH | Diphthine synthase | / | 0.443 | |
| 2e4n | SAH | Diphthine synthase | / | 0.443 | |
| 2ele | SAH | Diphthine synthase | / | 0.443 | |
| 2fyp | RDE | Endoplasmin | / | 0.443 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.443 | |
| 2hut | SAH | Diphthine synthase | / | 0.443 | |
| 2huv | SAH | Diphthine synthase | / | 0.443 | |
| 2owu | SAH | Diphthine synthase | / | 0.443 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.443 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.443 | |
| 3s56 | ROC | Protease | / | 0.443 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4f4q | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.443 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 4jl6 | ADP | Adenylate kinase | / | 0.443 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.443 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 5d4v | SAH | Uncharacterized protein MJ0489 | / | 0.443 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.442 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.442 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.442 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 1q3e | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.442 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.442 | |
| 1vce | SAH | Diphthine synthase | / | 0.442 | |
| 1x14 | NAD | NAD(P) transhydrogenase subunit alpha | 1.6.1.2 | 0.442 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.442 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2dek | SAH | Diphthine synthase | / | 0.442 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.442 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.442 | |
| 2p3b | 3TL | V-1 protease | / | 0.442 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.442 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.442 | |
| 3e8x | NAP | BH1520 protein | / | 0.442 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3k2b | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.442 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.442 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.442 | |
| 3ork | AGS | Serine/threonine protein kinase | / | 0.442 | |
| 3ts4 | EEG | Macrophage metalloelastase | 3.4.24.65 | 0.442 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.442 | |
| 4e6d | 0NU | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4f9c | 0SX | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.442 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4ie6 | UN9 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.442 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.442 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 4jld | ADP | Adenylate kinase | / | 0.442 | |
| 4jlo | ADP | Adenylate kinase | / | 0.442 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.442 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.441 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.441 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.441 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.441 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.441 | |
| 2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.441 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.441 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.441 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.441 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.441 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.441 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 3w77 | FMN | FMN-dependent NADH-azoreductase | / | 0.441 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.441 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.441 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4oae | CLM | Uncharacterized protein | / | 0.441 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.441 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.441 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.440 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.440 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.440 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.440 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.440 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.440 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.440 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.440 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.440 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.440 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.440 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.440 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.440 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.440 | |
| 3mje | NDP | AmphB | / | 0.440 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3qzf | X66 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.440 | |
| 3v0t | ATR | Perakine reductase | 1.1.1.317 | 0.440 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.440 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.440 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.440 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 4e2d | FMN | Dehydrogenase | / | 0.440 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.440 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.440 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.440 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.440 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.440 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.440 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.440 |