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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4joa3DKALK tyrosine kinase receptor2.7.10.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4joa3DKALK tyrosine kinase receptor2.7.10.11.000
3w2o03PEpidermal growth factor receptor2.7.10.10.564
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.535
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.528
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.528
2xp2VGHALK tyrosine kinase receptor2.7.10.10.523
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.523
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.523
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.519
2yfxVGHALK tyrosine kinase receptor2.7.10.10.515
4anqVGHALK tyrosine kinase receptor2.7.10.10.515
2itwITQEpidermal growth factor receptor2.7.10.10.514
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.514
3vjoANPEpidermal growth factor receptor2.7.10.10.513
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.511
5aacVGHALK tyrosine kinase receptor2.7.10.10.511
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.508
4ansVGHALK tyrosine kinase receptor2.7.10.10.508
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.508
4c3pACPAurora kinase A2.7.11.10.507
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.507
3cokANPSerine/threonine-protein kinase PLK42.7.11.210.506
4i231C9Epidermal growth factor receptor2.7.10.10.506
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.503
2of2547Tyrosine-protein kinase Lck2.7.10.20.499
4i22IREEpidermal growth factor receptor2.7.10.10.499
1m17AQ4Epidermal growth factor receptor2.7.10.10.498
4id71G0Activated CDC42 kinase 1/0.498
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.496
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.495
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.494
4gk4L90Ephrin type-A receptor 32.7.10.10.494
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.493
2vrx447Aurora kinase B-A2.7.11.10.492
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.492
2ittAEEEpidermal growth factor receptor2.7.10.10.491
4gt3ATPMitogen-activated protein kinase 12.7.11.240.491
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.490
3d7tSTUTyrosine-protein kinase CSK/0.490
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.490
4fob0USALK tyrosine kinase receptor2.7.10.10.490
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.489
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.489
4nks2M2Fibroblast growth factor receptor 1/0.489
1pjkANPCasein kinase II subunit alpha2.7.11.10.488
2itnANPEpidermal growth factor receptor2.7.10.10.488
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.488
4jboWPHAurora kinase A2.7.11.10.488
4qo9627Serine/threonine-protein kinase 242.7.11.10.488
4b8mVX6Aurora kinase B-A2.7.11.10.487
4fz60VGTyrosine-protein kinase SYK2.7.10.20.487
4jq8KJ8Epidermal growth factor receptor2.7.10.10.487
2j7t274Serine/threonine-protein kinase 102.7.11.10.486
3c4xATPRhodopsin kinase/0.486
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.486
1mqbANPEphrin type-A receptor 22.7.10.10.485
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.484
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.483
2of4979Tyrosine-protein kinase Lck2.7.10.20.483
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.483
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.483
4fuxE75Mitogen-activated protein kinase 12.7.11.240.483
5aabVGHALK tyrosine kinase receptor2.7.10.10.483
3c4wATPRhodopsin kinase/0.482
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.482
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.481
4qms1N1Serine/threonine-protein kinase 242.7.11.10.481
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.481
2itpAEEEpidermal growth factor receptor2.7.10.10.480
2ituITQEpidermal growth factor receptor2.7.10.10.480
2itzIREEpidermal growth factor receptor2.7.10.10.480
2qoqANPEphrin type-A receptor 32.7.10.10.480
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.480
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.480
5aaaVGHALK tyrosine kinase receptor2.7.10.10.480
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.479
2hk51BMTyrosine-protein kinase HCK2.7.10.20.479
2qo9ANPEphrin type-A receptor 32.7.10.10.479
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.479
3vjnANPEpidermal growth factor receptor2.7.10.10.479
4fnzNZFALK tyrosine kinase receptor2.7.10.10.479
4fyn0VETyrosine-protein kinase SYK2.7.10.20.479
2c6eHPMAurora kinase A2.7.11.10.478
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.478
3vs3VSETyrosine-protein kinase HCK2.7.10.20.478
4ccbOFGALK tyrosine kinase receptor2.7.10.10.478
4jrvKJVEpidermal growth factor receptor2.7.10.10.478
4nka2K7Fibroblast growth factor receptor 1/0.478
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.478
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.477
2ijmATPFocal adhesion kinase 12.7.10.20.477
2itqITQEpidermal growth factor receptor2.7.10.10.477
1jqhANPInsulin-like growth factor 1 receptor2.7.10.10.476
2c475IDCasein kinase I isoform gamma-2/0.476
4cd0AWJALK tyrosine kinase receptor2.7.10.10.476
4kba1QMCasein kinase I isoform delta2.7.11.10.476
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.475
3qc9ADPRhodopsin kinase/0.475
4wkqIREEpidermal growth factor receptor2.7.10.10.475
1jpaANPEphrin type-B receptor 22.7.10.10.474
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
3a7hATPSerine/threonine-protein kinase 242.7.11.10.473
3q5iANPProtein kinase, putative/0.473
3uvqFS8Mitogen-activated protein kinase 14/0.473
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.473
4jr3KJREpidermal growth factor receptor2.7.10.10.473
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.473
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.472
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.472
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.472
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.472
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.472
3gubGUBDeath-associated protein kinase 12.7.11.10.472
3lctADPALK tyrosine kinase receptor2.7.10.10.472
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.472
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
2j0m4STFocal adhesion kinase 12.7.10.20.471
2ojj82AMitogen-activated protein kinase 12.7.11.240.471
2v7a627Tyrosine-protein kinase ABL12.7.10.20.471
2xvdAS6Ephrin type-B receptor 42.7.10.10.471
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.471
4enhFVXCholesterol 24-hydroxylase/0.471
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.471
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.470
3fmkFMKMitogen-activated protein kinase 14/0.470
3m8qDJZGag-Pol polyprotein2.7.7.490.470
3s4qNK0Mitogen-activated protein kinase 14/0.470
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.470
3w2sW2REpidermal growth factor receptor2.7.10.10.470
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.470
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.470
1bygSTUTyrosine-protein kinase CSK/0.469
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.469
2j0k4STFocal adhesion kinase 12.7.10.20.469
3eb0DRKUncharacterized protein/0.469
3u4uLNHCasein kinase II subunit alpha2.7.11.10.469
4aotGW8Serine/threonine-protein kinase 102.7.11.10.469
4g2fC07Ephrin type-A receptor 32.7.10.10.469
5e8xSTUTGF-beta receptor type-12.7.11.300.469
2bxe1FLSerum albumin/0.468
2eb3ANPEpidermal growth factor receptor2.7.10.10.468
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.468
3zk5Z18Cytochrome P450 monooxygenase PikC/0.468
4d58BI9Focal adhesion kinase 12.7.10.20.468
4jbqVX6Aurora kinase A2.7.11.10.468
4c62XWWTyrosine-protein kinase JAK2/0.467
4iebANPCalmodulin-domain protein kinase 1/0.467
2c7xNRBCytochrome P450 monooxygenase PikC/0.466
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.466
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.466
4c4h7RODual specificity protein kinase TTK2.7.12.10.466
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.466
4hjoAQ4Epidermal growth factor receptor2.7.10.10.466
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.466
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.465
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.465
2vx07X7Ephrin type-B receptor 42.7.10.10.465
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.465
3w33W19Epidermal growth factor receptor2.7.10.10.465
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.465
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.465
4jq7KJQEpidermal growth factor receptor2.7.10.10.465
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.465
2bfyH1NAurora kinase B-A2.7.11.10.464
2itxANPEpidermal growth factor receptor2.7.10.10.464
2uzlC94Cyclin-dependent kinase 22.7.11.220.464
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.464
4bchT7ZCyclin-dependent kinase 92.7.11.220.464
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.464
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.464
4qmlANPSerine/threonine-protein kinase 242.7.11.10.464
2jd1NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.463
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.463
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.462
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.462
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.462
3ac2KSETyrosine-protein kinase Lck2.7.10.20.462
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.462
3t8oATPRhodopsin kinase/0.462
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.462
4jbpYPHAurora kinase A2.7.11.10.462
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.462
4tuvCPZCytochrome P450 1191.140.462
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.461
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.461
2acxANPG protein-coupled receptor kinase 62.7.11.160.461
2hog710Serine/threonine-protein kinase Chk12.7.11.10.461
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.461
2xb7GUIALK tyrosine kinase receptor2.7.10.10.461
3a62STURibosomal protein S6 kinase beta-12.7.11.10.461
3bheBZNGag-Pol polyprotein3.4.23.160.461
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4f630S7Fibroblast growth factor receptor 1/0.461
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.461
4gk2L66Ephrin type-A receptor 32.7.10.10.461
4wsqKSAAP2-associated protein kinase 12.7.11.10.461
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.460
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.460
2vww7X2Ephrin type-B receptor 42.7.10.10.460
3hllI45Mitogen-activated protein kinase 14/0.460
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.460
4b99R4LMitogen-activated protein kinase 72.7.11.240.460
4ccuAWFALK tyrosine kinase receptor2.7.10.10.460
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.460
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.460
4gk3L87Ephrin type-A receptor 32.7.10.10.460
4ic7ANPMitogen-activated protein kinase 72.7.11.240.460
4o0uADNAurora kinase A2.7.11.10.460
4xhgADPUncharacterized protein/0.460
5dr9SKEAurora kinase A2.7.11.10.460
5l8lADPAurora kinase A2.7.11.10.460
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.459
2ijmADPFocal adhesion kinase 12.7.10.20.459
2vgoAD5Aurora kinase B-A2.7.11.10.459
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.459
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.459
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.459
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.458
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.458
2itvANPEpidermal growth factor receptor2.7.10.10.458
2vu3LZECyclin-dependent kinase 22.7.11.220.458
2xyuQ9GEphrin type-A receptor 42.7.10.10.458
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.458
3e5aVX6Aurora kinase A2.7.11.10.458
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.458
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.458
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.458
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
1k6tXN1Gag-Pol polyprotein3.4.23.160.457
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.457
1v0pPVBCell division control protein 2 homolog2.7.11.220.457
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.457
2etm7PYFocal adhesion kinase 12.7.10.20.457
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
3erkSB4Mitogen-activated protein kinase 12.7.11.240.457
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.456
2fgiPD1Fibroblast growth factor receptor 1/0.456
2j0j4STFocal adhesion kinase 12.7.10.20.456
2vwz7X6Ephrin type-B receptor 42.7.10.10.456
3aoxEMHALK tyrosine kinase receptor2.7.10.10.456
3gggNADPrephenate dehydrogenase/0.456
3i0rRT3Gag-Pol polyprotein2.7.7.490.456
3p3e3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.456
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.456
4dce0JFALK tyrosine kinase receptor2.7.10.10.456
4grb0XGCasein kinase II subunit alpha2.7.11.10.456
4hvg19QTyrosine-protein kinase JAK32.7.10.20.456
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.455
1xjdSTUProtein kinase C theta type2.7.11.130.455
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2c3qGTXGlutathione S-transferase theta-12.5.1.180.455
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.455
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.455
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.455
3nr4PYVAbscisic acid receptor PYL2/0.455
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.455
4bb432WEphrin type-B receptor 42.7.10.10.455
1ndeMONEstrogen receptor beta/0.454
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.454
2i0ePDSProtein kinase C beta type2.7.11.130.454
2j0lANPFocal adhesion kinase 12.7.10.20.454
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.454
2x6dX6DAurora kinase A2.7.11.10.454
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.454
3ac1KZITyrosine-protein kinase Lck2.7.10.20.454
3med65BGag-Pol polyprotein2.7.7.490.454
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.454
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.454
3t2zFADSulfide-quinone reductase/0.454
3w18N13Aurora kinase A2.7.11.10.454
4an92P7Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.454
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.454
4fnyI3KALK tyrosine kinase receptor2.7.10.10.454
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.454
4hvh19RTyrosine-protein kinase JAK32.7.10.20.454
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.454
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.454
2bx8AZQSerum albumin/0.453
2k62ITLFatty acid-binding protein, liver/0.453
2qd9LGFMitogen-activated protein kinase 14/0.453
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.453
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.453
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.453
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.453
4riyADPEpidermal growth factor receptor2.7.10.10.453
4y8wSTRSteroid 21-hydroxylase/0.453
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.453
1fm4DXCMajor pollen allergen Bet v 1-L/0.452
2izsBRQCasein kinase I isoform gamma-32.7.11.10.452
2o0uC0MMitogen-activated protein kinase 102.7.11.240.452
2p4yC03Peroxisome proliferator-activated receptor gamma/0.452
2xa4AZ5Tyrosine-protein kinase JAK2/0.452
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.452
3r9dX6BCyclin-dependent kinase 22.7.11.220.452
4c4iX20Dual specificity protein kinase TTK2.7.12.10.452
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.452
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.452
4ia3BIVVitamin D3 receptor A/0.452
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.451
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.451
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.451
2qocANPEphrin type-A receptor 32.7.10.10.451
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.451
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.451
3c50ADPRhodopsin kinase/0.451
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.451
3gu83GUDeath-associated protein kinase 12.7.11.10.451
3hx4ANPCalmodulin-domain protein kinase 1/0.451
3juhANPCasein kinase II subunit alpha2.7.11.10.451
3poz03PEpidermal growth factor receptor2.7.10.10.451
3sheI85MAP kinase-activated protein kinase 32.7.11.10.451
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.451
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.451
4gmy0X5Tyrosine-protein kinase JAK2/0.451
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.451
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
2vwu7X1Ephrin type-B receptor 42.7.10.10.450
2vzmNRBCytochrome P450 monooxygenase PikC/0.450
2z7lS91Mitogen-activated protein kinase 12.7.11.240.450
2zybKSLTyrosine-protein kinase Lck2.7.10.20.450
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
4aguD15Cyclin-dependent kinase-like 1/0.450
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.450
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.450
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.450
4f640S8Fibroblast growth factor receptor 1/0.450
1p31EPUUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.449
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.449
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.449
2q61SF1Peroxisome proliferator-activated receptor gamma/0.449
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.449
2y6o1N1Ephrin type-A receptor 42.7.10.10.449
3bu5ATPInsulin receptor2.7.10.10.449
3i60E86Mitogen-activated protein kinase 12.7.11.240.449
3kf7L9GMitogen-activated protein kinase 14/0.449
3l8p0CEAngiopoietin-1 receptor2.7.10.10.449
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.449
3opdHIEHeat shock protein 83/0.449
3uyt0CKCasein kinase I isoform delta2.7.11.10.449
3v9v21LPeroxisome proliferator-activated receptor gamma/0.449
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.449
3zsi52PMitogen-activated protein kinase 14/0.449
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.449
4g170VNCasein kinase I isoform gamma-32.7.11.10.449
4o0wADNAurora kinase A2.7.11.10.449
1k6cMK1Gag-Pol polyprotein3.4.23.160.448
1wvySTUDeath-associated protein kinase 12.7.11.10.448
1yvj4STTyrosine-protein kinase JAK32.7.10.20.448
1zys199Serine/threonine-protein kinase Chk12.7.11.10.448
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.448
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.448
2vwy7X5Ephrin type-B receptor 42.7.10.10.448
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.448
2xikJ60Serine/threonine-protein kinase 252.7.11.10.448
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.448
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
3mec65BGag-Pol polyprotein2.7.7.490.448
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.448
3zh8C58Protein kinase C iota type2.7.11.130.448
3zuxTCHTransporter/0.448
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.448
4axdANPInositol-pentakisphosphate 2-kinase2.7.1.1580.448
4eqcXR1Serine/threonine-protein kinase PAK 12.7.11.10.448
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.448
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.448
4h3qANPMitogen-activated protein kinase 12.7.11.240.448
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.448
4kb81QNCasein kinase I isoform delta2.7.11.10.448
4n6bCOAUncharacterized protein/0.448
4q5hANPProtein kinase OspG2.70.448
4qnaX11Serine/threonine-protein kinase 242.7.11.10.448
5av3KMPDeath-associated protein kinase 12.7.11.10.448
1aq1STUCyclin-dependent kinase 22.7.11.220.447
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.447
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.447
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.447
2hw1ANPKetohexokinase/0.447
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.447
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.447
2vwx7X4Ephrin type-B receptor 42.7.10.10.447
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.447
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.447
3almFAD2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase/0.447
3dt1P40Mitogen-activated protein kinase 14/0.447
3iw4LW4Protein kinase C alpha type2.7.11.130.447
3iw5DF3Mitogen-activated protein kinase 14/0.447
3qaiXNNKetohexokinase/0.447
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.447
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.447
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.447
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4r20AERCytochrome P450 family 17 polypeptide 2/0.447
5auwQUEDeath-associated protein kinase 12.7.11.10.447
1ysx4EBSerum albumin/0.446
2vn0TDZCytochrome P450 2C8/0.446
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.446
3gc9B45Mitogen-activated protein kinase 112.7.11.240.446
3p6oETGCamphor 5-monooxygenase1.14.15.10.446
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.446
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3tmz06XCytochrome P450 2B41.14.14.10.446
4bgg844Activin receptor type-12.7.11.300.446
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.446
4lsmNADGlyceraldehyde-3-phosphate dehydrogenase/0.446
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.446
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.446
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.445
1u54ACPActivated CDC42 kinase 1/0.445
1xkkFMMEpidermal growth factor receptor2.7.10.10.445
2henADPEphrin type-B receptor 22.7.10.10.445
2izrBRKCasein kinase I isoform gamma-32.7.11.10.445
2vd5BI8Myotonin-protein kinase2.7.11.10.445
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.445
3gc8B45Mitogen-activated protein kinase 112.7.11.240.445
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.445
3mdvCL6Cholesterol 24-hydroxylase/0.445
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.445
3p7bP7BMitogen-activated protein kinase 14/0.445
3vs1VSATyrosine-protein kinase HCK2.7.10.20.445
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.445
3w32W32Epidermal growth factor receptor2.7.10.10.445
4e4m0NHTyrosine-protein kinase JAK2/0.445
4hgs15GCasein kinase I isoform gamma-32.7.11.10.445
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.445
4z34ON7Lysophosphatidic acid receptor 1/0.445
1d7lRFLp-hydroxybenzoate hydroxylase/0.444
1h1s4SPCyclin-dependent kinase 22.7.11.220.444
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.444
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.444
2ckeIQUDeath-associated protein kinase 2/0.444
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.444
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.444
2xynVX6Abelson tyrosine-protein kinase 22.7.10.20.444
3bqr4RBDeath-associated protein kinase 3/0.444
3dxjNE6DNA-directed RNA polymerase subunit beta/0.444
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.444
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.444
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.444
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.444
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.444
4jdaA9SAbscisic acid receptor PYL3/0.444
4jia1K3Tyrosine-protein kinase JAK2/0.444
4o4fATPKinase/0.444
4o701QKBromodomain-containing protein 4/0.444
4yuqKS1Calmodulin-like domain protein kinase/0.444
5awmANPStress-activated protein kinase JNK2.7.11.240.444
5f8eSAHPossible transcriptional regulatory protein/0.444
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1ywrLI9Mitogen-activated protein kinase 14/0.443
2btsU32Cyclin-dependent kinase 22.7.11.220.443
2c6hPXICytochrome P450 monooxygenase PikC/0.443
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.443
2i40BLZCyclin-dependent kinase 22.7.11.220.443
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.443
2xba571ALK tyrosine kinase receptor2.7.10.10.443
2yn8STUEphrin type-B receptor 42.7.10.10.443
2zjwREFCasein kinase II subunit alpha2.7.11.10.443
3flzFLZMitogen-activated protein kinase 14/0.443
3irxUDRGag-Pol polyprotein2.7.7.490.443
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.443
3zewSTUEphrin type-B receptor 42.7.10.10.443
4btkDTQTau-tubulin kinase 12.7.11.10.443
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
4em9TCEPeroxisome proliferator-activated receptor gamma/0.443
4eym0RXMitogen-activated protein kinase 132.7.11.240.443
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.443
4fv9E71Mitogen-activated protein kinase 12.7.11.240.443
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.443
4hgt15GCasein kinase I isoform delta2.7.11.10.443
4s34ANPMitogen-activated protein kinase 12.7.11.240.443
5dr6SKEAurora kinase A2.7.11.10.443
1s6qTPBGag-Pol polyprotein2.7.7.490.442
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.442
2aibERGBeta-elicitin cinnamomin/0.442
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.442
2cd8PXICytochrome P450 monooxygenase PikC/0.442
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.442
2x9fX9FEphrin type-B receptor 42.7.10.10.442
2ydwWSHBromodomain-containing protein 2/0.442
2zioAYBPyrrolysine--tRNA ligase/0.442
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.442
3c4zADPRhodopsin kinase/0.442
3h9f92MDual specificity protein kinase TTK2.7.12.10.442
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.442
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.442
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.442
4c58824Cyclin-G-associated kinase2.7.11.10.442
4g1z0VPVitamin D3 receptor A/0.442
4l9i8PRRhodopsin kinase/0.442
4l9kEHFSerum albumin/0.442
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.442
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.442
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.442
4nr42LKCREB-binding protein/0.442
5jtbZMAAdenosine receptor A2a/0.442
1di8DTQCyclin-dependent kinase 22.7.11.220.441
1dkfBMSRetinoic acid receptor alpha/0.441
1jlcFTCGag-Pol polyprotein2.7.7.490.441
1ouy094Mitogen-activated protein kinase 14/0.441
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
1xl2189Gag-Pol polyprotein3.4.23.160.441
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.441
2pzpACPFibroblast growth factor receptor 2/0.441
2vv9IM9Cyclin-dependent kinase 22.7.11.220.441
2xszATPRuvB-like 23.6.4.120.441
3frqERYErythromycin resistance repressor protein/0.441
3hl7I47Mitogen-activated protein kinase 14/0.441
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.441
3miaANPCyclin-dependent kinase 92.7.11.220.441
3o8tBMUMitogen-activated protein kinase 14/0.441
3tguWF3Cytochrome b/0.441
3ttjJBIMitogen-activated protein kinase 102.7.11.240.441
3w0gW07Vitamin D3 receptor/0.441
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.441
3wd7COAAcridone synthase/0.441
3zxtACPDeath-associated protein kinase 12.7.11.10.441
4a9mP9MBromodomain-containing protein 2/0.441
4bcqTJFCyclin-dependent kinase 22.7.11.220.441
4ewqMWLMitogen-activated protein kinase 14/0.441
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.441
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.441
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.441
4looSB4Mitogen-activated protein kinase 14/0.441
5e8wSTUTGF-beta receptor type-12.7.11.300.441
3emlZMAAdenosine receptor A2a/0.441
1hpzAAPGag-Pol polyprotein2.7.7.490.440
1zmcNADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.440
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.440
2hw2RFPRifampin ADP-ribosyl transferase/0.440
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.440
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.440
2wqeADPAurora kinase A2.7.11.10.440
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.440
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.440
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.440
3axwTIDCasein kinase II subunit alpha2.7.11.10.440
3mtfA3FActivin receptor type-12.7.11.300.440
3qyw6PBMitogen-activated protein kinase 12.7.11.240.440
3uxyNADShort-chain dehydrogenase/reductase SDR/0.440
3vryB43Tyrosine-protein kinase HCK2.7.10.20.440
4bbe3O4Tyrosine-protein kinase JAK2/0.440
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.440
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
4hge15VTyrosine-protein kinase JAK2/0.440
4ix6ADPUncharacterized protein/0.440
4izy1J2Mitogen-activated protein kinase 82.7.11.240.440
4jqeANPCasein kinase II subunit alpha2.7.11.10.440
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.440
4o761M3Bromodomain-containing protein 4/0.440