sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4bb2 | STR | Corticosteroid-binding globulin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4bb2 | STR | Corticosteroid-binding globulin | / | 1.000 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.571 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.555 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.502 | |
| 1zdw | FLV | Prenyltransferase | / | 0.496 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.492 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.491 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.491 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.489 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.489 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.488 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.487 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.486 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.486 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.484 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.482 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.482 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.480 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.480 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.478 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.478 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.477 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.477 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.476 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.476 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.476 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.476 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.474 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.473 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.473 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.471 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.471 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.470 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.470 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.469 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.469 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.469 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.469 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.469 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.468 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.467 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.467 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.467 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3gsi | THG | Dimethylglycine oxidase | 1.5.3.10 | 0.467 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.466 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.466 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.465 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.465 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.464 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.464 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.464 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.463 | |
| 1qv0 | CZH | Obelin | / | 0.463 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.463 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.463 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.463 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.462 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.462 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.462 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.461 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.461 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.460 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.460 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.460 | |
| 3eku | CY9 | Actin-5C | / | 0.460 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.460 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.459 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.459 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.459 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.459 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.459 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.459 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.459 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.459 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.459 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.458 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.458 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.458 | |
| 3v2u | ATP | Protein GAL3 | / | 0.458 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.458 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.458 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.457 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.457 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.457 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.457 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.457 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.457 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.457 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.456 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.456 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.456 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.456 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.456 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.456 | |
| 3e6e | DCS | Alanine racemase | / | 0.456 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.456 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.456 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.456 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.456 | |
| 4isf | 1FX | Glucokinase | 2.7.1.2 | 0.456 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 1ez0 | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.455 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.455 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.455 | |
| 1qs2 | NAD | Vip2Ac | / | 0.455 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.455 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.455 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.455 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.455 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.455 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.455 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.454 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1jf0 | CZH | Obelin | / | 0.454 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.454 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.454 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.453 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.453 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.453 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.453 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.453 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.453 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.452 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.452 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.452 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.452 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.452 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.452 | |
| 4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.452 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.451 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.451 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.451 | |
| 4qij | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.451 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 4ami | G90 | Beta-1 adrenergic receptor | / | 0.451 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.450 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.450 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.450 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.450 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.450 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.450 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.450 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.450 | |
| 4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.450 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.450 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.449 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.449 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 2ejz | SAH | Diphthine synthase | / | 0.449 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.449 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.449 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.449 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.449 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.449 | |
| 4iae | 1DX | Alr2278 protein | / | 0.449 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.449 | |
| 4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.449 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.448 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.448 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 3gc5 | 2MQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.448 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.448 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.448 | |
| 3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.448 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.448 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.447 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.447 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.447 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 4amj | CVD | Beta-1 adrenergic receptor | / | 0.447 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.447 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.447 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 4nqg | CZH | Mitrocomin | / | 0.447 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.446 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.446 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.446 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2c9b | PUG | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.446 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.446 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3arp | DEQ | Chitinase A | / | 0.446 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.446 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.446 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.446 | |
| 3zia | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 3zm6 | 2GN | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.446 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.446 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.445 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.445 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.445 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.445 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.445 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.445 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.445 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.445 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 4kxj | P34 | Nucleoprotein | / | 0.445 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.445 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.444 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.444 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.444 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.444 | |
| 3pz3 | PZ3 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4o7u | THF | Thymidylate synthase | / | 0.444 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.443 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.443 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.443 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.443 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.443 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.443 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.443 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1c7o | PPG | Hemolysin | / | 0.442 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.442 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.442 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.442 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.442 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.442 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 3arv | SAU | Chitinase A | / | 0.442 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3gb4 | D3M | DdmC | / | 0.442 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3pn1 | IVH | DNA ligase | / | 0.442 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.442 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.442 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.442 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.441 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.441 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.441 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 1nw4 | IMH | Purine nucleoside phosphorylase | / | 0.441 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.441 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.441 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.441 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.441 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.441 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.441 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.441 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.441 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.441 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.441 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.441 | |
| 4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4zvn | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.441 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.440 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.440 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.440 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.440 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2yhu | WHF | Pteridine reductase | / | 0.440 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.440 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.440 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.440 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.440 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.440 | |
| 4fll | YZ6 | Methionine aminopeptidase 1 | / | 0.440 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.440 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.440 |