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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3lt2FT3Enoyl-ACP reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3lt2FT3Enoyl-ACP reductase/1.000
3lt0FT1Enoyl-ACP reductase/0.767
3am3TCLEnoyl-ACP reductase/0.713
3lt1FT2Enoyl-ACP reductase/0.690
3am5TCLEnoyl-ACP reductase/0.668
4igeCHJEnoyl-acyl carrier reductase/0.660
3am4FT1Enoyl-ACP reductase/0.653
1uh5TCLEnoyl-ACP reductase/0.635
2ol4JPNEnoyl-ACP reductase/0.624
3lsyFT0Enoyl-ACP reductase/0.623
1nhgTCLEnoyl-ACP reductase/0.618
3f4bTCLEnoyl-acyl carrier protein reductase/0.618
2o2yTCLEnoyl-ACP reductase/0.613
1nnuTCTEnoyl-ACP reductase/0.612
1zsnTN2Enoyl-ACP reductase/0.604
2foiJPAEnoyl-acyl carrier reductase/0.601
2op07PCEnoyl-ACP reductase/0.598
1zxlJP1Enoyl-ACP reductase/0.585
1nhwTCCEnoyl-ACP reductase/0.582
1zw1TN5Enoyl-ACP reductase/0.571
2o2sTCLEnoyl-acyl carrier reductase/0.559
3nj8NJ8Enoyl-acyl carrier reductase/0.543
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.532
3nrcTCLEnoyl-[acyl-carrier-protein] reductase [NADH]/0.524
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.523
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.499
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.493
3lqfNADGalactitol dehydrogenase/0.490
1pg3PRXAcetyl-coenzyme A synthetase/0.489
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.488
2hdjNDPAldo-keto reductase family 1 member C2/0.488
3fne8PCEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.485
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.484
2uzfCAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.482
3fnhJPJEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.481
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.481
3mj5GRMReplicase polyprotein 1a3.4.220.479
4dc0NDPPutative ketoacyl reductase1.3.10.478
1tl7FOKAdenylate cyclase type 2/0.477
1tl7FOKAdenylate cyclase type 5/0.477
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.477
3rbqGLY_ALA_GLY_DAOProtein unc-119 homolog A/0.477
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.476
2c29NAPDihydroflavonol 4-reductase/0.476
4ambDUDPutative glycosyl transferase/0.476
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.476
5idwNAPShort-chain dehydrogenase/reductase SDR/0.476
2z97CAMCamphor 5-monooxygenase1.14.15.10.475
4enhFVXCholesterol 24-hydroxylase/0.475
4q71FADBifunctional protein PutA/0.475
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.475
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.474
4e5yNDPGDP-L-fucose synthase1.1.1.2710.474
5koiNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.474
1pqc444Oxysterols receptor LXR-beta/0.473
2b35NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
2bd0NAPSepiapterin reductase/0.473
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.473
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.473
3o8gO8GHTH-type transcriptional regulator EthR/0.473
3ohh3HHBeta-secretase 13.4.23.460.473
2vprTDCTetracycline repressor protein class H/0.472
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.472
4g2i0VQVitamin D3 receptor/0.472
1geeNADGlucose 1-dehydrogenase1.1.1.470.471
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.471
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.471
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.470
1n5dNDPCarbonyl reductase [NADPH] 1/0.470
4zm6ACON-acetyl-beta-D glucosaminidase/0.470
5jlaNADPutative short-chain dehydrogenase/reductase/0.470
1bsvNDPGDP-L-fucose synthase/0.469
1cydNDPCarbonyl reductase [NADPH] 21.1.1.1840.469
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.469
4jtqNAPAldo-keto reductase family 1 member C2/0.469
1rwbNADGlucose 1-dehydrogenase1.1.1.470.468
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.468
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.467
1k7l544Peroxisome proliferator-activated receptor alpha/0.467
2givACOHistone acetyltransferase KAT8/0.467
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.467
1rkhVD2Vitamin D3 receptor/0.466
1x7hNDPPutative ketoacyl reductase1.3.10.466
3f1kNAPUncharacterized oxidoreductase YciK10.466
4dbzNDPPutative ketoacyl reductase1.3.10.466
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.466
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.466
2a1nCAMCamphor 5-monooxygenase1.14.15.10.465
2nsd4PIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
4qecNAPElxO/0.465
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2is0I03Beta-secretase 13.4.23.460.464
2nq8ZIDEnoyl-ACP reductase/0.464
2vbpVB1Isopenicillin N synthase1.21.3.10.464
3bg7FADPyranose 2-oxidase/0.464
3bptQUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial3.1.2.40.464
3fx4FX4Alcohol dehydrogenase [NADP(+)]1.1.1.20.464
3lpiZ74Beta-secretase 13.4.23.460.464
4jq3NAPAldo-keto reductase family 1 member C2/0.464
5cp4CAMCamphor 5-monooxygenase1.14.15.10.464
5kf8ACOPredicted acetyltransferase/0.464
1drhNAPDihydrofolate reductase1.5.1.30.463
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.463
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.463
4b0cC9H3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase4.2.1.590.463
4y93746Tyrosine-protein kinase/0.463
1bk0ACVIsopenicillin N synthase1.21.3.10.462
1gcoNADGlucose 1-dehydrogenase1.1.1.470.462
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2fznFADBifunctional protein PutA1.5.5.20.462
3lpjZ75Beta-secretase 13.4.23.460.462
4h1q0XXMatrix metalloproteinase-93.4.24.350.462
4uyf73BBromodomain-containing protein 2/0.462
1olmVTQSEC14-like protein 2/0.461
1tj1FADBifunctional protein PutA1.5.5.20.461
2ebaFADPutative glutaryl-CoA dehydrogenase/0.461
2hcdBIVVitamin D3 receptor A/0.461
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.461
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.461
3toxNAPPutative oxidoreductase/0.461
4iarERM5-hydroxytryptamine receptor 1B/0.461
1iy8NADLevodione reductase/0.460
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.460
1poxFADPyruvate oxidase1.2.3.30.460
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.460
2wsbNADGalactitol dehydrogenase/0.460
3q9tFAYUncharacterized protein/0.460
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.460
4boeCLRJapanin/0.460
4hy6FJ1Heat shock protein HSP 90-alpha/0.460
4tuvCPZCytochrome P450 1191.140.460
1n83CLRNuclear receptor ROR-alpha/0.459
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
2p2bPRXAcetyl-coenzyme A synthetase/0.459
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.459
3w5p4OAVitamin D3 receptor/0.459
4ly91YYGlucokinase regulatory protein/0.459
4ure1PSCyclohexanol dehydrogenase/0.459
4xo7NAPAldo-keto reductase family 1 member C2/0.459
1bwsNDPGDP-L-fucose synthase/0.458
1phgMYTCamphor 5-monooxygenase1.14.15.10.458
2a1mCAMCamphor 5-monooxygenase1.14.15.10.458
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.458
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.458
2zzcNAPThioredoxin reductase 1, cytoplasmic1.8.1.90.458
3iocA5DPantothenate synthetase6.3.2.10.458
3lv1NAPNAD(P)-dependent benzaldehyde dehydrogenase1.2.1.280.458
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.458
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.458
5cdgPFBAlcohol dehydrogenase E chain1.1.1.10.458
1rdt570Peroxisome proliferator-activated receptor gamma/0.457
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.457
1v35NAIEnoyl-ACP reductase/0.457
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.457
2jb4A14Isopenicillin N synthase1.21.3.10.457
2wpxACOOrf14/0.457
2yekEAMBromodomain-containing protein 2/0.457
3jzdNADMaleylacetate reductase/0.457
3kybFADUDP-galactopyranose mutase5.4.99.90.457
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.457
3stv3HOMethylketone synthase I/0.457
3up0D7SaceDAF-12/0.457
4ez30S0Cyclin-dependent kinase 22.7.11.220.457
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4k6fNAPPutative Acetoacetyl-CoA reductase/0.457
4oztP1AEcdysone receptor, putative/0.457
3sn6P0GBeta-2 adrenergic receptor/0.457
1di8DTQCyclin-dependent kinase 22.7.11.220.456
1gqtACPRibokinase/0.456
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.456
1txtCAAHMG-CoA synthase/0.456
2e1mFADL-glutamate oxidase/0.456
3qtuX44Cyclin-dependent kinase 22.7.11.220.456
3s55NADPutative short-chain dehydrogenase/reductase/0.456
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.456
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.456
4q73FADBifunctional protein PutA/0.456
1kkq471Peroxisome proliferator-activated receptor alpha/0.455
1x8lOXRRetinol dehydratase/0.455
2iw94SPCyclin-dependent kinase 22.7.11.220.455
2jh0701Prothrombin3.4.21.50.455
3gw9VNILanosterol 14-alpha-demethylase/0.455
3ijdC2FMethylenetetrahydrofolate reductase/0.455
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.455
3ioeA7DPantothenate synthetase6.3.2.10.455
3pe2E1BCasein kinase II subunit alpha2.7.11.10.455
3q0uLL3HTH-type transcriptional regulator EthR/0.455
3vjhJ35Peroxisome proliferator-activated receptor gamma/0.455
3vt8YI3Vitamin D3 receptor/0.455
4a81DXCMajor pollen allergen Bet v 1-A/0.455
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.455
4nbwNADShort-chain dehydrogenase/reductase SDR/0.455
5a0112VO-glycosyltransferase/0.455
1fxsNAPGDP-L-fucose synthase/0.454
1pq944BOxysterols receptor LXR-beta/0.454
2fnaADPUncharacterized protein/0.454
2he5NDPAldo-keto reductase family 1 member C211.1.10.454
2mm3CHOGastrotropin/0.454
2y6fM9FIsopenicillin N synthase1.21.3.10.454
2z3uCRRCytochrome P450/0.454
3gkjHC3Niemann-Pick C1 protein/0.454
1oiyN41Cyclin-dependent kinase 22.7.11.220.453
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.453
1re9DSOCamphor 5-monooxygenase1.14.15.10.453
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.453
2z1qFADAcyl-CoA dehydrogenase/0.453
3a1l2CCCytochrome P450/0.453
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.453
3gwfFADCyclohexanone monooxygenase/0.453
3q9bB3NAcetylpolyamine amidohydrolase/0.453
4emaBRLPeroxisome proliferator-activated receptor gamma/0.453
4g1z0VPVitamin D3 receptor A/0.453
4haiI23Bifunctional epoxide hydrolase 23.1.3.760.453
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.453
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1e7qNAPGDP-L-fucose synthase/0.452
1g6kNADGlucose 1-dehydrogenase1.1.1.470.452
1jioDEB6-deoxyerythronolide B hydroxylase/0.452
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.452
1w4zNAPPutative ketoacyl reductase1.3.10.452
1wlvCOAPhenylacetic acid degradation protein PaaI/0.452
2bgsNDPAldose reductase1.1.1.210.452
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.452
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.452
2wdzNADGalactitol dehydrogenase/0.452
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.452
3fcjFADNitroalkane oxidase1.7.3.10.452
3k4nFADPyranose 2-oxidase/0.452
3sufSUEPolyprotein/0.452
3w0c6DSVitamin D3 receptor/0.452
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.452
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.452
1ndhFADNADH-cytochrome b5 reductase 31.6.2.20.451
1pr9NAPL-xylulose reductase1.1.1.100.451
1xe65FPPlasmepsin-23.4.23.390.451
2acqNAPAldose reductase1.1.1.210.451
2g5cNADPrephenate dehydrogenase/0.451
2ozrGG1Collagenase 33.4.240.451
2yjxYJXHeat shock protein HSP 90-alpha/0.451
2zxgS23Aminopeptidase N3.4.11.20.451
3qm4PN0Cytochrome P450 2D6/0.451
4px9ADPATP-dependent RNA helicase DDX3X3.6.4.130.451
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.451
1axwMTXThymidylate synthase/0.450
1hk5T44Serum albumin/0.450
1o76CAMCamphor 5-monooxygenase1.14.15.10.450
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.450
1vrwNAIEnoyl-ACP reductase/0.450
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2hu637AMacrophage metalloelastase3.4.24.650.450
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2uxhQUEHTH-type transcriptional regulator TtgR/0.450
2uxpCLMHTH-type transcriptional regulator TtgR/0.450
2w4qCBWProstaglandin reductase 21.3.1.480.450
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3p3zP3ZPutative cytochrome P450/0.450
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.450
4g95OAGDihydrofolate reductase1.5.1.30.450
4li81XQTankyrase-12.4.2.300.450
4o1mNADEnoyl-acyl carrier reductase/0.450
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.450
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.450
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.450
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.450
1fmlRTLRetinol dehydratase/0.449
1gj5130Prothrombin3.4.21.50.449
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.449
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.449
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.449
2p83MR0Beta-secretase 13.4.23.460.449
2vu3LZECyclin-dependent kinase 22.7.11.220.449
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.449
3r7eX88Cyclin-dependent kinase 22.7.11.220.449
3uli1N3Cyclin-dependent kinase 22.7.11.220.449
4acm7YGCyclin-dependent kinase 22.7.11.220.449
4dpf0LGBeta-secretase 13.4.23.460.449
4g1y0VOVitamin D3 receptor A/0.449
4mlp2CXCryptochrome-2/0.449
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.449
5kj1PFBAlcohol dehydrogenase E chain1.1.1.10.449
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1k8cNAPNAD(P)H-dependent D-xylose reductase1.1.1.3070.448
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.448
1pjcNADAlanine dehydrogenase/0.448
2e48FADD-amino-acid oxidase1.4.3.30.448
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.448
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.448
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.448
2ylrFADPhenylacetone monooxygenase1.14.13.920.448
3cic316Beta-secretase 13.4.23.460.448
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3qlrNDPDihydrofolate reductase1.5.1.30.448
3qxpX64Cyclin-dependent kinase 22.7.11.220.448
3r354CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
3vtbTKAVitamin D3 receptor/0.448
4b8wNAPGDP-L-fucose synthase1.1.1.2710.448
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.448
4dsgFADUncharacterized protein/0.448
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.448
4fko20KCyclin-dependent kinase 22.7.11.220.448
4gevCB3Thymidylate synthase/0.448
4jx1CAHCamphor 5-monooxygenase1.14.15.10.448
4kgkGTPUncharacterized protein/0.448
4l1xNAPAldo-keto reductase family 1 member C2/0.448
4lisNADUDP-glucose 4-epimerase (Eurofung)/0.448
5kf9ACOPredicted acetyltransferase/0.448
1bygSTUTyrosine-protein kinase CSK/0.447
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1hb3SCVIsopenicillin N synthase1.21.3.10.447
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.447
1oi9N20Cyclin-dependent kinase 22.7.11.220.447
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.447
2iviACWIsopenicillin N synthase1.21.3.10.447
2j83BATUlilysin3.4.240.447
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.447
3ai2NDPNADPH-sorbose reductase/0.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3tdaPN0Cytochrome P450 2D6/0.447
3ua108YCytochrome P450 3A4/0.447
3x2fNAIAdenosylhomocysteinase/0.447
4bfpSWYTankyrase-22.4.2.300.447
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.447
4fqsLYAThymidylate synthase ThyA/0.447
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.447
4tvbNADHomospermidine synthase2.5.1.440.447
5byuCOAThioesterase/0.447
1ae1NAPTropinone reductase 1/0.446
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1kceCB3Thymidylate synthase/0.446
1ppjANYCytochrome b/0.446
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.446
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.446
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
2vn0TDZCytochrome P450 2C8/0.446
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3ln3NADAldo-keto reductase family 1 member C13/0.446
3uylTYDProbable NDP-rhamnosyltransferase/0.446
3vg10GTBeta-secretase 13.4.23.460.446
3vtcTK3Vitamin D3 receptor/0.446
4aosFADSteroid monooxygenase/0.446
4gh5NADShort-chain dehydrogenase/reductase SDR/0.446
4rvj478Protease/0.446
4trj665Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4yntFDAGlucose oxidase, putative/0.446
5dbvCOAAldehyde Dehydrogenase/0.446
5kghACOPredicted acetyltransferase/0.446
1aiqCB3Thymidylate synthase/0.445
1dkfBMSRetinoic acid receptor alpha/0.445
1kevNDPNADP-dependent isopropanol dehydrogenase1.1.1.800.445
1obnASVIsopenicillin N synthase1.21.3.10.445
1snyNAPLD36273p/0.445
2i1vADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.445
2x3nFADProbable FAD-dependent monooxygenase/0.445
2xnbY8LCyclin-dependent kinase 22.7.11.220.445
3clrFADElectron transfer flavoprotein subunit alpha/0.445
3lpkZ76Beta-secretase 13.4.23.460.445
3pndFADFAD:protein FMN transferase/0.445
3slkNDPPolyketide synthase extender module 2/0.445
3tp0FO5HTH-type transcriptional regulator EthR/0.445
4b8zNAPGDP-L-fucose synthase1.1.1.2710.445
4dru0LNGenome polyprotein2.7.7.480.445
4l4dCAMCamphor 5-monooxygenase1.14.15.10.445
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
4rupH97Vitamin D3 receptor A/0.445
5f8eSAHPossible transcriptional regulatory protein/0.445
5kj6NAJAlcohol dehydrogenase E chain1.1.1.10.445
1dr3TAPDihydrofolate reductase1.5.1.30.444
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1powFADPyruvate oxidase1.2.3.30.444
1r78FMDCyclin-dependent kinase 22.7.11.220.444
1s7nCOAAcetyl transferase/0.444
1w6hTITPlasmepsin-23.4.23.390.444
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2a94AP0L-lactate dehydrogenase1.1.1.270.444
2btsU32Cyclin-dependent kinase 22.7.11.220.444
2feuCAMCamphor 5-monooxygenase1.14.15.10.444
2w71L23Biotin carboxylase6.3.4.140.444
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.444
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3dv5BAVBeta-secretase 13.4.23.460.444
3lshFADPyranose 2-oxidase/0.444
3mdmFJZCholesterol 24-hydroxylase/0.444
3qgd26SGenome polyprotein2.7.7.480.444
3qlsNDPDihydrofolate reductase1.5.1.30.444
3t2yFADSulfide-quinone reductase/0.444
4an4DUDPutative glycosyl transferase/0.444
4fhh0U3Vitamin D3 receptor A/0.444
4fkpLS5Cyclin-dependent kinase 22.7.11.220.444
4g20484Vitamin D3 receptor A/0.444
4g7gVFVLanosterol 14-alpha-demethylase/0.444
4i0h1BLBeta-secretase 13.4.23.460.444
4i8vBHFCytochrome P450 1A11.14.14.10.444
4nbuNAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.444
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.444
5dmhADP3-oxo-tetronate kinase/0.444
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.444
5hynSAHHistone-lysine N-methyltransferase EZH22.1.1.430.444
5kcpNAJAlcohol dehydrogenase E chain1.1.1.10.444
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1iwiCAMCamphor 5-monooxygenase1.14.15.10.443
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.443
2du8FADD-amino-acid oxidase1.4.3.30.443
2f3eAXQBeta-secretase 13.4.23.460.443
2fzwNADAlcohol dehydrogenase class-31.1.1.10.443
2p2jPRXAcetyl-coenzyme A synthetase/0.443
2pg0FADAcyl-CoA dehydrogenase/0.443
2vkeTACTetracycline repressor protein class D/0.443
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.443
2xgoZKDUncharacterized protein/0.443
3awiFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC1.50.443
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.443
3fwgCAMCamphor 5-monooxygenase1.14.15.10.443
3g1oRF1HTH-type transcriptional regulator EthR/0.443
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3r9hZ67Cyclin-dependent kinase 22.7.11.220.443
3vt9YI4Vitamin D3 receptor/0.443
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.443
4j7uNAPSepiapterin reductase1.1.1.1530.443
4jl6ADPAdenylate kinase/0.443
4l0qNADAlcohol dehydrogenase class-3/0.443
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.443
4xr9TMPCalS8/0.443
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.443
5irnADPNucleotide binding oligomerization domain containing 2/0.443
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.443
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.442
1nzdUPGDNA beta-glucosyltransferase/0.442
1wntNAPL-xylulose reductase1.1.1.100.442
1xs7MMIBeta-secretase 13.4.23.460.442
1yrdCAMCamphor 5-monooxygenase1.14.15.10.442
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2ca0PXICytochrome P450 monooxygenase PikC/0.442
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.442
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.442
2y60M8FIsopenicillin N synthase1.21.3.10.442
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.442
3gy0NAPNAD(P)-dependent oxidoreductase/0.442
3ntaCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.442
3ox4NADAlcohol dehydrogenase 21.1.1.10.442
3q43D66M1 family aminopeptidase3.4.110.442
3rpv26ZCyclin-dependent kinase 22.7.11.220.442
3sp9IL2Peroxisome proliferator-activated receptor delta/0.442
3uwlFOZThymidylate synthase/0.442
3v9v21LPeroxisome proliferator-activated receptor gamma/0.442
3vdqNAD3-hydroxybutyrate dehydrogenase/0.442
4ceqQCHIntegrase/0.442
4iteTEYVitamin D3 receptor/0.442
4lxa1YSBeta-secretase 13.4.23.460.442
4n4t2GVTankyrase-12.4.2.300.442
4qi5FADCellobiose dehydrogenase/0.442
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.442
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.442
1e1lFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.441
1mi3NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.441
1o2g696Prothrombin3.4.21.50.441
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.441
2lbaCHOFatty acid binding protein 6/0.441
3fwfCAMCamphor 5-monooxygenase1.14.15.10.441
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3lpgZ78Beta-glucuronidase3.2.1.310.441
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.441
3pqbVGPPutative oxidoreductase/0.441
3tk3CPZCytochrome P450 2B41.14.14.10.441
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.441
3unj0BXCyclin-dependent kinase 22.7.11.220.441
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.441
3v9y24LPeroxisome proliferator-activated receptor gamma/0.441
4gl4NAIAlcohol dehydrogenase class-3/0.441
4lcjNADC-terminal-binding protein 2/0.441
4q72FADBifunctional protein PutA/0.441
5jscFADPutative acyl-CoA dehydrogenase/0.441
1e3eNAIAlcohol dehydrogenase 41.1.1.10.440
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1n06ADPRiboflavin kinase2.7.1.260.440
1ozhHE3Acetolactate synthase, catabolic2.2.1.60.440
1qiqACCIsopenicillin N synthase1.21.3.10.440
1ye6NADNAD(P)H-dependent D-xylose reductase1.1.1.3070.440
1zeoC01Peroxisome proliferator-activated receptor gamma/0.440
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.440
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.440
2ptfFMNUncharacterized protein MTH_863/0.440
2vcmM11Isopenicillin N synthase1.21.3.10.440
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.440
2ylxFADPhenylacetone monooxygenase1.14.13.920.440
2ylzFADPhenylacetone monooxygenase1.14.13.920.440
3e2sFADBifunctional protein PutA1.5.5.20.440
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.440
3r2fPB0Beta-secretase 13.4.23.460.440
3rk507ZCyclin-dependent kinase 22.7.11.220.440
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.440
3w32W32Epidermal growth factor receptor2.7.10.10.440
4bb3KKAIsopenicillin N synthase1.21.3.10.440
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4dc1NDPPutative ketoacyl reductase1.3.10.440
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.440
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.440
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.440
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.440
3emlZMAAdenosine receptor A2a/0.440