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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3k3kA8SAbscisic acid receptor PYR1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3k3kA8SAbscisic acid receptor PYR1/1.000
4lgaA2OAbscisic acid receptor PYL2/0.647
3zvuA8SAbscisic acid receptor PYR1/0.618
3kdiA8SAbscisic acid receptor PYL2/0.612
3njoPYVAbscisic acid receptor PYR1/0.612
3ujlA8SAbscisic acid receptor PYL2/0.611
3kb3A8SAbscisic acid receptor PYL2/0.610
3k90A8SAbscisic acid receptor PYR1/0.605
3nmnPYVAbscisic acid receptor PYL1/0.601
3negPYVAbscisic acid receptor PYL1/0.592
3njoP2MAbscisic acid receptor PYR1/0.592
3kb0A8SAbscisic acid receptor PYL2/0.589
4lg5A1OAbscisic acid receptor PYL2/0.586
3qn1A8SAbscisic acid receptor PYR1/0.583
4oicA8SBet v I allergen-like/0.582
3kdjA8SAbscisic acid receptor PYL1/0.581
4jdaA9SAbscisic acid receptor PYL3/0.579
4ds8A8SAbscisic acid receptor PYL3/0.576
4la7A1OAbscisic acid receptor PYL2/0.568
3nefPYVAbscisic acid receptor PYL1/0.561
3nj0PYVAbscisic acid receptor PYL2/0.545
3r6pA8SAbscisic acid receptor PYL10/0.540
3nmhPYVAbscisic acid receptor PYL2/0.535
4dscA8SAbscisic acid receptor PYL3/0.534
3oquA8SAbscisic acid receptor PYL9/0.532
3nmvPYVAbscisic acid receptor PYL2/0.530
3w9rA8SAbscisic acid receptor PYL9/0.529
3nmpPYVAbscisic acid receptor PYL2/0.518
3ojiPYVAbscisic acid receptor PYL3/0.513
3ns2PYVAbscisic acid receptor PYL2/0.510
4dsbA8SAbscisic acid receptor PYL3/0.507
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.505
4fhi0S4Vitamin D3 receptor A/0.505
4cdmFO1Deoxyribodipyrimidine photolyase/0.495
4m2xTMQDihydrofolate reductase1.5.1.30.495
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.494
3vrwYS5Vitamin D3 receptor/0.492
2a1nCAMCamphor 5-monooxygenase1.14.15.10.490
4kak06UDihydrofolate reductase1.5.1.30.489
1t88CAMCamphor 5-monooxygenase1.14.15.10.488
2rhrEMOPutative ketoacyl reductase1.3.10.487
4c9pCAMCytochrome P450/0.487
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.485
2wotZZGTGF-beta receptor type-12.7.11.300.484
3qlzQLZUncharacterized protein/0.484
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.483
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.483
3vt5YI2Vitamin D3 receptor/0.483
4h9506UDihydrofolate reductase1.5.1.30.483
2qblCAMCamphor 5-monooxygenase1.14.15.10.482
2zlcVDXVitamin D3 receptor/0.482
4h9814QUncharacterized protein/0.482
4xe606UDihydrofolate reductase1.5.1.30.482
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.481
2zbaZBATrichothecene 3-O-acetyltransferase/0.481
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.480
3tijURINucleoside permease/0.480
1gs4ZK5Androgen receptor/0.479
1jx0DFVChalcone--flavonone isomerase 15.5.1.60.479
4xdmGDMHeat shock cognate 90 kDa protein/0.479
1ly4COQDihydrofolate reductase1.5.1.30.477
2wo7ASVIsopenicillin N synthase1.21.3.10.477
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.477
3cseN22Uncharacterized protein/0.476
3fwjCAMCamphor 5-monooxygenase1.14.15.10.476
3vt65YIVitamin D3 receptor/0.476
3w5rLOAVitamin D3 receptor/0.476
6cp4CAMCamphor 5-monooxygenase1.14.15.10.475
1rkhVD2Vitamin D3 receptor/0.474
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.474
3nr4PYVAbscisic acid receptor PYL2/0.474
1s0zEB1Vitamin D3 receptor/0.473
3eek53SUncharacterized protein/0.473
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.473
1ot7CHCBile acid receptor/0.472
1rk3VDXVitamin D3 receptor/0.472
3bl7DD1m7GpppX diphosphatase3.6.1.590.472
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.472
5k2cZMAAdenosine receptor A2a/0.472
1upw444Oxysterols receptor LXR-beta/0.471
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.471
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
3zk5Z18Cytochrome P450 monooxygenase PikC/0.471
4kfj1R0Dihydrofolate reductase1.5.1.30.471
1ia1TQ3Dihydrofolate reductase1.5.1.30.470
2qboCAMCamphor 5-monooxygenase1.14.15.10.470
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.470
3a783EVVitamin D3 receptor/0.470
3zkyWT4Isopenicillin N synthase1.21.3.10.470
3zoiM2WIsopenicillin N synthase1.21.3.10.470
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.469
2o4rVD5Vitamin D3 receptor/0.469
2wouZZFTGF-beta receptor type-12.7.11.300.469
3fwfCAMCamphor 5-monooxygenase1.14.15.10.469
4jlm1NNDeoxycytidine kinase2.7.1.740.469
4pd5GEONucleoside permease/0.469
5cccDDFDihydrofolate reductase1.5.1.30.469
1db1VDXVitamin D3 receptor/0.468
1og5SWFCytochrome P450 2C9/0.468
1rx2FOLDihydrofolate reductase1.5.1.30.468
3ielU5PRibonuclease TTHA02523.10.468
3lxiCAMCytochrome P450/0.468
3pe6ZYHMonoglyceride lipase/0.468
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.468
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.468
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.468
4pb25UDNucleoside permease/0.468
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.467
1jpaANPEphrin type-B receptor 22.7.10.10.467
3w0iO11Vitamin D3 receptor/0.467
4gueQCTRibosomal protein S6 kinase alpha-32.7.11.10.467
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.467
1dhjMTXDihydrofolate reductase1.5.1.30.466
1m17AQ4Epidermal growth factor receptor2.7.10.10.466
1nq7ARLNuclear receptor ROR-beta/0.466
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.466
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.466
4ruoBIVVitamin D3 receptor A/0.466
1lhwESMSex hormone-binding globulin/0.465
1q4xG24Thyroid hormone receptor beta/0.465
2fypRDEEndoplasmin/0.465
2hasC3OVitamin D3 receptor/0.465
2hb8MVDVitamin D3 receptor/0.465
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.465
3eej53RUncharacterized protein/0.465
4g1d0VKVitamin D3 receptor A/0.465
1dz8CAMCamphor 5-monooxygenase1.14.15.10.464
1hnvTBOGag-Pol polyprotein2.7.7.490.464
1klkPMDDihydrofolate reductase1.5.1.30.464
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
1txiTX5Vitamin D3 receptor/0.464
1uy8PU5Heat shock protein HSP 90-alpha/0.464
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
2b5vNAPGlucose 1-dehydrogenase/0.464
3fwiCAMCamphor 5-monooxygenase1.14.15.10.464
4eqcXR1Serine/threonine-protein kinase PAK 12.7.11.10.464
4ia1BIVVitamin D3 receptor A/0.464
4ia2BIVVitamin D3 receptor A/0.464
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.464
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.463
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
1l2jETCEstrogen receptor beta/0.463
2eb3ANPEpidermal growth factor receptor2.7.10.10.463
2hb7O1CVitamin D3 receptor/0.463
3c11GDMATP-dependent molecular chaperone HSP82/0.463
4deg0JJHepatocyte growth factor receptor2.7.10.10.463
4g1z0VPVitamin D3 receptor A/0.463
4g20484Vitamin D3 receptor A/0.463
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.463
4hnc0UTMandelate racemase/0.463
4ixgIXGDihydrofolate reductase1.5.1.30.463
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.462
3l8sBFFMitogen-activated protein kinase 14/0.462
4g3rCAMCamphor 5-monooxygenase1.14.15.10.462
4gg70J8Hepatocyte growth factor receptor2.7.10.10.462
4iteTEYVitamin D3 receptor/0.462
4l9kEHFSerum albumin/0.462
1phePIYCamphor 5-monooxygenase1.14.15.10.461
1zg32HIIsoflavone 4'-O-methyltransferase/0.461
2exlGDMEndoplasmin/0.461
2harOCCVitamin D3 receptor/0.461
2q70DC8Estrogen receptor/0.461
2vcmM11Isopenicillin N synthase1.21.3.10.461
3fp0FP015-O-acetyltransferase/0.461
3fwgCAMCamphor 5-monooxygenase1.14.15.10.461
3kpzZNEVitamin D3 receptor/0.461
3w0jT08Vitamin D3 receptor/0.461
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.461
4pd6URINucleoside permease/0.461
4py6R78Bromodomain protein, putative/0.461
1dhiMTXDihydrofolate reductase1.5.1.30.460
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.460
2hcdBIVVitamin D3 receptor A/0.460
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.460
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.460
4i2pG73Gag-Pol polyprotein2.7.7.490.460
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.460
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
1h1pCMGCyclin-dependent kinase 22.7.11.220.459
1ie8KH1Vitamin D3 receptor/0.459
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1o76CAMCamphor 5-monooxygenase1.14.15.10.459
2feuCAMCamphor 5-monooxygenase1.14.15.10.459
3d90NOGProgesterone receptor/0.459
3ntz3TZDihydrofolate reductase1.5.1.30.459
3sh25DRDihydrofolate reductase1.5.1.30.459
3uvp048Mitogen-activated protein kinase 14/0.459
4a9mP9MBromodomain-containing protein 2/0.459
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4ek1CAMCamphor 5-monooxygenase1.14.15.10.459
4ifvT27Gag-Pol polyprotein2.7.7.490.459
4xivACPChemotaxis protein CheA2.7.13.30.459
5k2aZMAAdenosine receptor A2a/0.459
1bozPRDDihydrofolate reductase1.5.1.30.458
1m7aMQUDihydrofolate reductase1.5.1.30.458
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.458
1t87CAMCamphor 5-monooxygenase1.14.15.10.458
1um0FMNChorismate synthase/0.458
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
2fai459Estrogen receptor/0.458
2vwcBC2ATP-dependent molecular chaperone HSP82/0.458
3d574HYThyroid hormone receptor beta/0.458
3gobHXXDdmC/0.458
3lfcZ86Mitogen-activated protein kinase 14/0.458
3sjzGNPTranslation initiation factor 2 subunit gamma/0.458
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.458
4kxl6C62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.458
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.458
1ie9VDXVitamin D3 receptor/0.457
1m78CLZDihydrofolate reductase1.5.1.30.457
1m9k7NINitric oxide synthase, endothelial1.14.13.390.457
1rx8FOLDihydrofolate reductase1.5.1.30.457
1uyuCAMCamphor 5-monooxygenase1.14.15.10.457
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2vn0TDZCytochrome P450 2C8/0.457
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.457
2y60M8FIsopenicillin N synthase1.21.3.10.457
3gwuSRENa(+):neurotransmitter symporter (Snf family)/0.457
3k47D09Dihydrofolate reductase1.5.1.30.457
3l70JZVCytochrome b/0.457
3mdvCL6Cholesterol 24-hydroxylase/0.457
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3qlrQLRDihydrofolate reductase1.5.1.30.457
3vtcTK3Vitamin D3 receptor/0.457
4g2h0VQVitamin D3 receptor A/0.457
4hlwTESAndrogen receptor/0.457
4pdaCTNNucleoside permease/0.457
4rupH97Vitamin D3 receptor A/0.457
4z07PCGcGMP-dependent protein kinase 12.7.11.120.457
1oc1ASVIsopenicillin N synthase1.21.3.10.456
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.456
1s19MC9Vitamin D3 receptor/0.456
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.456
1uzwCDHIsopenicillin N synthase1.21.3.10.456
2w6oOA3Biotin carboxylase6.3.4.140.456
3gwfFADCyclohexanone monooxygenase/0.456
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.456
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4g1y0VOVitamin D3 receptor A/0.456
4kwi1TJReductase homolog/0.456
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.456
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.456
4mv4ACPBiotin carboxylase6.3.4.140.456
4rbs0RVMetallo-beta-lactamase type 2/0.456
3emlZMAAdenosine receptor A2a/0.456
1hb3SCVIsopenicillin N synthase1.21.3.10.455
1t65DHTAndrogen receptor/0.455
1x7rGENEstrogen receptor/0.455
1xp9AIJEstrogen receptor/0.455
1yrdCAMCamphor 5-monooxygenase1.14.15.10.455
2a1oCAMCamphor 5-monooxygenase1.14.15.10.455
2b1z17MEstrogen receptor/0.455
2pklDHTAndrogen receptor/0.455
2vwv7X3Ephrin type-B receptor 42.7.10.10.455
3c14FOKAdenylate cyclase type 2/0.455
3c14FOKAdenylate cyclase type 5/0.455
3i8aN22Dihydrofolate reductase1.5.1.30.455
3m7rVDXVitamin D3 receptor/0.455
3ua506XCytochrome P450 2B61.14.130.455
3vt7VDXVitamin D3 receptor/0.455
4bfvZVVPantothenate kinase2.7.1.330.455
4cukNAID-lactate dehydrogenase/0.455
4ia7BIVVitamin D3 receptor A/0.455
4ivy1GTEstrogen receptor/0.455
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.455
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.455
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.454
1s6qTPBGag-Pol polyprotein2.7.7.490.454
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
2o4jVD4Vitamin D3 receptor/0.454
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.454
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.454
3jziJZLBiotin carboxylase6.3.4.140.454
3l63CAMCamphor 5-monooxygenase1.14.15.10.454
3lamKRPGag-Pol polyprotein2.7.7.490.454
1aoeGW3Dihydrofolate reductase1.5.1.30.453
1dz4CAMCamphor 5-monooxygenase1.14.15.10.453
1gebCAMCamphor 5-monooxygenase1.14.15.10.453
1hfqMOTDihydrofolate reductase1.5.1.30.453
1owlFADDeoxyribodipyrimidine photo-lyase4.1.99.30.453
1rkgVD1Vitamin D3 receptor/0.453
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.453
2esaGDMEndoplasmin/0.453
2jn3JN3Fatty acid-binding protein, liver/0.453
2vw5BC6ATP-dependent molecular chaperone HSP82/0.453
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.453
3ddw055Glycogen phosphorylase, liver form2.4.1.10.453
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.453
3vt8YI3Vitamin D3 receptor/0.453
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4eipK2CPutative FAD-monooxygenase/0.453
5h8tRTLRetinol-binding protein 1/0.453
5hyrESTEstrogen receptor/0.453
5kghACOPredicted acetyltransferase/0.453
1bwsNDPGDP-L-fucose synthase/0.452
1dz6CAMCamphor 5-monooxygenase1.14.15.10.452
1phgMYTCamphor 5-monooxygenase1.14.15.10.452
1t76DHTAndrogen receptor/0.452
1t85CAMCamphor 5-monooxygenase1.14.15.10.452
1uofPNNDeacetoxycephalosporin C synthase1.14.20.10.452
2jb4A14Isopenicillin N synthase1.21.3.10.452
2y30SM8Putative repressor SimReg2/0.452
3h18PMSEsterase/lipase/0.452
3qly55VUncharacterized protein/0.452
3r336MEDihydrofolate reductase1.5.1.30.452
3vt45YIVitamin D3 receptor/0.452
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.452
4iu71GMEstrogen receptor/0.452
4iyg1HUStrictosidine synthase4.3.3.20.452
4nc3ERM5-hydroxytryptamine receptor 2B/0.452
1cqp803Integrin alpha-L/0.451
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1f5fDHTSex hormone-binding globulin/0.451
1qknRALEstrogen receptor beta/0.451
1s3wTQTDihydrofolate reductase1.5.1.30.451
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.451
2jfaRALEstrogen receptor/0.451
2pioDHTAndrogen receptor/0.451
2q9fC3SCholesterol 24-hydroxylase/0.451
2ykcYKCHeat shock protein HSP 90-alpha/0.451
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.451
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.451
3pe2E1BCasein kinase II subunit alpha2.7.11.10.451
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
3qj5022Alcohol dehydrogenase class-31.1.1.10.451
3vrvYSDVitamin D3 receptor/0.451
3vtdTKDVitamin D3 receptor/0.451
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ffrATPUncharacterized protein/0.451
4ia3BIVVitamin D3 receptor A/0.451
4itfTFYVitamin D3 receptor/0.451
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.451
4l4fCAMCamphor 5-monooxygenase1.14.15.10.451
1f20FADNitric oxide synthase, brain1.14.13.390.450
1t86CAMCamphor 5-monooxygenase1.14.15.10.450
1x7jGENEstrogen receptor beta/0.450
1yrcCAMCamphor 5-monooxygenase1.14.15.10.450
2cd2FOLDihydrofolate reductase1.5.1.30.450
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.450
2m56CAMCamphor 5-monooxygenase1.14.15.10.450
3bfa9ODOdorant binding protein ASP1/0.450
3egvSAHRibosomal protein L11 methyltransferase2.1.10.450
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
3td8D2RDihydrofolate reductase1.5.1.30.450
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.450
3vruYS3Vitamin D3 receptor/0.450
3vt3VDXVitamin D3 receptor/0.450
4bb3KKAIsopenicillin N synthase1.21.3.10.450
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.450
4c9oCAMCytochrome P450/0.450
4i1nFOLDihydrofolate reductase1.5.1.30.450
4v12POGMaoC like domain protein/0.450
1i58ACPChemotaxis protein CheA2.7.13.30.449
1oh0EQUSteroid Delta-isomerase5.3.3.10.449
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.449
1rx3MTXDihydrofolate reductase1.5.1.30.449
1sr7MOFProgesterone receptor/0.449
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1u3r338Estrogen receptor beta/0.449
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2cciATPCyclin-dependent kinase 22.7.11.220.449
2w3aTOPDihydrofolate reductase1.5.1.30.449
2zjwREFCasein kinase II subunit alpha2.7.11.10.449
2zlaVDBVitamin D3 receptor/0.449
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.449
3drcMTXDihydrofolate reductase1.5.1.30.449
3lnbCOAN-acetyltransferase family protein/0.449
3qlwN22Dihydrofolate reductase1.5.1.30.449
3wrjCAMCamphor 5-monooxygenase1.14.15.10.449
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.449
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4f700STCyclin-dependent kinase 82.7.11.220.449
4fflADPUncharacterized protein/0.449
4h9753SDihydrofolate reductase1.5.1.30.449
4i7fNVEGag-Pol polyprotein2.7.7.490.449
4kkyCAMCamphor 5-monooxygenase1.14.15.10.449
4o761M3Bromodomain-containing protein 4/0.449
4yqfGDPSeptin-9/0.449
1m79MQ1Dihydrofolate reductase1.5.1.30.448
1osfKOSHeat shock protein HSP 90-alpha/0.448
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1tl7FOKAdenylate cyclase type 2/0.448
1tl7FOKAdenylate cyclase type 5/0.448
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.448
2a1mCAMCamphor 5-monooxygenase1.14.15.10.448
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2gm12AZKinesin-like protein KIF11/0.448
2pixDHTAndrogen receptor/0.448
2zawCAMCamphor 5-monooxygenase1.14.15.10.448
2zaxCAMCamphor 5-monooxygenase1.14.15.10.448
2ze2T27Gag-Pol polyprotein2.7.7.490.448
3gc9B45Mitogen-activated protein kinase 112.7.11.240.448
3hz5Z64Heat shock protein HSP 90-alpha/0.448
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3l0lHC3Nuclear receptor ROR-gamma/0.448
3qm4PN0Cytochrome P450 2D6/0.448
3w0hW12Vitamin D3 receptor/0.448
3w33W19Epidermal growth factor receptor2.7.10.10.448
3w5p4OAVitamin D3 receptor/0.448
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4cp4CAMCamphor 5-monooxygenase1.14.15.10.448
4g2i0VQVitamin D3 receptor/0.448
4inb1F6Gag protein/0.448
4lsjLSJGlucocorticoid receptor/0.448
4yswNAIXanthine dehydrogenase/oxidase/0.448
5eg3ACPFibroblast growth factor receptor 2/0.448
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1kyoSMACytochrome b/0.447
1m8h6NINitric oxide synthase, inducible1.14.13.390.447
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.447
1py5PY1TGF-beta receptor type-12.7.11.300.447
1sn0T44Transthyretin/0.447
1tduDURThymidylate synthase/0.447
1tezHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.447
1uykPUXHeat shock protein HSP 90-alpha/0.447
1wxyFRKAdenosine deaminase3.5.4.40.447
2b55D31Cyclin-dependent kinase 22.7.11.220.447
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.447
2w3wVG9Dihydrofolate reductase/0.447
3cppCAMCamphor 5-monooxygenase1.14.15.10.447
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3u8dU8DPhospholipase A2, membrane associated/0.447
3vg9ZMAAdenosine receptor A2a/0.447
3wrlCAMCamphor 5-monooxygenase1.14.15.10.447
4asg814ATP-dependent molecular chaperone HSP82/0.447
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.447
4dfrMTXDihydrofolate reductase1.5.1.30.447
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.447
4ejh0QACytochrome P450 2A131.14.14.10.447
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4ixeIXEDihydrofolate reductase1.5.1.30.447
4nm9FADBifunctional protein PutA/0.447
4oal245Cytokinin dehydrogenase 4/0.447
1dg7WRBDihydrofolate reductase1.5.1.30.446
1e3kR18Progesterone receptor/0.446
1jioDEB6-deoxyerythronolide B hydroxylase/0.446
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.446
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
2f2cAP9Cyclin-dependent kinase 62.7.11.220.446
2hbhXE4Vitamin D3 receptor A/0.446
2oaxSNLMineralocorticoid receptor/0.446
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
3chwATPMajor actin/0.446
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3dmjGWEPol protein/0.446
3jrxS1AAcetyl-CoA carboxylase 2/0.446
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3meeT27Gag-Pol polyprotein2.7.7.490.446
3n8nN883-dehydroquinate dehydratase4.2.1.100.446
3vrtYS2Vitamin D3 receptor/0.446
4egnTWOCytochrome P450/0.446
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
4l4aCAMCamphor 5-monooxygenase1.14.15.10.446
5hs1VORLanosterol 14-alpha demethylase/0.446
5jqbIBPEnvelope glycoprotein/0.446
1culFOKAdenylate cyclase type 2/0.445
1culFOKAdenylate cyclase type 5/0.445
1dj3GDPAdenylosuccinate synthetase, chloroplastic/0.445
1h1q2A6Cyclin-dependent kinase 22.7.11.220.445
1osvCHCBile acid receptor/0.445
1p8dCO1Oxysterols receptor LXR-beta/0.445
1yinCM3Estrogen receptor/0.445
2hc4VDXVitamin D3 receptor A/0.445
2hl0A3SThreonine--tRNA ligase6.1.1.30.445
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.445
2ouzC3DEstrogen receptor/0.445
2ovhAS0Progesterone receptor/0.445
2qbmCAMCamphor 5-monooxygenase1.14.15.10.445
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.445
2yx6ADPUncharacterized protein/0.445
3bqdDAYGlucocorticoid receptor/0.445
3c3eFO12-phospho-L-lactate transferase/0.445
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.445
3nnuEDBMitogen-activated protein kinase 14/0.445
3pffADPATP-citrate synthase2.3.3.80.445
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3t3q9PLCytochrome P450 2A61.14.130.445
3w6hAZMCarbonic anhydrase 14.2.1.10.445
3wsbRWZFarnesyltransferase, putative/0.445
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4h9614QDihydrofolate reductase1.5.1.30.445
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.445
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.445
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.445
4mv8ACPBiotin carboxylase6.3.4.140.445
5prcATZReaction center protein L chain/0.445
5k2bZMAAdenosine receptor A2a/0.445
1d2sDHTSex hormone-binding globulin/0.444
1fm69CRRetinoic acid receptor RXR-alpha/0.444
1k6pXN3Gag-Pol polyprotein3.4.23.160.444
1rx6DDFDihydrofolate reductase1.5.1.30.444
2c31ADPOxalyl-CoA decarboxylase4.1.1.80.444
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.444
2gpvOHTEstrogen-related receptor gamma/0.444
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2q7kTESAndrogen receptor/0.444
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.444
2xanANPInositol-pentakisphosphate 2-kinase2.7.1.1580.444
3d75NBBPheromone-binding protein ASP1/0.444
3gcuR48Mitogen-activated protein kinase 14/0.444
3i0rRT3Gag-Pol polyprotein2.7.7.490.444
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.444
3p5kP5KMitogen-activated protein kinase 14/0.444
3p62FMNPentaerythritol tetranitrate reductase/0.444
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.444
3wowANPCasein kinase II subunit alpha2.7.11.10.444
4b1fKRHGlutamate racemase/0.444
4bbgV02Kinesin-like protein KIF11/0.444
4fhh0U3Vitamin D3 receptor A/0.444
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4k7aDHTAndrogen receptor/0.444
4l4dCAMCamphor 5-monooxygenase1.14.15.10.444
1ezfIN0Squalene synthase2.5.1.210.443
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.443
1ikxPNUGag-Pol polyprotein2.7.7.490.443
1iwjCAMCamphor 5-monooxygenase1.14.15.10.443
1qiqACCIsopenicillin N synthase1.21.3.10.443
1qjfACSIsopenicillin N synthase1.21.3.10.443
1s9qOHTEstrogen-related receptor gamma/0.443
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.443
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2pmdGNPTranslation initiation factor 2 subunit gamma/0.443
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2qocANPEphrin type-A receptor 32.7.10.10.443
2vd5BI8Myotonin-protein kinase2.7.11.10.443
2w2lNADD-mandelate dehydrogenase/0.443
2z97CAMCamphor 5-monooxygenase1.14.15.10.443
2zl9VDAVitamin D3 receptor/0.443
3d8vUD1Bifunctional protein GlmU/0.443
3gwfNAPCyclohexanone monooxygenase/0.443
3hz142CHeat shock protein HSP 90-alpha/0.443
3ixp834Ecdysone receptor/0.443
3o153NMThiamine-phosphate synthase/0.443
3oafOAGDihydrofolate reductase1.5.1.30.443
3ollESTEstrogen receptor beta/0.443
3p8iFMNPentaerythritol tetranitrate reductase/0.443
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4dpy2P0Mevalonate diphosphate decarboxylase/0.443
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.443
4wzyATPMaltokinase2.7.1.1750.443
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.443
5cp4CAMCamphor 5-monooxygenase1.14.15.10.443
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
1ao8MTXDihydrofolate reductase1.5.1.30.442
1blzACVIsopenicillin N synthase1.21.3.10.442
1draMTXDihydrofolate reductase1.5.1.30.442
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1jolFFODihydrofolate reductase1.5.1.30.442
1rjkVDZVitamin D3 receptor/0.442
1t63DHTAndrogen receptor/0.442
1w06W05Isopenicillin N synthase1.21.3.10.442
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.442
2g44T3OEstrogen receptor/0.442
2hamC33Vitamin D3 receptor/0.442
2hk51BMTyrosine-protein kinase HCK2.7.10.20.442
2p1v5TNRetinoic acid receptor RXR-alpha/0.442
2zb45OPProstaglandin reductase 21.3.1.480.442
3ft8MOJHeat shock protein HSP 90-alpha/0.442
3h3sH15Collagen type IV alpha-3-binding protein/0.442
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.442
3nxoD2BDihydrofolate reductase1.5.1.30.442
3wrmCAMCamphor 5-monooxygenase1.14.15.10.442
3zqtTESAndrogen receptor/0.442
4elg52JDihydrofolate reductase/0.442
4g1qT27Gag-Pol polyprotein2.7.7.490.442
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.442
4o7lADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.442
1byeATAGlutathione S-transferase 12.5.1.180.441
1c1bGCAGag-Pol polyprotein2.7.7.490.441
1ie4T44Transthyretin/0.441
1jlaTNKGag-Pol polyprotein2.7.7.490.441
1lhvNOGSex hormone-binding globulin/0.441
1u3s797Estrogen receptor beta/0.441
1uy7PU4Heat shock protein HSP 90-alpha/0.441
1xlsREARetinoic acid receptor RXR-alpha/0.441
1yetGDMHeat shock protein HSP 90-alpha/0.441
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.441
2ittAEEEpidermal growth factor receptor2.7.10.10.441
2q7gCCLPyrrolysine--tRNA ligase/0.441
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.441
2y37A54Nitric oxide synthase, inducible1.14.13.390.441
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
3w0gW07Vitamin D3 receptor/0.441
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
4a9e3PFBromodomain-containing protein 2/0.441
4a9hTVPBromodomain-containing protein 2/0.441
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4ejgNCTCytochrome P450 2A131.14.14.10.441
4g2fC07Ephrin type-A receptor 32.7.10.10.441
4hy6FJ1Heat shock protein HSP 90-alpha/0.441
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4nmbFADBifunctional protein PutA/0.441
4nyeADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.441
1cd2FOLDihydrofolate reductase1.5.1.30.440
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1iwiCAMCamphor 5-monooxygenase1.14.15.10.440
1lcoPPYCytochrome b2, mitochondrial1.1.2.30.440
1n4hREANuclear receptor ROR-beta/0.440
1nooCAHCamphor 5-monooxygenase1.14.15.10.440
1o5rFR9Adenosine deaminase3.5.4.40.440
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.440
2eq7NADDihydrolipoyl dehydrogenase/0.440
2fziDH3Dihydrofolate reductase1.5.1.30.440
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2piuDHTAndrogen receptor/0.440
2pmnK51Protein kinase 7/0.440
2xvv9DNSerum albumin/0.440
2ylpTESAndrogen receptor/0.440
3cgeCOACoenzyme A disulfide reductase/0.440
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3ezpB3NHistone deacetylase 83.5.1.980.440
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.440
3hz137DHeat shock protein HSP 90-alpha/0.440
3jzfJZKBiotin carboxylase6.3.4.140.440
3kenZZDKinesin-like protein KIF11/0.440
3s79ASDAromatase1.14.14.140.440
3t3r9PLCytochrome P450 2A61.14.130.440
3vi7CBDHematopoietic prostaglandin D synthase/0.440
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.440
3w32W32Epidermal growth factor receptor2.7.10.10.440
3wrhCAMCamphor 5-monooxygenase1.14.15.10.440
4e5yNDPGDP-L-fucose synthase1.1.1.2710.440
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4i8vBHFCytochrome P450 1A11.14.14.10.440
4jx1CAMCamphor 5-monooxygenase1.14.15.10.440
4l4cCAMCamphor 5-monooxygenase1.14.15.10.440
4lxhC1EAlpha/beta hydrolase fold/0.440
4nh82LCHeat shock protein HSP 90-alpha/0.440
4qzuRTLRetinol-binding protein 2/0.440
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.440
5kgpACOPredicted acetyltransferase/0.440