sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ro8 | C5P | Alpha-2,3-/2,8-sialyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ro8 | C5P | Alpha-2,3-/2,8-sialyltransferase | / | 1.000 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.506 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.505 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.503 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.499 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.492 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.490 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.489 | |
| 3u9e | COA | Lmo1369 protein | / | 0.488 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.488 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.487 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.486 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.483 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.483 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.483 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.482 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.481 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.481 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.481 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.480 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.479 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.479 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.479 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.478 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.478 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.478 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.477 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.477 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.476 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.476 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.476 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.476 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.475 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.475 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.475 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.474 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.474 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.473 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.473 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.473 | |
| 1n75 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.472 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.472 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.472 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.472 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.472 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.472 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.472 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.471 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.470 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.470 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.470 | |
| 1c7o | PPG | Hemolysin | / | 0.469 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.469 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.469 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.469 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.468 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.467 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.467 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.467 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.467 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.466 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.466 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.466 | |
| 3v2u | ATP | Protein GAL3 | / | 0.466 | |
| 1p3d | UMA | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.465 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.465 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.465 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.465 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.465 | |
| 4jic | FMN | GTN Reductase | / | 0.465 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.465 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.464 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.464 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.464 | |
| 3zxi | TYA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.464 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.464 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.463 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.463 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.463 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.462 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.462 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.461 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.461 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.461 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.461 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.461 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.460 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.460 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.460 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.460 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.460 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.459 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.459 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.458 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.458 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.458 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.458 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.457 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.457 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.457 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.457 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.457 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.457 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.457 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.456 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.456 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.456 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.456 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.456 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.456 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.456 | |
| 3gpc | COA | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.456 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.456 | |
| 3x2e | NAI | Adenosylhomocysteinase | / | 0.456 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.456 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.455 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.455 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.455 | |
| 3wag | TYD | Glycosyltransferase | / | 0.455 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.455 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.455 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.454 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.454 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.454 | |
| 5ftf | ADP | TPR domain protein | / | 0.454 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.453 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.453 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.452 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.452 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.452 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.452 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.452 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.452 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.452 | |
| 3eku | CY9 | Actin-5C | / | 0.452 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.452 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.452 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.452 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.451 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.451 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2x93 | X93 | Angiotensin-converting enzyme | 3.4.15.1 | 0.451 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.451 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.451 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.451 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.451 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.451 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.451 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.450 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.450 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.450 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.450 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.450 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.450 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.450 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.450 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.450 | |
| 4nv1 | TYD | Formyl transferase | / | 0.450 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.450 | |
| 5dp2 | NAP | CurF | / | 0.450 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.449 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.449 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.449 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.449 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.449 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.449 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.449 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4lut | DCS | Alanine racemase | / | 0.449 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.449 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.448 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.448 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.448 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.448 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.448 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.448 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.448 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.448 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.447 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.447 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.447 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.447 | |
| 3a3g | DLZ | Lumazine protein | / | 0.447 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3fce | ATP | D-alanine--poly(phosphoribitol) ligase subunit 1 | / | 0.447 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.447 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.447 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.447 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.446 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.446 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.446 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.446 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.446 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.446 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.446 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.446 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 4xq6 | FMN | Dihydroorotate dehydrogenase (quinone) | / | 0.446 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.445 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.445 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.445 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.445 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.445 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4l82 | FMN | Uncharacterized protein | / | 0.445 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.445 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.444 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.444 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.444 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.444 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.444 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.444 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.444 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.444 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.444 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.444 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.444 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.444 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.444 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.443 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.443 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.443 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.443 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.443 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.443 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.442 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.442 | |
| 3r96 | ACO | MccE protein | / | 0.442 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.442 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.442 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.442 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.441 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.441 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.441 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.441 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.441 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.441 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.441 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.441 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.441 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.441 | |
| 4dja | FAD | (6-4) photolyase | / | 0.441 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.441 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.440 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.440 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.440 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.440 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.440 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.440 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.440 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.440 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.440 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.440 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.440 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.440 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4gsu | DWZ | L,D-transpeptidase 2 | 2.3.2 | 0.440 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.440 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 |