sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mgd | ACO | Predicted acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3mgd | ACO | Predicted acetyltransferase | / | 1.000 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.518 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.493 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.492 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.491 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.487 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.486 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.484 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.483 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.483 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.482 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.482 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.482 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.481 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.481 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.480 | |
| 4l4x | NDP | AmphI | / | 0.480 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.479 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.479 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.478 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.477 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.477 | |
| 4qq3 | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.475 | |
| 2ar8 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.474 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.474 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.473 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.471 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.471 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.470 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.469 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.468 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.468 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.468 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.467 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.466 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.466 | |
| 1flm | FMN | FMN-binding protein | / | 0.465 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.465 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.465 | |
| 3zon | IK1 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.465 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.465 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.465 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.465 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.465 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.464 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.464 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.464 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.464 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.464 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.463 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.463 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.463 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.463 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.463 | |
| 4hxy | NDP | Plm1 | / | 0.463 | |
| 5dp2 | NAP | CurF | / | 0.463 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.462 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.462 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.462 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.462 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.461 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.461 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.460 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.460 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.460 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.460 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.460 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.459 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.459 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.457 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.457 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.457 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.457 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3mje | NDP | AmphB | / | 0.457 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4eet | FMN | Phototropin-2 | 2.7.11.1 | 0.457 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.457 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.456 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.456 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.456 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.456 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.456 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.456 | |
| 4i02 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.456 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.456 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.455 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.455 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.455 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.455 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.454 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.454 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.454 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.454 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.454 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.454 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.454 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 2qqf | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.453 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.453 | |
| 3uqd | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.453 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.453 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.453 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.452 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.452 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.452 | |
| 3cr3 | ADP | PTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.452 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.452 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.452 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.452 | |
| 4feh | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.452 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.452 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.452 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.451 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1osv | CHC | Bile acid receptor | / | 0.451 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.451 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.451 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.451 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.451 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.451 | |
| 1nf7 | RVP | Inosine-5'-monophosphate dehydrogenase 2 | / | 0.450 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.450 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.450 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.450 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.450 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.450 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.450 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.450 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.450 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.450 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.449 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.449 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.449 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.449 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.449 | |
| 4b13 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.449 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.449 | |
| 4zrn | UPG | UDP-glucose 4-epimerase, putative | / | 0.449 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.448 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.448 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.448 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.448 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.448 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.448 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.448 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.448 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.448 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.448 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.448 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.448 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.448 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.448 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.448 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.448 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.448 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.447 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.447 | |
| 2e16 | SAH | Diphthine synthase | / | 0.447 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.447 | |
| 4iah | 1DX | Alr2278 protein | / | 0.447 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.447 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.447 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.447 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.447 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.447 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.446 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.446 | |
| 1nq5 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.446 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.446 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 2w6n | OA2 | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.446 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.446 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.446 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.446 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4e2d | FMN | Dehydrogenase | / | 0.446 | |
| 4tlz | NAP | KtzI | / | 0.446 | |
| 1gqt | ACP | Ribokinase | / | 0.445 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.445 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.445 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.445 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.445 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.445 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.445 | |
| 1iy8 | NAD | Levodione reductase | / | 0.444 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.444 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.444 | |
| 3ac1 | KZI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.444 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.444 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.444 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.444 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.444 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.444 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.444 | |
| 4px9 | ADP | ATP-dependent RNA helicase DDX3X | 3.6.4.13 | 0.444 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.444 | |
| 1efp | FAD | Electron transfer flavoprotein subunit alpha | / | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1llq | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.443 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.443 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.443 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.443 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.443 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.443 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.443 | |
| 3f8k | COA | Uncharacterized protein | / | 0.443 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.443 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4l8u | 9AZ | Serum albumin | / | 0.443 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.442 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.442 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.442 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.442 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.442 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.442 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.442 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.442 | |
| 3gvi | ADP | Malate dehydrogenase | / | 0.442 | |
| 3v2u | ATP | Protein GAL3 | / | 0.442 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 4h4w | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.442 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.442 | |
| 4ros | APR | Malate dehydrogenase | / | 0.442 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.441 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3ict | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.441 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.441 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.441 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.441 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.441 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3w0p | ADP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.441 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.441 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.441 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.441 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.441 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 1fml | RTL | Retinol dehydratase | / | 0.440 | |
| 1g2v | TTP | Glucose-1-phosphate thymidylyltransferase | / | 0.440 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.440 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.440 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.440 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2y3s | TIR | TamL | / | 0.440 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.440 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.440 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.440 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.440 | |
| 3icr | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.440 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.440 | |
| 4bmo | FMN | Protein NrdI | / | 0.440 | |
| 4el5 | D1M | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.440 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.440 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.440 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.440 |