sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.740 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.738 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.577 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.574 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.557 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.545 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.541 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.540 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.539 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.539 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.536 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.531 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.530 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.530 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.530 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.528 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.528 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.514 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.509 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.506 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.504 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.503 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.502 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.499 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.496 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.495 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.494 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.491 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.491 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.487 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.487 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.487 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.486 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.486 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.485 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.485 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.484 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.484 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.484 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.483 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.483 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.483 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.482 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.482 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.482 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.481 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.481 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.481 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.480 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.480 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.479 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.478 | |
| 1swt | BTN | Streptavidin | / | 0.478 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.478 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.477 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.476 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.476 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.475 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.475 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.475 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.475 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.474 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.473 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.473 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.471 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.471 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.471 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.470 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.470 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.470 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.470 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.469 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.469 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.469 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.468 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.468 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.468 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.467 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.467 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.467 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.467 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.467 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.466 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.466 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.466 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.466 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.466 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.466 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.466 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.466 | |
| 4iae | 1DX | Alr2278 protein | / | 0.466 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.466 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.465 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.465 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.465 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.465 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.464 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.464 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.463 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.463 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.462 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.462 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.462 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.461 | |
| 1i9h | BNI | Streptavidin | / | 0.461 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.461 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.461 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.461 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.461 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.461 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.461 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.461 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.460 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.460 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.460 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.460 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.460 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.460 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.459 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.458 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.458 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.458 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.458 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.457 | |
| 2po3 | T4K | 4-dehydrase | / | 0.457 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.457 | |
| 2rte | BTN | Streptavidin | / | 0.457 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.457 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.457 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.457 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.456 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.456 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.456 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.456 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.456 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.456 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.456 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.456 | |
| 4h6p | FMN | Chromate reductase | / | 0.456 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.456 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.456 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.456 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.455 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.455 | |
| 2rtd | BTN | Streptavidin | / | 0.455 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.455 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.455 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.455 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.455 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.455 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.455 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.455 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.455 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.454 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.454 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.454 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.454 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.454 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.453 | |
| 1sre | HAB | Streptavidin | / | 0.453 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.453 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.453 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.453 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.453 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.453 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.453 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.453 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.453 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.453 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.453 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.452 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.452 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.452 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.452 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.452 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.452 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.452 | |
| 4iah | 1DX | Alr2278 protein | / | 0.452 | |
| 5dp2 | NAP | CurF | / | 0.452 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.451 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.451 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.451 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.451 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.451 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.451 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.450 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.450 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.450 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.450 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.450 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.450 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.450 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.450 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.450 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.449 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.449 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.449 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.449 | |
| 3t3i | GPW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.449 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2c4i | BTN | Avidin | / | 0.448 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.448 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.448 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.448 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.447 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.447 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.447 | |
| 1zdw | FLV | Prenyltransferase | / | 0.447 | |
| 2a5c | 8DA | Avidin | / | 0.447 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.447 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.447 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.447 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.447 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.447 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.447 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.447 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.447 | |
| 1c7o | PPG | Hemolysin | / | 0.446 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.446 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.446 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.446 | |
| 2rto | IMI | Streptavidin | / | 0.446 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.446 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.446 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.445 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.445 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.445 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2emr | SAH | Diphthine synthase | / | 0.445 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.445 | |
| 3hnz | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.445 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.445 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.445 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.445 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.445 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1kwc | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.444 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.444 | |
| 1til | ATP | Anti-sigma F factor | / | 0.444 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.444 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.444 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.444 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.443 | |
| 1stp | BTN | Streptavidin | / | 0.443 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.443 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.443 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.443 | |
| 2izl | IMI | Streptavidin | / | 0.443 | |
| 2rtf | BTN | Streptavidin | / | 0.443 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.443 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.443 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.443 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.443 | |
| 3ry2 | BTN | Streptavidin | / | 0.443 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.443 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 5jqh | CAU | Beta-2 adrenergic receptor | / | 0.443 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2eit | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.442 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.442 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.442 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4e2z | JHZ | Methyltransferase | / | 0.442 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.442 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.441 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.441 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.441 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.441 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.441 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.441 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.441 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.441 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.441 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.441 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.441 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.441 | |
| 1avd | BTN | Avidin | / | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.440 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.440 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.440 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.440 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 2glr | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.440 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3f90 | FMN | Flavodoxin | / | 0.440 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.440 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.440 | |
| 4jic | FMN | GTN Reductase | / | 0.440 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 |