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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ioaADPBifunctional glutathionylspermidine synthetase/amidase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2ioaADPBifunctional glutathionylspermidine synthetase/amidase/1.000
2io8ADPBifunctional glutathionylspermidine synthetase/amidase/0.565
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.535
1x8b824Wee1-like protein kinase2.7.10.20.522
2o7pNAPRiboflavin biosynthesis protein RibD/0.521
5iqgGDPBifunctional AAC/APH2.3.10.512
5iqaGNPBifunctional AAC/APH2.3.10.505
1id0ANPSensor protein PhoQ2.7.13.30.503
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.501
1yqj6NPMitogen-activated protein kinase 14/0.498
1i2cUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.497
4xzjNADPutative NAD(+)--arginine ADP-ribosyltransferase Vis2.4.2.310.496
2xrlDXTTetracycline repressor protein class D/0.495
3bi6396Wee1-like protein kinase2.7.10.20.495
2cahNDPCatalase1.11.1.60.494
2in6839Wee1-like protein kinase2.7.10.20.494
5iqbGNPBifunctional AAC/APH2.3.10.494
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.493
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.492
5bylGCPBifunctional AAC/APH2.3.10.492
1hfqMOTDihydrofolate reductase1.5.1.30.491
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/0.491
5iqeGNPBifunctional AAC/APH2.3.10.491
1goxFMNPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.490
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.490
5cvhADPCasein kinase II subunit alpha2.7.11.10.490
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.489
5iqiGNPBifunctional AAC/APH2.3.10.487
3nszANPCasein kinase II subunit alpha2.7.11.10.486
4yekTHMThymidine phosphorylase/0.486
4eixNIMPhospholipase A2 VRV-PL-VIIIa/0.484
2zdt46CMitogen-activated protein kinase 102.7.11.240.483
1i2bNADUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.482
1ne4RP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.482
2j9gADPBiotin carboxylase6.3.4.140.482
2z2w770Wee1-like protein kinase2.7.10.20.482
4f1oACPProbable serine/threonine-protein kinase roco42.7.11.10.481
2bakAQZMitogen-activated protein kinase 14/0.480
2e20B4PPropionate kinase/0.480
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.480
3d5wADPSerine/threonine-protein kinase PLK/0.480
4a9yAQZMitogen-activated protein kinase 14/0.480
1y5xE89Queuine tRNA-ribosyltransferase2.4.2.290.479
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.479
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.479
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.479
2pulACPMethylthioribose kinase2.7.1.1000.478
4d7mTDCTetracycline repressor protein class D/0.478
5iqdGNPBifunctional AAC/APH2.3.10.478
1iahADPTransient receptor potential cation channel subfamily M member 72.7.11.10.476
1r8qAFBCytohesin-2/0.476
1r8qAFBADP-ribosylation factor 1/0.476
3ae4FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.476
3hziATPSerine/threonine-protein kinase toxin HipA/0.476
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.476
4autFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.476
4y6uUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.475
2j9lATPH(+)/Cl(-) exchange transporter 5/0.474
2pupADPMethylthioribose kinase2.7.1.1000.474
2w5aADPSerine/threonine-protein kinase Nek22.7.11.10.474
1ftlDNQGlutamate receptor 2/0.473
2glxNDP1,5-anhydro-D-fructose reductase/0.473
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.473
3up0D7SaceDAF-12/0.473
4bixADPSensor histidine kinase CpxA/0.472
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.472
4oa9ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.471
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.470
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.470
2o7oDXTTetracycline repressor protein class D/0.469
4e37NDPCatalase1.11.1.60.469
4lrjANPUncharacterized protein/0.469
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.468
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.468
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.468
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.468
2geuCOKPantothenate kinase2.7.1.330.467
2vkdUPGCytotoxin L/0.467
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.467
2a5kAZPReplicase polyprotein 1ab3.4.220.466
3kzoAN0N-acetylornithine carbamoyltransferase2.1.3.90.466
4jr7GNPCasein kinase II subunit alpha2.7.11.10.466
4y12AGSSerine/threonine-protein kinase PknG2.7.11.10.466
1h51FMNPentaerythritol tetranitrate reductase/0.465
3datMTXDihydrofolate reductase/0.465
3q60ATPRhoptry protein 5B/0.465
3v0o4GWHisto-blood group ABO system transferase/0.465
4k5o1OTM1 family aminopeptidase3.4.110.465
5fkmTDCTetracycline repressor protein class D/0.465
1vyrFMNPentaerythritol tetranitrate reductase/0.464
1zydATPeIF-2-alpha kinase GCN2/0.464
3fhxPXLPyridoxal kinase2.7.1.350.464
3l3rOAGDihydrofolate reductase1.5.1.30.464
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.464
3zcxNADGlyceraldehyde-3-phosphate dehydrogenase/0.464
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.464
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.464
4jlm1NNDeoxycytidine kinase2.7.1.740.464
4k8aK8AFocal adhesion kinase 12.7.10.20.464
1i44ACPInsulin receptor2.7.10.10.463
1ne6SP1cAMP-dependent protein kinase type I-alpha regulatory subunit/0.463
1u1cBAUUridine phosphorylase2.4.2.30.463
1xxjUNCUricase1.7.3.30.463
3fhxPLPPyridoxal kinase2.7.1.350.463
1xbtTTPThymidine kinase, cytosolic2.7.1.210.462
1z6lFADPolyamine oxidase FMS1/0.462
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.462
3epsATPIsocitrate dehydrogenase kinase/phosphatase/0.462
4feu537Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.462
4foxUMPThymidylate synthase ThyA/0.462
4xe606UDihydrofolate reductase1.5.1.30.462
5iqhGNPBifunctional AAC/APH2.3.10.462
1vbiNADMalate/L-lactate dehydrogenase family protein/0.461
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
2vbpVB1Isopenicillin N synthase1.21.3.10.461
2vmyFFOSerine hydroxymethyltransferase/0.461
3cgyRDCVirulence sensor histidine kinase PhoQ2.7.13.30.461
4hj4FMNLOV protein/0.461
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.460
2owb626Serine/threonine-protein kinase PLK12.7.11.210.460
4bqyFNTEgl nine homolog 1/0.460
4fvqATPTyrosine-protein kinase JAK2/0.460
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.460
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.459
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.459
2cjfRP43-dehydroquinate dehydratase4.2.1.100.459
2e1zB4PPropionate kinase/0.459
2wo7ASVIsopenicillin N synthase1.21.3.10.459
2y6fM9FIsopenicillin N synthase1.21.3.10.459
2zb45OPProstaglandin reductase 21.3.1.480.459
3af3GCPPantothenate kinase2.7.1.330.459
3cqeP91Wee1-like protein kinase2.7.10.20.459
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.459
3p8iFMNPentaerythritol tetranitrate reductase/0.459
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.459
4bqwQNMEgl nine homolog 1/0.459
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.459
4o7uTHFThymidylate synthase/0.459
5fkoTDCTetracycline repressor protein class D/0.459
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.458
1b39ATPCyclin-dependent kinase 22.7.11.220.458
1orkATCTetracycline repressor protein class D/0.458
2hq9FADMll6688 protein/0.458
2puiADPMethylthioribose kinase2.7.1.1000.458
3dntATPSerine/threonine-protein kinase toxin HipA/0.458
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.458
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.458
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.457
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.457
3bx5304Mitogen-activated protein kinase 14/0.457
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
1dliUDXUDP-glucose 6-dehydrogenase/0.456
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.456
2ozoANPTyrosine-protein kinase ZAP-702.7.10.20.456
3g1oRF1HTH-type transcriptional regulator EthR/0.456
3p97SAMGenome polyprotein2.1.1.560.456
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.456
4bmpFMNProtein NrdI/0.456
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.456
4twnB96Ephrin type-A receptor 32.7.10.10.456
4xbfFADLysine-specific histone demethylase 1A10.456
1e94ANPATP-dependent protease ATPase subunit HslU/0.455
1h36R88Squalene--hopene cyclase4.2.1.1290.455
1i5aACPChemotaxis protein CheA2.7.13.30.455
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.455
1lhwESMSex hormone-binding globulin/0.455
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.455
2bufADPAcetylglutamate kinase/0.455
3a7jADPSerine/threonine-protein kinase 242.7.11.10.455
3pxkPXKFocal adhesion kinase 12.7.10.20.455
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.455
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.455
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.454
1txtCAAHMG-CoA synthase/0.454
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3nguADPNucleoside diphosphate kinase/0.454
3nksACJProtoporphyrinogen oxidase1.3.3.40.454
3rv3ADPBiotin carboxylase6.3.4.140.454
4cvbPQQAlcohol dehydrogenase/0.454
4fxfATPPyruvate kinase PKM2.7.1.400.454
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.454
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.454
5e92ANPTGF-beta receptor type-22.7.11.300.454
5fm6ADPRuvB-like helicase/0.454
1cdkANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
1fq1ATPCyclin-dependent kinase 22.7.11.220.453
1ol5ADPAurora kinase A2.7.11.10.453
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.453
1udaUFGUDP-glucose 4-epimerase5.1.3.20.453
2bfmTOPPteridine reductase 11.5.1.330.453
2rhrEMOPutative ketoacyl reductase1.3.10.453
2vqdAP2Biotin carboxylase6.3.4.140.453
3a783EVVitamin D3 receptor/0.453
3rl35GPMetallophosphoesterase MPPED23.10.453
3tptADPSerine/threonine-protein kinase toxin HipA/0.453
4bb2STRCorticosteroid-binding globulin/0.453
4cnzADPNitrogen regulatory protein P-II 1/0.453
1yp3ATPGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.452
2w6pOA4Biotin carboxylase6.3.4.140.452
2x7jTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.452
2zzaFOLDihydrofolate reductase/0.452
3biz61EWee1-like protein kinase2.7.10.20.452
3c4wATPRhodopsin kinase/0.452
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.452
3p8jFMNPentaerythritol tetranitrate reductase/0.452
3qge26FGenome polyprotein2.7.7.480.452
1l8qADPChromosomal replication initiator protein DnaA/0.451
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2kceD16Thymidylate synthase/0.451
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.451
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.451
2w3mFOLDihydrofolate reductase1.5.1.30.451
2zsiGA4Gibberellin receptor GID1A30.451
3ingNDPHomoserine dehydrogenase related protein/0.451
3k4551PDihydrofolate reductase1.5.1.30.451
3llaACPMyosin heavy chain kinase A2.7.11.70.451
4boyNADGlyceraldehyde-3-phosphate dehydrogenase/0.451
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.451
4nfsNAJAlcohol dehydrogenase E chain1.1.1.10.451
5cvcPLPSerine racemase/0.451
5dtoSAHGenome polyprotein/0.451
5jjrSAHGenome polyprotein/0.451
1icqFMN12-oxophytodienoate reductase 11.3.1.420.450
1mf0GDPAdenylosuccinate synthetase isozyme 1/0.450
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.450
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.450
2hog710Serine/threonine-protein kinase Chk12.7.11.10.450
2z4sADPChromosomal replication initiator protein DnaA/0.450
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.450
3e8xNAPBH1520 protein/0.450
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.450
3v0m5GWHisto-blood group ABO system transferase/0.450
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.450
4fr10V2Queuine tRNA-ribosyltransferase2.4.2.290.450
5ab7MLCNonspecific lipid-transfer protein, putative/0.450
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1fw0KAIGlutamate receptor 2/0.449
2qqfA1RNAD-dependent protein deacetylase HST23.5.10.449
2xpvMIYTetracycline repressor protein class D/0.449
2xpwOTCTetracycline repressor protein class D/0.449
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.449
2zseACPPantothenate kinase2.7.1.330.449
3ia4MTXDihydrofolate reductase/0.449
3iw4LW4Protein kinase C alpha type2.7.11.130.449
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.449
4b68NAPL-ornithine N(5)-monooxygenase/0.449
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.449
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.449
4gdpFADPolyamine oxidase FMS1/0.449
4hj6FMNLOV protein/0.449
4qmlANPSerine/threonine-protein kinase 242.7.11.10.449
4r38RBFBlue-light-activated histidine kinase 22.7.13.30.449
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.449
1cm8ANPMitogen-activated protein kinase 12/0.448
1crbRTLRetinol-binding protein 1/0.448
1lp4ANPCasein kinase II subunit alpha2.7.11.10.448
1t86CAMCamphor 5-monooxygenase1.14.15.10.448
2fzjDH3Dihydrofolate reductase1.5.1.30.448
2pdtFADVivid PAS protein VVD/0.448
3ormAGSSerine/threonine protein kinase/0.448
4f0fACPProbable serine/threonine-protein kinase roco42.7.11.10.448
4oauADP2-5A-dependent ribonuclease3.1.260.448
4xybNDPFormate dehydrogenase/0.448
5e9eANPMyosin heavy chain kinase A2.7.11.70.448
3qakUKAAdenosine receptor A2a/0.448
1bwkFMNNADPH dehydrogenase 11.6.99.10.447
1e92HBIPteridine reductase 11.5.1.330.447
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.447
1oc1ASVIsopenicillin N synthase1.21.3.10.447
1zzlTZYMitogen-activated protein kinase 14/0.447
2z1xPRFQueuine tRNA-ribosyltransferase2.4.2.290.447
2zjwREFCasein kinase II subunit alpha2.7.11.10.447
3lmhADPMyosin heavy chain kinase A2.7.11.70.447
3o9pMHIPeriplasmic murein peptide-binding protein/0.447
3pn1IVHDNA ligase/0.447
4deg0JJHepatocyte growth factor receptor2.7.10.10.447
4f9aADPCell division cycle 7-related protein kinase2.7.11.10.447
4s33ANPMitogen-activated protein kinase 12.7.11.240.447
4tx9AMZPhosphoribosyl isomerase A/0.447
1csnATPCasein kinase I homolog 12.7.11.10.446
1lb9DNQGlutamate receptor 2/0.446
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.446
1srfMTBStreptavidin/0.446
1towCRZFatty acid-binding protein, adipocyte/0.446
1u54ACPActivated CDC42 kinase 1/0.446
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.446
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.446
2uzhCDP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.446
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.446
2ylsFADPhenylacetone monooxygenase1.14.13.920.446
3l05SN0N-acetylornithine carbamoyltransferase2.1.3.90.446
3r8uZ31Cyclin-dependent kinase 22.7.11.220.446
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.446
1adfTADAlcohol dehydrogenase E chain1.1.1.10.445
1opbRETRetinol-binding protein 2/0.445
1p4aPCPPur operon repressor/0.445
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1u1f183Uridine phosphorylase2.4.2.30.445
2c29NAPDihydroflavonol 4-reductase/0.445
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.445
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.445
3cr0809Wee1-like protein kinase2.7.10.20.445
3p67FMNPentaerythritol tetranitrate reductase/0.445
3sa16DRDihydrofolate reductase/0.445
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.445
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.445
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.445
4qlyFMNEnone reductase CLA-ER/0.445
4uxxACPDiacylglycerol kinase2.7.1.1070.445
4y95746Tyrosine-protein kinase/0.445
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.445
5hbsRTLRetinol-binding protein 1/0.445
5iotUMPFlavin-dependent thymidylate synthase2.1.1.1480.445
1q45FMN12-oxophytodienoate reductase 31.3.1.420.444
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.444
2a9z26AAdenosine kinase2.7.1.200.444
2bgiFADNADPH:ferredoxin reductase/0.444
2iypA2P6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.444
2qk8MTXDihydrofolate reductase/0.444
2rirNAPDipicolinate synthase subunit A/0.444
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4hneADPPhosphatidylinositol 4-kinase type 2-alpha/0.444
4rnxFMNNADPH dehydrogenase 11.6.99.10.444
5dt3ATPAurora kinase A2.7.11.10.444
5kf9COAPredicted acetyltransferase/0.444
1dgbNDPCatalase1.11.1.60.443
1eqbFFOSerine hydroxymethyltransferase2.1.2.10.443
1h63FMNPentaerythritol tetranitrate reductase/0.443
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.443
2c97JCL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2tsrUMPThymidylate synthase2.1.1.450.443
2vf7ADPUvrABC system protein A/0.443
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.443
2z9dFMNFMN-dependent NADH-azoreductase/0.443
3d74NBBPheromone-binding protein ASP1/0.443
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.443
3is2FADVivid PAS protein VVD/0.443
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.443
3otwCOAPhosphopantetheine adenylyltransferase/0.443
3qeoLLTDeoxycytidine kinase2.7.1.740.443
3sh25DRDihydrofolate reductase1.5.1.30.443
4auxXTCTetracycline repressor protein class D/0.443
4dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.443
4eevL1XHepatocyte growth factor receptor2.7.10.10.443
4f3gKAIGlutamate receptor 3/0.443
4knzCB3Thymidylate synthase/0.443
4n3l2FNProthrombin3.4.21.50.443
4o1pANPRibonuclease L/0.443
4u0oMTALipoyl synthase 2/0.443
5ab6CAANonspecific lipid-transfer protein, putative/0.443
1clqGDPDNA-directed DNA polymerase/0.442
1nqxRLP6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.442
2ea1GPGRibonuclease I3.1.27.60.442
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.442
2ftoTMPThymidylate synthase/0.442
2pl0STITyrosine-protein kinase Lck2.7.10.20.442
2q3fGNPRas-related GTP-binding protein D/0.442
3h0bB35Beta-secretase 13.4.23.460.442
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.442
3sl2ATPSensor histidine kinase WalK/0.442
3wv8ATPHmd co-occurring protein HcgE/0.442
4gt8ADPSensor protein VraS2.7.13.30.442
4ix5ANPUncharacterized protein/0.442
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.442
4krcAGSCyclin-dependent protein kinase PHO852.7.11.220.442
4ramPNMMetallo-beta-lactamase type 2/0.442
4y6nUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.442
4zm3PLPAminotransferase/0.442
5je2SAHMethyl transferase/0.442
1gq2NAPNADP-dependent malic enzyme1.1.1.400.441
1mqbANPEphrin type-A receptor 22.7.10.10.441
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.441
1nhhANPDNA mismatch repair protein MutL/0.441
1o9bNAIQuinate/shikimate dehydrogenase/0.441
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.441
2ihvTPPN(2)-(2-carboxyethyl)arginine synthase/0.441
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.441
2v1aFMNNPH1-1/0.441
3bgxMEFThymidylate synthase/0.441
3dogNNNCyclin-dependent kinase 22.7.11.220.441
3fmmXI2Mitogen-activated protein kinase 14/0.441
3gcq1BUMitogen-activated protein kinase 14/0.441
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.441
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.441
3x2vATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4dhyS41Glucokinase2.7.1.20.441
4gncASORegucalcin3.1.1.170.441
4mv4ACPBiotin carboxylase6.3.4.140.441
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.441
3emlZMAAdenosine receptor A2a/0.441
1mvsDTMDihydrofolate reductase1.5.1.30.440
1ohjCOPDihydrofolate reductase1.5.1.30.440
1rd4L08Integrin alpha-L/0.440
2hf8GSPProbable hydrogenase nickel incorporation protein HypB/0.440
2vdyHCYCorticosteroid-binding globulin/0.440
2vkvTDCTetracycline repressor protein class D/0.440
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.440
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3ed1GA3Gibberellin receptor GID1/0.440
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.440
3i8aN22Dihydrofolate reductase1.5.1.30.440
4f4qFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.440
4l9q9TPSerum albumin/0.440
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.440
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
5dt9NADErythronate-4-phosphate dehydrogenase/0.440
5jtbZMAAdenosine receptor A2a/0.440