sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 1.000 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.767 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.723 | |
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.678 | |
| 2fke | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.672 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.658 | |
| 1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.649 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.635 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.631 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.623 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.620 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.620 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.620 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.618 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.618 | |
| 1c9h | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1B | 5.2.1.8 | 0.615 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.615 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.608 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.600 | |
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.599 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.598 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.594 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.594 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.593 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.588 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.583 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.583 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.581 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.577 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.575 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.573 | |
| 4drp | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.571 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.570 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.568 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.563 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.563 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.560 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.517 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.497 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.496 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.491 | |
| 4o7g | ASC | Probable transmembrane ascorbate ferrireductase 2 | 1.16.5.1 | 0.490 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.489 | |
| 1lke | DOG | Bilin-binding protein | / | 0.489 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.487 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.487 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.487 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.486 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.485 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.485 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.484 | |
| 3i0o | SMI | Spectinomycin phosphotransferase | / | 0.484 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.483 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.483 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.483 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.482 | |
| 3v0m | 5GW | Histo-blood group ABO system transferase | / | 0.482 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.481 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.481 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.481 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.480 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.480 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.480 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.480 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.478 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.478 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.478 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.478 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.477 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.476 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 1el4 | CTZ | Obelin | / | 0.475 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.475 | |
| 3e6e | DCS | Alanine racemase | / | 0.475 | |
| 1lbm | 137 | N-(5'-phosphoribosyl)anthranilate isomerase | 5.3.1.24 | 0.474 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.474 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.474 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.474 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.473 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.473 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.472 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.472 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.472 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.471 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.471 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.470 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.470 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.469 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.468 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.468 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.468 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.468 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.468 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.468 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.467 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.466 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.466 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.466 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.466 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.466 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.466 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.466 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.465 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.464 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.464 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.464 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 4iif | CTS | Beta-glucosidase 1 | 3.2.1.21 | 0.464 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.464 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.463 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.463 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.463 | |
| 4cb5 | 93G | Polymerase basic protein 2 | / | 0.463 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.463 | |
| 1p4r | 354 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.462 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.462 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.462 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 3sff | 0DI | Histone deacetylase 8 | 3.5.1.98 | 0.462 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.462 | |
| 5dv2 | C5P | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.462 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.461 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.461 | |
| 2nm2 | NEU | Dihydroneopterin aldolase | / | 0.461 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.461 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.461 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.461 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.461 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.460 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.460 | |
| 3g5i | DNB | Pyrimidine-specific ribonucleoside hydrolase RihA | / | 0.460 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.460 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.460 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.460 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.459 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.459 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.459 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.459 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.459 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.459 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.459 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.459 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.459 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.458 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.458 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.458 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.458 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1a80 | NDP | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.457 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.457 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.457 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.457 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.457 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.457 | |
| 4flj | Y08 | Methionine aminopeptidase 1 | / | 0.457 | |
| 1mc0 | PCG | cGMP-dependent 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.456 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.456 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.456 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.456 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.456 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.455 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.455 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.455 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.455 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.455 | |
| 4fll | YZ6 | Methionine aminopeptidase 1 | / | 0.455 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.455 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.455 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.455 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.454 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.454 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.454 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.454 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3ksl | SZH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.454 | |
| 3mey | ATP | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.454 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.454 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.454 | |
| 4h2u | ATP | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.454 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.454 | |
| 1acj | THA | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.453 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.453 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.453 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.453 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.453 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.453 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.453 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.453 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.452 | |
| 2dxf | GNP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.452 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.452 | |
| 3ccb | B2Y | Dipeptidyl peptidase 4 | / | 0.452 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.452 | |
| 4e31 | JHZ | Methyltransferase | / | 0.452 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.452 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.451 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.451 | |
| 1wm1 | PTB | Proline iminopeptidase | 3.4.11.5 | 0.451 | |
| 2gg3 | U13 | Methionine aminopeptidase | / | 0.451 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3ccc | 7AC | Dipeptidyl peptidase 4 | / | 0.451 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.451 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.451 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.451 | |
| 3nt5 | NAI | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.451 | |
| 3qd0 | 3Q4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.451 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.450 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.450 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.450 | |
| 3i97 | 8DR | Neuropilin-1 | / | 0.450 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.450 | |
| 5c8a | 5AD | Probable transcriptional regulator | / | 0.450 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.449 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.449 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.449 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.449 | |
| 3pzc | GAP | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.449 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4rel | KMP | Glycosyltransferase | / | 0.449 | |
| 5ief | NBV | Neutral alpha-glucosidase AB | 3.2.1.84 | 0.449 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.448 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.448 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.448 | |
| 2xjc | 5GP | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.448 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.448 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.448 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.448 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.448 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.447 | |
| 2r4t | ADP | Glycogen synthase | 2.4.1.21 | 0.447 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.447 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.447 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.447 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.447 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.447 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.446 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.446 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.446 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.446 | |
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 | / | 0.446 | |
| 2aj8 | SC3 | Dipeptidyl peptidase 4 | / | 0.446 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.446 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.446 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.446 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.446 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.446 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.446 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4h2w | 5GP | Amino acid--[acyl-carrier-protein] ligase 1 | 6.2.1.n2 | 0.446 | |
| 5c3r | HMU | Thymine dioxygenase | / | 0.446 | |
| 1c7o | PPG | Hemolysin | / | 0.445 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.445 | |
| 2gl0 | ADN | Uncharacterized protein | / | 0.445 | |
| 2h3w | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.445 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.445 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2wea | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.445 | |
| 3arp | DEQ | Chitinase A | / | 0.445 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.445 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.445 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.445 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.445 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.445 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 1cq6 | PY4 | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1dcy | I3N | Phospholipase A2, membrane associated | / | 0.444 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.444 | |
| 2j7d | GI1 | Beta-glucosidase A | 3.2.1.21 | 0.444 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.444 | |
| 2x9g | LYA | Pteridine reductase | / | 0.444 | |
| 3kfl | ME8 | Putative methionyl-tRNA synthetase | / | 0.444 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.444 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.444 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.443 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.443 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.443 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.443 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.443 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.443 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.443 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.443 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.443 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.443 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.443 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.443 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.443 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.443 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.443 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.443 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.442 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.442 | |
| 1n4q | LYS_CYS_VAL_ILE_LEU | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.442 | |
| 1s0j | MUS | Trans-sialidase | / | 0.442 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.442 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.442 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.442 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.442 | |
| 3iwj | NAD | Aminoaldehyde dehydrogenase | / | 0.442 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.442 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.442 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.441 | |
| 1jf0 | CZH | Obelin | / | 0.441 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.441 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.441 | |
| 1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 1qv0 | CZH | Obelin | / | 0.441 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.441 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.441 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.441 | |
| 1xh6 | R94 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.441 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.441 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.441 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.440 | |
| 1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.440 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.440 | |
| 1swg | BTN | Streptavidin | / | 0.440 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 1uhh | CZP | Aequorin-2 | / | 0.440 | |
| 2db3 | ANP | ATP-dependent RNA helicase vasa, isoform A | 3.6.4.13 | 0.440 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.440 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.440 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.440 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3wqt | ANP | Cell division protein FtsA | / | 0.440 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.440 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.440 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.440 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.440 |