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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4fv8E63Mitogen-activated protein kinase 12.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4fv8E63Mitogen-activated protein kinase 12.7.11.241.000
4fv9E71Mitogen-activated protein kinase 12.7.11.240.586
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.551
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.533
4fv6E57Mitogen-activated protein kinase 12.7.11.240.533
3r83Z14Cyclin-dependent kinase 22.7.11.220.529
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.528
2hog710Serine/threonine-protein kinase Chk12.7.11.10.526
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.524
3rm618ZCyclin-dependent kinase 22.7.11.220.523
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.520
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.520
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.520
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.519
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.518
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.518
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.518
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.517
4g6oE28Mitogen-activated protein kinase 12.7.11.240.515
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.513
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.511
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.509
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.509
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.508
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.508
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.508
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.508
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.507
2c4g514Cyclin-dependent kinase 22.7.11.220.506
3zh8C58Protein kinase C iota type2.7.11.130.506
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.504
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.504
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.503
2fvdLIACyclin-dependent kinase 22.7.11.220.503
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.503
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.502
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.502
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.502
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.502
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.501
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.501
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.500
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.500
4h3qANPMitogen-activated protein kinase 12.7.11.240.500
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.499
4h3pANPMitogen-activated protein kinase 12.7.11.240.499
2vu3LZECyclin-dependent kinase 22.7.11.220.498
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.498
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.497
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.497
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.497
3pxkPXKFocal adhesion kinase 12.7.10.20.497
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.497
1e9hINRCyclin-dependent kinase 22.7.11.220.496
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.496
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.496
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.495
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.495
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.495
4qnaX11Serine/threonine-protein kinase 242.7.11.10.495
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.494
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.494
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.494
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.494
2oji33AMitogen-activated protein kinase 12.7.11.240.493
3zep1NXTyrosine-protein kinase JAK32.7.10.20.493
4riyADPEpidermal growth factor receptor2.7.10.10.493
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.492
3i60E86Mitogen-activated protein kinase 12.7.11.240.491
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.491
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.491
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.490
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.490
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.490
1pjkANPCasein kinase II subunit alpha2.7.11.10.489
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.488
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.488
2wipP49Cyclin-dependent kinase 22.7.11.220.488
4fuxE75Mitogen-activated protein kinase 12.7.11.240.488
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.488
3sheI85MAP kinase-activated protein kinase 32.7.11.10.487
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.487
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.487
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.487
2bkzSBCCyclin-dependent kinase 22.7.11.220.486
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.486
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.486
4aguD15Cyclin-dependent kinase-like 1/0.485
4fmqANPMitogen-activated protein kinase 12.7.11.240.485
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.485
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.484
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.484
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.484
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.484
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.484
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.484
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.484
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.483
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.483
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.483
3qrtX14Cyclin-dependent kinase 22.7.11.220.483
3qyw6PBMitogen-activated protein kinase 12.7.11.240.483
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.483
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.483
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.483
4wboANWRhodopsin kinase/0.483
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.482
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.482
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.482
4bcqTJFCyclin-dependent kinase 22.7.11.220.482
4gevCB3Thymidylate synthase/0.482
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.481
2r3gSC9Cyclin-dependent kinase 22.7.11.220.481
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.481
4nifANPMitogen-activated protein kinase 12.7.11.240.481
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.480
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.480
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.480
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.480
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.480
3r9dX6BCyclin-dependent kinase 22.7.11.220.480
3rm719ZCyclin-dependent kinase 22.7.11.220.480
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.480
4bcnT9NCyclin-dependent kinase 22.7.11.220.480
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.480
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.480
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.479
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.479
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
3ddpRC8Cyclin-dependent kinase 22.7.11.220.478
3lfnA27Cyclin-dependent kinase 22.7.11.220.478
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.478
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.478
4fod0UVALK tyrosine kinase receptor2.7.10.10.478
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.477
2r3fSC8Cyclin-dependent kinase 22.7.11.220.477
2x1nX1NCyclin-dependent kinase 22.7.11.220.477
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.477
3w551FMMitogen-activated protein kinase 12.7.11.240.477
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.477
2xp2VGHALK tyrosine kinase receptor2.7.10.10.476
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.476
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.475
2qo9ANPEphrin type-A receptor 32.7.10.10.475
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.475
3qqkX02Cyclin-dependent kinase 22.7.11.220.475
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.475
4fkj11KCyclin-dependent kinase 22.7.11.220.475
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
1ykr628Cyclin-dependent kinase 22.7.11.220.474
2w7xD1ASerine/threonine-protein kinase Chk22.7.11.10.474
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.474
3bqr4RBDeath-associated protein kinase 3/0.474
3teiANPMitogen-activated protein kinase 12.7.11.240.474
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.474
4jq8KJ8Epidermal growth factor receptor2.7.10.10.474
1oiyN41Cyclin-dependent kinase 22.7.11.220.473
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.473
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.472
2xb7GUIALK tyrosine kinase receptor2.7.10.10.472
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.472
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.472
3nup3NUCyclin-dependent kinase 62.7.11.220.472
3qwjX6ACyclin-dependent kinase 22.7.11.220.472
3rkb12ZCyclin-dependent kinase 22.7.11.220.472
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.472
4ccuAWFALK tyrosine kinase receptor2.7.10.10.472
2wtjWTJSerine/threonine-protein kinase Chk22.7.11.10.471
2wxvWXVCyclin-dependent kinase 22.7.11.220.471
3qzhX69Cyclin-dependent kinase 22.7.11.220.471
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.471
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.470
3r1sX73Cyclin-dependent kinase 22.7.11.220.470
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.469
3ogqAB1Pol polyprotein/0.469
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.469
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.469
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.468
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.468
2j0j4STFocal adhesion kinase 12.7.10.20.468
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.468
4fkt48KCyclin-dependent kinase 22.7.11.220.468
4i22IREEpidermal growth factor receptor2.7.10.10.468
1h7wFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.467
1oi9N20Cyclin-dependent kinase 22.7.11.220.467
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.467
2b52D42Cyclin-dependent kinase 22.7.11.220.467
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.467
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.467
3r7uX96Cyclin-dependent kinase 22.7.11.220.467
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.467
3zptM8YGag-Pol polyprotein3.4.23.160.467
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.467
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.467
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.467
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.467
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.466
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.466
2itnANPEpidermal growth factor receptor2.7.10.10.466
2j9mPY8Cyclin-dependent kinase 22.7.11.220.466
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.466
3rpv26ZCyclin-dependent kinase 22.7.11.220.466
3vf80JETyrosine-protein kinase SYK2.7.10.20.466
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.466
4fob0USALK tyrosine kinase receptor2.7.10.10.466
1tvoFRZMitogen-activated protein kinase 12.7.11.240.465
2ituITQEpidermal growth factor receptor2.7.10.10.465
3qx2X63Cyclin-dependent kinase 22.7.11.220.465
3rni21ZCyclin-dependent kinase 22.7.11.220.465
3sqq99ZCyclin-dependent kinase 22.7.11.220.465
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.465
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.465
1ke6LS2Cyclin-dependent kinase 22.7.11.220.464
1oguST8Cyclin-dependent kinase 22.7.11.220.464
1oiuN76Cyclin-dependent kinase 22.7.11.220.464
3biz61EWee1-like protein kinase2.7.10.20.464
3ezvEZVCyclin-dependent kinase 22.7.11.220.464
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.464
3qtrX36Cyclin-dependent kinase 22.7.11.220.464
3u4uLNHCasein kinase II subunit alpha2.7.11.10.464
3umw596Serine/threonine-protein kinase pim-12.7.11.10.464
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.464
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.464
4i231C9Epidermal growth factor receptor2.7.10.10.464
1eh4IC1Casein kinase I homolog 12.7.11.10.463
1unlRRCCyclin-dependent-like kinase 52.7.11.10.463
2bfyH1NAurora kinase B-A2.7.11.10.463
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.463
2wpa889Cyclin-dependent kinase 22.7.11.220.463
3roy22ZCyclin-dependent kinase 22.7.11.220.463
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.463
4ji91M3Tyrosine-protein kinase JAK2/0.463
1gih1PUCyclin-dependent kinase 22.7.11.220.462
1m2rMNYCasein kinase II subunit alpha2.7.11.10.462
2ittAEEEpidermal growth factor receptor2.7.10.10.462
2iw84SPCyclin-dependent kinase 22.7.11.220.462
3gc9B45Mitogen-activated protein kinase 112.7.11.240.462
3r8lZ30Cyclin-dependent kinase 22.7.11.220.462
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
4c62XWWTyrosine-protein kinase JAK2/0.462
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.462
1aq1STUCyclin-dependent kinase 22.7.11.220.461
1fvt106Cyclin-dependent kinase 22.7.11.220.461
1pxmCK5Cyclin-dependent kinase 22.7.11.220.461
2c475IDCasein kinase I isoform gamma-2/0.461
2yn8STUEphrin type-B receptor 42.7.10.10.461
3at4CCKCasein kinase II subunit alpha2.7.11.10.461
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.461
3qxoX65Cyclin-dependent kinase 22.7.11.220.461
3rk507ZCyclin-dependent kinase 22.7.11.220.461
3s2pPMUCyclin-dependent kinase 22.7.11.220.461
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.461
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.461
2c6iDT1Cyclin-dependent kinase 22.7.11.220.460
3ezrEZRCyclin-dependent kinase 22.7.11.220.460
3pj8404Cyclin-dependent kinase 22.7.11.220.460
3rak03ZCyclin-dependent kinase 22.7.11.220.460
4qo9627Serine/threonine-protein kinase 242.7.11.10.460
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.459
1w0xOLOCyclin-dependent kinase 22.7.11.220.459
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.459
3qu0X40Cyclin-dependent kinase 22.7.11.220.459
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.459
3tucFPWTyrosine-protein kinase SYK2.7.10.20.459
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.459
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.459
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
1oirHDYCyclin-dependent kinase 22.7.11.220.458
2b55D31Cyclin-dependent kinase 22.7.11.220.458
2j0m4STFocal adhesion kinase 12.7.10.20.458
2w06FRVCyclin-dependent kinase 22.7.11.220.458
3qzgX67Cyclin-dependent kinase 22.7.11.220.458
3r7yZ04Cyclin-dependent kinase 22.7.11.220.458
3rk708ZCyclin-dependent kinase 22.7.11.220.458
4aqc88ATyrosine-protein kinase JAK2/0.458
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.458
4fkr45KCyclin-dependent kinase 22.7.11.220.458
4uyf73BBromodomain-containing protein 2/0.458
1gteFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.457
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.457
2pvlP55Casein kinase II subunit alpha2.7.11.10.457
2vd5BI8Myotonin-protein kinase2.7.11.10.457
3r7iX9ICyclin-dependent kinase 22.7.11.220.457
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.457
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.457
4gk3L87Ephrin type-A receptor 32.7.10.10.457
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.457
4qgiROCGag-Pol polyprotein3.4.23.160.457
1idb0DOGag-Pol polyprotein/0.456
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.456
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.456
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.456
2cchATPCyclin-dependent kinase 22.7.11.220.456
2w05FRTCyclin-dependent kinase 22.7.11.220.456
4fki09KCyclin-dependent kinase 22.7.11.220.456
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.456
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.456
1urwI1PCyclin-dependent kinase 22.7.11.220.455
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.455
2b7aIZATyrosine-protein kinase JAK2/0.455
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.455
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.455
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.455
3r7vZ02Cyclin-dependent kinase 22.7.11.220.455
3raiX85Cyclin-dependent kinase 22.7.11.220.455
3tqhNDPQuinone oxidoreductase/0.455
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.455
4erwSTUCyclin-dependent kinase 22.7.11.220.455
4hge15VTyrosine-protein kinase JAK2/0.455
1g5sI17Cyclin-dependent kinase 22.7.11.220.454
1oitHDTCyclin-dependent kinase 22.7.11.220.454
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.454
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.454
2qi3MZ5Gag-Pol polyprotein/0.454
3du8553Glycogen synthase kinase-3 beta2.7.11.260.454
3nga3NGCasein kinase II subunit alpha2.7.11.10.454
4fkpLS5Cyclin-dependent kinase 22.7.11.220.454
1c70L75Protease/0.453
1v1k3FPCyclin-dependent kinase 22.7.11.220.453
1zrzBI1Protein kinase C iota type2.7.11.130.453
2a0cCK9Cyclin-dependent kinase 22.7.11.220.453
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.453
2xa4AZ5Tyrosine-protein kinase JAK2/0.453
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.453
3r1yX76Cyclin-dependent kinase 22.7.11.220.453
3r6xX84Cyclin-dependent kinase 22.7.11.220.453
3r8pZ46Cyclin-dependent kinase 22.7.11.220.453
3rjc06ZCyclin-dependent kinase 22.7.11.220.453
3rvg17PTyrosine-protein kinase JAK2/0.453
4a6cQG9Gag-Pol polyprotein3.4.23.160.453
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.453
4fks46KCyclin-dependent kinase 22.7.11.220.453
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.453
1h1s4SPCyclin-dependent kinase 22.7.11.220.452
2btrU73Cyclin-dependent kinase 22.7.11.220.452
2henADPEphrin type-B receptor 22.7.10.10.452
2i40BLZCyclin-dependent kinase 22.7.11.220.452
2ojj82AMitogen-activated protein kinase 12.7.11.240.452
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.452
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.452
3d1xROCGag-Pol polyprotein3.4.23.160.452
3my5RFZCyclin-dependent kinase 22.7.11.220.452
4dh60KNBeta-secretase 13.4.23.460.452
4ek610KCyclin-dependent kinase 22.7.11.220.452
4gub0Y4Casein kinase II subunit alpha2.7.11.10.452
4ix6ADPUncharacterized protein/0.452
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.452
1h1r6CPCyclin-dependent kinase 22.7.11.220.451
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.451
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.451
3ddqRRCCyclin-dependent kinase 22.7.11.220.451
3ka0MK3MAP kinase-activated protein kinase 22.7.11.10.451
3lpbNVBTyrosine-protein kinase JAK2/0.451
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.451
3r7eX88Cyclin-dependent kinase 22.7.11.220.451
3tiz3TICyclin-dependent kinase 22.7.11.220.451
4ez50RSCyclin-dependent kinase 62.7.11.220.451
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.451
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.451
1ebyBEBGag-Pol polyprotein3.4.23.160.450
2pym1UNGag-Pol polyprotein3.4.23.160.450
2r64740Cyclin-dependent kinase 22.7.11.220.450
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.450
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.450
3qtuX44Cyclin-dependent kinase 22.7.11.220.450
3s1h56ZCyclin-dependent kinase 22.7.11.220.450
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.450
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.450
1ke5LS1Cyclin-dependent kinase 22.7.11.220.449
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.449
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.449
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.449
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.449
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.449
3qtzX42Cyclin-dependent kinase 22.7.11.220.449
4bcmT7ZCyclin-dependent kinase 22.7.11.220.449
4bcoT6QCyclin-dependent kinase 22.7.11.220.449
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.449
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.449
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.449
4kbc1QJCasein kinase I isoform delta2.7.11.10.449
1sbgIM1Gag-Pol polyprotein/0.448
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.448
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.448
2itvANPEpidermal growth factor receptor2.7.10.10.448
2zoq5IDMitogen-activated protein kinase 32.7.11.240.448
3ig7EFPCyclin-dependent kinase 22.7.11.220.448
3nynSGVG protein-coupled receptor kinase 62.7.11.160.448
3qtwX3ACyclin-dependent kinase 22.7.11.220.448
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.448
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.448
1c6zROCProtease/0.447
1k6pXN3Gag-Pol polyprotein3.4.23.160.447
1pyePM1Cyclin-dependent kinase 22.7.11.220.447
2uzoC62Cyclin-dependent kinase 22.7.11.220.447
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.447
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.447
3r8vZ62Cyclin-dependent kinase 22.7.11.220.447
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.447
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.447
4bgh3I6Cyclin-dependent kinase 22.7.11.220.447
4loqSB4Mitogen-activated protein kinase 14/0.447
4njvRITProtease/0.447
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.447
1gii1PUCyclin-dependent kinase 22.7.11.220.446
1h1q2A6Cyclin-dependent kinase 22.7.11.220.446
1mesDMPGag-Pol polyprotein3.4.23.160.446
2avvMK1Gag-Pol polyprotein3.4.23.160.446
2ca0PXICytochrome P450 monooxygenase PikC/0.446
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.446
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.446
2izuP01Casein kinase I isoform gamma-32.7.11.10.446
2q631UNGag-Pol polyprotein3.4.23.160.446
3a62STURibosomal protein S6 kinase beta-12.7.11.10.446
3c4xATPRhodopsin kinase/0.446
4bcpT3CCyclin-dependent kinase 22.7.11.220.446
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.446
4dt9GMPAPH(2'')-Id/0.446
4l9i8PRRhodopsin kinase/0.446
1pxlCK4Cyclin-dependent kinase 22.7.11.220.445
1wbk568Pol protein/0.445
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.445
2pvmP29Casein kinase II subunit alpha2.7.11.10.445
2xmyCDKCyclin-dependent kinase 22.7.11.220.445
3vjoANPEpidermal growth factor receptor2.7.10.10.445
4a9sRU9Serine/threonine-protein kinase Chk22.7.11.10.445
4c4jX21Dual specificity protein kinase TTK2.7.12.10.445
4c57FEFCyclin-G-associated kinase2.7.11.10.445
4eol1ROCyclin-dependent kinase 22.7.11.220.445
4fkv61KCyclin-dependent kinase 22.7.11.220.445
4hgt15GCasein kinase I isoform delta2.7.11.10.445
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.445
5e8xSTUTGF-beta receptor type-12.7.11.300.445
1b6pPI7Gag-Pol polyprotein3.4.23.160.444
1hsgMK1Gag-Pol polyprotein/0.444
1mtrPI6Gag-Pol polyprotein3.4.23.160.444
2iw94SPCyclin-dependent kinase 22.7.11.220.444
2izt23DCasein kinase I isoform gamma-32.7.11.10.444
2j7t274Serine/threonine-protein kinase 102.7.11.10.444
2uzbC75Cyclin-dependent kinase 22.7.11.220.444
3oxw017Gag-Pol polyprotein3.4.23.160.444
3qxpX64Cyclin-dependent kinase 22.7.11.220.444
4b99R4LMitogen-activated protein kinase 72.7.11.240.444
4bdaVFBSerine/threonine-protein kinase Chk22.7.11.10.444
1bv7XV6Gag-Pol polyprotein3.4.23.160.443
1ckpPVBCyclin-dependent kinase 22.7.11.220.443
1pkdUCNCyclin-dependent kinase 22.7.11.220.443
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.443
2q7vFADThioredoxin reductase/0.443
2r3wG3GGag-Pol polyprotein3.4.23.160.443
2z7lS91Mitogen-activated protein kinase 12.7.11.240.443
3lctADPALK tyrosine kinase receptor2.7.10.10.443
3uyt0CKCasein kinase I isoform delta2.7.11.10.443
3w32W32Epidermal growth factor receptor2.7.10.10.443
4eop1ROCyclin-dependent kinase 22.7.11.220.443
4fz70VHTyrosine-protein kinase SYK2.7.10.20.443
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.443
4jqeANPCasein kinase II subunit alpha2.7.11.10.443
4lyn1YGCyclin-dependent kinase 22.7.11.220.443
1bygSTUTyrosine-protein kinase CSK/0.442
1c6yMK1Protease/0.442
1cdeGARPhosphoribosylglycinamide formyltransferase/0.442
1d4kPI8Gag-Pol polyprotein3.4.23.160.442
1jld0PPGag-Pol polyprotein/0.442
1rwbNADGlucose 1-dehydrogenase1.1.1.470.442
2fde385Gag-Pol polyprotein3.4.23.160.442
2ftoCB3Thymidylate synthase/0.442
3frqERYErythromycin resistance repressor protein/0.442
3gubGUBDeath-associated protein kinase 12.7.11.10.442
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.442
4ek816KCyclin-dependent kinase 22.7.11.220.442
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.442
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.442
4hjoAQ4Epidermal growth factor receptor2.7.10.10.442
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.442
5cu6ATPCasein kinase II subunit alpha2.7.11.10.442
1ebwBEIGag-Pol polyprotein3.4.23.160.441
1ke7LS3Cyclin-dependent kinase 22.7.11.220.441
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.441
1z1hHBBGag-Pol polyprotein3.4.23.160.441
2eb3ANPEpidermal growth factor receptor2.7.10.10.441
2qnqQN3Gag-Pol polyprotein3.4.23.160.441
2w17I19Cyclin-dependent kinase 22.7.11.220.441
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.441
3cyxROCGag-Pol polyprotein3.4.23.160.441
3eb0DRKUncharacterized protein/0.441
3iggEFQCyclin-dependent kinase 22.7.11.220.441
3nwxKVSGag-Pol polyprotein3.4.23.160.441
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.441
3qqlX03Cyclin-dependent kinase 22.7.11.220.441
3qwkX62Cyclin-dependent kinase 22.7.11.220.441
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.441
4at0FADPossible succinate dehydrogenase/0.441
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.441
4fv7E94Mitogen-activated protein kinase 12.7.11.240.441
4tuvCPZCytochrome P450 1191.140.441
5aniES4Cyclin-dependent kinase 22.7.11.220.441
1hiiC20Gag-Pol polyprotein/0.440
1npa3NHGag-Pol polyprotein3.4.23.160.440
1npwLGZGag-Pol polyprotein3.4.23.160.440
1sguMK1Gag-Pol polyprotein3.4.23.160.440
2r3r6SCCyclin-dependent kinase 22.7.11.220.440
2vtqLZACyclin-dependent kinase 22.7.11.220.440
3pe2E1BCasein kinase II subunit alpha2.7.11.10.440
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
4ap3FADSteroid monooxygenase/0.440
4o71CPBBromodomain-containing protein 4/0.440
5jlaNADPutative short-chain dehydrogenase/reductase/0.440
5upjUINGag-Pol polyprotein/0.440