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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3umxQ18Serine/threonine-protein kinase pim-12.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3umxQ18Serine/threonine-protein kinase pim-12.7.11.11.000
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.651
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.627
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.618
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.613
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.612
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.605
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.604
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.604
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.604
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.602
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.599
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.591
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.590
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.585
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.584
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.584
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.582
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.581
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.579
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.578
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.578
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.577
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.577
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.576
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.575
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.573
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.570
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.566
3umw596Serine/threonine-protein kinase pim-12.7.11.10.565
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.563
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.563
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.563
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.558
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.557
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.555
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.554
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.551
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.550
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.549
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.548
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.548
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.542
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.540
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.539
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.531
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.530
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.519
2wihP48Cyclin-dependent kinase 22.7.11.220.517
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.517
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
1xjdSTUProtein kinase C theta type2.7.11.130.514
4j99ACPFibroblast growth factor receptor 2/0.512
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.510
4gmy0X5Tyrosine-protein kinase JAK2/0.509
3bqr4RBDeath-associated protein kinase 3/0.507
5auvAGIDeath-associated protein kinase 12.7.11.10.507
5av2KMPDeath-associated protein kinase 12.7.11.10.507
2ckeIQUDeath-associated protein kinase 2/0.506
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.506
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.506
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.505
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.505
2bujSTUSerine/threonine-protein kinase 16/0.503
3uyt0CKCasein kinase I isoform delta2.7.11.10.502
4bgg844Activin receptor type-12.7.11.300.502
4dymIYZActivin receptor type-12.7.11.300.502
3sheI85MAP kinase-activated protein kinase 32.7.11.10.501
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.501
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.501
4yuqKS1Calmodulin-like domain protein kinase/0.501
3lltANPProtein serine/threonine kinase-1/0.500
4fob0USALK tyrosine kinase receptor2.7.10.10.500
5auwQUEDeath-associated protein kinase 12.7.11.10.500
2yaaATPDeath-associated protein kinase 2/0.499
3gubGUBDeath-associated protein kinase 12.7.11.10.499
3q9xEMOCasein kinase II subunit alpha2.7.11.10.499
4i22IREEpidermal growth factor receptor2.7.10.10.498
4xlvACPInsulin receptor2.7.10.10.498
5cvfATPCasein kinase II subunit alpha2.7.11.10.498
4jia1K3Tyrosine-protein kinase JAK2/0.496
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.495
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.495
4bbe3O4Tyrosine-protein kinase JAK2/0.495
4erwSTUCyclin-dependent kinase 22.7.11.220.495
1aq1STUCyclin-dependent kinase 22.7.11.220.494
2j0m4STFocal adhesion kinase 12.7.10.20.493
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.493
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.493
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.492
1wvxBD4Death-associated protein kinase 12.7.11.10.491
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.491
4b99R4LMitogen-activated protein kinase 72.7.11.240.491
4riyADPEpidermal growth factor receptor2.7.10.10.491
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.491
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.490
2j0k4STFocal adhesion kinase 12.7.10.20.490
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.490
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.490
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.490
4j95ACPFibroblast growth factor receptor 2/0.490
5av3KMPDeath-associated protein kinase 12.7.11.10.490
1eh4IC1Casein kinase I homolog 12.7.11.10.489
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.489
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.489
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.489
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.488
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.487
2uzbC75Cyclin-dependent kinase 22.7.11.220.487
3at4CCKCasein kinase II subunit alpha2.7.11.10.487
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.487
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.487
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.486
3ormAGSSerine/threonine protein kinase/0.486
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.485
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.485
2iw84SPCyclin-dependent kinase 22.7.11.220.485
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.485
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.485
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.485
1jklANPDeath-associated protein kinase 12.7.11.10.484
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.484
3mpaSB2Mitogen-activated protein kinase 14/0.484
4ic7ANPMitogen-activated protein kinase 72.7.11.240.484
1u4dDBQActivated CDC42 kinase 1/0.483
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.483
3a7hATPSerine/threonine-protein kinase 242.7.11.10.483
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
4kbk1QGCasein kinase I isoform delta2.7.11.10.483
2x1nX1NCyclin-dependent kinase 22.7.11.220.482
4grb0XGCasein kinase II subunit alpha2.7.11.10.482
4hvi19STyrosine-protein kinase JAK32.7.10.20.482
4jq8KJ8Epidermal growth factor receptor2.7.10.10.482
4wboANWRhodopsin kinase/0.482
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.481
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.481
2cchATPCyclin-dependent kinase 22.7.11.220.481
3c4xATPRhodopsin kinase/0.481
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.481
3kf7L9GMitogen-activated protein kinase 14/0.481
3mtfA3FActivin receptor type-12.7.11.300.481
3u4uLNHCasein kinase II subunit alpha2.7.11.10.481
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.481
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.481
4e730NRMitogen-activated protein kinase 82.7.11.240.481
1zys199Serine/threonine-protein kinase Chk12.7.11.10.480
3du8553Glycogen synthase kinase-3 beta2.7.11.260.480
5cu6ATPCasein kinase II subunit alpha2.7.11.10.480
1bygSTUTyrosine-protein kinase CSK/0.479
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.479
3t8oATPRhodopsin kinase/0.479
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.479
4kba1QMCasein kinase I isoform delta2.7.11.10.479
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.478
2chlDKICasein kinase I isoform gamma-32.7.11.10.478
3gc9B45Mitogen-activated protein kinase 112.7.11.240.478
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.478
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.478
3w33W19Epidermal growth factor receptor2.7.10.10.478
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.478
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.478
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.478
4qmlANPSerine/threonine-protein kinase 242.7.11.10.478
5auxKMPDeath-associated protein kinase 12.7.11.10.478
2hog710Serine/threonine-protein kinase Chk12.7.11.10.477
2itpAEEEpidermal growth factor receptor2.7.10.10.477
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.477
3gu7ADPDeath-associated protein kinase 12.7.11.10.477
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.477
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.477
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.477
4g1wG1WMitogen-activated protein kinase 82.7.11.240.477
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.477
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.477
1p4fDRGDeath-associated protein kinase 12.7.11.10.476
1yvj4STTyrosine-protein kinase JAK32.7.10.20.476
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.476
2j0j4STFocal adhesion kinase 12.7.10.20.476
2p33J07Mitogen-activated protein kinase 102.7.11.240.476
3igoANPCalmodulin-domain protein kinase 1, putative/0.476
3w2sW2REpidermal growth factor receptor2.7.10.10.476
3zh8C58Protein kinase C iota type2.7.11.130.476
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.476
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.475
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.475
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.475
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.475
4cd0AWJALK tyrosine kinase receptor2.7.10.10.475
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.475
4iarERM5-hydroxytryptamine receptor 1B/0.475
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.475
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.475
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.474
3dfcANPDeath-associated protein kinase 12.7.11.10.474
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.474
4cfnJYMCyclin-dependent kinase 22.7.11.220.474
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.474
3nga3NGCasein kinase II subunit alpha2.7.11.10.473
2etm7PYFocal adhesion kinase 12.7.10.20.472
2ijmADPFocal adhesion kinase 12.7.10.20.472
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.472
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.472
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.472
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.472
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.472
4ez50RSCyclin-dependent kinase 62.7.11.220.472
4fod0UVALK tyrosine kinase receptor2.7.10.10.472
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.472
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.471
2i40BLZCyclin-dependent kinase 22.7.11.220.471
3i60E86Mitogen-activated protein kinase 12.7.11.240.471
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.471
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.471
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.471
2pulACPMethylthioribose kinase2.7.1.1000.470
2pvnP63Casein kinase II subunit alpha2.7.11.10.470
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.470
3bu5ATPInsulin receptor2.7.10.10.470
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.470
3oroAGSSerine/threonine protein kinase/0.470
4ansVGHALK tyrosine kinase receptor2.7.10.10.470
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4dgnLU2Casein kinase II subunit alpha2.7.11.10.470
4gw83RASerine/threonine-protein kinase pim-12.7.11.10.470
4nj32KDCyclin-dependent kinase 22.7.11.220.470
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.470
1oiyN41Cyclin-dependent kinase 22.7.11.220.469
1pjkANPCasein kinase II subunit alpha2.7.11.10.469
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.469
2iw94SPCyclin-dependent kinase 22.7.11.220.469
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.469
3iw4LW4Protein kinase C alpha type2.7.11.130.469
4anqVGHALK tyrosine kinase receptor2.7.10.10.469
5cvhADPCasein kinase II subunit alpha2.7.11.10.469
1h1r6CPCyclin-dependent kinase 22.7.11.220.468
1pkdUCNCyclin-dependent kinase 22.7.11.220.468
1zrzBI1Protein kinase C iota type2.7.11.130.468
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.468
2h96893Mitogen-activated protein kinase 82.7.11.240.468
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.468
2c7xNRBCytochrome P450 monooxygenase PikC/0.467
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.467
4anmWULCasein kinase II subunit alpha2.7.11.10.467
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.467
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.467
4fkv61KCyclin-dependent kinase 22.7.11.220.467
4hvh19RTyrosine-protein kinase JAK32.7.10.20.467
1pmn984Mitogen-activated protein kinase 102.7.11.240.466
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.466
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.466
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.466
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.466
3gu6ADPDeath-associated protein kinase 12.7.11.10.466
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.466
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.466
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.466
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.466
4hni16WCasein kinase I isoform epsilon2.7.11.10.466
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.465
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.465
2izuP01Casein kinase I isoform gamma-32.7.11.10.465
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.465
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.465
3a60STURibosomal protein S6 kinase beta-12.7.11.10.465
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.465
4hnf16WCasein kinase I isoform delta2.7.11.10.465
4o0wADNAurora kinase A2.7.11.10.465
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.464
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.464
2izsBRQCasein kinase I isoform gamma-32.7.11.10.464
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.464
3be9P04Casein kinase II subunit alpha2.7.11.10.464
3emg685Tyrosine-protein kinase SYK2.7.10.20.464
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.464
4c4g7RODual specificity protein kinase TTK2.7.12.10.464
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.464
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.464
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.464
4q5hANPProtein kinase OspG2.70.464
4wkqIREEpidermal growth factor receptor2.7.10.10.464
2q59240Peroxisome proliferator-activated receptor gamma/0.463
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.463
2znq401Peroxisome proliferator-activated receptor delta/0.463
3oom507Activin receptor type-12.7.11.300.463
4c4jX21Dual specificity protein kinase TTK2.7.12.10.463
4ix6ADPUncharacterized protein/0.463
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.463
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.463
4qo9627Serine/threonine-protein kinase 242.7.11.10.463
5cshATPCasein kinase II subunit alpha2.7.11.10.463
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4btjATPTau-tubulin kinase 12.7.11.10.462
4foc0UUALK tyrosine kinase receptor2.7.10.10.462
4hyu1BKMitogen-activated protein kinase 82.7.11.240.462
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.462
4m15ADPTyrosine-protein kinase ITK/TSK2.7.10.20.462
4qmySTUSerine/threonine-protein kinase 242.7.11.10.462
1oguST8Cyclin-dependent kinase 22.7.11.220.461
2acxANPG protein-coupled receptor kinase 62.7.11.160.461
2c475IDCasein kinase I isoform gamma-2/0.461
2w17I19Cyclin-dependent kinase 22.7.11.220.461
2xb7GUIALK tyrosine kinase receptor2.7.10.10.461
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.461
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.461
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.461
4fz60VGTyrosine-protein kinase SYK2.7.10.20.461
4hgt15GCasein kinase I isoform delta2.7.11.10.461
5av4GENDeath-associated protein kinase 12.7.11.10.461
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.460
2ghmLICMitogen-activated protein kinase 14/0.460
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.460
4c4iX20Dual specificity protein kinase TTK2.7.12.10.460
4ccbOFGALK tyrosine kinase receptor2.7.10.10.460
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.460
5aabVGHALK tyrosine kinase receptor2.7.10.10.460
1e9hINRCyclin-dependent kinase 22.7.11.220.459
1gih1PUCyclin-dependent kinase 22.7.11.220.459
1h1s4SPCyclin-dependent kinase 22.7.11.220.459
2itnANPEpidermal growth factor receptor2.7.10.10.459
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.459
2w05FRTCyclin-dependent kinase 22.7.11.220.459
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.459
3owl19ECasein kinase II subunit alpha2.7.11.10.459
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.459
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.459
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.459
4aa5NQBMitogen-activated protein kinase 14/0.459
4c4h7RODual specificity protein kinase TTK2.7.12.10.459
4fv9E71Mitogen-activated protein kinase 12.7.11.240.459
4fx360KCyclin-dependent kinase 22.7.11.220.459
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.459
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.458
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.458
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.458
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.458
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4fz70VHTyrosine-protein kinase SYK2.7.10.20.458
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.457
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.457
3q5iANPProtein kinase, putative/0.457
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.457
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4aqkADPInositol-pentakisphosphate 2-kinase2.7.1.1580.457
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.457
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.457
5auzGENDeath-associated protein kinase 12.7.11.10.457
1oiuN76Cyclin-dependent kinase 22.7.11.220.456
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.456
2c5nCK8Cyclin-dependent kinase 22.7.11.220.456
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.456
2xa4AZ5Tyrosine-protein kinase JAK2/0.456
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.456
3ddpRC8Cyclin-dependent kinase 22.7.11.220.456
3hmm855TGF-beta receptor type-12.7.11.300.456
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.456
3nux3NVCyclin-dependent kinase 62.7.11.220.456
3nynSGVG protein-coupled receptor kinase 62.7.11.160.456
4f630S7Fibroblast growth factor receptor 1/0.456
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4ux9ANPMitogen-activated protein kinase 82.7.11.240.456
1ir3ANPInsulin receptor2.7.10.10.455
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.455
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.455
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.455
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.455
2hk51BMTyrosine-protein kinase HCK2.7.10.20.455
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.455
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3c50ADPRhodopsin kinase/0.455
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.455
3gxlQIGTGF-beta receptor type-12.7.11.300.455
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.455
3sp9IL2Peroxisome proliferator-activated receptor delta/0.455
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
5aacVGHALK tyrosine kinase receptor2.7.10.10.455
5ap57RODual specificity protein kinase TTK2.7.12.10.455
5f0a1FBcGMP-dependent protein kinase, putative/0.455
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.454
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2izt23DCasein kinase I isoform gamma-32.7.11.10.454
2om9AJAPeroxisome proliferator-activated receptor gamma/0.454
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.454
3nwyGTPUridylate kinase/0.454
4bcqTJFCyclin-dependent kinase 22.7.11.220.454
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.454
4bi0Z0WDual specificity protein kinase TTK2.7.12.10.454
4c4f7CEDual specificity protein kinase TTK2.7.12.10.454
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.454
4kb81QNCasein kinase I isoform delta2.7.11.10.454
5aaaVGHALK tyrosine kinase receptor2.7.10.10.454
1cm8ANPMitogen-activated protein kinase 12/0.453
1m2pHNACasein kinase II subunit alpha2.7.11.10.453
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.453
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.453
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.453
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.453
3a4pDFQHepatocyte growth factor receptor2.7.10.10.453
3d7tSTUTyrosine-protein kinase CSK/0.453
3hllI45Mitogen-activated protein kinase 14/0.453
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.453
3my5RFZCyclin-dependent kinase 22.7.11.220.453
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.453
3zewSTUEphrin type-B receptor 42.7.10.10.453
4a99FADTetX family tetracycline inactivation enzyme/0.453
4l9i8PRRhodopsin kinase/0.453
1qxlFR8Adenosine deaminase3.5.4.40.452
1u54ACPActivated CDC42 kinase 1/0.452
2b52D42Cyclin-dependent kinase 22.7.11.220.452
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.452
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.452
2uzdC85Cyclin-dependent kinase 22.7.11.220.452
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.452
3a7jADPSerine/threonine-protein kinase 242.7.11.10.452
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.452
3kvxFMYMitogen-activated protein kinase 102.7.11.240.452
3mvl38PMitogen-activated protein kinase 14/0.452
3nszANPCasein kinase II subunit alpha2.7.11.10.452
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.452
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.452
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.452
4f650S9Fibroblast growth factor receptor 1/0.452
4fyn0VETyrosine-protein kinase SYK2.7.10.20.452
4jboWPHAurora kinase A2.7.11.10.452
4jqeANPCasein kinase II subunit alpha2.7.11.10.452
1v0pPVBCell division control protein 2 homolog2.7.11.220.451
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.451
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
4hvg19QTyrosine-protein kinase JAK32.7.10.20.451
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.451
4qmzB49Serine/threonine-protein kinase 242.7.11.10.451
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.450
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.450
2ojj82AMitogen-activated protein kinase 12.7.11.240.450
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.450
2py3ACPFibroblast growth factor receptor 2/0.450
2wpa889Cyclin-dependent kinase 22.7.11.220.450
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.450
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.450
4bcmT7ZCyclin-dependent kinase 22.7.11.220.450
4eok4SPCyclin-dependent kinase 22.7.11.220.450
4gu610NFocal adhesion kinase 12.7.10.20.450
4iaq2GM5-hydroxytryptamine receptor 1B/0.450
4iwd1JCHepatocyte growth factor receptor2.7.10.10.450
5drdATPAurora kinase A2.7.11.10.450
2etrY27Rho-associated protein kinase 12.7.11.10.449
2vv9IM9Cyclin-dependent kinase 22.7.11.220.449
2xnbY8LCyclin-dependent kinase 22.7.11.220.449
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.449
2yn8STUEphrin type-B receptor 42.7.10.10.449
3pe2E1BCasein kinase II subunit alpha2.7.11.10.449
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.449
3s4qNK0Mitogen-activated protein kinase 14/0.449
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.449
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.449
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.449
1jstATPCyclin-dependent kinase 22.7.11.220.448
2excJNKMitogen-activated protein kinase 102.7.11.240.448
2j0lANPFocal adhesion kinase 12.7.10.20.448
2vu3LZECyclin-dependent kinase 22.7.11.220.448
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.448
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.448
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.448
3ddqRRCCyclin-dependent kinase 22.7.11.220.448
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.448
3zdu38RCyclin-dependent kinase-like 32.7.11.220.448
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.448
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.448
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.448
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.448
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.448
4wa9AXITyrosine-protein kinase ABL12.7.10.20.448
4wsqKSAAP2-associated protein kinase 12.7.11.10.448
1ee0CAA2-pyrone synthase/0.447
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.447
2f2cAP9Cyclin-dependent kinase 62.7.11.220.447
2pvlP55Casein kinase II subunit alpha2.7.11.10.447
2pz5ACPFibroblast growth factor receptor 2/0.447
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.447
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.447
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.447
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.447
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.447
4gu94GUFocal adhesion kinase 12.7.10.20.447
4kiq1RAMitogen-activated protein kinase 14/0.447
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.447
1pmv537Mitogen-activated protein kinase 102.7.11.240.446
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.446
2w4jADPDeath-associated protein kinase 12.7.11.10.446
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.446
2yiqYIQSerine/threonine-protein kinase Chk22.7.11.10.446
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.446
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3otuBI43-phosphoinositide-dependent protein kinase 12.7.11.10.446
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.446
3rni21ZCyclin-dependent kinase 22.7.11.220.446
3vryB43Tyrosine-protein kinase HCK2.7.10.20.446
3wowANPCasein kinase II subunit alpha2.7.11.10.446
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.446
4hge15VTyrosine-protein kinase JAK2/0.446
4jbpYPHAurora kinase A2.7.11.10.446
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.446
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.446
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.446
4y93746Tyrosine-protein kinase/0.446
5ap7SVEDual specificity protein kinase TTK2.7.12.10.446
1mruAGSSerine/threonine-protein kinase PknB2.7.11.10.445
2d3mCOA5,7-dihydroxy-2-methylchromone synthase2.3.1.2160.445
2eufLQQCyclin-dependent kinase 62.7.11.220.445
2jkoBIJFocal adhesion kinase 12.7.10.20.445
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2w2lNADD-mandelate dehydrogenase/0.445
2x6dX6DAurora kinase A2.7.11.10.445
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.445
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.445
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.445
3eb0DRKUncharacterized protein/0.445
3lctADPALK tyrosine kinase receptor2.7.10.10.445
3lfnA27Cyclin-dependent kinase 22.7.11.220.445
4b7dQLECytochrome P450 monooxygenase PikC/0.445
4e4m0NHTyrosine-protein kinase JAK2/0.445
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.445
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.445
4g170VNCasein kinase I isoform gamma-32.7.11.10.445
4gub0Y4Casein kinase II subunit alpha2.7.11.10.445
4nka2K7Fibroblast growth factor receptor 1/0.445
5dosATPAurora kinase A2.7.11.10.445
5e8ySTUTGF-beta receptor type-22.7.11.300.445
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.444
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.444
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.444
2uzeC95Cyclin-dependent kinase 22.7.11.220.444
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2w1fL0FAurora kinase A2.7.11.10.444
3a62STURibosomal protein S6 kinase beta-12.7.11.10.444
3gggNADPrephenate dehydrogenase/0.444
3lq5SLQCyclin-dependent kinase 92.7.11.220.444
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.444
3tnwF18Cyclin-dependent kinase 22.7.11.220.444
3tucFPWTyrosine-protein kinase SYK2.7.10.20.444
3vf80JETyrosine-protein kinase SYK2.7.10.20.444
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.444
4d58BI9Focal adhesion kinase 12.7.10.20.444
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.444
4gk3L87Ephrin type-A receptor 32.7.10.10.444
4nk92K5Fibroblast growth factor receptor 1/0.444
4qmpDKISerine/threonine-protein kinase 242.7.11.10.444
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.444
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.443
2j7t274Serine/threonine-protein kinase 102.7.11.10.443
2vgoAD5Aurora kinase B-A2.7.11.10.443
3cgoJNOMitogen-activated protein kinase 102.7.11.240.443
3eljGS7Mitogen-activated protein kinase 82.7.11.240.443
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3qqkX02Cyclin-dependent kinase 22.7.11.220.443
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4c61LMMTyrosine-protein kinase JAK2/0.443
4i4e1BQFocal adhesion kinase 12.7.10.20.443
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.443
4othDRNSerine/threonine-protein kinase N1/0.443
1xl2189Gag-Pol polyprotein3.4.23.160.442
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2vagV25Dual specificity protein kinase CLK12.7.12.10.442
2wotZZGTGF-beta receptor type-12.7.11.300.442
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.442
3qfvNM7Serine/threonine-protein kinase MRCK beta2.7.11.10.442
3vquO22Dual specificity protein kinase TTK2.7.12.10.442
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.442
4fuxE75Mitogen-activated protein kinase 12.7.11.240.442
4gk2L66Ephrin type-A receptor 32.7.10.10.442
4izy1J2Mitogen-activated protein kinase 82.7.11.240.442
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.442
4ysjADPCalmodulin-like domain protein kinase/0.442
5e8wSTUTGF-beta receptor type-12.7.11.300.442
1di8DTQCyclin-dependent kinase 22.7.11.220.441
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.441
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.441
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.441
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2q9fC3SCholesterol 24-hydroxylase/0.441
2qo9ANPEphrin type-A receptor 32.7.10.10.441
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.441
2yfxVGHALK tyrosine kinase receptor2.7.10.10.441
2z7qACPRibosomal protein S6 kinase alpha-12.7.11.10.441
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.441
3mtlFEFCyclin-dependent kinase 162.7.11.220.441
3nup3NUCyclin-dependent kinase 62.7.11.220.441
3s2pPMUCyclin-dependent kinase 22.7.11.220.441
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.441
4eon1ROCyclin-dependent kinase 22.7.11.220.441
4fnyI3KALK tyrosine kinase receptor2.7.10.10.441
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.441
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.441
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.441
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.441
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.441
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1mq4ADPAurora kinase A2.7.11.10.440
2b55D31Cyclin-dependent kinase 22.7.11.220.440
2bfyH1NAurora kinase B-A2.7.11.10.440
2hw2RFPRifampin ADP-ribosyl transferase/0.440
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.440
2jedLG8Protein kinase C theta type2.7.11.130.440
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.440
2wxvWXVCyclin-dependent kinase 22.7.11.220.440
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.440
3iok1P6Tyrosine-protein kinase JAK2/0.440
3poz03PEpidermal growth factor receptor2.7.10.10.440
3uli1N3Cyclin-dependent kinase 22.7.11.220.440
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.440
3zep1NXTyrosine-protein kinase JAK32.7.10.20.440
4fmqANPMitogen-activated protein kinase 12.7.11.240.440
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.440
4o71CPBBromodomain-containing protein 4/0.440