sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3r4n | FU5 | Heat shock protein HSP 90-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 1.000 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.648 | |
| 1u0z | RDC | Endoplasmin | / | 0.634 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.626 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.626 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.625 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.623 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.616 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.614 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.613 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.611 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.610 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.610 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.608 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.607 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.603 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.601 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.600 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.599 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.594 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.594 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.593 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.591 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.590 | |
| 1u2o | NEC | Endoplasmin | / | 0.589 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.588 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.588 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.588 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.587 | |
| 3t2s | AGS | Heat shock protein HSP 90-alpha | / | 0.586 | |
| 1qy8 | RDI | Endoplasmin | / | 0.585 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.583 | |
| 1u0y | PA7 | Endoplasmin | / | 0.581 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.581 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.581 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.581 | |
| 1ysz | NEC | Endoplasmin | / | 0.580 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.577 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.577 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.577 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.577 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.576 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.576 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.576 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.575 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.575 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.575 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.573 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.572 | |
| 2gfd | RDA | Endoplasmin | / | 0.572 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.569 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.568 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.567 | |
| 2gqp | PA7 | Endoplasmin | / | 0.565 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.565 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.564 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.564 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.563 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.562 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.561 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.561 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.560 | |
| 1qy5 | NEC | Endoplasmin | / | 0.560 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.560 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.559 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.559 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.559 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.559 | |
| 2exl | GDM | Endoplasmin | / | 0.558 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.558 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.558 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.558 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.557 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.557 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.557 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.554 | |
| 2byi | 2DD | Heat shock protein HSP 90-alpha | / | 0.553 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.551 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.548 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.547 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.547 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.547 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.545 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.545 | |
| 1yet | GDM | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.542 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.542 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.542 | |
| 2hch | N5A | Endoplasmin | / | 0.541 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.538 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.536 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.534 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.534 | |
| 2hg1 | N5O | Endoplasmin | / | 0.534 | |
| 2xht | C0Y | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.533 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.533 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.532 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.532 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.531 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.529 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.528 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.527 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.523 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.522 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.522 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.522 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2o1u | ANP | Endoplasmin | / | 0.520 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.520 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 3ied | AN2 | HSP90 | / | 0.512 | |
| 2esa | GDM | Endoplasmin | / | 0.510 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.509 | |
| 2fyp | RDE | Endoplasmin | / | 0.507 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.507 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 4z1f | H71 | Heat shock protein 75 kDa, mitochondrial | / | 0.506 | |
| 1yt0 | ADP | Endoplasmin | / | 0.500 | |
| 2q8i | RDC | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial | 2.7.11.2 | 0.500 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.497 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.494 | |
| 2zdx | P4A | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.494 | |
| 2hkj | RDC | Type 2 DNA topoisomerase 6 subunit B | / | 0.492 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.490 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.489 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.486 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.485 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.484 | |
| 2o1v | ADP | Endoplasmin | / | 0.481 | |
| 2vwc | BC2 | ATP-dependent molecular chaperone HSP82 | / | 0.480 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.480 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.479 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.478 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.476 | |
| 2yi6 | 6QM | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.476 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.476 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.475 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 3crl | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.475 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 3tki | S25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.473 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.473 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.471 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.471 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.470 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.470 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.470 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.470 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.469 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.468 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.468 | |
| 3bvb | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 3zdu | 38R | Cyclin-dependent kinase-like 3 | 2.7.11.22 | 0.468 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 1z59 | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.467 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.467 | |
| 4oae | CLM | Uncharacterized protein | / | 0.467 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.467 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.466 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.463 | |
| 2xhx | T5M | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 4fcq | 2N6 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 4gu6 | 10N | Focal adhesion kinase 1 | 2.7.10.2 | 0.463 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.463 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.460 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.460 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.460 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.459 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.459 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.459 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.458 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.458 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.458 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.458 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.457 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.457 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.456 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.456 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.456 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.456 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.455 | |
| 2bu2 | ATP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.455 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.455 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.454 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.454 | |
| 2uwd | 2GG | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3dsz | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.454 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.454 | |
| 4nh9 | 2LC | Endoplasmin | / | 0.454 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.453 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.453 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.453 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.453 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.453 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.452 | |
| 2y3r | TRK | TamL | / | 0.452 | |
| 2yec | XQ0 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.452 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.451 | |
| 2fde | 385 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.451 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.451 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.450 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.450 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2ym6 | YM6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.450 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.450 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.450 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.450 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 3eyh | IZA | Tyrosine-protein kinase JAK1 | / | 0.449 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.449 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.448 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.448 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 0.448 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.448 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.448 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.448 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.448 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.447 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.447 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.447 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.447 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.446 | |
| 1eio | GCH | Gastrotropin | / | 0.446 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.446 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1llw | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.446 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.446 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.446 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.446 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.446 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.446 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.446 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.445 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.445 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.445 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.445 | |
| 4ful | 0VU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.445 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.445 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.444 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.444 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.444 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.444 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 4zp0 | DXC | Multidrug transporter MdfA | / | 0.444 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.443 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.443 | |
| 2qhc | AB1 | Protease | / | 0.443 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.443 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.443 | |
| 4xwt | U5P | Ribonuclease J | / | 0.443 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.443 | |
| 1c2t | NHS | Phosphoribosylglycinamide formyltransferase | / | 0.442 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.442 | |
| 1n49 | RIT | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.442 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.442 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.442 | |
| 3q92 | XNB | Ketohexokinase | / | 0.442 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.442 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 5ikq | JMS | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1nxk | STU | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.441 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rdw | LAR | Actin, alpha skeletal muscle | / | 0.441 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.441 | |
| 2jam | J60 | Calcium/calmodulin-dependent protein kinase type 1G | 2.7.11.17 | 0.441 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.441 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.441 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.441 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.441 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.441 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.441 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.441 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.441 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.441 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.441 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.441 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.441 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.441 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.441 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.441 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.440 | |
| 2qi3 | MZ5 | Gag-Pol polyprotein | / | 0.440 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.440 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.440 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 |