Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3onw | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
3onw | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 1.000 | |
4g5q | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.609 | |
3qi2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.557 | |
1gp2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.549 | |
3qe0 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.519 | |
5dha | GNP | GTP-binding nuclear protein Ran | / | 0.505 | |
1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.503 | |
3o26 | NDP | Salutaridine reductase | / | 0.500 | |
1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.499 | |
1w5t | ANP | ORC1-type DNA replication protein 2 | / | 0.499 | |
1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.498 | |
1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.498 | |
1bof | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.496 | |
2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.494 | |
4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.493 | |
2il2 | LIX | Renin | 3.4.23.15 | 0.487 | |
4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.486 | |
2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.485 | |
3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.485 | |
2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.483 | |
4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.483 | |
4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.483 | |
1m2o | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.482 | |
1xtr | GNP | GTP-binding protein Rheb | / | 0.482 | |
3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.482 | |
2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.481 | |
4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.481 | |
1sxj | ADP | Replication factor C subunit 5 | / | 0.480 | |
2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.480 | |
2xtn | GTP | GTPase IMAP family member 2 | / | 0.479 | |
4e03 | ADP | Plasmid partitioning protein ParF | / | 0.479 | |
2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.478 | |
2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.477 | |
3dl0 | AP5 | Adenylate kinase | / | 0.477 | |
3tjz | GNP | ADP-ribosylation factor 1 | / | 0.477 | |
1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.476 | |
2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.476 | |
3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.476 | |
1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.475 | |
1u0h | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.475 | |
1xts | GTP | GTP-binding protein Rheb | / | 0.475 | |
4loh | 1SY | Stimulator of interferon genes protein | / | 0.475 | |
3h86 | AP5 | Adenylate kinase | / | 0.474 | |
4cf1 | IY7 | Integrase | / | 0.474 | |
4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.474 | |
1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.473 | |
2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.472 | |
2gil | GTP | Ras-related protein Rab-6A | / | 0.472 | |
4a5l | NDP | Thioredoxin reductase | / | 0.472 | |
2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.471 | |
2pj4 | 414 | Carboxypeptidase B | / | 0.471 | |
3tox | NAP | Putative oxidoreductase | / | 0.471 | |
1jed | ADP | Sulfate adenylyltransferase | / | 0.470 | |
2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.470 | |
3f3s | NAD | Lambda-crystallin homolog | / | 0.470 | |
3lsi | FAD | Pyranose 2-oxidase | / | 0.470 | |
4die | C5P | Cytidylate kinase | / | 0.470 | |
4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.470 | |
4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.469 | |
4fid | GDP | G protein alpha subunit, putative | / | 0.469 | |
4lcj | NAD | C-terminal-binding protein 2 | / | 0.469 | |
1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.468 | |
1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.468 | |
1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.467 | |
1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.467 | |
1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.467 | |
2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.467 | |
3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.467 | |
4la1 | FAD | Thioredoxin glutathione reductase | / | 0.467 | |
5aga | ANP | DNA polymerase theta | / | 0.467 | |
1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.466 | |
2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.466 | |
2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.466 | |
4dzz | ADP | Plasmid partitioning protein ParF | / | 0.466 | |
4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.466 | |
4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.466 | |
4opg | FDA | Conserved Archaeal protein | / | 0.466 | |
1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.465 | |
1w5t | ADP | ORC1-type DNA replication protein 2 | / | 0.465 | |
2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
2tps | TPS | Thiamine-phosphate synthase | / | 0.465 | |
5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.465 | |
5k5z | ANP | Uncharacterized protein | / | 0.465 | |
2emu | SAH | Diphthine synthase | / | 0.464 | |
2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.464 | |
3bgx | TMP | Thymidylate synthase | / | 0.464 | |
5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.464 | |
1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.463 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.463 | |
3oix | FMN | Dihydroorotate dehydrogenase | / | 0.463 | |
3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.463 | |
2gvd | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.462 | |
2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.462 | |
3gh8 | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 0.462 | |
3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.462 | |
4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.462 | |
1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.461 | |
1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.461 | |
1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.461 | |
1vce | SAH | Diphthine synthase | / | 0.461 | |
1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.461 | |
2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.461 | |
2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.461 | |
2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.461 | |
3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.461 | |
3vhx | GTP | ADP-ribosylation factor 6 | / | 0.461 | |
4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.461 | |
4loi | 1YC | Stimulator of interferon genes protein | / | 0.461 | |
4xye | NAD | Formate dehydrogenase | / | 0.461 | |
1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.460 | |
1j0b | 5PA | Putative 1-aminocyclopropane-1-carboxylate deaminase | 3.5.99.7 | 0.460 | |
1tys | TMP | Thymidylate synthase | / | 0.460 | |
1x1a | SAM | C-20 methyltransferase | / | 0.460 | |
2yvg | NAD | Ferredoxin reductase | / | 0.460 | |
3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.460 | |
4bmv | NAP | Short-chain dehydrogenase | / | 0.460 | |
4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.460 | |
4qxa | GTP | Ras-related protein Rab-9A | / | 0.460 | |
2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.459 | |
2db3 | ANP | ATP-dependent RNA helicase vasa, isoform A | 3.6.4.13 | 0.459 | |
2j7p | GNP | Signal recognition particle protein | / | 0.459 | |
2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.459 | |
3in6 | FMN | Uncharacterized protein | / | 0.459 | |
3jvv | ACP | Twitching mobility protein | / | 0.459 | |
3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.459 | |
3pcr | GTP | ADP-ribosylation factor 6 | / | 0.459 | |
3q1k | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.459 | |
4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.459 | |
4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.459 | |
4rx6 | ATP | Nitrogen regulatory PII-like protein | / | 0.459 | |
1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.458 | |
1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.458 | |
1qf4 | RPD | Adenylosuccinate synthetase | / | 0.458 | |
1rp0 | AHZ | Thiamine thiazole synthase, chloroplastic | / | 0.458 | |
2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.458 | |
3cis | ATP | Universal stress protein Rv2623 | / | 0.458 | |
3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.458 | |
1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.457 | |
2h2a | DND | Probable nicotinate-nucleotide adenylyltransferase | / | 0.457 | |
2p6d | SAH | Diphthine synthase | / | 0.457 | |
3tr0 | 5GP | Guanylate kinase | / | 0.457 | |
4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.457 | |
1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.456 | |
1omo | NAD | Alanine dehydrogenase | / | 0.456 | |
2aa3 | AP0 | L-lactate dehydrogenase | / | 0.456 | |
2y3r | TIR | TamL | / | 0.456 | |
3bc1 | GNP | Ras-related protein Rab-27A | / | 0.456 | |
3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.456 | |
3e5h | GNP | Ras-related protein Rab-28 | / | 0.456 | |
3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.456 | |
3lzs | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.456 | |
4rww | 2BA | Lmo2692 protein | / | 0.456 | |
4ttb | FMN | Iodotyrosine deiodinase 1 | / | 0.456 | |
4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.456 | |
1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.455 | |
1zcb | GDP | Guanine nucleotide-binding protein subunit alpha-13 | / | 0.455 | |
2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.455 | |
2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.455 | |
2g8a | UMP | Thymidylate synthase | / | 0.455 | |
2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.455 | |
1njf | ADP | DNA polymerase III subunit tau | 2.7.7.7 | 0.454 | |
1x1b | SAH | C-20 methyltransferase | / | 0.454 | |
2e17 | SAH | Diphthine synthase | / | 0.454 | |
2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.454 | |
2owk | SAH | Diphthine synthase | / | 0.454 | |
3mx5 | UTP | Nucleoprotein | / | 0.454 | |
3tlx | ADP | Adenylate kinase 2 | / | 0.454 | |
4e07 | ACP | Plasmid partitioning protein ParF | / | 0.454 | |
4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.454 | |
4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.454 | |
4y0v | GDP | ADP-ribosylation factor 1, putative | / | 0.454 | |
4ylg | GDP | ADP-ribosylation factor 1, putative | / | 0.454 | |
4yp1 | 2BA | Stimulator of interferon genes protein | / | 0.454 | |
1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.453 | |
1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.453 | |
1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.453 | |
2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.453 | |
2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.453 | |
3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.453 | |
3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.453 | |
3w8r | ACP | Uridine kinase | / | 0.453 | |
4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.453 | |
4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.453 | |
4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.453 | |
5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.453 | |
5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.453 | |
1b5t | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.452 | |
1cg3 | IMO | Adenylosuccinate synthetase | / | 0.452 | |
1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.452 | |
1ksz | PGS | Adenylosuccinate synthetase | / | 0.452 | |
1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.452 | |
2dsh | SAH | Diphthine synthase | / | 0.452 | |
2ffq | GSP | Ras-related protein Rab-6B | / | 0.452 | |
2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.452 | |
3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.452 | |
3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.452 | |
3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.452 | |
4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.452 | |
4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.452 | |
5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.452 | |
4z36 | ON3 | Lysophosphatidic acid receptor 1 | / | 0.452 | |
1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.451 | |
1g4t | FTP | Thiamine-phosphate synthase | / | 0.451 | |
1orr | NAD | CDP-paratose 2-epimerase | / | 0.451 | |
1p9w | ANP | Type II secretion system protein E | / | 0.451 | |
1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.451 | |
2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.451 | |
2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.451 | |
2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.451 | |
2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.451 | |
2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.451 | |
3lsm | SFD | Pyranose 2-oxidase | / | 0.451 | |
3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
3u4c | NDP | NADPH-dependent reductase BacG | / | 0.451 | |
4dqw | ATP | Inosine-5'-monophosphate dehydrogenase | / | 0.451 | |
4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.451 | |
4i9h | 1E4 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
4kcf | AKM | FAD-dependent oxidoreductase | / | 0.451 | |
5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.451 | |
5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.451 | |
1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.450 | |
1zbd | GTP | Ras-related protein Rab-3A | / | 0.450 | |
1zp4 | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.450 | |
2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.450 | |
2pb6 | SAH | Diphthine synthase | / | 0.450 | |
2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.450 | |
3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.450 | |
3v2u | ATP | Protein GAL3 | / | 0.450 | |
4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.450 | |
4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.450 | |
4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.450 | |
4lol | 1YE | Stimulator of interferon genes protein | / | 0.450 | |
4mok | FAD | Pyranose 2-oxidase | / | 0.450 | |
4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.450 | |
4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.450 | |
5dp2 | NAP | CurF | / | 0.450 | |
1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.449 | |
1j39 | UPG | DNA beta-glucosyltransferase | / | 0.449 | |
1qmg | APX | Ketol-acid reductoisomerase, chloroplastic | 1.1.1.86 | 0.449 | |
1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.449 | |
2e07 | SAH | Diphthine synthase | / | 0.449 | |
2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.449 | |
2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.449 | |
2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.449 | |
2y3r | TRK | TamL | / | 0.449 | |
3gwd | FAD | Cyclohexanone monooxygenase | / | 0.449 | |
3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.449 | |
4yai | NAI | C alpha-dehydrogenase | / | 0.449 | |
5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.449 | |
5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.449 | |
1ow3 | GDP | Transforming protein RhoA | / | 0.448 | |
1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.448 | |
1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.448 | |
2ifa | FMN | Uncharacterized protein | / | 0.448 | |
2qen | ADP | Walker-Type ATPase | / | 0.448 | |
2x3j | ATP | AcsD | / | 0.448 | |
2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.448 | |
3b70 | NAP | Enoyl reductase LovC | 1 | 0.448 | |
3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.448 | |
3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.448 | |
3t1t | GDP | Probable gliding protein mglA | / | 0.448 | |
4amb | DUD | Putative glycosyl transferase | / | 0.448 | |
4bl5 | GFB | GDP-L-fucose synthase | 1.1.1.271 | 0.448 | |
4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.448 | |
4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.448 | |
4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
5ftc | ADP | TPR domain protein | / | 0.448 | |
1ae1 | NAP | Tropinone reductase 1 | / | 0.447 | |
1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.447 | |
1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
2e4n | SAH | Diphthine synthase | / | 0.447 | |
2emr | SAH | Diphthine synthase | / | 0.447 | |
2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
3bbp | GTP | Ras-related protein Rab-6A | / | 0.447 | |
3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.447 | |
3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.447 | |
3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.447 | |
3to0 | FMN | Iodotyrosine deiodinase 1 | 1.21.1.1 | 0.447 | |
3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.447 | |
3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
4z0g | 5GP | Inosine-5'-monophosphate dehydrogenase | / | 0.447 | |
1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
1fxs | NAP | GDP-L-fucose synthase | / | 0.446 | |
1ky2 | GNP | GTP-binding protein YPT7 | / | 0.446 | |
1mbt | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.446 | |
1nzf | UPG | DNA beta-glucosyltransferase | / | 0.446 | |
1qf5 | RPL | Adenylosuccinate synthetase | / | 0.446 | |
2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.446 | |
2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.446 | |
3ge6 | FMN | Nitroreductase | / | 0.446 | |
3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.446 | |
4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.446 | |
4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.446 | |
4jld | ADP | Adenylate kinase | / | 0.446 | |
4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
4u7w | NDP | MxaA | / | 0.446 | |
4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.446 | |
5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.446 | |
1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.445 | |
1lbc | CYZ | Glutamate receptor 2 | / | 0.445 | |
1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.445 | |
1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.445 | |
1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.445 | |
2ax4 | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 2.7.1.25 | 0.445 | |
2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.445 | |
2dsg | SAH | Diphthine synthase | / | 0.445 | |
2ejk | SAH | Diphthine synthase | / | 0.445 | |
2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
2g1y | 5IG | Renin | 3.4.23.15 | 0.445 | |
2gr0 | ADP | Ferredoxin reductase | / | 0.445 | |
2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
2qbu | SAH | Precorrin-2 methyltransferase | / | 0.445 | |
2y4g | TIR | TamL | / | 0.445 | |
2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
3dm5 | GDP | Signal recognition particle 54 kDa protein | / | 0.445 | |
3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.445 | |
3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
3wt0 | ATP | Cell division protein FtsA | / | 0.445 | |
4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.445 | |
1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.444 | |
1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.444 | |
1qcw | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.444 | |
1qor | NDP | Quinone oxidoreductase 1 | / | 0.444 | |
1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.444 | |
2ge3 | ACO | Probable acetyltransferase | / | 0.444 | |
2x0i | NAI | Malate dehydrogenase | / | 0.444 | |
3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.444 | |
3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.444 | |
3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.444 | |
3o7l | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.444 | |
3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.444 | |
4a6r | TA8 | Probable aminotransferase | / | 0.444 | |
4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.444 | |
4xyb | NDP | Formate dehydrogenase | / | 0.444 | |
5jyd | NAD | Short chain dehydrogenase | / | 0.444 | |
1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.443 | |
1sxj | AGS | Replication factor C subunit 1 | / | 0.443 | |
1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.443 | |
2ejj | SAH | Diphthine synthase | / | 0.443 | |
2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.443 | |
2hu2 | NAD | C-terminal binding protein 1 | / | 0.443 | |
2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
3a3g | DLZ | Lumazine protein | / | 0.443 | |
3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.443 | |
3dvl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.443 | |
3hyo | ADP | Pyridoxal kinase | / | 0.443 | |
3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.443 | |
3jzm | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.443 | |
3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.443 | |
3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.443 | |
3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.443 | |
4e09 | ACP | Plasmid partitioning protein ParF | / | 0.443 | |
4pzr | COA | Histone acetyltransferase p300 | / | 0.443 | |
4rpj | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
4xsv | CTP | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.443 | |
1dvr | ATF | Adenylate kinase | / | 0.442 | |
1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
1ib6 | NAD | Malate dehydrogenase | / | 0.442 | |
1kol | NAD | Glutathione-independent formaldehyde dehydrogenase | / | 0.442 | |
1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.442 | |
1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.442 | |
1qm5 | PLP | Maltodextrin phosphorylase | 2.4.1.1 | 0.442 | |
1uma | IN2 | Prothrombin | 3.4.21.5 | 0.442 | |
2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
2jah | NDP | Clavaldehyde dehydrogenase | / | 0.442 | |
2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
3eo8 | FMN | Putative nitroreductase | / | 0.442 | |
3ieu | GDP | GTPase Era | / | 0.442 | |
3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
3nut | SAH | Precorrin-3 methylase | / | 0.442 | |
3thy | ADP | DNA mismatch repair protein Msh2 | / | 0.442 | |
4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.442 | |
4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.442 | |
4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.442 | |
4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
4rkf | GNP | Ras-related protein Rab-3 | / | 0.442 | |
5doz | NDP | JamJ | / | 0.442 | |
1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.441 | |
1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.441 | |
1vik | BAY | Gag-Pol polyprotein | / | 0.441 | |
1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.441 | |
1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.441 | |
2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.441 | |
2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.441 | |
2fhn | BNI | Avidin-related protein 4/5 | / | 0.441 | |
2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.441 | |
2giv | ACO | Histone acetyltransferase KAT8 | / | 0.441 | |
2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.441 | |
2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.441 | |
2owf | SAH | Diphthine synthase | / | 0.441 | |
2pck | SAH | Diphthine synthase | / | 0.441 | |
2quj | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.441 | |
2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.441 | |
3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
3tkl | GTP | Ras-related protein Rab-1A | / | 0.441 | |
3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.441 | |
4cym | GCP | Ras-related protein Rab-32 | / | 0.441 | |
4dja | FAD | (6-4) photolyase | / | 0.441 | |
4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.441 | |
4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.441 | |
4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
4h6r | FDA | Proline dehydrogenase | / | 0.441 | |
4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
4prx | ADP | DNA gyrase subunit B | / | 0.441 | |
4tyq | AP5 | Adenylate kinase | / | 0.441 | |
4xw5 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
1bmd | NAD | Malate dehydrogenase | / | 0.440 | |
1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
1noi | NTZ | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.440 | |
1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
1oon | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.440 | |
1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.440 | |
1pjc | NAD | Alanine dehydrogenase | / | 0.440 | |
1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.440 | |
1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.440 | |
2e15 | SAH | Diphthine synthase | / | 0.440 | |
2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.440 | |
2gsd | NAD | Formate dehydrogenase | / | 0.440 | |
2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.440 | |
2y3s | TIR | TamL | / | 0.440 | |
3atr | FDA | Conserved Archaeal protein | / | 0.440 | |
3b1d | PLS | BetaC-S lyase | / | 0.440 | |
3b6z | CO7 | Enoyl reductase LovC | 1 | 0.440 | |
3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.440 | |
3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.440 | |
3jpu | TY4 | Transcriptional activator protein LasR | / | 0.440 | |
4cjq | VXO | Integrase | / | 0.440 | |
4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.440 | |
4gxs | 0YS | Glutamate receptor 2 | / | 0.440 | |
4h9t | HL4 | Phosphotriesterase | / | 0.440 | |
4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.440 | |
4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
5f8e | SAH | Possible transcriptional regulatory protein | / | 0.440 | |
8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 |