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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3onwGDPGuanine nucleotide-binding protein G(i) subunit alpha-1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3onwGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/1.000
4g5qGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.609
3qi2GDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.557
1gp2GDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.549
3qe0GDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.519
5dhaGNPGTP-binding nuclear protein Ran/0.505
1y3aGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.503
3o26NDPSalutaridine reductase/0.500
1cs4GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.499
1w5tANPORC1-type DNA replication protein 2/0.499
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.498
1w5sADPORC1-type DNA replication protein 2/0.498
1bofGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.496
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.494
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.493
2il2LIXRenin3.4.23.150.487
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.486
2f3rG5PGuanylate kinase2.7.4.80.485
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.485
2ql6ADPNicotinamide riboside kinase 1/0.483
4dfg0JVGag-Pol polyprotein3.4.23.160.483
4du82P0Mevalonate diphosphate decarboxylase/0.483
1m2oGNPSmall COPII coat GTPase SAR13.6.50.482
1xtrGNPGTP-binding protein Rheb/0.482
3c16GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.482
2jlaTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.481
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.481
1sxjADPReplication factor C subunit 5/0.480
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.480
2xtnGTPGTPase IMAP family member 2/0.479
4e03ADPPlasmid partitioning protein ParF/0.479
2c29NAPDihydroflavonol 4-reductase/0.478
2ahrNAPPyrroline-5-carboxylate reductase/0.477
3dl0AP5Adenylate kinase/0.477
3tjzGNPADP-ribosylation factor 1/0.477
1szgFNSCytochrome b2, mitochondrial1.1.2.30.476
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.476
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.476
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.475
1u0hGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.475
1xtsGTPGTP-binding protein Rheb/0.475
4loh1SYStimulator of interferon genes protein/0.475
3h86AP5Adenylate kinase/0.474
4cf1IY7Integrase/0.474
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.474
1p0hACOMycothiol acetyltransferase2.3.1.1890.473
2dteNAIGlucose 1-dehydrogenase related protein/0.472
2gilGTPRas-related protein Rab-6A/0.472
4a5lNDPThioredoxin reductase/0.472
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.471
2pj4414Carboxypeptidase B/0.471
3toxNAPPutative oxidoreductase/0.471
1jedADPSulfate adenylyltransferase/0.470
2gv8NDPThiol-specific monooxygenase1.14.130.470
3f3sNADLambda-crystallin homolog/0.470
3lsiFADPyranose 2-oxidase/0.470
4dieC5PCytidylate kinase/0.470
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.470
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.469
4fidGDPG protein alpha subunit, putative/0.469
4lcjNADC-terminal-binding protein 2/0.469
1aztGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.468
1geeNADGlucose 1-dehydrogenase1.1.1.470.468
1gcoNADGlucose 1-dehydrogenase1.1.1.470.467
1giaGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.467
1me6IVSPlasmepsin-23.4.23.390.467
2anb5GPGuanylate kinase2.7.4.80.467
3c14GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.467
4la1FADThioredoxin glutathione reductase/0.467
5agaANPDNA polymerase theta/0.467
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.466
2pauD5M5'-deoxynucleotidase YfbR/0.466
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.466
4dzzADPPlasmid partitioning protein ParF/0.466
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.466
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.466
4opgFDAConserved Archaeal protein/0.466
1j49NADD-lactate dehydrogenase1.1.1.280.465
1w5tADPORC1-type DNA replication protein 2/0.465
2jb4A14Isopenicillin N synthase1.21.3.10.465
2tpsTPSThiamine-phosphate synthase/0.465
5idwNAPShort-chain dehydrogenase/reductase SDR/0.465
5k5zANPUncharacterized protein/0.465
2emuSAHDiphthine synthase/0.464
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.464
3bgxTMPThymidylate synthase/0.464
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.464
1drhNAPDihydrofolate reductase1.5.1.30.463
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.463
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.463
3oixFMNDihydroorotate dehydrogenase/0.463
3otwCOAPhosphopantetheine adenylyltransferase/0.463
2gvdGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.462
2ien017Gag-Pol polyprotein3.4.23.160.462
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.462
3gh8FMNIodotyrosine deiodinase 11.21.1.10.462
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.462
4j7xNAPSepiapterin reductase1.1.1.1530.462
1g6kNADGlucose 1-dehydrogenase1.1.1.470.461
1h65GDPTranslocase of chloroplast 343.6.50.461
1ipeNDPTropinone reductase 21.1.1.2360.461
1vceSAHDiphthine synthase/0.461
1x7hNDPPutative ketoacyl reductase1.3.10.461
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.461
2gjlFMNNitronate monooxygenase1.13.12.160.461
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.461
3vdqNAD3-hydroxybutyrate dehydrogenase/0.461
3vhxGTPADP-ribosylation factor 6/0.461
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.461
4loi1YCStimulator of interferon genes protein/0.461
4xyeNADFormate dehydrogenase/0.461
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.460
1j0b5PAPutative 1-aminocyclopropane-1-carboxylate deaminase3.5.99.70.460
1tysTMPThymidylate synthase/0.460
1x1aSAMC-20 methyltransferase/0.460
2yvgNADFerredoxin reductase/0.460
3umsGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.460
4bmvNAPShort-chain dehydrogenase/0.460
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.460
4qxaGTPRas-related protein Rab-9A/0.460
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.459
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.459
2j7pGNPSignal recognition particle protein/0.459
2j7pGNPSignal recognition particle receptor FtsY/0.459
3in6FMNUncharacterized protein/0.459
3jvvACPTwitching mobility protein/0.459
3mpt1GKMitogen-activated protein kinase 14/0.459
3pcrGTPADP-ribosylation factor 6/0.459
3q1kADPD-alanine--D-alanine ligase A6.3.2.40.459
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.459
4nu5NADPhosphonate dehydrogenase1.20.1.10.459
4rx6ATPNitrogen regulatory PII-like protein/0.459
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.458
1o97FADElectron transfer flavoprotein subunit alpha/0.458
1qf4RPDAdenylosuccinate synthetase/0.458
1rp0AHZThiamine thiazole synthase, chloroplastic/0.458
2iviACWIsopenicillin N synthase1.21.3.10.458
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.458
3cisATPUniversal stress protein Rv2623/0.458
3fhyATPPyridoxal kinase2.7.1.350.458
4i8zG08Gag-Pol polyprotein3.4.23.160.458
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.458
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.457
2h2aDNDProbable nicotinate-nucleotide adenylyltransferase/0.457
2p6dSAHDiphthine synthase/0.457
3tr05GPGuanylate kinase/0.457
4exg916Beta-secretase 13.4.23.460.457
4fxy0W2Neurolysin, mitochondrial3.4.24.160.457
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.456
1omoNADAlanine dehydrogenase/0.456
2aa3AP0L-lactate dehydrogenase/0.456
2y3rTIRTamL/0.456
3bc1GNPRas-related protein Rab-27A/0.456
3bv2P38Mitogen-activated protein kinase 14/0.456
3e5hGNPRas-related protein Rab-28/0.456
3kpbSAMUncharacterized protein MJ0100/0.456
3lzs017Gag-Pol polyprotein3.4.23.160.456
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.456
4rww2BALmo2692 protein/0.456
4ttbFMNIodotyrosine deiodinase 1/0.456
4ycoFMNtRNA-dihydrouridine(16) synthase/0.456
1szfFMNCytochrome b2, mitochondrial1.1.2.30.455
1zcbGDPGuanine nucleotide-binding protein subunit alpha-13/0.455
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.455
2bslFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.455
2g8aUMPThymidylate synthase/0.455
2yxuATPPyridoxal kinase2.7.1.350.455
3em3478Gag-Pol polyprotein3.4.23.160.455
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.455
3nxxNDPDihydrofolate reductase1.5.1.30.455
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
5af7FADAcyl-CoA dehydrogenase/0.455
1njfADPDNA polymerase III subunit tau2.7.7.70.454
1x1bSAHC-20 methyltransferase/0.454
2e17SAHDiphthine synthase/0.454
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.454
2owkSAHDiphthine synthase/0.454
3mx5UTPNucleoprotein/0.454
3tlxADPAdenylate kinase 2/0.454
4e07ACPPlasmid partitioning protein ParF/0.454
4fryNADPutative signal-transduction protein with CBS domains/0.454
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.454
4y0vGDPADP-ribosylation factor 1, putative/0.454
4ylgGDPADP-ribosylation factor 1, putative/0.454
4yp12BAStimulator of interferon genes protein/0.454
1dr3TAPDihydrofolate reductase1.5.1.30.453
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.453
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.453
1xseNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.453
2tprFADTrypanothione reductase1.8.1.120.453
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.453
3a6pGTPGTP-binding nuclear protein Ran/0.453
3p0fBAUUridine phosphorylase 22.4.2.30.453
3w8rACPUridine kinase/0.453
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.453
4h1vGNPDynamin-1-like protein3.6.5.50.453
4nauAGSPhosphopantetheine adenylyltransferase/0.453
5jljGNPGTP-binding nuclear protein Ran/0.453
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.453
1b5tFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.452
1cg3IMOAdenylosuccinate synthetase/0.452
1f0yNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
1gilGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.452
1kszPGSAdenylosuccinate synthetase/0.452
1sq5ADPPantothenate kinase2.7.1.330.452
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.452
2dshSAHDiphthine synthase/0.452
2ffqGSPRas-related protein Rab-6B/0.452
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.452
3oibFDAPutative acyl-CoA dehydrogenase/0.452
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.452
3tog079Gag-Pol polyprotein2.7.7.490.452
4dpy2P0Mevalonate diphosphate decarboxylase/0.452
4hwkNAPSepiapterin reductase1.1.1.1530.452
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.452
5ckuFADL-ornithine N(5)-monooxygenase/0.452
4z36ON3Lysophosphatidic acid receptor 1/0.452
1bxoPP7Penicillopepsin-13.4.23.200.451
1g4tFTPThiamine-phosphate synthase/0.451
1orrNADCDP-paratose 2-epimerase/0.451
1p9wANPType II secretion system protein E/0.451
1u1f183Uridine phosphorylase2.4.2.30.451
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.451
2bf4FMNNADPH--cytochrome P450 reductase/0.451
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.451
2q46NAPUncharacterized protein At5g02240/0.451
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.451
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.451
3lsmSFDPyranose 2-oxidase/0.451
3toh079Gag-Pol polyprotein2.7.7.490.451
3u4cNDPNADPH-dependent reductase BacG/0.451
4dqwATPInosine-5'-monophosphate dehydrogenase/0.451
4gcmNAPThioredoxin reductase1.8.1.90.451
4i9h1E4L-lactate dehydrogenase A chain1.1.1.270.451
4kcfAKMFAD-dependent oxidoreductase/0.451
5ch7MD1DMSO reductase family type II enzyme, molybdopterin subunit/0.451
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.451
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.450
1zbdGTPRas-related protein Rab-3A/0.450
1zp4FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.450
2hveADPNucleoside diphosphate kinase A2.7.4.60.450
2pb6SAHDiphthine synthase/0.450
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.450
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3lqfNADGalactitol dehydrogenase/0.450
3oz2FADDigeranylgeranylglycerophospholipid reductase/0.450
3v2uATPProtein GAL3/0.450
4dptAGSMevalonate diphosphate decarboxylase/0.450
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.450
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.450
4lol1YEStimulator of interferon genes protein/0.450
4mokFADPyranose 2-oxidase/0.450
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.450
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
4yxm2BADNA integrity scanning protein DisA/0.450
5dp2NAPCurF/0.450
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.449
1j39UPGDNA beta-glucosyltransferase/0.449
1qmgAPXKetol-acid reductoisomerase, chloroplastic1.1.1.860.449
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.449
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.449
2e07SAHDiphthine synthase/0.449
2ex1C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.449
2oapANPType II secretion system protein (GspE-2)/0.449
2rcyNAPPyrroline-5-carboxylate reductase/0.449
2y3rTRKTamL/0.449
3gwdFADCyclohexanone monooxygenase/0.449
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.449
4yaiNAIC alpha-dehydrogenase/0.449
5dldUD1UDP-N-Acetylglucosamine 2-epimerase/0.449
5irnADPNucleotide binding oligomerization domain containing 2/0.449
1ow3GDPTransforming protein RhoA/0.448
1qrpHH0Pepsin A-43.4.23.10.448
1yb5NAPQuinone oxidoreductase1.6.5.50.448
2ifaFMNUncharacterized protein/0.448
2qenADPWalker-Type ATPase/0.448
2x3jATPAcsD/0.448
2zvbSAHPrecorrin-3 C17-methyltransferase/0.448
3b70NAPEnoyl reductase LovC10.448
3c15GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.448
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.448
3t1tGDPProbable gliding protein mglA/0.448
4ambDUDPutative glycosyl transferase/0.448
4bl5GFBGDP-L-fucose synthase1.1.1.2710.448
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.448
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.448
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
5ftcADPTPR domain protein/0.448
1ae1NAPTropinone reductase 1/0.447
1gotGDPGuanine nucleotide-binding protein G(t) subunit alpha-1/0.447
1qiqACCIsopenicillin N synthase1.21.3.10.447
1qjfACSIsopenicillin N synthase1.21.3.10.447
1w4zNAPPutative ketoacyl reductase1.3.10.447
1x7gNAPPutative ketoacyl reductase1.3.10.447
2e4nSAHDiphthine synthase/0.447
2emrSAHDiphthine synthase/0.447
2w3bNDPDihydrofolate reductase1.5.1.30.447
2z54AB1Gag-Pol polyprotein3.4.23.160.447
3bbpGTPRas-related protein Rab-6A/0.447
3clrFADElectron transfer flavoprotein subunit alpha/0.447
3cluFADElectron transfer flavoprotein subunit alpha/0.447
3fpaDTBATP-dependent dethiobiotin synthetase BioD/0.447
3to0FMNIodotyrosine deiodinase 11.21.1.10.447
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.447
3zoiM2WIsopenicillin N synthase1.21.3.10.447
4z0g5GPInosine-5'-monophosphate dehydrogenase/0.447
1f20NAPNitric oxide synthase, brain1.14.13.390.446
1fxsNAPGDP-L-fucose synthase/0.446
1ky2GNPGTP-binding protein YPT7/0.446
1mbtFADUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.446
1nzfUPGDNA beta-glucosyltransferase/0.446
1qf5RPLAdenylosuccinate synthetase/0.446
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.446
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
2vbdV10Isopenicillin N synthase1.21.3.10.446
3clsFADElectron transfer flavoprotein subunit alpha/0.446
3ge6FMNNitroreductase/0.446
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.446
4d5gFADCyclohexane-1,2-dione hydrolase3.7.1.110.446
4j7uNAPSepiapterin reductase1.1.1.1530.446
4jldADPAdenylate kinase/0.446
4l1xNAPAldo-keto reductase family 1 member C2/0.446
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
4twnB96Ephrin type-A receptor 32.7.10.10.446
4u7wNDPMxaA/0.446
4uirFADOleate hydratase4.2.1.530.446
5i4nATPTyrosine-protein kinase JAK2/0.446
1k5dGNPGTP-binding nuclear protein Ran/0.445
1lbcCYZGlutamate receptor 2/0.445
1psa0ZLPepsin A3.4.23.10.445
1rkxNADCDP-D-glucose-4,6-dehydratase/0.445
1xe55FEPlasmepsin-23.4.23.390.445
1xl5190Gag-Pol polyprotein3.4.23.160.445
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.445
2ax4ADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 22.7.1.250.445
2d1cNAPIsocitrate dehydrogenase [NADP]1.1.1.420.445
2dsgSAHDiphthine synthase/0.445
2ejkSAHDiphthine synthase/0.445
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2g1y5IGRenin3.4.23.150.445
2gr0ADPFerredoxin reductase/0.445
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.445
2qbuSAHPrecorrin-2 methyltransferase/0.445
2y4gTIRTamL/0.445
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.445
3dm5GDPSignal recognition particle 54 kDa protein/0.445
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.445
3keuATPPyridoxal kinase2.7.1.350.445
3vfqAR6Poly [ADP-ribose] polymerase 142.4.2.300.445
3wt0ATPCell division protein FtsA/0.445
4dbzNDPPutative ketoacyl reductase1.3.10.445
4oztP1AEcdysone receptor, putative/0.445
1adfTADAlcohol dehydrogenase E chain1.1.1.10.444
1eq2NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.444
1eveE20Acetylcholinesterase3.1.1.70.444
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.444
1nffNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.444
1qcwFNSCytochrome b2, mitochondrial1.1.2.30.444
1qorNDPQuinone oxidoreductase 1/0.444
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.444
2ge3ACOProbable acetyltransferase/0.444
2x0iNAIMalate dehydrogenase/0.444
3d3wNAPL-xylulose reductase1.1.1.100.444
3ea5GDPGTP-binding nuclear protein Ran/0.444
3gbuATPUncharacterized sugar kinase PH14592.7.10.444
3o7lANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3qt62P0Mevalonate diphosphate decarboxylase/0.444
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.444
3wb2YGPUncharacterized protein MJ0488/0.444
4a6rTA8Probable aminotransferase/0.444
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.444
4iv6FDAIsovaleryl-CoA dehydrogenase/0.444
4xybNDPFormate dehydrogenase/0.444
5jydNADShort chain dehydrogenase/0.444
1dr5NAPDihydrofolate reductase1.5.1.30.443
1h73ANPHomoserine kinase2.7.1.390.443
1sxjAGSReplication factor C subunit 1/0.443
1t2cNAIL-lactate dehydrogenase1.1.1.270.443
2a94AP0L-lactate dehydrogenase1.1.1.270.443
2cv2GSUGlutamate--tRNA ligase6.1.1.170.443
2ejjSAHDiphthine synthase/0.443
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.443
2hu2NADC-terminal binding protein 1/0.443
2ylrNAPPhenylacetone monooxygenase1.14.13.920.443
3a3gDLZLumazine protein/0.443
3d4pNADL-lactate dehydrogenase 11.1.1.270.443
3dvlATPCircadian clock protein kinase KaiC2.7.11.10.443
3hyoADPPyridoxal kinase/0.443
3junAJDPhenazine biosynthesis protein A/B/0.443
3jzmATPCircadian clock protein kinase KaiC2.7.11.10.443
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.443
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.443
3qfaFADThioredoxin reductase 1, cytoplasmic1.8.1.90.443
3qlsNDPDihydrofolate reductase1.5.1.30.443
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.443
4e09ACPPlasmid partitioning protein ParF/0.443
4pzrCOAHistone acetyltransferase p300/0.443
4rpjFADUDP-galactopyranose mutase5.4.99.90.443
4xsvCTPEthanolamine-phosphate cytidylyltransferase2.7.7.140.443
1dvrATFAdenylate kinase/0.442
1g1aNADdTDP-glucose 4,6-dehydratase/0.442
1hb1OCVIsopenicillin N synthase1.21.3.10.442
1ib6NADMalate dehydrogenase/0.442
1kolNADGlutathione-independent formaldehyde dehydrogenase/0.442
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.442
1obbNADAlpha-glucosidase3.2.1.200.442
1qm5PLPMaltodextrin phosphorylase2.4.1.10.442
1umaIN2Prothrombin3.4.21.50.442
2b53D23Cyclin-dependent kinase 22.7.11.220.442
2jahNDPClavaldehyde dehydrogenase/0.442
2zsaADPPantothenate kinase2.7.1.330.442
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3eo8FMNPutative nitroreductase/0.442
3ieuGDPGTPase Era/0.442
3nsh957Beta-secretase 13.4.23.460.442
3nutSAHPrecorrin-3 methylase/0.442
3thyADPDNA mismatch repair protein Msh2/0.442
4bb3KKAIsopenicillin N synthase1.21.3.10.442
4bfzZVZPantothenate kinase2.7.1.330.442
4d2dALA_ALA_ALADi-or tripeptide:H+ symporter/0.442
4dc0NDPPutative ketoacyl reductase1.3.10.442
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.442
4i0i957Beta-secretase 13.4.23.460.442
4rkfGNPRas-related protein Rab-3/0.442
5dozNDPJamJ/0.442
1bk0ACVIsopenicillin N synthase1.21.3.10.441
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.441
1m0b0ZQGag-Pol polyprotein3.4.23.160.441
1ozpACOMycothiol acetyltransferase2.3.1.1890.441
1vikBAYGag-Pol polyprotein/0.441
1xnjADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.441
1zd9GDPADP-ribosylation factor-like protein 8A/0.441
2c12FADNitroalkane oxidase1.7.3.10.441
2dftADPShikimate kinase2.7.1.710.441
2fhnBNIAvidin-related protein 4/5/0.441
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.441
2givACOHistone acetyltransferase KAT8/0.441
2i7pACOPantothenate kinase 32.7.1.330.441
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.441
2owfSAHDiphthine synthase/0.441
2pckSAHDiphthine synthase/0.441
2qujTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.441
2w6cBM4Acetylcholinesterase3.1.1.70.441
2zshGA3Gibberellin receptor GID1A30.441
3lpkZ76Beta-secretase 13.4.23.460.441
3tklGTPRas-related protein Rab-1A/0.441
3w8eNAD3-hydroxybutyrate dehydrogenase/0.441
4cymGCPRas-related protein Rab-32/0.441
4djaFAD(6-4) photolyase/0.441
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.441
4fc7NAPPeroxisomal 2,4-dienoyl-CoA reductase1.3.1.340.441
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.441
4h6rFDAProline dehydrogenase/0.441
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.441
4p13FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
4prxADPDNA gyrase subunit B/0.441
4tyqAP5Adenylate kinase/0.441
4xw5ATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1bmdNADMalate dehydrogenase/0.440
1h85FADFerredoxin--NADP reductase1.18.1.20.440
1hb3SCVIsopenicillin N synthase1.21.3.10.440
1m75NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
1noiNTZGlycogen phosphorylase, muscle form2.4.1.10.440
1o01NADAldehyde dehydrogenase, mitochondrial1.2.1.30.440
1obnASVIsopenicillin N synthase1.21.3.10.440
1oonFMNOxygen-insensitive NAD(P)H nitroreductase/0.440
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.440
1pjcNADAlanine dehydrogenase/0.440
1reqDCAMethylmalonyl-CoA mutase large subunit5.4.99.20.440
1vfrFMNMajor NAD(P)H-flavin oxidoreductase1.6.990.440
2e15SAHDiphthine synthase/0.440
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.440
2gsdNADFormate dehydrogenase/0.440
2q4bNAPUncharacterized protein At5g02240/0.440
2y3sTIRTamL/0.440
3atrFDAConserved Archaeal protein/0.440
3b1dPLSBetaC-S lyase/0.440
3b6zCO7Enoyl reductase LovC10.440
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.440
3f1kNAPUncharacterized oxidoreductase YciK10.440
3jpuTY4Transcriptional activator protein LasR/0.440
4cjqVXOIntegrase/0.440
4dpuAGSMevalonate diphosphate decarboxylase/0.440
4gxs0YSGlutamate receptor 2/0.440
4h9tHL4Phosphotriesterase/0.440
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.440
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.440
5f8eSAHPossible transcriptional regulatory protein/0.440
8dfrNDPDihydrofolate reductase1.5.1.30.440